Citation Impact
Citing Papers
Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
2000 StandoutScience
Basal cell carcinomas: attack of the hedgehog
2008 Standout
Structure–activity relationships of piperazinebenzylamines as potent and selective agonists of the human melanocortin-4 receptor
2004
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines
2007 Standout
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
2004 Standout
Anatomy and regulation of the central melanocortin system
2005 Standout
Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens
2006 Standout
Cytochrome P450: taming a wild type enzyme
2011 StandoutNobel
Melanocortin receptor signaling in RAW264.7 macrophage cell line
2005
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
MC4R Agonists: Structural Overview on Antiobesity Therapeutics
2018 StandoutNobel
Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models
2016 StandoutNobel
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
2001 StandoutNature
Melanocortin Signalling Mechanisms
2010
Receptor systems: Will mining the receptorome yield novel targets for pharmacotherapy?
2005
Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring
2013
Alignment-free sequence comparison—a review
2003
Physiology and immunology of the cholinergic antiinflammatory pathway
2007 Standout
Type I β‐turn conformation is important for biological activity of the melanocyte‐stimulating hormone analogues
1999
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Autoantibodies against appetite-regulating peptide hormones and neuropeptides: Putative modulation by gut microflora
2008
Subcutaneous fat in normal and diseased states
2005
Strategies for development of dengue virus inhibitors
2010
α-Melanotropin hormone inhibits the binding of []SCH 23390 to the dopamine D1 receptor in vitro
1998
Subcutaneous fat in normal and diseased states
2007
The Melanocortin 4 Receptor Mediates Leptin Stimulation of Luteinizing Hormone and Prolactin Surges in Steroid-Primed Ovariectomized Rats
1999
Functional Characterization of cis and trans Activity of the Flavivirus NS2B-NS3 Protease
2007
Melanocortins and their implication in melanoma
1995
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
The melanocortin receptors and their accessory proteins
2013
Adrenocorticotropin reverses hemorrhagic shock in anesthetized rats through the rapid activation of a vagal anti-inflammatory pathway
2004
Effects of melanocortin peptides on lipopolysaccharide/interferon-gamma-induced NF-kappaB DNA binding and nitric oxide production in macrophage-like RAW 264.7 cells:
2001
A role for MC3R in modulating lung inflammation
2008
Genetic disruption of γ-melanocyte–stimulating hormone signaling leads to salt-sensitive hypertension in the mouse
2003
Probing the substrate specificities of matriptase, matriptase‐2, hepsin and DESC1 with internally quenched fluorescent peptides
2009
β-Alanine dipeptides as MC4R agonists
2003
Contribution of Melanocortin Receptor Exoloops to Agouti-related Protein Binding
1999
The Chemical Information Ontology: Provenance and Disambiguation for Chemical Data on the Biological Semantic Web
2011
Gout
2016 Standout
Combined biophysical and biochemical information confirms arrangement of transmembrane helices visible from the three-dimensional map of frog rhodopsin
1998
The nervous system and innate immunity: the neuropeptide connection
2005
Extensive structure–activity studies of lactam derivatives of MT‐II and SHU‐9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5
2003
The role of proopiomelanocortin (POMC) neurones in feeding behaviour
2007
Structure–Activity relationship of linear peptide Bu-His6-DPhe7-Arg8-Trp9-Gly10-NH2 at the human melanocortin-1 and -4 receptors: DPhe7 and Trp9 substitution
2003
Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study
2012 StandoutNobel
The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene
1999 Standout
Regulatory T cells in transplantation tolerance
2003 StandoutNobel
Melanocortin Receptors and Erectile Function
2004
Melanocortin control of energy balance: evidence from rodent models
2011
“The role of melanocortins in body weight regulation: opportunities for the treatment of obesity”
2002
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins
2012 StandoutNobel
Characterization of melanocortin receptor ligands on cloned brain melanocortin receptors and on grooming behavior in the rat
1999
The MC4 receptor mediates α-MSH induced release of nucleus accumbens dopamine
2001
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Structure-Activity Relationships (SAR) of Melanocortin and Agouti-Related (AGRP) Peptides
2010
Cardiovascular effects of melanocortins
2011
Seven-transmembrane receptors
2002 StandoutNobel
Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis
2002
Evaluation of the safety, pharmacokinetics and pharmacodynamic effects of subcutaneously administered PT-141, a melanocortin receptor agonist, in healthy male subjects and in patients with an inadequate response to Viagra®
2004
Structure, function and regulation of the melanocortin receptors
2011
Determining membrane protein structures: still a challenge!
2007
Exploring the full spectrum of macrophage activation
2008 Standout
Analogs of Lactam Derivatives of α-Melanotropin with Basic and Acidic Residues
2000
Melanocortin-1 Receptor Gene Variants Determine the Risk of Nonmelanoma Skin Cancer Independently of Fair Skin and Red Hair
2001
Piperazinebenzylamines as potent and selective antagonists of the human melanocortin-4 receptor
2004
Adipose Tissue as an Endocrine Organ
2004 Standout
PREDICT modeling and in‐silico screening for G‐protein coupled receptors
2004
Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins
2010 StandoutNobel
Conformation of the Core Sequence in Melanocortin Peptides Directs Selectivity for the Melanocortin MC3 and MC4 Receptors
1999
Synthesis of novel melanocortin 4 receptor agonists and antagonists containing a succinamide core
2003
Conformational Plasticity and Structure/Function Relationships in Cytochromes P450
2010
Toward high-resolution prediction and design of transmembrane helical protein structures
2007 StandoutNobel
Scanning Mutagenesis Studies of the M 1 Muscarinic Acetylcholine Receptor
2003
Regulation of Thyrotropin-Releasing Hormone-Expressing Neurons in Paraventricular Nucleus of the Hypothalamus by Signals of Adiposity
2010
Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight*
1999
Gut Microbiota in Health and Disease
2010 Standout
Chemistry of Polyvalent Iodine
2008 Standout
Human evolution
1999 StandoutNobel
Utility of Humanized BLT Mice for Analysis of Dengue Virus Infection and Antiviral Drug Testing
2013 StandoutNobel
Identification of Tetrapeptides from a Mixture Based Positional Scanning Library That Can Restore nM Full Agonist Function of the L106P, I69T, I102S, A219V, C271Y, and C271R Human Melanocortin-4 Polymorphic Receptors (hMC4Rs)
2014
Structure−Activity Relationships of the Melanocortin Tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 at the Mouse Melanocortin Receptors. 1. Modifications at the His Position
2002
Preparation of Alkyl Carbamate of 1‐Protected Indole‐3‐methylamine as a Precursor of Indole‐3‐methylamine
2005
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro
2012 StandoutNobel
Characterization of Melanocortin NDP-MSH Agonist Peptide Fragments at the Mouse Central and Peripheral Melanocortin Receptors
2001
The Organocatalytic Approach to Enantiopure 2H‐ and 3H‐Pyrroles: Inhibitors of the Hedgehog Signaling Pathway
2016 StandoutNobel
In vitro induction of CD25+ CD4+ regulatory T cells by the neuropeptide alpha‐melanocyte stimulating hormone (α‐MSH)
2001
Bremelanotide for Female Sexual Dysfunctions in Premenopausal Women: A Randomized, Placebo-Controlled Dose-Finding Trial
2016
High Polymorphism at the Human Melanocortin 1 Receptor Locus
1999
Effects of Chronic Central Nervous System Administration of Agouti-Related Protein in Pair-Fed Animals
2001
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
Tandem Facial Amphiphiles for Membrane Protein Stabilization
2010 StandoutNobel
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
2011 Standout
Selective, High Affinity Peptide Antagonists of α-Melanotropin Action at Human Melanocortin Receptor 4: Their Synthesis and Biological Evaluation in Vitro
2001
PubChem 2023 update
2022 Standout
Structure−Activity Studies of the Melanocortin Peptides: Discovery of Potent and Selective Affinity Antagonists for thehMC3 andhMC4 Receptors
2002
Thyroid Hormone Regulation of Metabolism
2014 Standout
Subcutaneous and Visceral Adipose Tissue: Their Relation to the Metabolic Syndrome
2000 Standout
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
Computational Modeling Approaches to Structure−Function Analysis of G Protein-Coupled Receptors
2005
Click-Chemistry-Mediated Synthesis of Selective Melanocortin Receptor 4 Agonists
2017 StandoutNobel
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Dimerization of G-Protein-Coupled Receptors
2001
The Melanocortin-4 Receptor: Physiology, Pharmacology, and Pathophysiology
2010
Genetic disruption of γ-melanocyte–stimulating hormone signaling leads to salt-sensitive hypertension in the mouse
2003
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
A Solid-Phase Approach to Mouse Melanocortin Receptor Agonists Derived from a Novel Thioether Cyclized Peptidomimetic Scaffold
2002 StandoutNobel
Structure−Activity Relationships of the Melanocortin Tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 at the Mouse Melanocortin Receptors: Part 2 Modifications at the Phe Position
2002
Human evolution
1999 StandoutNobel
Clinical, Genetic, and Functional Characterization of Adrenocorticotropin Receptor Mutations Using a Novel Receptor Assay
2002
Interactions of Human Melanocortin 4 Receptor with Nonpeptide and Peptide Agonists,
2005
Gut hormone PYY3-36 physiologically inhibits food intake
2002 StandoutNature
Differentiation of Effector CD4 T Cell Populations
2010 Standout
Interactions Between the Melanocortin System and Leptin in Control of Sympathetic Nerve Traffic
1999
Machine learning methods in chemoinformatics
2014
Corticotropin Releasing Hormone and Proopiomelanocortin Involvement in the Cutaneous Response to Stress
2000
γ-MSH, sodium metabolism, and salt-sensitive hypertension
2004
Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450
2015 StandoutNobel
Works of Peteris Prūsis being referenced
Prediction of indirect interactions in proteins
2006
Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling
2005
Evaluation of the human prediction of clearance from hepatocyte and microsome intrinsic clearance for 52 drug compounds
2010
Discovery of novel melanocortin4 receptor selective MSH analogues
1998
A Look Inside HIV Resistance through Retroviral Protease Interaction Maps
2007
A Three-Dimensional Model for the Interaction of MSH with the Melanocortin-1 Receptor
1995
Rough set‐based proteochemometrics modeling of G‐protein‐coupled receptor‐ligand interactions
2006
Classification of G‐protein coupled receptors by alignment‐independent extraction of principal chemical properties of primary amino acid sequences
2002
Characterisation of D117A and H260A mutations in the melanocortin 1 receptor
1997
New aspects on the melanocortins and their receptors
2000
Proteochemometrics analysis of substrate interactions with dengue virus NS3 proteases
2008
Evidence Indicating That the TM4, EL2, and TM5 of the Melanocortin 3 Receptor Do Not Participate in Ligand Binding
1996
Binding of cyclic and linear MSH core peptides to the melanocortin receptor subtypes
1997
Evidence for Alternate Points of Attachment for α-MSH and Its Stereoisomer (Nle4,D-Phe7)-α-MSH at the Melanocortin-1 Receptor
1994
PLS modeling of chimeric MS04/MSH-peptide and MC1/MC3-receptor interactions reveals a novel method for the analysis of ligand–receptor interactions
2001
Design of new small cyclic melanocortin receptor-binding peptides using molecular modelling: Role of the His residue in the melanocortin peptide core
2001
Long term orexigenic effect of a novel melanocortin 4 receptor selective antagonist
1999
Modeling of the three-dimensional structure of the human melanocortin 1 receptor, using an automated method and docking of a rigid cyclic melanocyte-stimulating hormone core peptide
1997
Improvement of Site of Metabolism Predictions for CYP3A4 by Using Discriminant Analysis of Compound Preference of CYP3A4 X‐Ray Structural Conformers and Subsequent Docking
2009
QSAR and Proteo-chemometric Analysis of the Interaction of a Series of Organic Compounds with Melanocortin Receptor Subtypes
2003
Proteochemometrics Modeling of the Interaction of Amine G-Protein Coupled Receptors with a Diverse Set of Ligands
2002
Selectivity of Cyclic [d-Nal7] and [d-Phe7] Substituted MSH Analogues for the Melanocortin Receptor Subtypes
1997
Selective properties of C- and N-terminals and core residues of the melanocyte-stimulating hormone on binding to the human melanocortin receptor subtypes
1998
Probing the substrate specificity of the dengue virus type 2 NS3 serine protease by using internally quenched fluorescent peptides
2006