Standout Papers
- Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model (2012)
- Vaccination with tumor cells expressing IL-15 and IL-15Rα inhibits murine breast and prostate cancer (2014)
- Augmented IL-15Rα Expression by CD40 Activation Is Critical in Synergistic CD8 T Cell-Mediated Antitumor Activity of Anti-CD40 Antibody with IL-15 in TRAMP-C2 Tumors in Mice (2012)
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment
2009
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection
2008
Recognition of a Ubiquitous Self Antigen by Prostate Cancer-Infiltrating CD8 + T Lymphocytes
2008 StandoutScienceNobel
SA-4-1BBL and Monophosphoryl Lipid A Constitute an Efficacious Combination Adjuvant for Cancer Vaccines
2014
Homeostatic Proliferation Plus Regulatory T-Cell Depletion Promotes Potent Rejection of B16 Melanoma
2008
Equilibrium between Host and Cancer Caused by Effector T Cells Killing Tumor Stroma
2008
Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein–α
2010 Science
Multiple Antitumor Mechanisms Downstream of Prophylactic Regulatory T-Cell Depletion
2010 StandoutNobel
Constitutive Expression and Costimulatory Function of LIGHT/TNFSF14 on Human Melanoma Cells and Melanoma-Derived Microvesicles
2005
Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3 + CD25 + CD4 + regulatory T cells
2005 StandoutNobel
Dendritic Cell Targeting of Survivin Protein in a Xenogeneic Form Elicits Strong CD4+ T Cell Immunity to Mouse Survivin
2006 StandoutNobel
Oncoprotein Signaling Mediates Tumor-Specific Inflammation and Enhances Tumor Progression
2009
Gene Therapy of Arthritis with TCR Isolated from the Inflamed Paw
2006
A Combination of Chemoimmunotherapies Can Efficiently Break Self-Tolerance and Induce Antitumor Immunity in a Tolerogenic Murine Tumor Model
2007 StandoutNobel
A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma
2011
Hallmarks of Cancer: The Next Generation
2011 Standout
Local IL-21 Promotes the Therapeutic Activity of Effector T cells by Decreasing Regulatory T Cells Within the Tumor Microenvironment
2008
Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in autoimmune neuroinflammation
2014
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Immunosurveillance ofErbb2Carcinogenesis in Transgenic Mice Is Concealed by a Dominant Regulatory T-Cell Self-Tolerance
2006
Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory
2019
Structure and function of the spleen
2005 Standout
Immunosuppressive networks in the tumour environment and their therapeutic relevance
2005 Standout
Ido expression by dendritic cells: tolerance and tryptophan catabolism
2004 Standout
Innate and adaptive immune cells in the tumor microenvironment
2013 Standout
Homing to suppress: address codes for Treg migration
2005
Homing of antibody secreting cells
2003
Regulatory T Cells in Cancer
2010
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells
2006
Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
2005
Cancer immunoediting from immune surveillance to immune escape
2007
Requirement for Lymphoid Tissue-Inducer Cells in Isolated Follicle Formation and T Cell-Independent Immunoglobulin A Generation in the Gut
2008
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Regulatory T cells, tumour immunity and immunotherapy
2006 Standout
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
2016 Standout
Toll-like receptors on regulatory T cells: expanding immune regulation
2006
Taking dendritic cells into medicine
2007 StandoutNatureNobel
In vivo antigen delivery by aSalmonella typhimurium type III secretion system for therapeutic cancer vaccines
2006
Intestinal IgA Synthesis: A Primitive Form of Adaptive Immunity That Regulates Microbial Communities in the Gut
2006
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen
2005
Intestinal IgA synthesis: regulation of front-line body defences
2003 StandoutNobel
Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment
2006
Regulatory T cells in tumor immunity
2010 StandoutNobel
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
High endothelial venules (HEVs) in human melanoma lesions
2012
Shedding Light on Immunotherapy for Cancer
2004
Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells
2005
Interleukin‐10‐secreting type 1 regulatory T cells in rodents and humans
2006
Cancer-related inflammation
2008 StandoutNature
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Tumors as Organs: Complex Tissues that Interface with the Entire Organism
2010
Relapse or Eradication of Cancer Is Predicted by Peptide-Major Histocompatibility Complex Affinity
2013
Tumor-Infiltrating Lymphocyte Grade Is an Independent Predictor of Sentinel Lymph Node Status and Survival in Patients With Cutaneous Melanoma
2012
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
Infiltration of a Mesothelioma by IFN-γ-Producing Cells and Tumor Rejection after Depletion of Regulatory T Cells
2007
Plasmacytoid Dendritic Cells Induce CD8+ Regulatory T Cells In Human Ovarian Carcinoma
2005
Interleukin-10 and the immune response against cancer: a counterpoint
2005
Roles of regulatory T cells in cancer immunity
2016
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade
2008 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
The Three Es of Cancer Immunoediting
2004 Standout
Tumor-Induced Expansion of Regulatory T Cells by Conversion of CD4+CD25− Lymphocytes Is Thymus and Proliferation Independent
2006
PD-L1/B7H-1 Inhibits the Effector Phase of Tumor Rejection by T Cell Receptor (TCR) Transgenic CD8+ T Cells
2004 StandoutNobel
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells
2012 StandoutNobel
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
2005
Isolated Lymphoid Follicle Formation Is Inducible and Dependent Upon Lymphotoxin-Sufficient B Lymphocytes, Lymphotoxin β Receptor, and TNF Receptor I Function
2003
Targeting the Primary Tumor to Generate CTL for the Effective Eradication of Spontaneous Metastases
2007
IL-17 and Th17 Cells
2009 Standout
Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph node
2005
Two distinctive pathways for recruitment of naïve and primed IgM+B cells to the gut lamina propria
2005 StandoutNobel
Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut
2004 StandoutNobel
CD8+ T Cell Immunity Against a Tumor/Self-Antigen Is Augmented by CD4+ T Helper Cells and Hindered by Naturally Occurring T Regulatory Cells
2005
Homeostatic Proliferation as an Isolated Variable Reverses CD8+ T Cell Anergy and Promotes Tumor Rejection
2006
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+regulatory T cells
2008
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Glycolipid α-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice
2006 StandoutNobel
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
Induced sensitization of tumor stroma leads to eradication of established cancer by T cells
2007
CD4+ T Cells Are Able to Promote Tumor Growth through Inhibition of Tumor-Specific CD8+ T-Cell Responses in Tumor-Bearing Hosts
2005
The Efficacy of Radiotherapy Relies upon Induction of Type I Interferon–Dependent Innate and Adaptive Immunity
2011
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells
2003
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Failure at the Effector Phase: Immune Barriers at the Level of the Melanoma Tumor Microenvironment
2007
Tissue-specific expression of B7x protects from CD4 T cell–mediated autoimmunity
2011 StandoutNobel
Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse
2006
Antibody to Langerin/CD207 localizes large numbers of CD8α + dendritic cells to the marginal zone of mouse spleen
2009 StandoutNobel
Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells.
2005
Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells
2005 StandoutNobel
B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma
2006
Comparative Analysis of Regulatory and Effector T Cells in Progressively Growing versus Rejecting Tumors of Similar Origins
2006
Reciprocal Changes in Tumor Antigenicity and Antigen-specific T Cell Function during Tumor Progression
2004
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel
Survey of naturally occurring CD4 + T cell responses against NY-ESO-1 in cancer patients: Correlation with antibody responses
2003
Works of Ping Yu being referenced
Innocuous IFNγ induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production
2008
Priming of naive T cells inside tumors leads to eradication of established tumors
2004
Tumor-infiltrating T lymphocytes: friends or foes?
2006
The role of stroma in immune recognition and destruction of well-established solid tumors
2006
Increasing Tumor Antigen Expression Overcomes “Ignorance” to Solid Tumors via Crosspresentation by Bone Marrow-Derived Stromal Cells
2002
Signaling via LTβR on the lamina propria stromal cells of the gut is required for IgA production
2002
The complementation of lymphotoxin deficiency with LIGHT, a newly discovered TNF family member, for the restoration of secondary lymphoid structure and function
2002
Complementary Role of CD4+ T Cells and Secondary Lymphoid Tissues for Cross-presentation of Tumor Antigen to CD8+ T Cells
2003
Focus on TILs: prognostic significance of tumor infiltrating lymphocytes in human melanoma.
2009
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Specific T Regulatory Cells Display Broad Suppressive Functions against Experimental Allergic Encephalomyelitis upon Activation with Cognate Antigen
2005
B Cells Control the Migration of a Subset of Dendritic Cells into B Cell Follicles Via CXC Chemokine Ligand 13 in a Lymphotoxin-Dependent Fashion
2002
Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors
2005