Citation Impact
Citing Papers
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
2001 StandoutScienceNobel
Oxygen-regulated and Transactivating Domains in Endothelial PAS Protein 1: Comparison with Hypoxia-inducible Factor-1α
1999 StandoutNobel
Nuclear Localization of Biliverdin Reductase in the Rat Kidney: Response to Nephrotoxins That Induce Heme Oxygenase-1
2001
The role of inorganic metals and metalloporphyrins in the induction of haem oxygenase and heat-shock protein 70 in human hepatoma cells
1993
Tissue-specific gene expression of heme oxygenase-1 (HO-1) and non-specific δ-aminolevulinate synthase (ALAS-N) in a rat model of septic multiple organ dysfunction syndrome
2000
Cloning and Characterization of PET100, a Gene Required for the Assembly of Yeast Cytochrome c Oxidase
1996
The heme synthesis and degradation pathways: role in oxidant sensitivity
2000
Assembly of mitochondrial cytochrome c-oxidase, a complicated and highly regulated cellular process
2006
Rac1 Activity Is Required for the Activation of Hypoxia-inducible Factor 1
2001 StandoutNobel
5‐Aminolevulinic Acid‐Based Photodynamic Therapy: Principles and Experimental Research
1997
Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit
1997 StandoutNobel
Regulation of heme oxygenase-2 by glucocorticoids in neonatal rat brain: characterization of a functional glucocorticoid response element
1997
Transactivation and Inhibitory Domains of Hypoxia-inducible Factor 1α
1997 StandoutNobel
Hypoxic Regulation of Lactate Dehydrogenase A
1995 StandoutNobel
Oxygen sensing and signaling: impact on the regulation of physiologically important genes
1999
A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology
2008 Standout
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1999 StandoutNatureNobel
Drug-Induced Hepatotoxicity
2003 Standout
COX15 Codes for a Mitochondrial Protein Essential for the Assembly of Yeast Cytochrome Oxidase
1997
Transcriptional Induction of Heme Oxygenase-1 Gene Expression by Okadaic Acid in Primary Rat Hepatocyte Cultures
2000
Purification and characterization of heme oxygenase from chick liver
1990
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
Yeast Cox11, a Protein Essential for Cytochrome cOxidase Assembly, Is a Cu(I)-binding Protein
2002
Purification and Characterization of Hypoxia-inducible Factor 1
1995 StandoutNobel
Characterization of , a Yeast Gene Involved in Copper Metabolism and Assembly of Cytochrome Oxidase
1996
GENE TRANSFER OF IMMUNOMODULATORY PEPTIDES CORRELATES WITH HEME OXYGENASE-1 INDUCTION AND ENHANCED ALLOGRAFT SURVIVAL 1
2000
Regulation of heme oxygenase gene expression by cobalt in rat liver and kidney
1990
Heme oxygenase induction by cadmium chloride: evidence for oxidative stress involvement
1995
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
A Chromatographic Assay for Heme Oxygenase Activity in Cultured Human Cells: Application to Artificial Heme Oxygenase Overexpression
1998
Perspectives on Oxygen Sensing
1999 StandoutNobel
The Role of the Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) in Hypoxic Induction of Gene Expression
1996 StandoutNobel
Induction of Haem Oxygenase as a Defence Against Oxidative Stress
1990
Hypoxia and Mitochondrial Inhibitors Regulate Expression of Glucose Transporter-1 via Distinct Cis-acting Sequences
1995 StandoutNobel
Carbon Monoxide and Nitric Oxide Suppress the Hypoxic Induction of Vascular Endothelial Growth Factor Gene via the 5′ Enhancer
1998 StandoutNobel
The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature
1993 Standout
Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen
1980 StandoutScience
Nitric Oxide And Carbon Monoxide Produce Activity-Dependent Long-Term Synaptic Enhancement in Hippocampus
1993 StandoutScienceNobel
Oxygen sensing in yeast: Evidence for the involvement of the respiratory chain in regulating the transcription of a subset of hypoxic genes
1999
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
1993 StandoutNobel
Induction of Endothelial PAS Domain Protein-1 by Hypoxia: Characterization and Comparison With Hypoxia-Inducible Factor-1α
1998 StandoutNobel
The Regulation of Heme Turnover and Carbon Monoxide Biosynthesis in Cultured Primary Rat Olfactory Receptor Neurons
1996
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
Oxygen Sensing and the Transcriptional Regulation of Oxygen-Responsive Genes in Yeast
1998
Life with 6000 Genes
1996 StandoutScience
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
Occurrence, Classification, and Biological Function of Hydrogenases: An Overview
2007 Standout
Zinc · protoporphyrin is a selective inhibitor of heme oxygenase activity in the neonatal rat
1981
Embryonal Carcinoma P19 Cells Produce Erythropoietin Constitutively But Express Lactate Dehydrogenase in an Oxygen-Dependent Manner
1998 StandoutNobel
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Heme Oxygenase: Recent Advances in Understanding Its Regulation and Role
1999
Metals as Regulators of Heme Metabolism
1977 Science
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.
1992 StandoutNobel
Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism.
1993 StandoutNobel
Regulation of the Erythropoietin Gene: Evidence That the Oxygen Sensor Is a Heme Protein
1988 Science
Pigment Epithelium-Derived Factor: A Potent Inhibitor of Angiogenesis
1999 StandoutScience
Cloning, sequencing and expression of cDNA for chick liver haem oxygenase. Comparison of avian and mammalian cDNAs and deduced proteins
1991
Biosynthesis of Metal Sites
2003
High efficiency transformation by direct microinjection of DNA into cultured mammalian cells
1980 StandoutNobel
Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice.
1991 StandoutNobel
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.
1996 StandoutNobel
Real-time measurements of endogenous CO production from vascular cells using an ultrasensitive laser sensor
2001
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.
1994 StandoutNobel
Metal induction of haem oxygenase without concurrent degradation of cytochrome P-450. Protective effects of compound SKF 525A on the haem protein
1982
Cluster analysis and display of genome-wide expression patterns
1998 Standout
Effectiveness of delta-aminolevulinic acid-induced protoporphyrin as a photosensitizer for photodynamic therapy in vivo.
1995
Purification and properties of bovine spleen heme oxygenase. Amino acid composition and sites of action of inhibitors of heme oxidation.
1982
New Developments in the Regulation of Heme Metabolism and Their Implications
1984
Metal ion-mediated regulation of heme oxygenase induction in cultured avian liver cells.
1982
Modulation of Acetaminophen-Induced Hepatotoxicity by the Xenobiotic Receptor CAR
2002 Science
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Function and induction of the microsomal heme oxygenase
1983
Induction of hepatic heme oxygenase activity by bromobenzene
1979
Microinjection studies of duck globin messenger RNA translation in human and avian cells
1976
Heme-Containing Oxygenases
1996 Standout
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
Heme oxygenase/carbon monoxide signaling pathways: Regulation and functional significance
2002
Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene.
1991 StandoutNobel
Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes
2004 Standout
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
1998 Standout
Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene.
1991 StandoutNobel
Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
2000 StandoutScience
Induction of Endothelial PAS Domain Protein-1 by Hypoxia: Characterization and Comparison With Hypoxia-Inducible Factor-1α
1998 StandoutNobel
Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia.
1993 StandoutNobel
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Oxidative stress resulting from ultraviolet A irradiation of human skin fibroblasts leads to a heme oxygenase-dependent increase in ferritin
1993
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Induction of Hypoxia-Inducible Factor-1, Erythropoietin, Vascular Endothelial Growth Factor, and Glucose Transporter-1 by Hypoxia: Evidence Against a Regulatory Role for Src Kinase
1997 StandoutNobel
Synthesis and secretion of plasma proteins by embryonic chick hepatocytes: changing patterns during the first three days of culture.
1978
Oxygen-dependent modulation of erythropoietin mRNA levels in isolated rat kidneys studied by RNase protection.
1990 StandoutNobel
Works of Peter Sinclair being referenced
Effect of Arsenite on Induction of CYP1A and CYP2H in Primary Cultures of Chick Hepatocytes
1998
Formation of cobalt protoporphyrin in the liver of rats. A mechanism for the inhibition of liver haem biosynthesis by inorganic cobalt
1979
Immunochemical detection of different isoenzymes of cytochrome P-450 induced in chick hepatocyte cultures
1989
Cobalt regulation of heme synthesis and degradation in avian embryo liver cell culture.
1977
Isolation of four forms of acetone-induced cytochrome P-450 in chicken liver by h.p.l.c. and their enzymic characterization
1990
Discussion
1998
Effects by heme, insulin, and serum albumin on heme and protein synthesis in chick embryo liver cells cultured in a chemically defined medium, and a spectrofluorometric assay for porphyrin composition.
1975
On the functions of the yeast COX10 and COX11 gene products.
1993