Citation Impact
Citing Papers
Evidence of a Role for Insulin-Like Growth Factor Binding Protein (IGFBP)-3 in Metabolic Regulation
2010
Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
2022 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Acromegaly
2006 Standout
Cellular and Gene Expression Responses Involved in the Rapid Growth Inhibition of Human Cancer Cells by RNA Interference-mediated Depletion of Telomerase RNA
2005 StandoutNobel
Growth Hormone Treatment of Non–Growth Hormone-Deficient Growth Disorders
2007
β-Arrestin Is Crucial for Ubiquitination and Down-regulation of the Insulin-like Growth Factor-1 Receptor by Acting as Adaptor for the MDM2 E3 Ligase
2005 StandoutNobel
Testosterone Therapy in Men with Androgen Deficiency Syndromes: An Endocrine Society Clinical Practice Guideline
2010 Standout
Cloning and characterization of an IGF-1 isoform expressed in skeletal muscle subjected to stretch
1996
Insulin- like Growth Factor-Binding Protein Action in Bone Tissue: A Key Role for Pregnancy- Associated Plasma Protein-A
2018
Nutritional Regulation of the Insulin-Like Growth Factors*
1994
Biology of insulin‐like growth factors in development
2003
Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations*
1989 Standout
Distribution and Regulation of Rat Insulin-Like Growth Factor I Messenger Ribonucleic Acids Encoding Alternative Carboxyterminal E-Peptides: Evidence for Differential Processing and Regulation in Liver
1988
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
The Prospective Association of Serum Insulin-Like Growth Factor I (IGF-I) and IGF-Binding Protein-1 Levels with All Cause and Cardiovascular Disease Mortality in Older Adults: The Rancho Bernardo Study
2004
Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study
2002
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
1999 Standout
Insulin‐like growth factors I and II
1990
Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005–2009
2010 Standout
Anthropometric Measures, Body Mass Index, and Pancreatic Cancer
2010
Erectile Dysfunction
2000 Standout
Childhood obesity: public-health crisis, common sense cure
2002 Standout
Cushing's syndrome
2015 Standout
Classification of epilepsies and seizures: historical perspective and future directions
2012
Phosphatidylinositol 3-Kinase Signaling Inhibits DAF-16 DNA Binding and Function via 14-3-3-dependent and 14-3-3-independent Pathways
2001 StandoutNobel
Cellular Senescence in Cancer and Aging
2007 Standout
Classification criteria of epileptic seizures and syndromes
2006
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Pancreatic cancer
2016 Standout
Central obesity and breast cancer risk: a systematic review
2003
Signal transduction by receptors with tyrosine kinase activity
1990 Standout
Variation in GH and IGF‐I assays limits the applicability of international consensus criteria to local practice
2007
The sirtuin SIRT6 regulates lifespan in male mice
2012 Nature
Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor
1998 StandoutNobel
Insulin-Like Growth Factors (IGFs), IGF Receptors, and IGF-Binding Proteins in Primary Cultures of Prostate Epithelial Cells*
1991
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
2006 Nature
Gβγ Subunits Mediate Mitogen-activated Protein Kinase Activation by the Tyrosine Kinase Insulin-like Growth Factor 1 Receptor
1995 StandoutNobel
Obesity
2005 Standout
Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy
2007 StandoutNobel
Increased Activity of Insulin-Like Growth Factor (IGF) in Osteoblastic Cells in the Presence of Growth Hormone (GH): Positive Correlation with the Presence of the GHInduced IGF-Binding Protein BP-3
1990
Clinical Features of Adrenocortical Carcinoma, Prognostic Factors, and the Effect of Mitotane Therapy
1990
Erythropoietic drive is the strongest predictor of hepcidin level in adults with sickle cell disease
2015
Phosphorylation of Serine 256 by Protein Kinase B Disrupts Transactivation by FKHR and Mediates Effects of Insulin on Insulin-like Growth Factor-binding Protein-1 Promoter Activity through a Conserved Insulin Response Sequence
1999
Is a first acute symptomatic seizure epilepsy? Mortality and risk for recurrent seizure
2009
Treatment initiation in epilepsy: An expert consensus in Spain
2010
DNA Damage, Aging, and Cancer
2009 Standout
Polycystic Ovary Syndrome
1995 Standout
The current status of IGF-I assays – A 2009 update
2009
Advances in clinical research in sickle cell disease
2008
Protein Kinase B/Akt Mediates Effects of Insulin on Hepatic Insulin-like Growth Factor-binding Protein-1 Gene Expression through a Conserved Insulin Response Sequence
1998
Magnetic resonance imaging of adrenocortical adenomas in childhood: Correlation with computed tomography and ultrasound
1996
Acromegaly: An Endocrine Society Clinical Practice Guideline
2014 Standout
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
The new ILAE report on terminology and concepts for organization of epileptic seizures: A clinician’s critical view and contribution
2011
What is the role of circulating IGF-I?
2001
Recommendation for a definition of acute symptomatic seizure
2009
Sickle-cell disease
2010 Standout
Polycystic Ovary Syndrome
2005 Standout
The specificity of the human IGF-2 receptor
1987
Molecular Forms of Serum Insulin-Like Growth Factor (IGF)-Binding Proteins in Man: Relationships with Growth Hormone and IGFs and Physiological Significance*
1989
New Approach to Polycystic Ovary Syndrome and Other Forms of Anovulatory Infertility
2002
Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
2008 Standout
Insulin Inhibits the Activation of Transcription by a C-terminal Fragment of the Forkhead Transcription Factor FKHR
2000
Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
1999 StandoutNobel
Specificity of insulin-like growth factor binding to type-II IGF receptors in rabbit mammary gland and hypophysectomized rat liver
1987
Sustained benefit after 2 years of growth hormone on body composition, fat utilization, physical strength and agility, and growth in Prader-Willi syndrome
2000
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
1998 StandoutNature
β-Arrestin and Mdm2 Mediate IGF-1 Receptor-stimulated ERK Activation and Cell Cycle Progression
2007 StandoutNobel
Role of the Insulin-Like Growth Factor Family in Cancer Development and Progression
2000
Insulin‐Like Growth Factor Receptors
1991
The Hallmarks of Aging
2013 Standout
Common imitators of epilepsy
2012
Insulin-like Growth Factor-I in Muscle Metabolism and Myotherapies
2001
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Report of the ILAE Classification Core Group
2006
Frailty in elderly people
2013 Standout
Molecular and Cellular Aspects of the Insulin-Like Growth Factor I Receptor
1995
Investigation of insulin-like growth factors/insulin-like growth factor binding proteins regulation in metabolic syndrome patients
2019
Efficacy and safety of deferasirox compared with deferoxamine in sickle cell disease: Two‐year results including pharmacokinetics and concomitant hydroxyurea
2013
Liver iron concentration measurements by MRI in chronically transfused children with sickle cell anemia: baseline results from the TWiTCH trial
2015
Improvement of Sexual Function in Testosterone Deficient Men Treated for 1 Year with a Permeation Enhanced Testosterone Transdermal System
1996
Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology
2017 Standout
Glucocorticoids and insulin regulate expression of the human gene for insulin-like growth factor-binding protein-1 through proximal promoter elements.
1994
Molecular Control of Immune/Inflammatory Responses: Interactions Between Nuclear Factor-κB and Steroid Receptor-Signaling Pathways
1999
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
1993 Standout
Hepatic Nuclear Factor 3- and Hormone-Regulated Expression of the Phosphoenolpyruvate Carboxykinase and Insulin-Like Growth Factor-Binding Protein 1 Genes
1995
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
2000 StandoutNobel
Obesity, endogenous hormones, and endometrial cancer risk: a synthetic review.
2002
Insulin-like Growth Factors (IGF) in Muscle Development
1989
Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: A possible model for IGFBP-1 expression in fetal hypoxia
1998
Role of insulin-like growth factors in embryonic and postnatal growth
1993 Standout
Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor
2003
Diabetes and Cancer
2010 Standout
Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study
1998 StandoutScience
ILAE Official Report: A practical clinical definition of epilepsy
2014 Standout
Regulation of the mannose 6-phosphate/IGF II receptor expression at the cell surface by mannose 6-phosphate, insulin like growth factors and epidermal growth factor.
1989 StandoutNobel
Insulin-like growth factor II receptor as a multifunctional binding protein
1987 Nature
40 YEARS OF IGF1: Role of IGF-binding proteins in regulating IGF responses to changes in metabolism
2018
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Effect of an anti-insulin-like growth factor I receptor antibody on insulin-like growth factor II stimulation of DNA synthesis in human fibroblasts
1986
Organ iron accumulation in chronically transfused children with sickle cell anaemia: baseline results from the TW iTCH trial
2015
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2007 StandoutScience
Glucocorticoid Action and the Clinical Features of Cushing’s Syndrome
1994
Hepatic Nuclear Factor 3 and High Mobility Group I/Y Proteins Bind the Insulin Response Element of the Insulin-Like Growth Factor-Binding Protein-1 Promoter*
1997
The cation-independent mannose 6-phosphate receptor binds insulin-like growth factor II.
1988
Treatment of Pituitary Gigantism with the Growth Hormone Receptor Antagonist Pegvisomant
2008
Identification of cis-elements mediating the stimulation of rat insulin-like growth factor-binding protein-1 promoter activity by dexamethasone, cyclic adenosine 3',5'-monophosphate, and phorbol esters, and inhibition by insulin.
1994
Structure of the Receptor for Insulin-Like Growth Factor II: The Puzzle Amplified
1988 Science
Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
2011 StandoutNobel
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Insulin as an Effector of Human Ovarian and Adrenal Steroid Metabolism
1991
Differential signalling potential of insulin- and IGF-1-receptor cytoplasmic domains.
1989
An antibody that blocks insulin-like growth factor (IGF) binding to the type II IGF receptor is neither an agonist nor an inhibitor of IGF-stimulated biologic responses in L6 myoblasts.
1987
FKHR Binds the Insulin Response Element in the Insulin-Like Growth Factor Binding Protein-1 Promoter*
1999
Insulin-like growth factor II stimulates calcium influx in competent BALB/c 3T3 cells primed with epidermal growth factor. Characteristics of calcium influx and involvement of GTP-binding protein.
1987
American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Diagnosis and Treatment of Acromegaly-2011 Update
2011
Deletion, But Not Antagonism, of the Mouse Growth Hormone Receptor Results in Severely Decreased Body Weights, Insulin, and Insulin-Like Growth Factor I Levels and Increased Life Span
2003
Global Fibrinolytic Capacity Is Decreased in Polycystic Ovary Syndrome, Suggesting a Prothrombotic State
2002
Works of Phillip Lee being referenced
Receptor binding and mitogenic effects of insulin and insulinlike growth factors I and II for human myeloid leukemic cells
1987
Insulin Regulation of Insulin-Like Growth Factor-Binding Protein Production in Cultured HepG2 Cells*
1990
Insulin-Like Growth Factors and Insulin-Like Growth Factor Binding Proteins in Adult Patients with Severe Liver Disease before and after Orthotopic Liver Transplantation
2002
Comparison of organ dysfunction in transfused patients with SCD or β thalassemia
2005
Insulin-like growth factor-binding protein-1 expression in cultured human bone cells: regulation by insulin and glucocorticoid.
1996
Increased prevalence of iron‐overload associated endocrinopathy in thalassaemia versus sickle‐cell disease
2006
Insulin-like growth factor-binding protein-3 is partially responsible for high-serum-induced apoptosis in PC-3 prostate cancer cells
1999
Quantitative ontogeny of murine insulin-like growth factor (IGF)-I, IGF-binding protein-3 and the IGF-related acid-labile subunit
2007
Cortisol increases plasma insulin-like growth factor binding protein-1 in humans
1993
Insulin-like growth factor-binding protein-1 response to insulin during suppression of endogenous insulin secretion
1993
Management of type 2 diabetes mellitus associated with pituitary gigantism
2007
Multihormonal Regulation of IGFBP-1 Promoter Activity
1994
Insulin-Like Growth Factor (IGF) Binding Protein Complementary Deoxyribonucleic Acid from Human HEP G2 Hepatoma Cells: Predicted Protein Sequence Suggests an IGF Binding Domain Different from Those of the IGF-I and IGF-II Receptors
1988
Body Composition Studies in Prader-Willi Syndrome: Effects of Growth Hormone Therapy
1993
Insulin-like Growth Factor Binding Protein-1: Recent Findings and New Directions
1997
Bioactivity of a 29-Kilodalton Insulin-Like Growth Factor Binding Protein-3 Fragment Present in Excess in Chronic Renal Failure Serum
1997
Antiserum Developed for the E Peptide Region of Insulin-Like Growth Factor IA Prohormone Recognizes a Serum Protein by Both Immunoblot and Radioimmunoassay*
1987
Elevated Serum Levels of Free Insulin-Like Growth Factor I in Polycystic Ovary Syndrome1
1999
Modulation of growth factors by growth hormone in children with chronic renal failure
1997
Epileptic Seizures and Epilepsy: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)
2005 Standout
Regulation and Function of Insulin-Like Growth Factor-Binding Protein-1
1993
IGF Binding Proteins in Growth-Retarded Children with Chronic Renal Failure
1989
Virilizing Adrenocortical Tumors in Childhood: Eight Cases and a Review of the Literature
1985
Insulin regulation of insulin-like growth factor binding protein-1 in obese and nonobese humans.
1992
Role of protein kinase-C in regulation of insulin-like growth factor-binding protein-1 production by HepG2 cells.
1992
Psychosexual behavior in hypopituitary men: A controlled comparison of gonadotropin and testosterone replacement
1993
Dexamethasone stimulates expression of insulin-like growth factor binding protein-1 in HEP G2 human hepatoma cells.
1993
Noncompetitive ELISA for human serum insulin-like growth factor-I
1996
Characterization of Insulin, Insulin-Like Growth Factors I and II, and Growth Hormone Receptors on Human Leukemic Lymphoblasts*
1986
Purification of the Insulin-like growth factor II (IGF-II) receptor from an IGF-II-producing cell line, and generation of an antibody which both immunoprecipitates and blocks the type 2 IGF receptor
1986
Relationship between non-enzymatic glycosylation and changes in serum insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 levels in patients with type 2 diabetes mellitus
1998
Identification of a promoter element which participates in cAMP-stimulated expression of human insulin-like growth factor-binding protein-1
1993
Insulin-like growth factors I and II in evaluation of growth retardation
1986
Response: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)
2005
Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1.
1991
Lack of Growth Hormone Effect on Insulin-Associated Suppression of Insulinlike Growth Factor Binding Protein 1 in Humans
1990
A randomized, placebo-controlled trial of combined insulin-like growth factor I and low dose growth hormone therapy for wasting associated with human immunodeficiency virus infection.
1996
Heterogeneity of insulin-like growth factor-I affinity for the insulin-like growth factor-II receptor: Comparison of natural, synthetic and recombinant DNA-derived insulin-like growth factor-I
1987
The Insulin-Like Growth Factor Axis and Plasma Lipid Levels in the Elderly1
1998
Identification of receptors for insulin-like growth factor II in two insulin-like growth factor II producing cell lines
1986