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SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins
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SH3-dependent assembly of the phagocyte NADPH oxidase.
1994
Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-like Receptor-2
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Restoration of superoxide generation to a chronic granulomatous disease- derived B-cell line by retrovirus mediated gene transfer
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Neutrophils in Human Diseases
1987
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2000
Two Cytosolic Neutrophil Oxidase Components Absent in Autosomal Chronic Granulomatous Disease
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POSSIBLE ROLE FOR IMPAIRED RENAL PROSTAGLANDIN PRODUCTION IN PATHOGENESIS OF HYPORENINÆMIC HYPOALDOSTERONISM
1978
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Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b.
1988
Specific requirement for two ADF/cofilin isoforms in distinct actin-dependent processes inCaenorhabditis elegans
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The Arachidonate-activable, NADPH Oxidase-associated H+ Channel
1995
The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex
1987 Nature
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1992
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1994
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1988
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1988 Science
Cytochrome b558-negative, autosomal recessive chronic granulomatous disease: two new mutations in the cytochrome b558 light chain of the NADPH oxidase (p22-phox).
1992
Renal Syndromes Associated with Nonsteroidal Antiinflammatory Drugs
1984 Standout
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1992
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1987
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2002
Evidence for a functional cytoplasmic domain of phagocyte oxidase cytochrome b558.
1990
PU.1 as an essential activator for the expression of gp91phoxgene in human peripheral neutrophils, monocytes, and B lymphocytes
1998
Free Radicals in the Physiological Control of Cell Function
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The p47phox mouse knock-out model of chronic granulomatous disease.
1995
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Cloning of a 67-kD Neutrophil Oxidase Factor with Similarity to a Noncatalytic Region of p60 c-src
1990 Science
Works of Peter Rowe being referenced
Degradation of MEPE, DMP1, and Release of SIBLING ASARM-Peptides (Minhibins): ASARM-Peptide(s) Are Directly Responsible for Defective Mineralization in HYP
2007
MEPE has the properties of an osteoblastic phosphatonin and minhibin
2003
Use of Alu-PCR to characterize hybrids containing multiple fragments and to generate new Xp21.3–p22.2 markers
1992
Serum MEPE-ASARM-peptides are elevated in X-linked rickets (HYP): implications for phosphaturia and rickets
2004
MEPE is a novel regulator of growth plate cartilage mineralization
2012
Correction of the mineralization defect in hyp mice treated with protease inhibitors CA074 and pepstatin
2006
MEPE, a New Gene Expressed in Bone Marrow and Tumors Causing Osteomalacia
2000
Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia
2008
Genomic Organization of the Human PEX Gene Mutated in X-Linked Dominant Hypophosphatemic Rickets
1997
Distribution of mutations in the PEX gene in families with X-linked hypophosphataemic rickets (HYP)
1997
Mapping of human non‐muscle type cofilin (CFL1) to chromosome 11q13 and muscle‐type cofilin (CFL2) to chromosome 14
1996
Candidate 56 and 58 kDa protein(s) responsible for mediating the renal defects in oncogenic hypophosphatemic osteomalacia
1996
Non-random distribution of mutations in the PHEX gene, and under-detected missense mutations at non-conserved residues
1999
MEPE’s Diverse Effects on Mineralization
2009
Regulation of Bone−Renal Mineral and Energy Metabolism: The PHEX, FGF23, DMP1, MEPE ASARM Pathway
2012
Analysis of the human hephaestin gene and protein: comparative modelling of the N-terminus ecto-domain based upon ceruloplasmin
2002
Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE–ASARM motif: a model for impaired mineralization in X-linked rickets (HYP)
2004
Phosphorylated acidic serine–aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activity
2007
A PHEX Gene Mutation Is Responsible for Adult-Onset Vitamin D-Resistant Hypophosphatemic Osteomalacia: Evidence That the Disorder Is Not a Distinct Entity from X-Linked Hypophosphatemic Rickets1
1998
Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism
2011
Syndrome of Hyporeninemic Hypoaldosteronism and Hyperkalemia in Renal Disease
1973
Autosomal recessive chronic granulomatous disease caused by deletion at a dinucleotide repeat.
1991
The X-linked chronic granulomatous disease gene codes for the β-chain of cytochrome b−245
1987 Nature
Structure of the Core Oligosaccharide from the Lipopolysaccharide of Pseudomonas aeruginosa PAC1R and Its Defective Mutants
1983