Citation Impact
Citing Papers
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
2008 Standout
A Unique Structure for Epidermal Growth Factor Receptor Bound to GW572016 (Lapatinib)
2004
Blockade of EGFR and ErbB2 by the Novel Dual EGFR and ErbB2 Tyrosine Kinase Inhibitor GW572016 Sensitizes Human Colon Carcinoma GEO Cells to Apoptosis
2006
Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis
2009 Standout
Optimization and SAR for dual ErbB-1/ErbB-2 tyrosine kinase inhibition in the 6-furanylquinazoline series
2006
Cancer–stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis
2012 StandoutNobel
Systemic Targeting of CpG-ODN to the Tumor Microenvironment with Anti–neu-CpG Hybrid Molecule and T Regulatory Cell Depletion Induces Memory Responses in BALB-neuT Tolerant Mice
2008 StandoutNobel
Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways
2002
Localized cell stimulation by nitric oxide using a photoactive porous coordination polymer platform
2013 StandoutNobel
Optimization of 6,7-Disubstituted-4-(arylamino)quinoline-3-carbonitriles as Orally Active, Irreversible Inhibitors of Human Epidermal Growth Factor Receptor-2 Kinase Activity
2005
Lapatinib plus Capecitabine for HER2-Positive Advanced Breast Cancer
2006 Standout
The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo.
2001
Study of the Biologic Effects of Lapatinib, a Reversible Inhibitor of ErbB1 and ErbB2 Tyrosine Kinases, on Tumor Growth and Survival Pathways in Patients With Advanced Malignancies
2005
A prospective study on the natural course of low‐grade squamous intraepithelial lesions and the presence of HPV16 E2‐, E6‐ and E7‐specific T‐cell responses
2009
p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells
1998
The challenge and prospect of mRNA therapeutics landscape
2020
Materials engineering for immunomodulation
2009 Nature
Targeting hypoxia in cancer therapy
2011 Standout
Nitric oxide synthases: regulation and function
2011 Standout
Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release
2014
Therapy for genital human papillomavirus-related disease
2005
Lack of inducible nitric oxide synthase promotes intestinal tumorigenesis in the ApcMin/+ mouse
2001
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Free radicals, metals and antioxidants in oxidative stress-induced cancer
2006 Standout
The pharmacokinetics of Toll-like receptor agonists and the impact on the immune system
2011
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
2012 Standout
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
2015 Standout
Smoldering and polarized inflammation in the initiation and promotion of malignant disease
2005 Standout
Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success
2012
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
EGF–ERBB signalling: towards the systems level
2006 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Biochemical and MALDI Analysis of the Human Sperm Antigen gp20, Homologue of Leukocyte CD52
1999
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
Chronic antioxidant enzyme mimetic treatment differentially modulates hyperthermia-induced liver HSP70 expression with aging
2005
Delivery technologies for cancer immunotherapy
2019 Standout
Role of nitric oxide in tumour progression: Lessons from human tumours
1998
Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors
2002
Role of nitric oxide in wound healing
2000
Nitric oxide synthases: structure, function and inhibition
2001 Standout
Inflammation and Colon Cancer
2010 Standout
Imiquimod: mode of action
2007
Elimination of large tumors in mice by mRNA-encoded bispecific antibodies
2017 StandoutNobel
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Design of isoform-selective inhibitors of nitric oxide synthase
1998
Kinomics—structural biology and chemogenomics of kinase inhibitors and targets
2003
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
2004 Standout
The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
2010 Standout
Principles of Translational Control: An Overview
2012
Introduction to current and future protein therapeutics: A protein engineering perspective
2011
Regulation of HIF-1α Stability through S-Nitrosylation
2007
A thermostable Cas9 with increased lifetime in human plasma
2017 StandoutNobel
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Glioma Stem Cell Proliferation and Tumor Growth Are Promoted by Nitric Oxide Synthase-2
2011
Relating protein pharmacology by ligand chemistry
2007 Standout
Developing mRNA-vaccine technologies
2012
Design of next-generation protein therapeutics
2010
Comprehensive analysis of kinase inhibitor selectivity
2011 Standout
Nuclear factor-κB
2004 Standout
Biomolecular coronas provide the biological identity of nanosized materials
2012 Standout
The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells
2008 StandoutNobel
Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29
1995
Allergic Airway Hyperresponsiveness and Eosinophil Infiltration is Reduced by a Selective iNOS Inhibitor, 1400W, in Mice
2000
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
2000 Standout
Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
2006 Standout
The role of nitric oxide in tumour progression
2006
17β-Oestradiol treatment modulates nitric oxide synthase activity in MDA231 tumour with implications on growth and radiation response
2002
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Induction of haem oxygenase-1 by nitric oxide and ischaemia in experimental solid tumours and implications for tumour growth
1999
Inhibition of Papillomavirus Protein Function in Cervical Cancer Cells by Intrabody Targeting
2005 StandoutNobel
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Activation of Innate Immunity, Inflammation, and Potentiation of DNA Vaccination through Mammalian Expression of the TLR5 Agonist Flagellin
2005
New Approaches to Immunotherapy for HPV Associated Cancers
2011
Chemoselective Ligation Applied to the Synthesis of a Biantennary N-Linked Glycoform of CD52
2003 StandoutNobel
Nitric oxide and the immune response
2001 Standout
Strategies for extended serum half-life of protein therapeutics
2011
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
The TLR-7 Agonist, Imiquimod, Enhances Dendritic Cell Survival and Promotes Tumor Antigen-Specific T Cell Priming: Relation to Central Nervous System Antitumor Immunity
2006
Human Papillomavirus and Cervical Cancer
2003 Standout
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
2000 Standout
Suppression of intestinal polyposis in Apc(Min/+) mice by inhibiting nitric oxide production.
2001
Regulation of Murine Intestinal Inflammation by Reactive Metabolites of Oxygen and Nitrogen
2001
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
2023 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Recombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyond
2015
Nanobodies: Natural Single-Domain Antibodies
2013 Standout
Nitric oxide in gastrointestinal epithelial cell carcinogenesis: linking inflammation to oncogenesis
2001
Works of Peter Topley being referenced
Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and c-erbB-2
2001
Anti-serum albumin domain antibodies in the development of highly potent, efficacious and long-acting interferon
2010
Imiquimod and resiquimod in a mouse model: adjuvants for DNA vaccination by particle-mediated immunotherapeutic delivery
2004
A novel cell-based assay for the evaluation of anti-ras compounds
1993
Therapeutic immunisation with COPV early genes by epithelial DNA delivery
2003
An element within the 5′ untranslated region of human Hsp70 mRNA which acts as a general enhancer of mRNA translation
2001
Recognition of CD52 allelic gene products by CAMPATH‐1H antibodies
1996
Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor.
1997