Standout Papers
Citation Impact
Citing Papers
A Small-Molecule Modulator of Poly-α2,8-Sialic Acid Expression on Cultured Neurons and Tumor Cells
2001 StandoutScienceNobel
CYCLE Is a Second bHLH-PAS Clock Protein Essential for Circadian Rhythmicity and Transcription of Drosophila period and timeless
1998 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Delta-1 Activation of Notch-1 Signaling Results in HES-1 Transactivation
1998
Within Germinal Centers, Isotype Switching of Immunoglobulin Genes Occurs after the Onset of Somatic Mutation
1996
A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumour virus
1991 Nature
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
1993 Standout
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
1995 StandoutNatureNobel
Skeletal muscles of mice deficient in muscle creatine kinase lack burst activity
1993
Regulation of XSnail2 expression by Rho GTPases
2007
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
The Hallmarks of Cancer
2000 Standout
Reshaping human antibodies for therapy
1988 StandoutNatureNobel
Developmental regulation of MHC class II transport in mouse dendritic cells
1997 StandoutNatureNobel
Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
1995 Standout
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
1994 Nature
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Expression of the neural cell adhesion molecule and polysialic acid during early mouse embryogenesis
1994
Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
1993 StandoutNatureNobel
Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question
1992 StandoutNobel
Crisscross regulation of cell-type-specific gene expression during development in B. subtilis
1992 Nature
Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase
1992 Nature
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
Synapse-Specific, Long-Term Facilitation of Aplysia Sensory to Motor Synapses: A Function for Local Protein Synthesis in Memory Storage
1997 StandoutNobel
Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA
1995 Nature
MicroReview Cascades of sigma factors revisited
1990
A Multigene Family Encoding a Diverse Array of Putative Pheromone Receptors in Mammals
1997 StandoutNobel
E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation
1996 StandoutNobel
Epidermal growth factor activates calcium channels by phospholipase A25-lipoxygenase-mediated leukotriene C4 production
1992
GEFs and GAPs: Critical Elements in the Control of Small G Proteins
2007
Removal of phosphorylation sites from the β2-adrenergic receptor delays onset of agonist-promoted desensitization
1988 StandoutNatureNobel
The Circadian Gene Period2 Plays an Important Role in Tumor Suppression and DNA Damage Response In Vivo
2002
Processing of a sporulation sigma factor in Bacillus subtilis: How morphological structure could control gene expression
1988
Rho and Rac Take Center Stage
2004 Standout
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
1992 Standout
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
A gene regulatory network orchestrates neural crest formation
2008
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
Eomesodermin is required for mouse trophoblast development and mesoderm formation
2000 StandoutNatureNobel
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
2001 Standout
Protein Synthesis Inhibitors Reveal Differential Regulation of Mitogen-Activated Protein Kinase and Stress-Activated Protein Kinase Pathways That Converge on Elk-1
1995
Increased rate of degradation of c-myc mRNA in interferon-treated Daudi cells.
1985
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
The human ubiquitin multigene family: some genes contain multiple directly repeated ubiquitin coding sequences.
1985
Small GTP-Binding Proteins
2001 Standout
Role of arginine-tRNA in protein degradation by the ubiquitin pathway
1987 StandoutNatureNobel
Human cervical and foreskin epithelial cells immortalized by human papillomavirus DNAs exhibit dysplastic differentiation in vivo.
1990
Quality Control by DNA Repair
1999 StandoutScienceNobel
Functional Role of Type I and Type II Interferons in Antiviral Defense
1994 StandoutScience
An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins
1987 StandoutNatureNobel
Establishment of Cell Type by Compartmentalized Activation of a Transcription Factor
1991 Science
Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions.
1987 StandoutNobel
Identification of a new sigma-factor involved in compartmentalized gene expression during sporulation of Bacillus subtilis.
1989
Expression of a conserved cell-type-specific protein in nerve terminals coincides with synaptogenesis.
1991
Controlling mRNA lifespan
1988 StandoutNatureNobel
DNA sequences that mediate attenuation of transcription from the mouse protooncogene myc.
1989 StandoutNobel
c-myc gene is transcribed at high rate in G0-arrested fibroblasts and is post-transcriptionally regulated in response to growth factors
1985 Nature
Posttranscriptional mechanisms are responsible for accumulation of truncated c-myc RNAs in murine plasma cell tumors
1985
Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas.
1995
The cancer connection
2002 StandoutNatureNobel
Viruses in Human Cancers
1991 StandoutScienceNobel
Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase.
1995
Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.
1991
Continuous human cell lines inducibly expressing hepatitis C virus structural and nonstructural proteins
1998 StandoutNobel
Control of developmental transcription factor sigma F by sporulation regulatory proteins SpoIIAA and SpoIIAB in Bacillus subtilis.
1990
Analysis of the Mouse dhfr Promoter Region: Existence of a Divergently Transcribed Gene
1985
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α 2 -Adrenergic Receptor
1987 StandoutScienceNobel
Evidence for distinct signaling mechanisms in two mammalian olfactory sense organs.
1996 StandoutNobel
Apoptosis in AIDS
1993 StandoutScienceNobel
Promotion of Trophoblast Stem Cell Proliferation by FGF4
1998 Science
Selective degradation of early-response-gene mRNAs: functional analyses of sequence features of the AU-rich elements.
1994
Intragenic pausing and anti-sense transcription within the murine c-myc locus.
1986
Characterization of rhoGAP. A GTPase-activating protein for rho-related small GTPases.
1994
Selective Degradation of Early-Response-Gene mRNAs: Functional Analyses of Sequence Features of the AU-Rich Elements
1994
Temporal and spatial control of the mother-cell regulatory gene spoIIID of Bacillus subtilis.
1989
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Introduction to Theme “Chromatin, Epigenetics, and Transcription”
2012
Works of Philippe Fort being referenced
S26 ribosomal protein RNA: an invariant control for gene regulation experiments in eucaryotic cells and tissues
1993
Expression of RhoB in the developing Xenopus laevis embryo
2006
A Dual Role of the GTPase Rac in Cardiac Differentiation of Stem Cells
2003
The small GTPase RhoV is an essential regulator of neural crest induction in Xenopus
2007
Identification of TRIO‐GEFD1 chemical inhibitors using the yeast exchange assay
2006
Regulation of c-fosgene expression in hamster fibroblasts: initiation and elongation of transcription and mRNA degradation
1987
Nucleotide Sequence and Complementation Analysis of a Polycistronic Sporulation Operon, spoVA, in Bacillus subtilis
1985
Growth-regulated expression of rhoG, a new member of the ras homolog gene family.
1992
Duplicated sporulation genes in bacteria
1985
Characterization of the transcription products of glyceraldehyde 3‐phosphate‐dehydrogenase gene in HeLa cells
1984
Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: comparison with the other human Cγgenes
1986
Rho family GTPases control entry of Shigella flexneri into epithelial cells but not intracellular motility
1999
Rho and Rac exert antagonistic functions on spreading of macrophage-derived multinucleated cells and are not required for actin fiber formation
2000
Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues
1984
RhoG GTPase Controls a Pathway That Independently Activates Rac1 and Cdc42Hs
1998
Effects of Transition Mutations in the Regulatory Locus spoIIA on the Incidence of Sporulation in Bacillus subtilis
1985
Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family
1985 Standout
Nucleotide Sequence of Sporulation Locus spoIIA in Bacillus subtilis
1984
A warning on the use of synthetic DNA primers for initiation of reverse transcription on RNA templates: unexpected initiation at a mismatched nucleotide
1982