Citation Impact
Citing Papers
Argonaute2 Is the Catalytic Engine of Mammalian RNAi
2004 StandoutScience
Epigenetic Repression of DNA Mismatch Repair by Inflammation and Hypoxia in Inflammatory Bowel Disease–Associated Colorectal Cancer
2009 StandoutNobel
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
2009 StandoutScienceNobel
Experimental models of inflammatory bowel disease
1995 Standout
Two aromatic residues regulate the response of the human oxytocin receptor to the partial agonist arginine vasopressin
1996
Molecular cloning and functional characterization of V2 [8‐lysine] vasopressin and oxytocin receptors from a pig kidney cell line
1993
Molecular neurobiology and pharmacology of the Vasopressin/Oxytocin receptor family
1995
Oxytocin receptors expressed and coupled to Ca2+signalling in a human vascular smooth muscle cell line
1996
EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins
1996 StandoutNobel
The anatomical basis of intestinal immunity
1997
Structural bases of vasopressin/oxytocin receptor function
1998
Two stage genome–wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12
1996
Role for epithelial dysregulation in early-onset colitis-associated colon cancer in Gi2-alpha−/− mice
2008 StandoutNobel
Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota
2005
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
Oncogenic kinase signalling
2001 StandoutNature
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
An extracellular residue determines the agonist specificity of V2 vasopressin receptors
1995
Regulatory T Cells
2000 StandoutNobel
Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses.
1996
Adrenergic Receptors From Molecular Structure to in vivo function
1997 StandoutNobel
A capsaicin-receptor homologue with a high threshold for noxious heat
1999 StandoutNatureNobel
Mouse Models of Colon Cancer
2009
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Layers of mutualism with commensal bacteria protect us from intestinal inflammation
2006
Involvement of chemokine receptors in breast cancer metastasis
2001 StandoutNature
The Binding Site of Neuropeptide Vasopressin V1a Receptor
1995
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
2001 StandoutNature
Protein Kinase A Anchoring Proteins Are Required for Vasopressin-mediated Translocation of Aquaporin-2 into Cell Membranes of Renal Principal Cells
1999
Vasopressin and oxytocin receptors
1996
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
1998 StandoutNature
Transforming growth factor-β induces development of the TH17 lineage
2006 StandoutNature
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
2001 StandoutNature
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
Teleost isotocin receptor: structure, functional expression, mRNA distribution and phylogeny
1995
Renal oxytocin receptor messenger ribonucleic acid: characterization and regulation during pregnancy and in response to ovarian steroid treatment.
1996
Different Single Receptor Domains Determine the Distinct G Protein Coupling Profiles of Members of the Vasopressin Receptor Family
1996
Immunity, Inflammation, and Cancer
2010 Standout
Heterotrimeric G proteins
1996
The drosophila gastrulation gene concertina encodes a Gα-like protein
1991 StandoutNobel
TCR-mediated hyper-responsiveness of autoimmune G i2-/- mice is an intrinsic naive CD4+ T cell disorder selective for the G i2 subunit
2003
trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca2+ Entry
1996
Molecular tinkering of G protein-coupled receptors: an evolutionary success
1999
Origin and physiological roles of inflammation
2008 StandoutNature
The VPAC2 Receptor Is Essential for Circadian Function in the Mouse Suprachiasmatic Nuclei
2002
Cells and Cytokines in the Pathogenesis of Inflammatory Bowel Disease: New Insights from Mouse T Cell Transfer Models
2000
A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice
1999
A microbial symbiosis factor prevents intestinal inflammatory disease
2008 StandoutNature
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
Points of control in inflammation
2002 StandoutNature
Regulatory T cells and inflammatory bowel disease
1999
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
Cloning and Functional Characterization of the Amphibian Mesotocin Receptor, a Member of the Oxytocin/Vasopressin Receptor Superfamily
1996
Coupled oscillators control morning and evening locomotor behaviour of Drosophila
2004 StandoutNatureNobel
Coordination of circadian timing in mammals
2002 StandoutNature
Defective arachidonate release and PGE2 production in Giα2-deficient intestinal and colonic subepithelial myofibroblasts
2006 StandoutNobel
Co-evolution of Ligand-Receptor Pairs in the Vasopressin/Oxytocin Superfamily of Bioactive Peptides
1996
Agonist and Antagonist-Dependent Internalization of the Human Vasopressin V2Receptor
1998
A Case for Regulatory B Cells
2006
Nephrogenic Diabetes Insipidus
2001
Nephrogenic diabetes insipidus. A V2 vasopressin receptor unable to stimulate adenylyl cyclase
1993
Molecular Endocrinology of the Oxytocin Receptor.
1995
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Impaired TGF-β Responses in Peripheral T Cells of Gαi2−/− Mice
2005 StandoutNobel
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
B Cell Developmental Requirement for the Gαi2 Gene
2003
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Newly Identified Brain Potassium Channels Gated by the Guanine Nucleotide Binding Protein G o
1988 Science
Microsomal and cytosolic fractions of guinea pig hepatocytes contain 100-kilodalton GTP-binding proteins reactive with antisera against alpha subunits of stimulatory and inhibitory heterotrimeric GTP-binding proteins.
1990 StandoutNobel
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Octyl glucoside extracts GTP-binding regulatory proteins from rat brain "synaptoneurosomes" as large, polydisperse structures devoid of beta gamma complexes and sensitive to disaggregation by guanine nucleotides.
1990 StandoutNobel
The Oxytocin Receptor
1999
Myocyte Adrenoceptor Signaling Pathways
2003 StandoutScienceNobel
Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.
1994 StandoutNobel
Structure, characterization, and expression of the rat oxytocin receptor gene.
1995
Network of dendritic cells within the muscular layer of the mouse intestine
2005 StandoutNobel
Sequence-specific "gene signatures" can beobtained by PCR with single specific primers at low stringency.
1994
Identification of chemoattractant receptors and G-proteins in the vomeronasal system of garter snakes
1994
Properties of the human arginine vasopressin V2 receptor after site-directed mutagenesis of its putative palmitoylation site
1996
The disaggregation theory of signal transduction revisited: further evidence that G proteins are multimeric and disaggregate to monomers when activated.
1993 StandoutNobel
Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase.
1993
Rat testicular myoid cells express vasopressin receptors: receptor structure, signal transduction, and developmental regulation.
1995
Neuronal expression of a newly identified Drosophila melanogaster G protein alpha 0 subunit.
1989
Expression of the Oxytocin and Vasopressin Genes
1992
A resetting signal between Drosophila pacemakers synchronizes morning and evening activity
2005 StandoutNatureNobel
Homologous and unique G protein alpha subunits in the nematode Caenorhabditis elegans.
1991
Glucagon induces disaggregation of polymer-like structures of the alpha subunit of the stimulatory G protein in liver membranes.
1991 StandoutNobel
Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia
2004
Calcium/Calmodulin-Dependent Protein Kinase II Regulates Caenorhabditis elegans Locomotion in Concert With a Go/Gq Signaling Network
2000
Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor.
1995
Structural organization of the human oxytocin receptor gene.
1994
The Oxytocin Receptor System: Structure, Function, and Regulation
2001 Standout
Heterotrimeric G proteins in synaptoneurosome membranes are crosslinked by p-phenylenedimaleimide, yielding structures comparable in size to crosslinked tubulin and F-actin.
1992 StandoutNobel
Agonist-specific alterations in receptor–phospholipase coupling following inactivation of Gi2α gene
1998
A nuclear 'fossil' of the mitochondrial D-loop and the origin of modern humans
1995 StandoutNatureNobel
Evidence for distinct signaling mechanisms in two mammalian olfactory sense organs.
1996 StandoutNobel
Amino acids 367-376 of the Gs alpha subunit induce membrane association when fused to soluble amino-terminal deleted Gi1 alpha subunit.
1991
Lipid modifications of G proteins: alpha subunits are palmitoylated.
1993 StandoutNobel
Citrobacter rodentiumInfection in Mice Elicits a Mucosal Th1 Cytokine Response and Lesions Similar to Those in Murine Inflammatory Bowel Disease
1999
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
Immunological and Molecular Characterization of Goα-like Proteins in the Drosophila Central Nervous System
1989
Mutational analysis and molecular modeling of the nonapeptide hormone binding domains of the [Arg8]vasotocin receptor.
1996
Transgenic rats reveal functional conservation of regulatory controls between the Fugu isotocin and rat oxytocin genes
1997 StandoutNobel
Carbachol-activated muscarinic (M1 and M3) receptors transfected into Chinese hamster ovary cells inhibit trafficking of endosomes.
1991 StandoutNobel
Works of Philippe Brabet being referenced
Immunological localization of the GTP-binding protein Go in different tissues of vertebrates and invertebrates.
1987
Disruption of the Gi2α locus in embryonic stem cells and mice: a modified hit and run strategy with detection by a PCR dependent on gap repair
1993
Ultrastructural localization of the GTP-binding protein Go in neurons
1989
Alternative Splicing in the N-terminal Extracellular Domain of the Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) Receptor Modulates Receptor Selectivity and Relative Potencies of PACAP-27 and PACAP-38 in Phospholipase C Activation
1996
Molecular cloning of the receptor for human antidiuretic hormone
1992 Nature
Gi2? protein deficiency: A model for inflammatory bowel disease
1995
Ulcerative colitis and adenocarcinoma of the colon in Gαi2-deficient mice
1995
Immunocytochemical localization of the guanine nucleotide-binding protein Go in primary cultures of neuronal and glial cells
1988
Structure and chromosomal localization of the human antidiuretic hormone receptor gene.
1992
Expression of the Opa1 Mitochondrial Protein in Retinal Ganglion Cells: Its Downregulation Causes Aggregation of the Mitochondrial Network
2005
Multiple neurological abnormalities in mice deficient in the G protein G o
1998
Dissociation between Light-Induced Phase Shift of the Circadian Rhythm and Clock Gene Expression in Mice Lacking the Pituitary Adenylate Cyclase Activating Polypeptide Type 1 Receptor
2001
Immunocytochemical localization of the guanine nucleotide-binding protein Go in primary cultures of neuronal and glial cells.
1988
Apical localization of the alpha subunit of GTP-binding protein Go in choroidal and ciliated ependymocytes [published erratum appears in J Neurosci 1989 Apr;9(4):following Table of Contents]
1989