Citation Impact
Citing Papers
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
2011 Standout
Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
2010 StandoutScience
GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models
2008 Standout
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
GPCR activation mechanisms across classes and macro/microscales
2021
G Protein-coupled Receptor Kinase and β-Arrestin-mediated Desensitization of the Angiotensin II Type 1A Receptor Elucidated by Diacylglycerol Dynamics
2006 StandoutNobel
Dopaminergic signaling in dendritic spines
2008
Nanobody stabilization of G protein-coupled receptor conformational states
2011 StandoutNobel
Synthesis of Monodisperse Spherical Nanocrystals
2007 Standout
β-Arrestin-biased Agonism at the β2-Adrenergic Receptor
2007 StandoutNobel
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
2006 StandoutNobel
Dynamics of receptor/G protein coupling in living cells
2005
Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer
2009 StandoutNobel
Ligand-Specific Interactions Modulate Kinetic, Energetic, and Mechanical Properties of the Human β2 Adrenergic Receptor
2012 StandoutNobel
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease
2010
Quantifying Ligand Bias at Seven-Transmembrane Receptors
2011 StandoutNobel
New Concepts in Drug Discovery: Collateral Efficacy and Permissive Antagonism
2005
Genetically Encodable Fluorescent Biosensors for Tracking Signaling Dynamics in Living Cells
2011
Differential Signaling of the Endogenous Agonists at the β2-Adrenergic Receptor
2010
Molecular Dynamics Simulation for All
2018 Standout
Structural basis of function in heterotrimeric G proteins
2006
Dopamine receptor-interacting proteins: the Ca2+ connection in dopamine signaling
2003
Characterization of the expression and regulation of MK5 in the murine ventricular myocardium
2010
Applications of bioluminescence- and fluorescence resonance energy transfer to drug discovery at G protein-coupled receptors
2004
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
2010 StandoutNatureNobel
Kinetic Analysis of G Protein–Coupled Receptor Signaling Using Fluorescence Resonance Energy Transfer in Living Cells
2007
Therapeutic potential of β-arrestin- and G protein-biased agonists
2010 StandoutNobel
Role of Detergents in Conformational Exchange of a G Protein-coupled Receptor
2012 StandoutNobel
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Bioluminescence Resonance Energy Transfer Assays Reveal Ligand-specific Conformational Changes within Preformed Signaling Complexes Containing δ-Opioid Receptors and Heterotrimeric G Proteins
2008
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
The Physiology, Signaling, and Pharmacology of Dopamine Receptors
2011 Standout
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
Photoactivable peptides for identifying enzyme–substrate and protein–protein interactions
2010 StandoutNobel
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling
2011 StandoutNobel
Characterization of a novel MK3 splice variant from murine ventricular myocardium
2010
The dopamine D4 receptor: biochemical and signalling properties
2010
Core/Shell Semiconductor Nanocrystals
2009 Standout
Multiple ligand-specific conformations of the β2-adrenergic receptor
2011 StandoutNobel
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
2011 StandoutNatureNobel
Calmodulin Suppresses Synaptotagmin-2 Transcription in Cortical Neurons*
2010 StandoutNobel
Teaching old receptors new tricks: biasing seven-transmembrane receptors
2010 StandoutNobel
Pharmacology and Signaling Properties of Epidermal Growth Factor Receptor Isoforms Studied by Bioluminescence Resonance Energy Transfer
2006
Real-time optical recording of β1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol
2007
Stimulation of cannabinoid (CB1) and prostanoid (EP2) receptors opens BKCa channels and relaxes ocular trabecular meshwork
2005
Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy
2017 Standout
Cell‐based assays in GPCR drug discovery
2008
Functional Selectivity of Natural and Synthetic Prostaglandin EP4 Receptor Ligands
2009
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Structural insights into adrenergic receptor function and pharmacology
2011 StandoutNobel
Heterotrimeric G protein activation by G-protein-coupled receptors
2007
Dopamine Receptor Signaling
2004
Supramolecular Assemblies and Localized Regulation of Voltage-Gated Ion Channels
2009
Dopamine in Motivational Control: Rewarding, Aversive, and Alerting
2010 Standout
A FlAsH-based FRET approach to determine G protein–coupled receptor activation in living cells
2005 StandoutNobel
Morphine-like Opiates Selectively Antagonize Receptor-Arrestin Interactions
2010
Techniques: Promiscuous Gα proteins in basic research and drug discovery
2005
Molecular Basis for G Protein Control of the Prokaryotic ATP Sulfurylase
2006 StandoutNobel
Conformational Rearrangements and Signaling Cascades Involved in Ligand-Biased Mitogen-Activated Protein Kinase Signaling through the β1-Adrenergic Receptor
2008
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Recovery of Oligomers and Cooperativity When Monomers of the M2Muscarinic Cholinergic Receptor Are Reconstituted into Phospholipid Vesicles
2007
G Protein Signaling: Insights from New Structures
2004
Distinct profiles of functional discrimination among G proteins determine the actions of G protein–coupled receptors
2015
Elucidating the Mechanism of Cellular Uptake and Removal of Protein-Coated Gold Nanoparticles of Different Sizes and Shapes
2007 Standout
CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
2009
Dopamine Receptor-interacting Protein 78 Acts as a Molecular Chaperone for Gγ Subunits before Assembly with Gβ
2007
Interactive Proteomics: What Lies Ahead?
2008
Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks
2018
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
Functional Nanomaterials for Phototherapies of Cancer
2014 Standout
Chaperone-Assisted Protein Folding Is Critical for Yellow Fever Virus NS3/4A Cleavage and Replication
2016 StandoutNobel
Complexes between photoactivated rhodopsin and transducin: progress and questions
2010
The evasive nature of drug efficacy: implications for drug discovery
2007
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells
2005
β-Arrestin-biased ligands at seven-transmembrane receptors
2007 StandoutNobel
Molecular Determinants of Selectivity and Efficacy at the Dopamine D3 Receptor
2012
Quantum Dots in Biological and Biomedical Research: Recent Progress and Present Challenges
2006
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
2009 StandoutNobel
Inorganic Nanoparticles for MRI Contrast Agents
2009 Standout
Works of Phan Trieu being referenced
Real-time monitoring of receptor and G-protein interactions in living cells
2005
G Protein-coupled Receptors Form Stable Complexes with Inwardly Rectifying Potassium Channels and Adenylyl Cyclase
2002
Functional β-adrenergic receptor signalling on nuclear membranes in adult rat and mouse ventricular cardiomyocytes
2006
Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells
2006