Citation Impact
Citing Papers
S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction
2015 Science
Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways
2011
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
Effects of Antibiotics and a Proto-Oncogene Homolog on Destruction of Protein Translocator SecY
2009 Science
VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data
2020 StandoutNobel
Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury
2016
Autophagy in Neurodegenerative Diseases: From Mechanism to Therapeutic Approach
2015
Improved metagenomic analysis with Kraken 2
2019 Standout
Protein misfolding disorders and macroautophagy
2010
Potential for therapeutic manipulation of the UPR in disease
2013
A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function
2011
TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis
2012
PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response
2013
Unfolded Protein Response Signaling and Metabolic Diseases
2013
Activation of the unfolded protein response enhances motor recovery after spinal cord injury
2012
BAX inhibitor‐1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response
2011
The Unfolded Protein Response and Cell Fate Control
2017
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
Endoplasmic reticulum stress, obesity and diabetes
2011
The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration
2019 StandoutNobel
Hepatic Bax Inhibitor-1 Inhibits IRE1α and Protects from Obesity-associated Insulin Resistance and Glucose Intolerance
2009
Direct Association of Unfolded Proteins with Mammalian ER Stress Sensor, IRE1β
2012
A flagellum-specific chaperone facilitates assembly of the core type III export apparatus of the bacterial flagellum
2017 StandoutNobel
Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
2013
Inflammatory links between obesity and metabolic disease
2011 Standout
Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesis
2010
Mechanism and medical implications of mammalian autophagy
2018 Standout
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Autophagic pathways and metabolic stress
2010
Autophagy and the Integrated Stress Response
2010 Standout
The role of autophagy in neurodegenerative disease
2013 Standout
Mfn2 modulates the UPR and mitochondrial function via repression of PERK
2013
Fighting neurodegeneration with rapamycin: mechanistic insights
2011
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
2012 Standout
Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis
2012
Treatment of Obesity with Celastrol
2015 Standout
The endoplasmic reticulum stress response in aging and age-related diseases
2012
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
2014 Standout
Modulating stress responses by the UPRosome: A matter of life and death
2011
TMBIM protein family: ancestral regulators of cell death
2014
Regulation of axon regeneration by the RNA repair and splicing pathway
2015
ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology
2009
Autophagy: Renovation of Cells and Tissues
2011 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1α-XBP1 Signaling through a Physical Interaction
2010
Decoding ALS: from genes to mechanism
2016 StandoutNature
Gene Therapy Strategies to Restore ER Proteostasis in Disease
2018
Nonmuscle Myosin IIB Links Cytoskeleton to IRE1α Signaling during ER Stress
2012
Endoplasmic reticulum stress-sensing mechanisms in yeast and mammalian cells
2010
The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum
2019
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Dynamics and functions of lipid droplets
2018 Standout
Autophagy in Human Health and Disease
2013 Standout
Self-consumption: the interplay of autophagy and apoptosis
2014 Standout
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Bax inhibitor-1: a highly conserved endoplasmic reticulum-resident cell death suppressor
2011
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response
2010
Protein Disulfide Isomerase A6 Controls the Decay of IRE1α Signaling via Disulfide-Dependent Association
2014
ER Proteostasis Control of Neuronal Physiology and Synaptic Function
2018
BCL-2 family: integrating stress responses at the ER to control cell demise
2017
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
2010
Endoplasmic reticulum protein BI-1 regulates Ca2+-mediated bioenergetics to promote autophagy
2012
Basic mechanisms of neurodegeneration: a critical update
2010
BH3‐only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α
2012
Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance
2009
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
PP2A blockade inhibits autophagy and causes intraneuronal accumulation of ubiquitinated proteins
2012
XBP1 mRNA Splicing Triggers an Autophagic Response in Endothelial Cells through BECLIN-1 Transcriptional Activation
2012
Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes
2017
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Early versus Late Parenteral Nutrition in Critically Ill Adults
2011 Standout
Protein folding stress in neurodegenerative diseases: a glimpse into the ER
2011
Bifunctional Apoptosis Regulator (BAR), an Endoplasmic Reticulum (ER)-associated E3 Ubiquitin Ligase, Modulates BI-1 Protein Stability and Function in ER Stress
2010
Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology
2009
The C Terminus of Bax Inhibitor-1 Forms a Ca2+-permeable Channel Pore
2011
Cell-free gene expression: an expanded repertoire of applications
2019
Autophagy and Neuronal Cell Death in Neurological Disorders
2012
ER stress and the unfolded protein response in neurodegeneration
2017
Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death
2017
Animal Models in the Study of the Unfolded Protein Response
2011
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome
2009
Proteostasis control by the unfolded protein response
2015
ER stress-induced cell death mechanisms
2013 Standout
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
Autophagy in immunity and inflammation
2011 StandoutNature
Targeting ER stress induced apoptosis and inflammation in cancer
2010
Sustained translational repression by eIF2α-P mediates prion neurodegeneration
2012 Nature
The unfolded protein response in familial amyotrophic lateral sclerosis
2010
Cell death pathways in Parkinson’s disease: proximal triggers, distal effectors, and final steps
2009
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Amyotrophic Lateral Sclerosis Pathogenesis: A Journey Through the Secretory Pathway
2010
Protein clearing pathways in ALS.
2011
A Fibrosis‐Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing Cholangitis
2020 StandoutNobel
Aggregation‐Induced Emission: The Whole Is More Brilliant than the Parts
2014 Standout
The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α
2011
Neuronal activity‐dependent local activation of dendritic unfolded protein response promotes expression of brain‐derived neurotrophic factor in cell soma
2017
Neural dysregulation of peripheral insulin action and blood pressure by brain endoplasmic reticulum stress
2011
Immunometabolism governs dendritic cell and macrophage function
2015 Standout
A Crucial Role for RACK1 in the Regulation of Glucose-Stimulated IRE1α Activation in Pancreatic β Cells
2010
Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering
2010
Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of Caenorhabditis elegans
2018 StandoutNobel
Dual and opposing roles of the unfolded protein response regulated by IRE1α and XBP1 in proinsulin processing and insulin secretion
2011
Regulation of basal cellular physiology by the homeostatic unfolded protein response
2010
Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
2014
Endoplasmic reticulum proteostasis impairment in aging
2017
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
2011 StandoutScience
Rapid and Sensitive Detection of Antigen from SARS-CoV-2 Variants of Concern by a Multivalent Minibinder-Functionalized Nanomechanical Sensor
2022 StandoutNobel
Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
2019
Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits
2016
Inflammatory Mechanisms in Obesity
2011 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
An unfolded protein-induced conformational switch activates mammalian IRE1
2017
Fine‐tuning PERK signaling for neuroprotection
2017
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Regulation of IRE1 RNase activity by the Ribonuclease inhibitor 1 (RNH1)
2018
Mutant superoxide dismutase 1-induced IL-1β accelerates ALS pathogenesis
2010
A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice
2009
Generation and Detection of Reactive Oxygen Species in Photocatalysis
2017 Standout
Minireview: Autophagy in Pancreatic β-Cells and Its Implication in Diabetes
2015
Pharmacological targeting of the unfolded protein response for disease intervention
2019
The unfolded protein response in neurodegenerative disorders – therapeutic modulation of the PERK pathway
2018
Immunogenic Cell Death in Cancer Therapy
2012 Standout
The Role of Atg Proteins in Autophagosome Formation
2011 StandoutNobel
XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development
2009
Bax inhibitor-1 is required for resisting the Early Brain Injury induced by subarachnoid hemorrhage through regulating IRE1-JNK pathway
2018
Works of Peter Thielen being referenced
Preservation of protein expression systems at elevated temperatures for portable therapeutic production
2017
Regulation of Memory Formation by the Transcription Factor XBP1
2016
Differential Effects of Unfolded Protein Response Pathways on Axon Injury-Induced Death of Retinal Ganglion Cells
2012
Diminishing Apoptosis by Deletion of Bax or Overexpression of Bcl-2 Does Not Protect against Infectious Prion ToxicityIn Vivo
2007
IRE1 signaling exacerbates Alzheimer’s disease pathogenesis
2017
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
2009
BAX Inhibitor-1 Is a Negative Regulator of the ER Stress Sensor IRE1α
2009
The Stress Rheostat: An Interplay Between the Unfolded Protein Response (UPR) and Autophagy in Neurodegeneration
2008
Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis
2008
Bracken: estimating species abundance in metagenomics data
2017
Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
2012