Citation Impact
Citing Papers
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
2009 StandoutScience
Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity
2013 StandoutNobel
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Exploring and Exploiting the Therapeutic Potential of Glycoconjugates
2005
Roles of NAD / NADH and NADP+ / NADPH in Cell Death
2009
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
MYC on the Path to Cancer
2012 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Chromatin Modifications and Their Function
2007 Standout
Chemoenzymatic Fc Glycosylation via Engineered Aldehyde Tags
2014 StandoutNobel
Ligand amplification in a dynamic combinatorial glycopeptide library
2005
Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation
2013
Preparation of Pixantrone/Poly(γ‐glutamic acid) Nanoparticles through Complex Self‐Assembly for Oral Chemotherapy
2012
Poly(ADP-ribose)polymerase 1 (PARP-1) and postischemic brain damage
2007
Glycopeptide dendrimers. Part I
2007
Cell-Based Assays for High-Throughput Screening
2010
The neurobiology of zinc in health and disease
2005 Standout
The GPR54 Gene as a Regulator of Puberty
2003 Standout
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
2014 Standout
Oxidative stress and cancer: An overview
2012
Design and Synthesis of a Homogeneous Erythropoietin Analogue with Two Human Complex‐Type Sialyloligosaccharides: Combined Use of Chemical and Bacterial Protein Expression Methods
2009 StandoutNobel
Glycopeptide dendrimers. Part II
2007
The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
2016 Standout
Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiaegene function
2008
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
2012 Standout
Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator
2008
Necrotic death as a cell fate
2006
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Chemical-genomic profiling: Systematic analysis of the cellular targets of bioactive molecules
2011
Magnetic Resonance Spectroscopy for Monitoring Neuronal Integrity in Amyotrophic Lateral Sclerosis
2006
Exploring genetic interactions and networks with yeast
2007
N-Acetylaspartate in the CNS: From neurodiagnostics to neurobiology
2007 Standout
Immunity, Inflammation, and Cancer
2010 Standout
Caspase-independent cell death
2005
Chemoselective Ligation and Modification Strategies for Peptides and Proteins
2008
Chemical Approaches To Perturb, Profile, and Perceive Glycans
2009 StandoutNobel
A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer
2011
Origin and physiological roles of inflammation
2008 StandoutNature
Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer
2012 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Role of Poly(ADP‐ribose) polymerase 1 (PARP‐1) in Cardiovascular Diseases: The Therapeutic Potential of PARP Inhibitors
2007
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
2009 Standout
Reduced N-Acetylaspartate Levels in Mice Lacking Aralar, a Brain- and Muscle-type Mitochondrial Aspartate-glutamate Carrier
2005
Delayed changes in T1‐weighted signal intensity in a rat model of 15‐minute transient focal ischemia studied by magnetic resonance imaging/spectroscopy and synchrotron radiation X‐ray fluorescence
2006
Increased N-acetylaspartate in rat striatum following long-term administration of haloperidol
2004
The PARP superfamily
2004
Potent 5-nitrofuran derivatives inhibitors of Trypanosoma cruzi growth: Electrochemical, spectroscopic and biological studies
2011
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Antibacterial drug discovery in the resistance era
2016 StandoutNature
Synthetic lethality: General principles, utility and detection using genetic screens in human cells
2010
Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting
2009
N‐Acetylaspartate: a literature review of animal research on brain ischaemia
2004
NAD + /NADH and NADP + /NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences
2007 Standout
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Nuclear ADP-Ribosylation Reactions in Mammalian Cells: Where Are We Today and Where Are We Going?
2006
Episodic Luteinizing Hormone Secretion in Man PULSE ANALYSIS, CLINICAL INTERPRETATION, PHYSIOLOGIC MECHANISMS
1973
Mapping of Functional Groups in Metal-Organic Frameworks
2013 StandoutScienceNobel
Luminescent Chemodosimeters for Bioimaging
2012 Standout
Hypothalamic Regulatory Hormones
1973 StandoutScienceNobel
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
The power to reduce: pyridine nucleotides – small molecules with a multitude of functions
2007
A “Tag-and-Modify” Approach to Site-Selective Protein Modification
2011
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Fluorescence Lifetime Measurements and Biological Imaging
2010 Standout
Dynamic Combinatorial Chemistry
2006 Standout
Chemical Approaches to Glycobiology
2010
Schwann cell chemokine receptors mediate HIV‐1 gp120 toxicity to sensory neurons
2003
New Targets and Screening Approaches in Antimicrobial Drug Discovery
2005
Stimulation of Adenosine 3′:5′-Cyclic Monophosphate Accumulation in Anterior Pituitary Gland In Vitro by Synthetic Luteinizing Hormone-Releasing Hormone
1972 StandoutNobel
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Comprehensive Survey of Combinatorial Library Synthesis: 2005
2006
Membrane Protein Topology Probed by 1H Spin Diffusion from Lipids Using Solid-State NMR Spectroscopy
2002
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury
2010 StandoutNobel
HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury
2010 StandoutNobel
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Chemoselektive Ligations‐ und Modifikationsstrategien für Peptide und Proteine
2008
Glycoprotein Synthesis: An Update
2008
Synthetic Routes to Thiooligosaccharides and Thioglycopeptides
2005
Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
2011 StandoutNobel
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Generation and Detection of Reactive Oxygen Species in Photocatalysis
2017 Standout
The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets
2020 Standout
Next generation diversity-oriented synthesis: a paradigm shift from chemical diversity to biological diversity
2018
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Catalytic Asymmetric Synthesis of Thiols
2014 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action
2004
Advances in Chemical Protein Modification
2015
Discovery of Long-Wavelength Photoactivatable Diaryltetrazoles for Bioorthogonal 1,3-Dipolar Cycloaddition Reactions
2008
Works of Philippe Garnier being referenced
P2X7 receptors mediate NADH transport across the plasma membranes of astrocytes
2007
Zinc release contributes to hypoglycemia-induced neuronal death
2004
Regioselective Photolabeling of Glycophorin A in Membranes
2002
Glycosyl phenylthiosulfonates (Glyco-PTS): novel reagents for glycoprotein synthesisThis is one of a number of contributions from the current members of the Dyson Perrins Laboratory to mark the end of almost 90 years of organic chemistry research in that building, as all its current academic staff move across South Parks Road to a new purpose-built laboratory.Electronic supplementary information (ESI) available: experimental procedures, characterization, protein ESI-MS spectra and crystal data. See http://www.rsc.org/suppdata/ob/b3/b306990g/
2003
Discovering Modes of Action for Therapeutic Compounds Using a Genome-Wide Screen of Yeast Heterozygotes
2004
Evidence of HIF-1 functional binding activity to caspase-3 promoter after photothrombotic cerebral ischemia
2006
Glyco‐SeS: Selenenylsulfide‐Mediated Protein Glycoconjugation—A New Strategy in Post‐Translational Modification
2004
Mid-Membrane Photolabeling of the Transmembrane Domain of Glycophorin A in Phospholipid Vesicles
2001
NAD+ as a metabolic link between DNA damage and cell death
2004
N‐Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury
2001
NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes
2003
NAD+Depletion Is Necessary and Sufficient forPoly(ADP-Ribose) Polymerase-1-Mediated Neuronal Death
2010
Ischemic Preconditioning by Caspase Cleavage of Poly(ADP-Ribose) Polymerase-1
2003
Hypoglycemic Neuronal Death and Cognitive Impairment Are Prevented by Poly(ADP-Ribose) Polymerase Inhibitors Administered after Hypoglycemia
2003
Glyco‐SeS: Selenenylsulfide‐Mediated Protein Glycoconjugation—A New Strategy in Post‐Translational Modification
2004
[Synthesis of LH-RH and selective effect on the release of luteotropic hormone in human adults].
1971
Oxidosqualene Cyclase Inhibitors as Antimicrobial Agents
2003
LEAPT: Lectin-directed enzyme-activated prodrug therapy
2004
Reversible Loss ofN-Acetyl-Aspartate in Rats Subjected to Long-Term Focal Cerebral Ischemia
2003