Citation Impact
Citing Papers
Crystal Structure of a Mammalian Voltage-Dependent Shaker Family K + Channel
2005 StandoutScienceNobel
2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease
2014 Standout
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: Executive Summary
2014 Standout
2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary
2014 Standout
MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia
1999 Standout
Long QT Syndrome-associated Mutations in the Per-Arnt-Sim (PAS) Domain of HERG Potassium Channels Accelerate Channel Deactivation
1999
The open pore conformation of potassium channels
2002 StandoutNatureNobel
Calcium channels prove to be a real headache
1997
A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes
1997
Cryoballoon Ablation of Pulmonary Veins for Paroxysmal Atrial Fibrillation
2013
A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity
2014 StandoutNobel
Voltage‐dependent blockade of HERG channels expressed in Xenopus oocytes by external Ca2+ and Mg2+
1998
Effects of Na+ Channel Blocker, Pilsicainide, on HERG Current Expressed in HEK-293 Cells
2003
hERG potassium channels and cardiac arrhythmia
2006 Nature
Pericaval and Periannular Intra‐atrial Reentrant Tachycardias in Patients with Congenital Heart Disease
2003
Crystal Structure and Functional Analysis of the HERG Potassium Channel N Terminus
1998 StandoutNobel
A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
1995 Standout
The Human ∆1261 Mutation of the HERG Potassium Channel Results in a Truncated Protein That Contains a Subunit Interaction Domain and Decreases the Channel Expression
1997
β2‐Adrenergic receptor overexpression in the developing mouse heart: evidence for targeted modulation of ion channels
1999 StandoutNobel
Efficacy and safety of catheter ablation versus antiarrhythmic drugs for atrial fibrillation: a meta-analysis of randomized trials
2010
Courtship and Visual Defects of cacophony Mutants Reveal Functional Complexity of a Calcium-Channel α1 Subunit in Drosophila
1998 StandoutNobel
Ion channels: From idea to reality
1999 StandoutNobel
Genetic control of sodium channel function
2003
Molecular Dynamics Simulation for All
2018 Standout
Tricuspid Valve Dysfunction Following Pacemaker or Cardioverter-Defibrillator Implantation
2017
ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities
2008 Standout
Molecular and Cellular Mechanisms of Cardiac Arrhythmias
2001
Catheter ablation vs. antiarrhythmic drug treatment of persistent atrial fibrillation: a multicentre, randomized, controlled trial (SARA study)
2013
Radiofrequency Ablation as Initial Therapy in Paroxysmal Atrial Fibrillation
2012
Coiled Coils Direct Assembly of a Cold-Activated TRP Channel
2006 StandoutNobel
A structure-based computational workflow to predict liability and binding modes of small molecules to hERG
2020 StandoutNobel
Molecular driving forces determining potassium channel slow inactivation
2007
Mechanically Activated Ion Channels
2015 StandoutNobel
The long QT syndrome
1997
A Gate in the Selectivity Filter of Potassium Channels
2005
Structure of the NCoA-1/SRC-1 PAS-B Domain Bound to the LXXLL Motif of the STAT6 Transactivation Domain
2004 StandoutNobel
Dynamic conformational changes of extracellular S5–P linkers in the hERG channel
2005
Rationale and current perspective for early rhythm control therapy in atrial fibrillation
2011
Properties of HERG Channels Stably Expressed in HEK 293 Cells Studied at Physiological Temperature
1998
Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel
1996 Nature
Atrial fibrillation
2011
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Cryo-EM Structure of the Open Human Ether-à-go-go -Related K + Channel hERG
2017 Nobel
Genomic Structure of Three Long QT Syndrome Genes:KVLQT1, HERG,andKCNE1
1998
Courtship and Other Behaviors Affected by a Heat-Sensitive, Molecularly Novel Mutation in the cacophony Calcium-Channel Gene of Drosophila
2002 StandoutNobel
A constitutively open potassium channel formed by KCNQ1 and KCNE3
2000 StandoutNature
Hypertrophic Cardiomyopathy
2002 Standout
Modulation of HERG affinity for E‐4031 by [K+]o and C‐type inactivation
1997
The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions
2003 Standout
Molecular tuning of electroreception in sharks and skates
2018 StandoutNatureNobel
Hyperpolarization moves S4 sensors inward to open MVP, a methanococcal voltage-gated potassium channel
2003
Carboxy-terminal domain mediates assembly of the voltage-gated rat ether-a-go-go potassium channel
1997
Pathophysiological Mechanisms of Dominant and Recessive KvLQT1 K+ Channel Mutations Found in Inherited Cardiac Arrhythmias
1997
Novel KCNQ1 and HERG missense mutations in Dutch long-QT families
1999
Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association
2017 Standout
SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome
1995 Standout
A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns
1998
Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT3AReceptor Subunit
2004 StandoutNobel
The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells
2009 StandoutNobel
Guidelines for the Early Management of Patients With Acute Ischemic Stroke
2013 Standout
2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
2018
KvLQT1, a voltage-gated potassium channel responsible for human cardiac arrhythmias
1997
Two Isoforms of the MouseEther-a-go-go–Related Gene Coassemble to Form Channels With Properties Similar to the Rapidly Activating Component of the Cardiac Delayed Rectifier K+Current
1997
Increased Risk of Arrhythmic Events in Long-QT Syndrome With Mutations in the Pore Region of the Human Ether-a-go-go–Related Gene Potassium Channel
2002
Gain of Function Mutants: Ion Channels and G Protein-Coupled Receptors
2000
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation
2014 Standout
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease
2008 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Electrophysiological Characterization of an Alternatively Processed ERG K+Channel in Mouse and Human Hearts
1997
2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in Collaboration With the Society of Thoracic Surgeons
2019 Standout
Brugada Syndrome: Report of the Second Consensus Conference
2005 Standout
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease: Executive Summary
2008 Standout
Recent Stem Cell Advances: Induced Pluripotent Stem Cells for Disease Modeling and Stem Cell–Based Regeneration
2010 StandoutNobel
Radiofrequency Ablation vs Antiarrhythmic Drugs as First-Line Treatment of Paroxysmal Atrial Fibrillation (RAAFT-2)
2014
Identification of a deletion in plakoglobin in arrhythmogenic right ventricular cardiomyopathy with palmoplantar keratoderma and woolly hair (Naxos disease)
2000 Standout
The Structure of the Potassium Channel: Molecular Basis of K + Conduction and Selectivity
1998 StandoutScienceNobel
A Critical Assessment of Combined Ligand- and Structure-Based Approaches to hERG Channel Blocker Modeling
2011
2011 ACCF/AHA/HRS Focused Update on the Management of Patients With Atrial Fibrillation (Updating the 2006 Guideline)
2010
Worldwide Epidemiology of Atrial Fibrillation
2013 Standout
Arrhythmias in Adult Patients With Congenital Heart Disease
2007
Long-Term Results of Catheter Ablation in Paroxysmal Atrial Fibrillation
2010
Spectrum of Mutations in Long-QT Syndrome Genes
2000
C-type inactivation of voltage-gated K+ channels: Pore constriction or dilation?
2013
Gating currents associated with intramembrane charge displacement in HERG potassium channels
2003
2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
2020 Standout
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation
2014 Standout
A structural basis for drug-induced long QT syndrome
2000
Right Ventricular Function in Cardiovascular Disease, Part I
2008 Standout
Single-Channel Characteristics of Wild-Type IKs Channels and Channels formed with Two MinK Mutants that Cause Long QT Syndrome
1998
Impact of laboratory molecular diagnosis on contemporary diagnostic criteria for genetically transmitted cardiovascular diseases: hypertrophic cardiomyopathy, long-QT syndrome, and marfan syndrome : A statement for healthcare professionals from the councils on clinical cardiology, cardiovascular disease in the young, and basic science, american heart association
1998
Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics
1999 StandoutScience
Neurodevelopmental Outcomes in Children With Congenital Heart Disease: Evaluation and Management
2012 Standout
Rapid Inactivation Determines the Rectification and [K+]oDependence of the Rapid Component of the Delayed Rectifier K+Current in Cardiac Cells
1997
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Peter Spector being referenced
Electrical resynchronization induced by direct His-bundle pacing
2009
Potassium Channelopathies
1997
Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia.
1996
Characterization of Reentrant Circuit in Macroreentrant Right Atrial Tachycardia After Surgical Repair of Congenital Heart Disease
2001
Treatment of Atrial Fibrillation With Antiarrhythmic Drugs or Radiofrequency Ablation
2009
Class III Antiarrhythmic Drugs Block HERG, a Human Cardiac Delayed Rectifier K+Channel
1996
Fast inactivation causes rectification of the IKr channel.
1996