Citation Impact
Citing Papers
Expansion microscopy
2015 StandoutScience
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
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Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events
2011
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
2011 StandoutScience
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
Resistance of α-synuclein null mice to the parkinsonian neurotoxin MPTP
2002
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
2008 StandoutScience
Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia
2006 StandoutScience
Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo
2005 StandoutScience
Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease
2006
Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster
2012
COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord
2006
In situ click chemistry generation of cyclooxygenase-2 inhibitors
2017 Standout
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition
2004 Standout
Neuroinflammation in Parkinson's disease: a target for neuroprotection?
2009 Standout
Inflammatory processes in amyotrophic lateral sclerosis
2002
Human Interleukin-10 Gene Transfer Is Protective in a Rat Model of Parkinson's Disease
2008
Inhibition of thrombin‐induced microglial activation and NADPH oxidase by minocycline protects dopaminergic neurons in the substantia nigra in vivo
2005
Developmental Neuronal Death in Hippocampus Requires the Microglial CD11b Integrin and DAP12 Immunoreceptor
2008
Quality Control of Mitochondrial Proteostasis
2011
Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease
2005
Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
2008
Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease.
2004
Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons
2008
The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases
2016
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
2006 Standout
In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease
2005
Caenorhabditis elegans pathways that surveil and defend mitochondria
2014 StandoutNatureNobel
NADPH Oxidase Mediates Lipopolysaccharide-induced Neurotoxicity and Proinflammatory Gene Expression in Activated Microglia
2004
Microglial activation and dopamine terminal loss in early Parkinson's disease
2005
Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia
2004
Smoking, nicotine and Parkinson's disease
2004
Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis
2014
Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease
2008
ALS: A Disease of Motor Neurons and Their Nonneuronal Neighbors
2006
Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra
2002
Signaling the mitochondrial unfolded protein response
2012
Osteopontin is elevated in Parkinson’s disease and its absence leads to reduced neurodegeneration in the MPTP model
2007
Human Embryonic Stem Cell-Derived Motor Neurons Are Sensitive to the Toxic Effect of Glial Cells Carrying an ALS-Causing Mutation
2008
Microglial activation with atypical proinflammatory cytokine expression in a rat model of Parkinson's disease
2003
Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man
2004
Tumor necrosis factor-alpha receptor ablation in a chronic MPTP mouse model of Parkinson's disease
2004
Human neuromelanin induces neuroinflammation and neurodegeneration in the rat substantia nigra: implications for Parkinson's disease
2008
Gangliosides activate microglia via protein kinase C and NADPH oxidase
2004
Microglial response is poorly correlated with neurodegeneration following chronic, low-dose MPTP administration in monkeys
2003
Do inducers of apoptosis trigger caspase-independent cell death?
2005
From JNK to Pay Dirt: Jun Kinases, their Biochemistry, Physiology and Clinical Importance
2005
Cigarette smoke and nicotine protect dopaminergic neurons against the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Parkinsonian toxin
2003
Differential expression of inflammation‐ and apoptosis‐related genes in spinal cords of a mutant SOD1 transgenic mouse
model of familial amyotrophic lateral sclerosis
2001
Glial reactions in Parkinson's disease
2007
A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death
2009
Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism
2005
The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research
2009
Inflammation induces mitochondrial dysfunction and dopaminergic neurodegeneration in the nigrostriatal system
2006
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Mitochondria: In Sickness and in Health
2012 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with IκBα induction and block of NFκB and iNOS activation
2003
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
2005 StandoutNature
What causes cell death in Parkinson's disease?
2009
Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease
2008
Measuring reactive species and oxidative damagein vivoand in cell culture: how should you do it and what do the results mean?
2004 Standout
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Chemokines in the MPTP model of Parkinson’s disease: Absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration
2006
Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease
2006
Microglia induce neural cell death via a proximity-dependent mechanism involving nitric oxide
2006
Screening of innate immune receptors in neurodegenerative diseases: A similar pattern
2007
6‐Hydroxydopamine increases the hydroxylation and nitration of phenylalanine in vivo: implication of peroxynitrite formation
2001
The executioners sing a new song: killer caspases activate microglia
2011
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
Neurotoxic Effects of Lipopolysaccharide on Nigral Dopaminergic Neurons Are Mediated by Microglial Activation, Interleukin-1β, and Expression of Caspase-11 in Mice
2004
Nicotine, but not cotinine, partially protects dopaminergic neurons against MPTP-induced degeneration in mice
2001
A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis
2004
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial
2007
Continuous subcutaneous infusion of apomorphine rescues nigro-striatal dopaminergic terminals following MPTP injection in mice
2002
Autophagy in Human Health and Disease
2013 Standout
Behavioral and morphological effects of minocycline in the 6-hydroxydopamine rat model of Parkinson's disease
2006
Lenalidomide (Revlimid®) administration at symptom onset is neuroprotective in a mouse model of amyotrophic lateral sclerosis
2009
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Glial degeneration and reactive gliosis in alpha-synucleinopathies: the emerging concept of primary gliodegeneration
2006
Redox cycling of the herbicide paraquat in microglial cultures
2005
Genetic ablation of tumor necrosis factor‐alpha (TNF‐α) and pharmacological inhibition of TNF‐synthesis attenuates MPTP toxicity in mouse striatum
2004
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease
2005
The COX-2 inhibitor parecoxib produces neuroprotective effects in MPTP-lesioned rats
2007
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Inflammatory Cytokine Gene Polymorphisms and Increased Risk of Parkinson Disease
2007
Retinoic acid inhibits expression of TNF-? and iNOS in activated rat microglia
2004
Alzheimer's Disease
2010 Standout
Basic mechanisms of neurodegeneration: a critical update
2010
Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor‐α
2006
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Dopamine Quinones Activate Microglia and Induce a Neurotoxic Gene Expression Profile
2006
Neuroinflammatory mechanisms in Parkinson's disease: Potential environmental triggers, pathways, and targets for early therapeutic intervention
2007
A CD14 monocyte receptor polymorphism and genetic susceptibility to Parkinson's disease for females
2005
The Role of Glial Reaction and Inflammation in Parkinson's Disease
2003
Cyclooxygenases mRNA and protein expression in striata in the experimental mouse model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration to mouse
2004
Rise and fall of minocycline in neuroprotection: need to promote publication of negative results
2004
Microglia in the aging brain: relevance to neurodegeneration
2010
Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice
2003
Neuroglial activation and neuroinflammation in the brain of patients with autism
2004 Standout
Perturbations in Mitochondrial Dynamics Induced by Human Mutant PINK1 Can Be Rescued by the Mitochondrial Division Inhibitor mdivi-1
2010
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism
2005
Neuroinflammation and Oxidation/Nitration of α-Synuclein Linked to Dopaminergic Neurodegeneration
2008
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts
2011
MPTP as a Mitochondrial Neurotoxic Model of Parkinson's Disease
2004
Expanding insights of mitochondrial dysfunction in Parkinson's disease
2006
Targeting programmed cell death in neurodegenerative diseases
2003
Minocycline Up-regulates Bcl-2 and Protects against Cell Death in Mitochondria
2004
Glia and alpha-synuclein in neurodegeneration: A complex interaction
2015
The Hallmarks of Aging
2013 Standout
Thrombin-Induced Oxidative Stress Contributes to the Death of Hippocampal NeuronsIn Vivo: Role of Microglial NADPH Oxidase
2005
Pathological dynamics of activated microglia following medial forebrain bundle transection
2005
Progressive neurodegeneration and motor disabilities induced by chronic expression of IL-1β in the substantia nigra
2006
Presence of dendritic cells, MCP‐1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue
2003
Microglia: phagocyte and glia cell
2004
Molecular biology of amyotrophic lateral sclerosis: insights from genetics
2006
Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: protective effect of coenzyme Q10
2005
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
2011
Increased vulnerability of dopaminergic neurons in MPTP‐lesioned interleukin‐6 deficient mice
2002
Minocycline and neurodegenerative diseases
2008
Iron‐sulfur enzyme mediated mitochondrial superoxide toxicity in experimental Parkinson's disease
2004
Frailty in elderly people
2013 Standout
Mice lacking alpha-synuclein are resistant to mitochondrial toxins
2005
Minocycline enhances MPTP toxicity to dopaminergic neurons
2003
Trial of celecoxib in amyotrophic lateral sclerosis
2006
Neuroprotective effect of nicotine on dopaminergic neurons by anti‐inflammatory action
2007
Nitrated Alpha-Synuclein and Microglial Neuroregulatory Activities
2008
Involvement of Interferon-γ in Microglial-Mediated Loss of Dopaminergic Neurons
2007
COX-2-deficient mice are less prone to MPTP-neurotoxicity than wild-type mice
2003
Nonsteroidal Anti-inflammatory Drugs and the Risk of Parkinson Disease
2003
Parkinson's Disease
2003 Standout
Functional Repression of cAMP Response Element in 6-Hydroxydopamine-treated Neuronal Cells
2006
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
2002 Nature
Metallothionein Attenuates 3-Morpholinosydnonimine (SIN-1)-Induced Oxidative Stress in Dopaminergic Neurons
2003
Mitochondrial Dysfunction in Genetic Animal Models of Parkinson's Disease
2011
The Role of Microglia in Paraquat-Induced Dopaminergic Neurotoxicity
2005
Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway
2003
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Nitric oxide neurotoxicity in neurodegenerative diseases
2004
Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease
2011
Neuroimmunological Processes in Parkinson’s Disease and their Relation to α-Synuclein: Microglia as the Referee between Neuronal Processes and Peripheral Immunity
2013
The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: a tool to explore the pathogenesis of Parkinson's disease.
2003
Agonism of Peroxisome Proliferator Receptor-Gamma may have Therapeutic Potential for Neuroinflammation and Parkinsons Disease
2007
Dialogue between E. coli free radical pathways and the mitochondria of C. elegans
2015 StandoutNobel
The 1‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine Mouse Model
2003
Chronic microglial activation and progressive dopaminergic neurotoxicity
2007
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Synergistic dopaminergic neurotoxicity of MPTP and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease
2003
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease
2007
Microglial NADPH oxidase is a novel target for femtomolar neuroprotection against oxidative stress
2005
Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury
2004
Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase
2004
Role of Microglia in Central Nervous System Infections
2004
Immunologic diseases, anti-inflammatory drugs, and Parkinson disease: A case-control study
2006
Spermidine in health and disease
2018 StandoutScience
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Aggregated α‐synuclein activates microglia: a process leading to disease progression in Parkinson's disease
2005
MPP + ‐induced COX‐2 activation and subsequent dopaminergic neurodegeneration
2005
Glucocorticoid receptor deficiency increases vulnerability of the nigrostriatal dopaminergic system: critical role of glial nitric oxide
2003
Thrombin-Induced Microglial Activation Produces Degeneration of Nigral Dopaminergic NeuronsIn Vivo
2003
Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson’s disease
2007
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Nonsteroidal anti-inflammatory drugs and the incidence of Parkinson disease
2006
Critical role of microglial NADPH oxidase‐derived free radicals in the in vitro MPTP model of Parkinson's disease
2003
Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
2004 StandoutScience
Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: Implications for Parkinson's disease
2002
Exosomes as drug delivery vehicles for Parkinson's disease therapy
2015 Standout
Activation of microglia by human neuromelanin is NF‐κB‐dependent and involves p38 mitogen‐activated protein kinase: implications for Parkinson's disease
2003
Emerging Targets in Photopharmacology
2016 StandoutNobel
Inhibition of mitogen-activated protein kinase and stimulation of Akt kinase signaling pathways: Two approaches with therapeutic potential in the treatment of neurodegenerative disease
2007
UNRAVELING THE MECHANISMS INVOLVED IN MOTOR NEURON DEGENERATION IN ALS
2004
Critical Role for Microglial NADPH Oxidase in Rotenone-Induced Degeneration of Dopaminergic Neurons
2003
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease
2004
Peroxynitrite generated by inducible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytes
2005
Harnessing Functional Plasticity of Enzymes: A Fluorogenic Probe for Imaging 17β-HSD10 Dehydrogenase, an Enzyme Involved in Alzheimer's and Parkinson's Diseases
2007
Neurotoxins and neurotoxic species implicated in neurodegeneration
2004
Mitochondrial Aβ: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
2005
Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP‐induced neurotoxicity: role of TNF‐α 1
2006
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Oxidative stress in neurodegeneration: cause or consequence?
2004 Standout
ABAD enhances Aβ‐induced cell stress via mitochondrial dysfunction
2005
S -Nitrosylation of Parkin Regulates Ubiquitination and Compromises Parkin's Protective Function
2004 Science
Works of Peter Teismann being referenced
Neuroprotective Role of the Reaper-Related Serine Protease HtrA2/Omi Revealed by Targeted Deletion in Mice
2004
Dopamine mediates striatal malonate toxicity via dopamine transporter‐dependent generation of reactive oxygen species and D2 but not D1 receptor activation
2001
Cellular pathology of Parkinson?s disease: astrocytes, microglia and inflammation
2004
MPP+-induced toxicity in the presence of dopamine is mediated by COX-2 through oxidative stress
2011
Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response
2008
D-β-Hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease
2003
COX‐2 and Neurodegeneration in Parkinson's Disease
2003
Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease
2000
Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS
2002
The dopamine agonist pramipexole scavenges hydroxyl free radicals induced by striatal application of 6-hydroxydopamine in rats: an in vivo microdialysis study
2000
2004
Nuclear factor-κB activation is not involved in a MPTP model of Parkinson's disease
2001
Effects of nicotine on hydroxyl free radical formation in vitro and on MPTP-induced neurotoxicity in vivo
1998
The role of glial cells in Parkinsonʼs disease
2001
Effects of cytisine on hydroxyl radicals in vitro and MPTP-induced dopamine depletion in vivo
1998
Ablation of the Inflammatory Enzyme Myeloperoxidase Mitigates Features of Parkinson's Disease in Mice
2005
Is prostaglandin E2 a pathogenic factor in amyotrophic lateral sclerosis?
2006
Pathogenic role of glial cells in Parkinson's disease
2002
Salicylate protects against MPTP-induced impairments in dopaminergic neurotransmission at the striatal and nigral level in mice
1999
Malonate‐Induced Generation of Reactive Oxygen Species in Rat Strium Depends on Dopamine Release but Not on NMDA Receptor Activation
1999
Comparison of two independent aromatic hydroxylation assays in combination with intracerebral microdialysis to determine hydroxyl free radicals
2001
Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease
2002
Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration
2003
Free radical and nitric oxide toxicity in Parkinson's disease.
2003
NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
2003
D-β-Hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease
2003
Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis
2001
Increased levels of the pro-inflammatory prostaglandin PGE2 in CSF from ALS patients
2002
Increased expression of the pro‐inflammatory enzyme cyclooxygenase‐2 in amyotrophic lateral sclerosis
2001
JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease
2004
Glutathione—a review on its role and significance in Parkinson's disease
2009