Citation Impact
Citing Papers
IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC–activated Th2 memory cells
2007
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
2009 StandoutScience
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Number of T Reg Cells That Differentiate Does Not Increase upon Encounter of Agonist Ligand on Thymic Epithelial Cells
2004
Identification of an interleukin (IL)-25–dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion
2006
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Targeted cell killing by reconstituted caspases
2007 StandoutNobel
IL-25 regulates Th17 function in autoimmune inflammation
2007
Cutting Edge: Roles of Caspase-8 and Caspase-10 in Innate Immune Responses to Double-Stranded RNA
2006
A mechanism of resistance to TRAIL/Apo2L-induced apoptosis of newly established glioma cell line and sensitisation to TRAIL by genotoxic agents
2003
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
The Long Form of FLIP Is an Activator of Caspase-8 at the Fas Death-inducing Signaling Complex
2002
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Identification of a ligand for glucocorticoid-induced tumor necrosis factor receptor constitutively expressed in dendritic cells
2003
Development and Characterization of Nonpeptidic Small Molecule Inhibitors of the XIAP/Caspase-3 Interaction
2003
Interleukin-17 family and IL-17 receptors
2003
CD26: a surface protease involved in T-cell activation
1994
TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO
2002
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Necroptosis and its role in inflammation
2015 StandoutNature
The immune geography of IgA induction and function
2007
Tumor Necrosis Factor Receptor (TNFR)-associated Factor 5 Is a Critical Intermediate of Costimulatory Signaling Pathways Triggered by Glucocorticoid-induced TNFR in T Cells
2006
Interleukin-17 Family Members and Inflammation
2004 Standout
Follicular Dendritic Cells and Germinal Centers
1996
Cloning and characterization of GITR ligand
2003
Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis
2016
The CD95(APO-1/Fas) DISC and beyond
2003
Caspases: pharmacological manipulation of cell death
2005 Standout
From bench to clinic with apoptosis-based therapeutic agents
2000 Nature
Tumor necrosis factor, cancer and anticancer therapy
2004
Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity
2000
Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity
2001
Nature's TRAIL—On a Path to Cancer Immunotherapy
2003
Promoting apoptosis as a strategy for cancer drug discovery
2005
Malignant astrocytic glioma: genetics, biology, and paths to treatment
2007 Standout
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Pattern Recognition Receptors and Inflammation
2010 Standout
The kiss of death: promises and failures of death receptors and ligands in cancer therapy
2001
Role of caspases in the regulation of apoptotic pancreatic islet beta‐cells death
2004
IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
2007 StandoutNature
Apoptotic mechanisms in the control of erythropoiesis
2004
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8
2002
Signalling pathways of the TNF superfamily: a double-edged sword
2003 Standout
Caspase Functions in Cell Death and Disease
2013 Standout
Interdimer processing mechanism of procaspase-8 activation
2003
Immunity, Inflammation, and Cancer
2010 Standout
Apo2L/TRAIL and its death and decoy receptors
2003
Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency
2002 Nature
Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis
2003
Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
2002
IL-17E, a Novel Proinflammatory Ligand for the IL-17 Receptor Homolog IL-17Rh1
2001
IAP proteins: blocking the road to death's door
2002
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
2013 StandoutNature
Death and anti-death: tumour resistance to apoptosis
2002 Standout
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
Tumor necrosis factor signaling
2003 Standout
The CD95 Type I/Type II model
2003
Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
2009 StandoutNature
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes
2003 Standout
Soluble glucocorticoid‐induced tumor necrosis factor receptor (sGITR) increased MMP‐9 activity in murine macrophage
2003
Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
2000 Standout
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
2010 StandoutNature
Interleukin-17: a mediator of inflammatory responses
2004
Cancer-related inflammation
2008 StandoutNature
TRAIL Triggers Apoptosis in Human Malignant Glioma Cells Through Extrinsic and Intrinsic Pathways
2003
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
2008 StandoutNature
TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway
2008
Reactive oxygen species, cellular redox systems, and apoptosis
2010 Standout
Gene Structure and Chromosomal Assignment of Mouse GITR, a Member of the Tumor Necrosis Factor/Nerve Growth Factor Receptor Family
2000
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
2002
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response
2006
A decade of caspases
2003
CD4+CD25+ Immunoregulatory T Cells
2002
CD95's deadly mission in the immune system
2000 Nature
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
2004 StandoutNature
Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance
2002 StandoutNobel
Mechanisms of caspase activation
2003
Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV
2003
JNK-Mediated BIM Phosphorylation Potentiates BAX-Dependent Apoptosis
2003
Engagement of Glucocorticoid-Induced TNFR Family-Related Receptor on Effector T Cells by its Ligand Mediates Resistance to Suppression by CD4+CD25+ T Cells
2004
Costimulation via Glucocorticoid-Induced TNF Receptor in Both Conventional and CD25+ Regulatory CD4+ T Cells
2004 StandoutNobel
Focus on Extracellular Vesicles: New Frontiers of Cell-to-Cell Communication in Cancer
2016
Signaling by the TNF Receptor Superfamily and T Cell Homeostasis
2000
The Pathophysiology of Mitochondrial Cell Death
2004 StandoutScience
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
2006 StandoutNature
Elimination of Hepatic Metastases of Colon Cancer Cells via p53-Independent Cross-Talk between Irinotecan and Apo2 Ligand/TRAIL
2004
Characterisation of tumour‐derived microvesicles in cancer patients' blood and correlation with clinical outcome
2017
Glucocorticoids in T Cell Development and Function
2000
The costimulatory activity of the CD26 antigen requires dipeptidyl peptidase IV enzymatic activity.
1993
The protein structures that shape caspase activity, specificity, activation and inhibition
2004
Two Adjacent Trimeric Fas Ligands Are Required for Fas Signaling and Formation of a Death-Inducing Signaling Complex
2003
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
2018 StandoutNobel
Direct Association of Adenosine Deaminase with a T Cell Activation Antigen, CD26
1993 Science
Caspase-10 is an initiator caspase in death receptor signaling
2001
The Biology of Interleukin-2
2007
Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production
2002
Agonist Anti-GITR Antibody Enhances Vaccine-Induced CD8+ T-Cell Responses and Tumor Immunity
2006 StandoutNobel
FLICE-Inhibitory Proteins: Regulators of Death Receptor-Mediated Apoptosis
2001
Immune Cell Infiltration and Tertiary Lymphoid Structures as Determinants of Antitumor Immunity
2018
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Regulation of Fas-associated Death Domain Interactions by the Death Effector Domain Identified by a Modified Reverse Two-hybrid Screen
2002
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1α (SDF-1α) and SDF-1β are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage
1998 StandoutNobel
Biology and biogenesis of shed microvesicles
2016
Functional expression of CD43 on human natural killer cells
1999
Reiterative Recombination for the in vivo assembly of libraries of multigene pathways
2011
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Distinct Signaling Pathways in TRAIL- versus Tumor Necrosis Factor-Induced Apoptosis
2006
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells
2003
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
2014 Standout
GITR Activation Induces an Opposite Effect on Alloreactive CD4+ and CD8+ T Cells in Graft-Versus-Host Disease
2004 StandoutNobel
Glucocorticoid-Induced TNF Receptor Functions as a Costimulatory Receptor That Promotes Survival in Early Phases of T Cell Activation
2005
c-FLIPL is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis
2002
Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles
2014 Standout
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Works of Peter Schow being referenced
Apo2L/TRAIL-Dependent Recruitment of Endogenous FADD and Caspase-8 to Death Receptors 4 and 5
2000
Selective modulation of human natural killer cells in vivo after prolonged infusion of low dose recombinant interleukin 2.
1993
Tumor-cell resistance to death receptor–induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
2002
Death Receptor Recruitment of Endogenous Caspase-10 and Apoptosis Initiation in the Absence of Caspase-8
2001
Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease
2012
Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection
2011
Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR
1999
Differential responses to interleukin 2 define functionally distinct subsets of human natural killer cells
1992
APRIL-Deficient Mice Have Normal Immune System Development
2004
Follicular dendritic cells inhibit human B-lymphocyte proliferation
1992
Cell surface modulation of CD26 by anti-1F7 monoclonal antibody. Analysis of surface expression and human T cell activation.
1990
Forced Expression of Murine IL-17E Induces Growth Retardation, Jaundice, a Th2-Biased Response, and Multiorgan Inflammation in Mice
2001