Citation Impact
Citing Papers
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
Increased sensitivity of UV-repair-deficient human cells to DNA bound platinum products which unlike thymine dimers are not recognized by an endonuclease extracted from Micrococcus luteus
1978
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
1999 Standout
Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation
1999 StandoutNatureNobel
Reaction of hematin with allylic fatty acid hydroperoxides: identification of products and implications for pathways of hydroperoxide-dependent epoxidation of 7,8-dihydroxy-7,8-dihydrobenzol[a]pyrene
1988
Carcinogen-mediated oxidant formation and oxidative DNA damage
1992
Genetic instabilities in human cancers
1998 StandoutNature
The oxidation of naphthalene and pyrene by cytochrome P450cam
1998
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
2011 StandoutNature
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Naphthalene?an environmental and occupational toxicant
2003
Sequence specificity of mutations induced by benzo[a]pyrene-7,8-diol-9,10-epoxide at endogenousaprt gene in CHO cells
1988
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
The approach to understanding aromatic hydrocarbon carcinogenesis. The central role of radical cations in metabolic activation
1992
The human ATR-mediated DNA damage checkpoint in a reconstituted system
2009 StandoutNobel
Shining a Light on Xeroderma Pigmentosum
2012
What works? Interventions for maternal and child undernutrition and survival
2008 Standout
Two genetic hits (more or less) to cancer
2001
Complementation of the xeroderma pigmentosum DNA repair synthesis defect withEscherichia coliUvrABC proteins in a cell-free system
1990 StandoutNobel
Intercalative DNA Binding of Model Compounds Derived From Metabolites of 7, 12-Dimethylbenz[a]anthracene
1984
Free radicals, antioxidant enzymes, and carcinogenesis
1990
Polycyclic aromatic hydrocarbons physically intercalate into duplex regions of denatured DNA
1987 Standout
Characterization of Rat‐Liver Microsomal Glutathione S‐Transferase Activity
1980
Double-stranded DNA stereoselectively binds benzo(a)pyrene diol epoxides
1979 Nature
ExCage
2014 StandoutNobel
Polarized fluorescence of polycyclic hydrocarbons in aqueous DNA solutions: Effect of flow-orientation
1967
p53 Mutations in Human Cancers
1991 StandoutScience
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
Protein Oxidation and Aging
1992 StandoutScience
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
1983 StandoutNature
Reaction of arene oxides with nucleosides
1977
Two-stage chemical oncogenesis in cultures of C3H/10T1/2 cells.
1976
Simian virus 40 large tumor antigen-immortalized normal human liver epithelial cells express hepatocyte characteristics and metabolize chemical carcinogens.
1993
Tumour promoter TPA enhances transformation of human leukocytes by Epstein–Barr virus
1979 StandoutNatureNobel
Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus
1984 StandoutNatureNobel
Nonenzymatic Covalent Posttranslational Modification of Proteins In Vivo
1985
Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.
1975 Standout
A SIMPLE METHOD FOR DETECTING ENVIRONMENTAL CARCINOGENS AS MUTAGENS*
1976
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
Hydrolysis of benzo[a]pyrene diol epoxide and its covalent binding to DNA proceed through similar rate-determining steps.
1984
Glutathione S-Transferases
1974 Standout
Biochemistry of Drug Oxidation and Reduction by Enzymes in Hepatic Endoplasmic Reticulum
1966
Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation
1983 StandoutScienceNobel
Binding of Nenzo[ a ]pyrene 7,8-Diol-9,10-Epoxides to DNA, RNA, and Protein of Mouse Skin Occurs with High Stereoselectivity
1978 Science
Prooxidant States and Tumor Promotion
1985 StandoutScience
ExBox: A Polycyclic Aromatic Hydrocarbon Scavenger
2012 StandoutNobel
Quantitative relationship between carcinogenecity and mutagenicity of polyaromatic hydrocarbons in Salmonnella typhimurium mutants
1975
DNA Damage as the Primary Cause of Aging
1981
The Chemical Effects ofNucleic Acid Alkylation and Their Relation to Mutagenesis and Carcinogen esis
1975
Probing the sequence-specific interaction of the cyclic AMP receptor protein with DNA by site-directed mutagenesis
1987
HUMAN ARTERIAL AND VENOUS TISSUES GENERATE PROSTACYCLIN (PROSTAGLANDIN X), A POTENT INHIBITOR OF PLATELET AGGREGATION
1977 StandoutNobel
Free Radical Mechanisms in Tissue Injury
1988
THE METABOLISM OF URETHANE AND RELATED COMPOUNDS
1965
Identification of the slow reacting substances from cat paws.
1980
Approach to risk assessment for genotoxic carcinogens based on data from the mouse skin initiation-promotion model.
1983
Hair dyes are mutagenic: identification of a variety of mutagenic ingredients.
1975
The Clonal Evolution of Tumor Cell Populations
1976 StandoutScience
The effects of antioxidants on skin tumor initiation and aryl hydrocarbon hydroxylase.
1977
Molecular structure of a left-handed double helical DNA fragment at atomic resolution
1979 StandoutNature
Electric linear dichroism study on the orientation of benzo[a]pyrene-7,8-dihydrodiol 9,10-oxide covalently bound to DNA
1978
Some current perspectives on chemical carcinogenesis in humans and experimental animals: Presidential Address.
1978
Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response.
1981 StandoutNobel
The origin of human cancers
1981 Nature
Oxygen radical-dependent epoxidation of (7S,8S)-dihydroxy-7,8-dihydrobenzo[a]pyrene in mouse skin in vivo. Stimulation by phorbol esters and inhibition by antiinflammatory steroids.
1992
Benzo[a]pyrene-7,8-dihydrodiol: Selective binding to single stranded DNA and inactivation of ØX174 DNA infectivity
1979
Chemical Carcinogens as Frameshift Mutagens: Salmonella DNA Sequence Sensitive to Mutagenesis by Polycyclic Carcinogens
1974
Highly specific and sensitive method for measuring nucleotide excision repair kinetics of ultraviolet photoproducts in human cells
2013 StandoutNobel
Cross-linking of DNA induced by chloroethyinitrosourea is prevented by O6-methyiguanine-DNA methyttransferase
1983 StandoutNobel
Dietary Carcinogens and Anticarcinogens
1983 StandoutScience
On the biochemical mechanism of tumorigenesis in mouse skin
1977
Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°
1991 StandoutScienceNobel
Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion.
1976
Tumor initiators and promoters in the induction of Epstein—Barr virus
1979 StandoutNobel
Characterization of slow reacting substances (SRSs) of rat basophilic leukemia (RBL-1) cells: effect of cysteine on SRS profile.
1980
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Carcinogenesis in vitro
1975
Evaluation of six short term tests for detecting organic chemical carcinogens and recommendations for their use
1976 StandoutNature
Pentalenolactone Biosynthesis. Molecular Cloning and Assignment of Biochemical Function to PtlI, a Cytochrome P450 of Streptomyces avermitilis
2006 StandoutNobel
Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection
1973 Standout
Characterization of reversible, physical binding of benzo[a]pyrene derivatives to DNA.
1982
Reactions of the UVRABC excision nuclease with DNA damaged by diamminedichloroplatinum(II)
1985 StandoutNobel
Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture
1968 Standout
Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air.
2002
Arene Oxides: A New Aspect of Drug Metabolism
1974 StandoutScience
Molecular analysis of spontaneous somatic mutants
1977 StandoutNatureNobel
HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease.
1994 StandoutNobel
The structure of a CAP–DNA complex having two cAMP molecules bound to each monomer
1997 StandoutNobel
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.
1975 Standout
An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens
1973
DISCUSSION PAPER: THE DETECTION OF MUTAGENIC METABOLITES OF CARCINOGENS IN URINE WITH THE SALMONELLA/MICROSOME TEST
1976
A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia
1985 StandoutScienceNobel
Liver microsomal metabolism of aflatoxin B 1 to a reactive derivative toxic to Salmonella typhimurium TA 1530.
1972
Interaction of nucleic acids. IV. Physical binding of 3,4-benzopyrene to nucleosides, nucleotides, nucleic acids, and nucleoprotein
1968
Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test
1975 Standout
Activation of microsomal glutathione S-transferase activity by sulfhydryl reagents
1979
Detection of Mutagenic Activity in Cigarette Smoke Condensates
1974
[28] Analysis of polycyclic aromatic hydrocarbons and their metabolites by high-pressure liquid chromatography
1978
Hypomethylation distinguishes genes of some human cancers from their normal counterparts
1983 StandoutNature
Effects of Some Chemical Mutagens and Carcinogens on Nucleic Acids
1966
Disruption by Carcinogens of the Hormone Dependent Association of Membranes with Polysomes
1971 Nature
Acetaminophen-induced hepatotoxicity
1981
New region of the simian virus 40 genome required for efficient viral transformation.
1978 StandoutNobel
5-Bromo-2′-deoxyuridine Potentiation of Transformation of Rat-Embryo Cells Induced In Vitro by 3-Methylcholanthrene: Induction of Rat Leukemia Virus gs Antigen in Transformed Cells
1973
Mutagenicity of chloroacetaldehyde, a possible metabolic product of 1,2-dichloroethane (ethylene dichloride), chloroethanol (ethylene chlorohydrin), vinyl chloride, and cyclophosphamide.
1975
DNA sequence selectivity of guanine–N7 alkylation by nitrogen mustards
1986 StandoutNobel
Identifying Environmental Chemicals Causing Mutations and Cancer
1979 Science
Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division.
1973
Carcinogens as Frameshift Mutagens: Metabolites and Derivatives of 2-Acetylaminofluorene and Other Aromatic Amine Carcinogens
1972
Chemical Carcinogenesis
1971
Preferential DNA repair in expressed genes.
1987
Works of Peter Sims being referenced
Effect of DNA repair on the cytotoxicity and mutagenicity of polycyclic hydrocarbon derivatives in normal and xeroderma pigmentosum human fibroblasts
1977
Epoxides as microsomal metabolites of polycyclic hydrocarbons
1971
Iodine deficiency in Papua New Guinea (sub-clinical iodine deficiency and salt iodization in the highlands of Papua New Guinea)
2004
K‐region epoxides of polycyclic hydrocarbons: Formation and further metabolism of benz[a] anthracene 5, 6‐oxide by human lung preparations
1973
METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 9,10-EPOXY-9,10-DIHYDROPHENANTHRENE IN RATS
1965
A modified two primer approach to oligonucleotide-directed in vitro mutagenesis
1985
The metabolism of benzo[a]pyrene by rat-liver homogenates
1967
Metabolism of polycyclic compounds. 15. The conversion of naphthalene into a derivative of glutathione by rat-liver slices
1960
Reactivity of the K-region epoxides of some polycyclic hydrocarbons towards the nucleic acids and proteins of BHK 21 cells
1971
Polycyclic hydrocarbon epoxides: The involvement of 8,9‐dihydro‐8,9‐dihydroxybenz (a) anthracene 10,11‐oxide in reactions with the DNA of benz (a) anthracene‐treated hamster embryo cells
1974
Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation and metabolism of epoxides related to 7,12-dimethylbenz[a]-anthracene
1973
Interactions of the k-region epoxides of phenanthrene and dibenz[a,h]anthracene with nucleic acids and histone
1970
Epoxides of Carcinogenic Polycyclic Hydrocarbons Are Frameshift Mutagens
1972 Science
The carcinogenicity of polycyclic hydrocarbon epoxides in newborn mice
1975
Some properties of “K-region” epoxides of polycyclic aromatic hydrocarbons
1973
Transformation of hamster embryo cells by epoxides and other derivatives of polycyclic hydrocarbons.
1972
Metabolism of polycyclic compounds. 21. The metabolism of phenanthrene in rabbits and rats: dihydrodihydroxy compounds and related glucosiduronic acids
1962
The covalent binding of polycyclic hydrocarbons to DNA in the skin of mice of different strains
1978
Malignant transformation of cells derived from mouse prostate by epoxides and other derivatives of polycyclic hydrocarbons.
1972
K-region epoxides of polycyclic hydrocarbons: Reactions with nucleic acids and polyribonucleotides
1973
Tumour-initiating activities on mouse skin of dihydrodiols derived from benzo[a]pyrene
1976
The formation of “K-region” epoxides as hepatic microsomal metabolites of 7-methylbenz[a]anthracene and 7,12-dimethylbenz[a]anthracene and their 7-hydroxymethyl derivatives
1973
Metabolism of polycyclic compounds. 17. The reaction of 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene with glutathione catalysed by tissue preparations
1960
Enzyme-catalysed reactions of polycyclic hydrocarbons with deoxyribonucleic acid and protein in vitro
1968
A quantitative determination of the covalent binding of a series of polycylic hydrocarbons to dna in mouse skin
1979
Mutagenicity to Mammalian Cells of Epoxides and Other Derivatives of Polycyclic Hydrocarbons
1971
Epoxides Derived from Various Polycyclic Hydrocarbons as Substrates of Homogeneous and Microsome‐Bound Epoxide Hydratase
1976
High microsome-mediated mutagenicity of the 3,4-dihydrodiol of 7-methylbenz[a]anthracene in S. typhimurium TA 98
1977
The metabolism of benz[a]anthracene and dibenz[a,h]anthracene and their 5,6-epoxy-5,6-dihydro derivatives by rat-liver homogenates
1965
Mutagenicity of non-K-region diols and diol-epoxides of benz(a)anthracene and benzo(a)pyrene in S. typhimurium TA 100
1975
Studies on the formation of hydrocarbon-deoxyribonucleoside products by the binding of derivatives of 7-methylbenz(a)anthracene to DNA in aqueous solution and in mouse embryo cells in culture.
1973
Induction of Adrenal Damage and Cancer with Metabolites of 7,12-Dimethylbenz(a)Anthracene
1965 Nature
Metabolism and activation of benzo[a]pyrene by mouse and rat skin in short-term organ culture and in vivo
1982
Epoxy derivatives of aromatic polycyclic hydrocarbons. The synthesis of dibenz[a,c]anthracene 10,11-oxide and its metabolism by rat liver preparations
1972
Binding of K-region epoxides and other derivatives of benz[a]anthracene and dibenz[a,h]anthracene to DNA, RNA and proteins of transformable cells
1972
Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation and metabolism of epoxides related to benzo[a]pyrene and to 7,8- and 9,10-dihydrobenzo[a]pyrene
1972
Metabolism of polycyclic compounds. 26. The hydroxylation of some aromatic hydrocarbons by the ascorbic acid model hydroxylating system and by rat-liver microsomes
1964
Epoxides in Polycyclic Aromatic Hydrocarbon Metabolism and Carcinogenesis
1974
Qualitative and quantitative studies on the metabolism of a series of aromatic hydrocarbons by rat-liver preparations
1970
The metabolism of dibenzo[a, h]pyrene and dibenzo[a, i]pyrene and related compounds by liver preparations and their enzyme-induced binding to cellular macromolecules
1973
Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide
1974 Nature
Metabolism of polycyclic compounds. 12. An acid-labile precursor of 1-naphthylmercapturic acid and naphthol: an N-acetyl-S- (1:2-dihydrohydroxynaphthyl)-l -cysteine
1958
The involvement of a diol‐epoxide in the metabolic activation of benzo(a)pyrene in human bronchial mucosa and in mouse skin
1976
The Preparation of 7-Hydroxymethylbenz[a]anthracene 5,6-Oxide and its Metabolism by Rat-liver Preparations
1972
The metabolism of benz[a]anthracene and dibenz[a,h]anthracene and their related “K-region” epoxides, cis-dihydrodiols and phenols by hamster embryo cells
1973
Conjugations with glutathione. Distribution of glutathione S-aryltransferase in vertebrate species
1964
Studies on the metabolism of 7-methylbenz-[a]anthracene and 7,12-dimethylbenz[a]-anthracene and its hydroxymethyl derivatives in rat liver and adrenal homogenates
1970
An enzyme from rat liver catalysing conjugations with glutathione
1961
Metabolism of polycyclic compounds. 18. The secretion of metabolites of naphthalene, 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene in rat bile
1961
The conversion of phenanthrene 9, 10-oxide and dibenz[a, h]anthracene 5, 6-oxide into dihydrodiols by a rat-liver microsomal enzyme
1970
Mutagenicity of Epoxides of Polycyclic Hydrocarbons correlates with Carcinogenicity of Parent Hydrocarbons
1971
Fluorescence spectral evidence that benzo(a)pyrene‐DNA products in mouse skin arise from diol‐epoxides
1975
The carcinogenic activities in mice of compounds related to 3‐methylcholanthrene
1967
Formation of K-region epoxides as microsomal metabolites of pyrene and benzo[a]pyrene
1972
Metabolism of polycyclic compounds. 23. The metabolism of pyrene in rats and rabbits
1964
In Vitro Transformation of Rodent Cells by K-Region Derivatives of Polycyclic Hydrocarbons
1971
The carcinogenic activities in mice of compounds related to benz[a]anthracene
1967
Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation of benz[a]anthracene 8,9-oxide and 10,11-dihydrobenz[a]anthracene 8,9-oxide and their metabolism by rat liver preparations
1971