Citation Impact
Citing Papers
ICOS Promotes the Function of CD4+ Effector T Cells during Anti-OX40–Mediated Tumor Rejection
2016 StandoutNobel
The ICOS/ICOSL Pathway Is Required for Optimal Antitumor Responses Mediated by Anti–CTLA-4 Therapy
2011
Species Interactions in a Parasite Community Drive Infection Risk in a Wildlife Population
2010 StandoutScience
CD4+CD25−Foxp3− Th1 cells are the source of IL-10–mediated immune suppression in chronic cutaneous leishmaniasis
2007
Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection
2005 StandoutNobel
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 + T lymphocytes are prognostic factors of human ovarian cancer
2007 StandoutNobel
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Conventional T-bet+Foxp3− Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection
2007
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
Functional diversity of helper T lymphocytes
1996 StandoutNature
Susceptibility to Trypanosoma cruzi is modified by a previous non‐related infection
1999
Potent activity of soluble B7RP‐1‐Fc in therapy of murine tumors in syngeneic hosts
2002
ICOS co-stimulatory receptor is essential for T-cell activation and function
2001 StandoutNatureNobel
Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
2015 Standout
The role of B7 co‐stimulation in activation and differentiation ofCD4+and CD8+T cells
1998
Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo
1995 Nature
ICOS is critical for CD40-mediated antibody class switching
2001 Nature
Cutaneous wound reepithelialization is compromised in mice lacking functional Slug (Snai2)
2009
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
2002 StandoutNature
A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment
2000 Standout
The regulation of immunoglobulin E class-switch recombination
2003
Comparable in vivo efficacy of CD28/B7, ICOS/GL50, and ICOS/GL50B costimulatory pathways in murine tumor models: IFNγ-dependent enhancement of CTL priming, effector functions, and tumor specific memory CTL
2003
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
The development of allergic inflammation
2008 StandoutNature
NOD1 and NOD2 signalling links ER stress with inflammation
2016 StandoutNature
Th1 and Th2 subsets: paradigms lost?
1995
Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell–dependent B cell responses
2003
Regenerative activity of the lung after epithelial injury
2012
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
1999 StandoutNature
EMT: 2016
2016 Standout
Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies
2003
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Mucosal immunity and allergic responses: lack of regulation and/or lack of microbial stimulation?
2005
From bench to bedside: stealth of enteroinvasive pathogens
2008
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Transcription factor networks in trophoblast development
2022
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
In the Absence of IL-12, CD4+ T Cell Responses to Intracellular Pathogens Fail to Default to a Th2 Pattern and Are Host Protective in an IL-10−/− Setting
2002
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
The TNF and TNF Receptor Superfamilies
2001 Standout
Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis
2004
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA
2015 StandoutNobel
Role of ICOS versus CD28 in antiviral immunity
2002
The TRAF Family of Signal Transducers Mediates NF-κB Activation by the TRANCE Receptor
1998 StandoutNobel
The right place at the right time: novel B7 family members regulate effector T cell responses
2002
The CD28-Related Molecule ICOS Is Required for Effective T Cell–Dependent Immune Responses
2000
Differential Role of CTLA-4 in Regulation of Resting Memory Versus Naive CD4 T Cell Activation
1998
B7DC/PDL2 Promotes Tumor Immunity by a PD-1–independent Mechanism
2003
Nrf2, the Master Regulator of Anti-Oxidative Responses
2017
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
2009 StandoutNobel
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+T cell responses
1999 StandoutNobel
Mouse Eotaxin Expression Parallels Eosinophil Accumulation during Lung Allergic Inflammation but It Is Not Restricted to a Th2-Type Response
1996
B7x: A widely expressed B7 family member that inhibits T cell activation
2003 StandoutNobel
Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy
2014 StandoutNobel
Stat6 Regulation of In Vivo IL-4 Responses
2000
Cutting Edge: Inducible Costimulator Protein Regulates Both Th1 and Th2 Responses to Cutaneous Leishmaniasis
2002
The B7 Family and Cancer Therapy: Costimulation and Coinhibition
2007 StandoutNobel
Therapeutic Targeting of the Tumor Microenvironment
2021
THE B7 FAMILY REVISITED
2005 Standout
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
2008 StandoutNobel
Inducible Costimulator Costimulates Cytotoxic Activity and IFN-γ Production in Activated Murine NK Cells
2002
Inducible Costimulator Protein Controls the Protective T Cell Response Against Listeria monocytogenes
2002
INDUCTION OF TH1 AND TH2 CD4+T CELL RESPONSES:The Alternative Approaches
1997
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Glycolipid α-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice
2006 StandoutNobel
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
The future of immune checkpoint therapy
2015 StandoutScienceNobel
PD-1 deficiency reveals various tissue-specific autoimmunity by H-2band dose-dependent requirement of H-2g7for diabetes in NOD mice
2008 StandoutNobel
B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome
2007 StandoutNobel
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
2011 StandoutScience
Expression of Interleukin 9 in the Lungs of Transgenic Mice Causes Airway Inflammation, Mast Cell Hyperplasia, and Bronchial Hyperresponsiveness
1998
Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells
2000 StandoutNobel
Impaired germinal center formation and recall T-cell–dependent immune responses in mice lacking the costimulatory ligand B7-H2
2003
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+T cells
2000 StandoutNobel
CD40 AND CD154 IN CELL-MEDIATED IMMUNITY
1998
Programmed death-1 concentration at the immunological synapse is determined by ligand affinity and availability
2007 StandoutNobel
Amelioration of Collagen-Induced Arthritis by Blockade of Inducible Costimulator-B7 Homologous Protein Costimulation
2002
Inducible Costimulator Protein (Icos) Controls T Helper Cell Subset Polarization after Virus and Parasite Infection
2000
Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells
2005 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
IL-12 Is Not Required for Induction of Type 1 Cytokine Responses in Viral Infections
1999
Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation
1999 StandoutScience
Works of Ping Lü being referenced
Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations
2020
Brucella abortus induces a novel cytokine gene expression pattern characterized by elevated IL-10 and IFN-γ in CD4+ T cells
1993
Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation
2016
The role of the slug transcription factor in cell migration during corneal re-epithelialization in the dog
2006
Single-cell RNA sequencing reveals regulatory mechanism for trophoblast cell-fate divergence in human peri-implantation conceptuses
2019
Tyrosine kinase inhibition in diffuse large B-cell lymphoma: molecular basis for antitumor activity and drug resistance of dasatinib
2008
Ultraviolet radiation stimulates expression of Snail family transcription factors in keratinocytes
2007
Nuclear Factor E2-Related Factor-2 Negatively Regulates NLRP3 Inflammasome Activity by Inhibiting Reactive Oxygen Species-Induced NLRP3 Priming
2016
A primary intestinal helminthic infection rapidly induces a gut-associated elevation of Th2-associated cytokines and IL-3
1993
Effects of blocking B7-1 and B7-2 interactions during a type 2 in vivo immune response.
1997
Requirement of CTLA-4 counter receptors for IL-4 but not IL-10 elevations during a primary systemic in vivo immune response.
1995
B7H Costimulates Clonal Expansion of, and Cognate Destruction of Tumor Cells by, CD8+ T Lymphocytes In Vivo
2001
CD40-mediated stimulation contributes to lymphocyte proliferation, antibody production, eosinophilia, and mastocytosis during an in vivo type 2 response, but is not required for T cell IL-4 production.
1996
CD28 dependence of T cell differentiation to IL-4 production varies with the particular type 2 immune response.
1997