Standout Papers
- Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site (2017)
- A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response (2016)
- Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue (2016)
Citation Impact
Citing Papers
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice
2021 StandoutScienceNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Sulfur [ 18 F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis
2021 StandoutNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN
2024 StandoutNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses
2018
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification
2019 StandoutNobel
Pre-fusion structure of a human coronavirus spike protein
2016 Nature
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Modular click chemistry libraries for functional screens using a diazotizing reagent
2019 StandoutNatureNobel
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Bottom-up de novo design of functional proteins with complex structural features
2021
A new coronavirus associated with human respiratory disease in China
2020 StandoutNature
Improving de novo protein binder design with deep learning
2023 StandoutNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Opportunities and challenges in design and optimization of protein function
2024
T-cell immunity of SARS-CoV: Implications for vaccine development against MERS-CoV
2016
A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice
2020 StandoutNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
2020 Standout
Unique Binding Specificities of Proteins toward Isomeric Asparagine-Linked Glycans
2019
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery
2020 StandoutNobel
Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate
2022
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
De novo protein design by inversion of the AlphaFold structure prediction network
2023
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
Rapid Diagnostic Assay for Intact Influenza Virus Using a High Affinity Hemagglutinin Binding Protein
2017 StandoutNobel
A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
2017 StandoutNobel
Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein
2017
Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF4 Hub
2017 StandoutNobel
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
SuFEx Chemistry of Thionyl Tetrafluoride (SOF4) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates
2018 StandoutNobel
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
Optimal activation of Fc-mediated effector functions by influenza virus hemagglutinin antibodies requires two points of contact
2016
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins
2019 StandoutNobel
Peptide-binding specificity prediction using fine-tuned protein structure prediction networks
2023 StandoutNobel
Computational design of mixed chirality peptide macrocycles with internal symmetry
2020 StandoutNobel
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
2020 StandoutScience
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1
2021 StandoutNobel
Antibody-dependent enhancement of influenza disease promoted by increase in hemagglutinin stem flexibility and virus fusion kinetics
2019
Rational Engineering of a Designed Protein Cage for siRNA Delivery
2018
Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus
2016
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Development of a tunable diode laser absorption spectrometer for measurements of the ratio in methane
1993 StandoutNobel
A Heck–Matsuda Process for the Synthesis of β‐Arylethenesulfonyl Fluorides: Selectively Addressable Bis‐electrophiles for SuFEx Click Chemistry
2016 StandoutNobel
Human coronaviruses OC43 and HKU1 bind to 9- O -acetylated sialic acids via a conserved receptor-binding site in spike protein domain A
2019
Palladium‐Catalyzed Fluorosulfonylvinylation of Organic Iodides
2017 StandoutNobel
Essentials of de novo protein design: Methods and applications
2018
Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody
2020 StandoutNobel
A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
2017 StandoutNobel
Progress toward active or passive HIV-1 vaccination
2016
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Works of Peter S. Lee being referenced
Receptor mimicry by antibody F045–092 facilitates universal binding to the H3 subtype of influenza virus
2014
Structural Characterization of Viral Epitopes Recognized by Broadly Cross-Reactive Antibodies
2014
Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site
2017 StandoutNobel
A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response
2016 StandoutNobel
Recent H3N2 Viruses Have Evolved Specificity for Extended, Branched Human-type Receptors, Conferring Potential for Increased Avidity
2016
Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex
2014
Structural insights into key sites of vulnerability on HIV ‐1 Env and influenza HA
2012
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
High resolution infrared diode laser spectroscopy for isotope analysis—Measurement of isotopic carbon monoxide
1986
Characterization of a Broadly Neutralizing Monoclonal Antibody That Targets the Fusion Domain of Group 2 Influenza A Virus Hemagglutinin
2014