Citation Impact
Citing Papers
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
2005 StandoutNobel
A Cluster of Metabolic Defects Caused by Mutation in a Mitochondrial tRNA
2004 Science
PDX-1/VP16 Fusion Protein, Together With NeuroD or Ngn3, Markedly Induces Insulin Gene Transcription and Ameliorates Glucose Tolerance
2005
Sirtuins as regulators of metabolism and healthspan
2012 Standout
Glucose Generates Sub-plasma Membrane ATP Microdomains in Single Islet β-Cells
1999
Emerging Role for Members of the Bcl-2 Family in Mitochondrial Morphogenesis
2009
Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
2009
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Inflammation and metabolic disorders
2006 StandoutNature
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
SIRT3 Regulates Mitochondrial Protein Acetylation and Intermediary Metabolism
2011
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Mechanisms linking obesity with cardiovascular disease
2006 StandoutNature
Respiratory Chain Complexes in Dynamic Mitochondria Display a Patchy Distribution in Life Cells
2010
Caenorhabditis elegans pathways that surveil and defend mitochondria
2014 StandoutNatureNobel
Glutamate uptake
2001 Standout
β-Cell Adaptation to Insulin Resistance
2002
Role of Uncoupling Protein-2 Up-Regulation and Triglyceride Accumulation in Impaired Glucose-Stimulated Insulin Secretion in a β-Cell Lipotoxicity Model Overexpressing Sterol Regulatory Element-Binding Protein-1c
2004
Calcium, ATP, and ROS: a mitochondrial love-hate triangle
2004 Standout
Premature ageing in mice expressing defective mitochondrial DNA polymerase
2004 StandoutNature
The x cystine/glutamate antiporter: A potential target for therapy of cancer and other diseases
2008
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Insulin granule dynamics in pancreatic beta cells
2003
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes
2000
Functional complementation of mitochondrial DNAs: Mobilizing mitochondrial genetics against dysfunction
2009
Molecular Defects in Insulin Secretion in Type-2 Diabetes
2004
SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells
2010
Classification and functions of enteroendocrine cells of the lower gastrointestinal tract
2011
Mitochondria: In Sickness and in Health
2012 Standout
Activation of the Hexosamine Pathway Leads to Deterioration of Pancreatic β-Cell Function through the Induction of Oxidative Stress
2001
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
2008 StandoutNature
The mitochondrial uncoupling-protein homologues
2005
Store-Operated Calcium Channels
2005 Standout
Stable Interactions between Mitochondria and Endoplasmic Reticulum Allow Rapid Accumulation of Calcium in a Subpopulation of Mitochondria
2003
Adenovirus‐mediated silencing of Synaptotagmin 9 inhibits Ca2+‐dependent insulin secretion in islets
2005
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
2014 StandoutNature
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
2006 StandoutNature
Beta-cell mitochondria in the regulation of insulin secretion: a new culprit in Type II diabetes
2000
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Mitochondrial dynamics and apoptosis
2008
Superoxide-mediated activation of uncoupling protein 2 causes pancreatic β cell dysfunction
2003
SLP‐2 is required for stress‐induced mitochondrial hyperfusion
2009
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
Recent progress in the biology and physiology of sirtuins
2009 Nature
A pancreatic islet-specific microRNA regulates insulin secretion
2004 StandoutNature
Mitochondrial Metabolism Sets the Maximal Limit of Fuel-stimulated Insulin Secretion in a Model Pancreatic Beta Cell
2002
EphA-Ephrin-A-Mediated β Cell Communication Regulates Insulin Secretion from Pancreatic Islets
2007
Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling
2010
Fine Tuning Our Cellular Factories: Sirtuins in Mitochondrial Biology
2011
Disruption of xCT inhibits cell growth via the ROS/autophagy pathway in hepatocellular carcinoma
2011
Synaptotagmin‐7 is a principal Ca2+ sensor for Ca2+‐induced glucagon exocytosis in pancreas
2009 StandoutNobel
Mitochondrial sirtuins
2010
Mitochondrial fragmentation caused by phenanthroline promotes mitophagy
2012
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
2013
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
2002 StandoutNobel
The Hallmarks of Aging
2013 Standout
Energy Metabolism in the Liver
2014 Standout
Visualizing Superoxide Production in Normal and Diabetic Rat Islets of Langerhans
2003
Activity-Dependent IGF-1 Exocytosis Is Controlled by the Ca2+-Sensor Synaptotagmin-10
2011 StandoutNobel
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
2009
SIRT5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle
2009
Recent advances into the understanding of mitochondrial fission
2012
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
2008 Standout
Quantitative Assessment of Gene Targeting in Vitroand in Vivo by the Pancreatic Transcription Factor, Pdx1
2002
Life cell quantification of mitochondrial membrane potential at the single organelle level
2007
α-Lipoic Acid: A Multifunctional Antioxidant That Improves Insulin Sensitivity in Patients with Type 2 Diabetes
2000
Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis
2008 StandoutNobel
Mitochondrial Diabetes
2004
Nanoscale distribution of mitochondrial import receptor Tom20 is adjusted to cellular conditions and exhibits an inner-cellular gradient
2011 StandoutNobel
Differential but convergent functions of Ca 2+ binding to synaptotagmin-1 C 2 domains mediate neurotransmitter release
2009 StandoutNobel
Superoxide-mediated activation of uncoupling protein 2 causes pancreatic β cell dysfunction
2003
Push-and-pull regulation of the fusion pore by synaptotagmin-7
2010 StandoutNobel
Cells depleted of mitochondrial DNA (p0) yield insight into physiological mechanisms
1999
Synaptotagmin-1 and -7 are functionally overlapping Ca 2+ sensors for exocytosis in adrenal chromaffin cells
2008 StandoutNobel
Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease
2014
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Increased Uncoupling Protein-2 Levels in β-cells Are Associated With Impaired Glucose-Stimulated Insulin Secretion
2001
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Is Oxidative Stress the Pathogenic Mechanism Underlying Insulin Resistance, Diabetes, and Cardiovascular Disease? The Common Soil Hypothesis Revisited
2004
Functional mapping of disease susceptibility loci using cell biology
2006 StandoutNobel
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
2008 StandoutNobel
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes
2002 Standout
Mammalian Sirtuins: Biological Insights and Disease Relevance
2010 Standout
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Synaptotagmin V and IX isoforms control Ca2+-dependent insulin exocytosis
2004
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
2012 StandoutNobel
Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation
2007
Insulin secretion and differential gene expression in glucose-responsive and -unresponsive MIN6 sublines
2000
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Malonyl-CoA Signaling, Lipid Partitioning, and Glucolipotoxicity
2002
Synaptotagmin VII splice variants α, β, and δ are expressed in pancreatic β‐cells and regulate insulin exocytosis
2007
Reduced Loading of Intracellular Ca2+ Stores and Downregulation of Capacitative Ca2+Influx in Bcl-2–Overexpressing Cells
2000
DNA cleavage in immunoglobulin somatic hypermutation depends onde novoprotein synthesis but not on uracil DNA glycosylase
2005 StandoutNobel
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Uncoupling Protein 2: A Possible Link Between Fatty Acid Excess and Impaired Glucose-Induced Insulin Secretion?
2001
Sirtuins — novel therapeutic targets to treat age-associated diseases
2008
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan
2009
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Oscillations of cyclic AMP in hormone-stimulated insulin-secreting β-cells
2006 Nature
The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
2010
Works of Pierre Maechler being referenced
Regulation of Insulin Secretion by SIRT4, a Mitochondrial ADP-ribosyltransferase
2007
Modulation of Glutamate Generation in Mitochondria Affects Hormone Secretion in INS‐1E Beta Cells
2000
Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells
2003
Increase in cellular glutamate levels stimulates exocytosis in pancreatic β‐cells
2002
Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis
1999 Nature
Free radical modulation of insulin release in INS-1 cells exposed to alloxan
1999
Mitochondrial function in normal and diabetic β-cells
2001 Nature
Mitochondria respond to Ca2+ already in the submicromolar range: correlation with redox state
2002
Hydrogen Peroxide Alters Mitochondrial Activation and Insulin Secretion in Pancreatic Beta Cells
1999
Vesicular storage and secretion of l ‐glutamate from glucagon‐like peptide 1‐secreting clonal intestinal L cells
2005
Pdx1 Level Defines Pancreatic Gene Expression Pattern and Cell Lineage Differentiation
2001
Resveratrol Potentiates Glucose-stimulated Insulin Secretion in INS-1E β-Cells and Human Islets through a SIRT1-dependent Mechanism
2010
Mitochondrial activation and the pyruvate paradox in a human cell line
2004
Functional and morphological abnormalities of mitochondria harbouring the tRNA Leu(UUR) mutation in mitochondrial DNA derived from patients with maternally inherited diabetes and deafness (MIDD) and progressive kidney disease
1999
Continuous monitoring of ATP levels in living insulin secreting cells expressing cytosolic firefly luciferase
1998
Desensitization of Mitochondrial Ca2+ and Insulin Secretion Responses in the Beta Cell
1998
Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA
2008
Hepatic glucose sensing is required to preserve β cell glucose competence
2013
Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic β-cells
1997
Secretagogues Modulate the Calcium Concentration in the Endoplasmic Reticulum of Insulin-secreting Cells
1999
Islet β-cell secretion determines glucagon release from neighbouring α-cells
2003
Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic β-cells
2002
Adenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: effects on cell metabolism and insulin secretion
2002
β-Cell Mitochondria and Insulin Secretion
2002
A high carbohydrate diet does not induce hyperglycaemia in a mitochondrial glycerol-3-phosphate dehydrogenase-deficient mouse
2003
Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells.
1998