Standout Papers
Citation Impact
Citing Papers
Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart
2014
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
Specification of tissue-resident macrophages during organogenesis
2016 Science
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
2015 StandoutScience
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
The pancreas anatomy conditions the origin and properties of resident macrophages
2015
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
2011 StandoutScience
Cellular and Molecular Identity of Tumor-Associated Macrophages in Glioblastoma
2017
New tools for studying microglia in the mouse and human CNS
2016
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
2012 StandoutScience
The Fractalkine Receptor but Not CCR2 Is Present on Microglia from Embryonic Development throughout Adulthood
2011
Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies
2016
The dynamics of monocytes and microglia in Alzheimer’s disease
2015
Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models
2018
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
The Lifespan and Turnover of Microglia in the Human Brain
2017
Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
2014
Regulation of macrophage development and function in peripheral tissues
2015
Siglec functions of microglia
2014
Microglia in the developing brain: A potential target with lifetime effects
2012
Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression
2017
Origin of monocytes and macrophages in a committed progenitor
2013
Monocyte recruitment during infection and inflammation
2011 Standout
Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex
2014
The Blood–Brain Barrier
2015 Standout
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Comparison of polarization properties of human adult microglia and blood‐derived macrophages
2012
The immune system and developmental programming of brain and behavior
2012
Priming the Inflammatory Pump of the CNS after Traumatic Brain Injury
2015
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Host tissue determinants of tumour immunity
2019
Tissue-Resident Macrophage Ontogeny and Homeostasis
2016
Microglial immune checkpoint mechanisms
2018
TGF‐β signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment
2012
The myeloid cells of the central nervous system parenchyma
2010 Nature
Wild-type microglia arrest pathology in a mouse model of Rett syndrome
2012 Nature
Astrocytes and Microglia as Major Players of Myelin Production in Normal and Pathological Conditions
2020
Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli
2015
Glial Cell Development and Function in Zebrafish
2014
Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species
2013 Standout
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
2014 StandoutNature
Dendritic Cell and Macrophage Heterogeneity In Vivo
2011
Origin of Microglia: Current Concepts and Past Controversies
2015
Origin and differentiation of microglia
2013
Microglial cell origin and phenotypes in health and disease
2011 Standout
Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing
2018
A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
2013
Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System
2015
The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?
2014
Organotypic Neurovascular Models: Past Results and Future Directions
2019
Intestinal macrophages: well educated exceptions from the rule
2013
Phagocytosis of apoptotic cells in homeostasis
2015
Tissue-resident macrophages
2013 Standout
Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight
2018
Developmental control of macrophage function
2017
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
2012
Nuclear Receptors License Phagocytosis by Trem2+Myeloid Cells in Mouse Models of Alzheimer's Disease
2015
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
Mechanism of splenic cell death and host mortality in a Plasmodium yoelii malaria model
2017
Repertoire of microglial and macrophage responses after spinal cord injury
2011 Standout
TAM receptors regulate multiple features of microglial physiology
2016 Nature
Macrophage heterogeneity and acute inflammation
2011
Absence of Colony Stimulation Factor-1 Receptor Results in Loss of Microglia, Disrupted Brain Development and Olfactory Deficits
2011
Zika virus: from an obscurity to a priority
2018
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Neuronal and microglial regulators of cortical wiring: usual and novel guideposts
2015
Studying the mononuclear phagocyte system in the molecular age
2011
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages
2014
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Factors regulating microglia activation
2013
Activation of microglial N‐methyl‐D‐aspartate receptors triggers inflammation and neuronal cell death in the developing and mature brain
2012
Sex differences in microglial colonization of the developing rat brain
2011
Macrophage-Restricted Interleukin-10 Receptor Deficiency, but Not IL-10 Deficiency, Causes Severe Spontaneous Colitis
2014
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
2012
Stress-Induced Recruitment of Bone Marrow-Derived Monocytes to the Brain Promotes Anxiety-Like Behavior
2013
Depression as a Microglial Disease
2015
Sublime Microglia: Expanding Roles for the Guardians of the CNS
2014
Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R
2012
The nuclear receptor LXRα controls the functional specialization of splenic macrophages
2013
A timeline of tumour-associated macrophage biology
2023
Host microbiota constantly control maturation and function of microglia in the CNS
2015 Standout
The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation
2012
Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
2011
Sex, glia, and development: Interactions in health and disease
2012
Identification of a unique TGF-β–dependent molecular and functional signature in microglia
2013 Standout
The development and maintenance of resident macrophages
2015
Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
2014
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
2016 Standout
A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation
2013
Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages
2014
The immunology of stroke: from mechanisms to translation
2011 Standout
Axon Initial Segment–Associated Microglia
2015
Functional Specialization of Skin Dendritic Cell Subsets in Regulating T Cell Responses
2015
Microglia: unique and common features with other tissue macrophages
2014
The Central Nervous System and the Gut Microbiome
2016
Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis
2012 Standout
Tissue-Resident CD169+ Macrophages Form a Crucial Front Line against Plasmodium Infection
2016
Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair
2013
The blood–brain barrier
2016
Macrophages as regulators of tumour immunity and immunotherapy
2019 Standout
Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
2016 Standout
Monocytes and macrophages: developmental pathways and tissue homeostasis
2014
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
2013 Standout
Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation
2014
Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures
2017
The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory
2015
Phenotypic characterization of a Csf1r haploinsufficient mouse model of adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP)
2014
Macrophage Metabolism As Therapeutic Target for Cancer, Atherosclerosis, and Obesity
2017
Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation
2014
Phagocytic glial cells: sculpting synaptic circuits in the developing nervous system
2013
Oncofetal reprogramming in tumour development and progression
2022
Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts
2011
The anatomical and cellular basis of immune surveillance in the central nervous system
2012
Myeloid cells — targets of medication in multiple sclerosis
2016
Fine-tuning of type I IFN-signaling in microglia — implications for homeostasis, CNS autoimmunity and interferonopathies
2015
Re-establishment of Anxiety in Stress-Sensitized Mice Is Caused by Monocyte Trafficking from the Spleen to the Brain
2013
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria
2016
Re(de)fining the dendritic cell lineage
2012
Injured sensory neuron–derived CSF1 induces microglial proliferation and DAP12-dependent pain
2015
Complex invasion pattern of the cerebral cortex bymicroglial cells during development of the mouse embryo
2012
Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging
2017
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
2014 Standout
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
2011
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
A polarizing question: do M1 and M2 microglia exist?
2016
The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1
2012
Stroma-Derived Interleukin-34 Controls the Development and Maintenance of Langerhans Cells and the Maintenance of Microglia
2012
Origin and Functions of Tissue Macrophages
2014
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
2012 Standout
Microglial Corpse Clearance: Lessons From Macrophages
2020
Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
2014
Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy
2017
Metchnikoff's policemen: macrophages in development, homeostasis and regeneration
2011
A Combination of Ontogeny and CNS Environment Establishes Microglial Identity
2018
GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells
2012
Microglia: New Roles for the Synaptic Stripper
2013
Emerging Roles for CSF-1 Receptor and its Ligands in the Nervous System
2016
Inflammation in Alzheimer’s disease: Lessons learned from microglia-depletion models
2016
Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury
2015
Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival
2013
Neuroinflammation: the devil is in the details
2016 Standout
Microglia engulf viable newborn cells in the epileptic dentate gyrus
2016
Isolation and Culture of Microglia
2018
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Mechanisms of Organ Injury and Repair by Macrophages
2016
Inflammation and Neuroprotection in Traumatic Brain Injury
2015
MRI demonstrates glutamine antagonist-mediated reversal of cerebral malaria pathology in mice
2018
Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer’s disease
2015
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
Multiple Sclerosis
2018 Standout
Microglia: Scapegoat, Saboteur, or Something Else?
2013 Science
Targeting miR ‐155 restores abnormal microglia and attenuates disease in SOD 1 mice
2014
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation
2012
Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages
2016
New insights on the role of microglia in synaptic pruning in health and disease
2015
P2Y12receptor is expressed on human microglia under physiological conditions throughout development and is sensitive to neuroinflammatory diseases
2016
Modulation of three key innate immune pathways for the most common retinal degenerative diseases
2018
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Plenary Perspective: The complexity of constitutive and inducible gene expression in mononuclear phagocytes
2012
Next generation transcriptomics and genomics elucidate biological complexity of microglia in health and disease
2015
Review: Microglia of the aged brain: primed to be activated and resistant to regulation
2012
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Systemic Analysis of PPARγ in Mouse Macrophage Populations Reveals Marked Diversity in Expression with Critical Roles in Resolution of Inflammation and Airway Immunity
2012
Complementary roles of gasotransmitters CO and H2S in sleep apnea
2017 StandoutNobel
Microbiome–microglia connections via the gut–brain axis
2018
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
2013
Regenerative Capacity of Macrophages for Remyelination
2016
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
2011 StandoutNobel
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Estrogens, Neuroinflammation, and Neurodegeneration
2016
Macrophage plasticity and polarization in tissue repair and remodelling
2012 Standout
A neuroprotective role for microglia in prion diseases
2016
Physiology of Microglia
2011 Standout
Macrophages: Gatekeepers of Tissue Integrity
2013
The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting
2013 Standout
Works of Peter See being referenced
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
2010 StandoutScience
The earliest intrathymic precursors of CD8α+ thymic dendritic cells correspond to myeloid‐type double‐negative 1c cells
2011
Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma
2016
Cross-reactive dengue human monoclonal antibody prevents severe pathologies and death from Zika virus infections
2017
CD8+ T Cells and IFN-γ Mediate the Time-Dependent Accumulation of Infected Red Blood Cells in Deep Organs during Experimental Cerebral Malaria
2011
C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages
2015
Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages
2012