Citation Impact
Citing Papers
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
2009
Single-Molecule Imaging of an in Vitro -Evolved RNA Aptamer Reveals Homogeneous Ligand Binding Kinetics
2009 StandoutNobel
Elongation Factor G Bound to the Ribosome in an Intermediate State of Translocation
2013 ScienceNobel
Spatially resolved, highly multiplexed RNA profiling in single cells
2015 StandoutScience
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
Control of Ribosomal Subunit Rotation by Elongation Factor G
2013 Science
Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70 S Ribosome
2009 StandoutScienceNobel
Activation of MDA5 Requires Higher-Order RNA Structures Generated during Virus Infection
2009
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Structure of the ribosome with elongation factor G trapped in the pretranslocation state
2013
Crystal Structures of EF-G–Ribosome Complexes Trapped in Intermediate States of Translocation
2013 Science
LGP2 is a positive regulator of RIG-I– and MDA5-mediated antiviral responses
2010
Direct single-molecule observation of a protein living in two opposed native structures
2009
The Ribosome as a Conveying Thermal Ratchet Machine
2009
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Reinitiation and Other Unconventional Posttermination Events during Eukaryotic Translation
2013
A structural view on the mechanism of the ribosome-catalyzed peptide bond formation
2009 StandoutNobel
The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells
2011
PcrA Helicase Dismantles RecA Filaments by Reeling in DNA in Uniform Steps
2010
mRNA translocation occurs during the second step of ribosomal intersubunit rotation
2011
EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics
2014 StandoutNobel
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Rethinking amide bond synthesis
2011 StandoutNature
An Oxygen Scavenging System for Improvement of Dye Stability in Single-Molecule Fluorescence Experiments
2007
Watching conformational- and photodynamics of single fluorescent proteins in solution
2010 StandoutNobel
Continuous changes in structure mapped by manifold embedding of single-particle data in cryo-EM
2016 StandoutNobel
Contribution of intersubunit bridges to the energy barrier of ribosomal translocation
2012
Pattern Recognition Receptors and Inflammation
2010 Standout
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
The Cryo-EM Structure of a Complete 30S Translation Initiation Complex from Escherichia coli
2011
Whither Ribosome Structure and Dynamics Research? (A Perspective)
2016 StandoutNobel
Biological mechanisms, one molecule at a time
2011
A fast dynamic mode of the EF‐G‐bound ribosome
2009
Molecular dynamics of EF‐G during translocation
2011 StandoutNobel
Two promising future developments of cryo-EM: capturing short-lived states and mapping a continuum of states of a macromolecule
2015 StandoutNobel
Intersubunit Bridges of the Bacterial Ribosome
2016
Structural insights into cognate versus near‐cognate discrimination during decoding
2011 StandoutNobel
RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection
2010
Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy
2010 Nature
Intermediate states during mRNA–tRNA translocation
2012 StandoutNobel
Structure and Dynamics of the Mammalian Ribosomal Pretranslocation Complex
2011
Structure of the mammalian ribosomal pre-termination complex associated with eRF1•eRF3•GDPNP
2013 StandoutNobel
Allosteric control of the ribosome by small-molecule antibiotics
2012
Structural dynamics of the ribosome
2008
Navigating the ribosome's metastable energy landscape
2009
Single-Molecule Study of Ribosome Hierarchic Dynamics at the Peptidyl Transferase Center
2010
Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome
2015
Ribosome-targeting antibiotics and mechanisms of bacterial resistance
2013
Cardiac glycosides are potent inhibitors of interferon-β gene expression
2010
Single-Molecule Fluorescence Measurements of Ribosomal Translocation Dynamics
2011
Empirical Bayes Methods Enable Advanced Population-Level Analyses of Single-Molecule FRET Experiments
2014
Focus on function: Single molecule RNA enzymology
2007
Visualization of the Hybrid State of tRNA Binding Promoted by Spontaneous Ratcheting of the Ribosome
2008 StandoutNobel
Structure of the Human Telomerase RNA Pseudoknot Reveals Conserved Tertiary Interactions Essential for Function
2005
Structural basis of RNA recognition and activation by innate immune receptor RIG-I
2011 Nature
Energy barriers and driving forces in tRNA translocation through the ribosome
2013
Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation
2015
Transfer RNA–mediated regulation of ribosome dynamics during protein synthesis
2011
Classification of Structural Heterogeneity by Maximum-Likelihood Methods
2010
Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation
2016
A microfluidic approach for investigating the temperature dependence of biomolecular activity with single-molecule resolution
2010
Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu
2009 StandoutNobel
Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation
2015 Nobel
Srs2 prevents Rad51 filament formation by repetitive motion on DNA
2013
Using Molecular Simulation to Model High-Resolution Cryo-EM Reconstructions
2015
Correlated conformational events in EF-G and the ribosome regulate translocation
2010
Learning Rates and States from Biophysical Time Series: A Bayesian Approach to Model Selection and Single-Molecule FRET Data
2009
Antibacterial drug discovery in the resistance era
2016 StandoutNature
Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System
2015 StandoutNobel
Unraveling the dynamics of ribosome translocation
2012
Coordinated conformational and compositional dynamics drive ribosome translocation
2013
Structure of the human 80S ribosome
2015 Nature
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
RNA helicases at work: binding and rearranging
2010
Connecting the Kinetics and Energy Landscape of tRNA Translocation on the Ribosome
2013
ATP-Dependent Effector-like Functions of RIG-I-like Receptors
2015 StandoutNobel
Structural Dynamics of Ribosome Subunit Association Studied by Mixing-Spraying Time-Resolved Cryogenic Electron Microscopy
2015 StandoutNobel
Structure and Dynamics of a Processive Brownian Motor: The Translating Ribosome
2010 StandoutNobel
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
Rotation of the head of the 30S ribosomal subunit during mRNA translocation
2012
Structures of the Ribosome in Intermediate States of Ratcheting
2009 Science
Structural Insight into Nascent Polypeptide Chain–Mediated Translational Stalling
2009 StandoutScienceNobel
Structural characterization of mRNA-tRNA translocation intermediates
2012 StandoutNobel
Converting structural information into an allosteric-energy-based picture for elongation factor Tu activation by the ribosome
2011 StandoutNobel
Structures of the Bacterial Ribosome in Classical and Hybrid States of tRNA Binding
2011 Science
Spontaneous formation of the unlocked state of the ribosome is a multistep process
2009
The Molecular Interactions That Stabilize RNA Tertiary Structure: RNA Motifs, Patterns, and Networks
2011
Quantitative Connection between Ensemble Thermodynamics and Single-Molecule Kinetics: A Case Study Using Cryogenic Electron Microscopy and Single-Molecule Fluorescence Resonance Energy Transfer Investigations of the Ribosome
2015 StandoutNobel
Structural insights into ribosome translocation
2016
Ribosomal Translocation: One Step Closer to the Molecular Mechanism
2009
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
Sensing cooperativity in ATP hydrolysis for single multisubunit enzymes in solution
2011 StandoutNobel
Electrostatic origin of the mechanochemical rotary mechanism and the catalytic dwell of F1-ATPase
2011 StandoutNobel
STED nanoscopy combined with optical tweezers reveals protein dynamics on densely covered DNA
2013 StandoutNobel
Trajectories of the ribosome as a Brownian nanomachine
2014 StandoutNobel
RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila
2010 StandoutNobel
Nanostructured Plasmonic Sensors
2008 Standout
The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State
2009 StandoutScienceNobel
Irreversible chemical steps control intersubunit dynamics during translation
2008
RNA Scanning of a Molecular Machine with a Built-in Ruler
2016 StandoutNobel
Single-molecule spectroscopy reveals photosynthetic LH2 complexes switch between emissive states
2013 StandoutNobel
Structure of ratcheted ribosomes with tRNAs in hybrid states
2008
Molecular Machines in Biology
2011 StandoutNobel
The ribosome as a molecular machine: the mechanism of tRNA–mRNA movement in translocation
2011
The ribosome uses cooperative conformational changes to maximize and regulate the efficiency of translation
2014
Functional analysis of the pseudoknot structure in human telomerase RNA
2005 StandoutNobel
Influence of Constitution and Charge on Radical Pairing Interactions in Tris-radical Tricationic Complexes
2016 StandoutNobel
Redox cycling and kinetic analysis of single molecules of solution-phase nitrite reductase
2011 StandoutNobel
Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation
2011 StandoutNobel
The translation elongation cycle—capturing multiple states by cryo-electron microscopy
2017 StandoutNobel
Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit
2016 StandoutNobel
Quantitative Characterization of Domain Motions in Molecular Machines
2017 StandoutNobel
Acidification of the Oxygen Scavenging System in Single-Molecule Fluorescence Studies: In Situ Sensing with a Ratiometric Dual-Emission Probe
2010
Simulating the pulling of stalled elongated peptide from the ribosome by the translocon
2013 StandoutNobel
Molecular mechanics of 30S subunit head rotation
2014
ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA
2015
Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation
2009
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Peter V. Cornish being referenced
Antibiotics that bind to the A site of the large ribosomal subunit can induce mRNA translocation
2012
Frameshifting RNA pseudoknots: Structure and mechanism
2008
Spontaneous Intersubunit Rotation in Single Ribosomes
2008
The Role of L1 Stalk–tRNA Interaction in the Ribosome Elongation Cycle
2010
Structured m RNA induces the ribosome into a hyper‐rotated state
2014
A Survey of Single-Molecule Techniques in Chemical Biology
2007
Thermodynamic Analysis of Conserved Loop−Stem Interactions in P1−P2 Frameshifting RNA Pseudoknots from Plant Luteoviridae
2002
Cytosolic Viral Sensor RIG-I Is a 5'-Triphosphate–Dependent Translocase on Double-Stranded RNA
2009 Science
Following movement of the L1 stalk between three functional states in single ribosomes
2009
Following Movement of the L1 Stalk between Three Functional States in Single Ribosomes
2010