Citation Impact
Citing Papers
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
2010 StandoutScience
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
2003 StandoutNobel
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
2007 StandoutNobel
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Role of viruses in etiology and pathogenesis of multiple sclerosis
2001
Follicular dendritic cells are a major reservoir for human immunodeficiency virus type 1 in lymphoid tissues facilitating infection of CD4+ T-helper cells.
1992
Hallmarks of Cancer: The Next Generation
2011 Standout
Human Endogenous Retroviruses in Neurological Diseases
2018
Increased mRNA Expression of IL‐10 in Mononuclear Cells in Multiple Sclerosis and Optic Neuritis
1995
TH1 to TH2 Shift of Cytokines in Peripheral Blood of HIV-Infected Patients Is Detectable by Reverse Transcriptase Polymerase Chain Reaction but Not by Enzyme-Linked Immunosorbent Assay Under Nonstimulated Conditions
2000
Distinct Patterns of Multiple Sclerosis Pathology Indicates Heterogeneity in Pathogenesis
1996
Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis
2010 Standout
Nuclear Factor Kb: An Oxidative Stress-Responsive Transcription Factor of Eukaryotic Cells (A Review)
1992
Augmented expression of tumour necrosis factor-α and lymphotoxin in mononuclear cells in multiple sclerosis and optic neuritis
1996
Activation of the IκBα Kinase Complex by MEKK1, a Kinase of the JNK Pathway
1997
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Development of biomarkers in multiple sclerosis
2004
Neuronal activity triggers calcium waves in hippocampal astrocyte networks
1992
A new approach for evaluating antigen-specific T cell responses to myelin antigens during the course of multiple sclerosis
2003
Accelerated Course of Experimental Autoimmune Encephalomyelitis in PD-1-Deficient Central Nervous System Myelin Mutants
2009
Transforming growth factor beta (TGF-?) in inflammation: A cause and a cure
1992
A new mathematical model for relative quantification in real-time RT-PCR
2001 Standout
US FDA-Approved Disease-Modifying Treatments for Multiple Sclerosis
2005
PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis
2006
Tumour necrosis factor alpha mRNA expression in early multiple sclerosis lesions: Correlation with demyelinating activity and oligodendrocyte pathology
2000
Complex immunomodulatory effects of interferon‐β in multiple sclerosis include the upregulation of T helper 1‐associated marker genes
2001
The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults
1996 StandoutNobel
TGF-β1 Alters APC Preference, Polarizing Islet Antigen Responses toward a Th2 Phenotype
1998
CCR1+/CCR5+ Mononuclear Phagocytes Accumulate in the Central Nervous System of Patients with Multiple Sclerosis
2001
TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease
2008
The role of TGF-β in growth, differentiation, and maturation of B lymphocytes
1999
TGF-β and immune cells: an important regulatory axis in the tumor microenvironment and progression
2010
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
2006
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
2006 StandoutNature
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Does the HIV envelope induce a chronic graft-versus-host-like disease?
1992
The pathology of primary progressive multiple sclerosis
2004
The Immunopathogenesis of Human Immunodeficiency Virus Infection
1993
Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
2000 Standout
Host factors in the pathogenesis of HIV disease
1997
CTLA4 gene polymorphism and autoimmunity
2005
Chemokines in chronic progressive neurological diseases: HTLV-1 associated myelopathy and multiple sclerosis
1999
Requirement of Caveolae Microdomains in Extracellular Signal‐Regulated Kinase and Focal Adhesion Kinase Activation Induced by Endothelin‐1 in Primary Astrocytes
1999
Cancer immunotherapy comes of age
2011 StandoutNature
Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis
2010
Control of peripheral T‐cell tolerance and autoimmunity via the CTLA‐4 and PD‐1 pathways
2008
Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy
2001
Multiple sclerosis: In situ evidence for antibody‐ and complement‐mediated demyelination
1998
Oestrogen modulates experimental autoimmune encephalomyelitis and interleukin‐17 production via programmed death 1
2008
PD-1 and PD-1 ligands: from discovery to clinical application
2007
Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension
1993 Standout
Inositol trisphosphate and calcium signalling
1993 StandoutNature
Immunopathogenic Mechanisms in Human Immunodeficiency Virus (HIV) Infection
1991
Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease
1992 StandoutNature
PD-1 Regulates Neural Damage in Oligodendroglia-Induced Inflammation
2009
Intrathecal activation of the complement system and disability in multiple sclerosis
1998
The Inhibitory Effects of Transforming Growth Factor-Beta-1 (TGF-β1) in Autoimmune Diseases
2000
Regulation by HIV Rev depends upon recognition of splice sites
1989 StandoutNobel
Elevated serum levels of IFN-γ, IL-4 and TNF-α/unelevated serum levels of IL-10 in patients with demyelinating diseases during the acute stage
1998
Cytokine producing CD8+ T cells are correlated to MRI features of tissue destruction in MS
2003
Function and Activation of NF-kappaB in the Immune System
1994 Standout
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Microarray gene expression profiling of chronic active and inactive lesions in multiple sclerosis
2004
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
2007
Down‐modulation of programmed death 1 alters regulatory T cells and promotes experimental autoimmune encephalomyelitis
2009
Genetic, immunologic, and immunohistochemical analysis of the programmed death 1/programmed death ligand 1 pathway in human systemic lupus erythematosus
2008
Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays
2000 Standout
Essential role of tumor necrosis factor‐α in the differentiation of human tonsil in vivo induced B cells capable of spontaneous and high‐rate immunoglobulin secretion
1993
Microglial Physiology: Unique Stimuli, Specialized Responses
2009
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
Expression analysis of the autosomal recessive primary microcephaly genes MCPH1 (microcephalin) and MCPH5 (ASPM, abnormal spindle-like, microcephaly associated) in human malignant gliomas
1994
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
1999 StandoutNobel
Proteasome regulation of activation-induced T cell death
1997 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination.
1995
Functional Analysis of Antigen-Specific T Lymphocytes by Serial Measurement of Gene Expression in Peripheral Blood Mononuclear Cells and Tumor Specimens
1999
Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A.
1992
Review of teriflunomide and its potential in the treatment of multiple sclerosis
2009
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.
1995
Lack of a role for transforming growth factor-β in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation
2001 StandoutNobel
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
2008 StandoutNobel
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Clonal Expansions of Cd8+ T Cells Dominate the T Cell Infiltrate in Active Multiple Sclerosis Lesions as Shown by Micromanipulation and Single Cell Polymerase Chain Reaction
2000
IMMUNOLOGY OF MULTIPLE SCLEROSIS
2005 Standout
Resistance to Replication of Human Immunodeficiency Virus Challenge in SCID-Hu Mice Engrafted with Peripheral Blood Mononuclear Cells of Nonprogressors Is Mediated by CD8+T Cells and Associated with a Proliferative Response to p24 Antigen
2000
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity
2000 StandoutNobel
Transforming growth factor-beta 1 (TGF-beta1) promotes IL-2 mRNA expression through the up-regulation of NF-kappaB, AP-1 and NF-AT in EL4 cells.
1998
TH1 to TH2 Shift of Cytokines in Peripheral Blood of HIV-Infected Patients Is Detectable by Reverse Transcriptase Polymerase Chain Reaction but Not by Enzyme-Linked Immunosorbent Assay Under Nonstimulated Conditions
2000
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer.
1994 StandoutNobel
Transforming Growth Factor-β Pathway Serves as a Primary Tumor Suppressor in CD8+ T Cell Tumorigenesis
2004
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
1995 StandoutNobel
Comparison of injection site pain and injection site reactions in relapsing-remitting multiple sclerosis patients treated with interferon beta-1a or 1b
2007
Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections.
1994 StandoutNobel
Multifactorial Nature of Human Immunodeficiency Virus Disease: Implications for Therapy
1993 Science
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
1993 StandoutNobel
Transforming Growth Factor β and Cyclosporin A Inhibit the Inducible Activity of the Interleukin-2 Gene in T Cells Through a Noncanonical Octamer-Binding Site
1993
Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline
2010 StandoutNobel
TRANSFORMING GROWTH FACTOR-β REGULATION OF IMMUNE RESPONSES
2005 Standout
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
Differential Role of Programmed Death-Ligand 1 and Programmed Death-Ligand 2 in Regulating the Susceptibility and Chronic Progression of Experimental Autoimmune Encephalomyelitis
2006
Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors.
1994
Association between clinical disease activity and Epstein–Barr virus reactivation in MS
2000
Interleukin‐12 and Perforin mRNA Expression is Augmented in Blood Mononuclear Cells in Multiple Sclerosis
1998
A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B.
1994
The pathology of primary progressive multiple sclerosis
2002
Existence of nitric oxide synthase in rat hippocampal pyramidal cells.
1994 StandoutNobel
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Apoptosis in AIDS
1993 StandoutScienceNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
PD-1 and Its Ligands in Tolerance and Immunity
2008 Standout
The Human T Cell Response to Myelin Oligodendrocyte Glycoprotein: A Multiple Sclerosis Family-Based Study
2002
Chemical Glycoproteomics
2016 StandoutNobel
Human Plasma N-Glycoproteome Analysis by Immunoaffinity Subtraction, Hydrazide Chemistry, and Mass Spectrometry
2005
Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1
1994 StandoutNobel
Works of Peter Rieckmann being referenced
Cardiotoxicity and other adverse events associated with mitoxantrone treatment for MS
2010
CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation
2002
CTLA4 exon 1 dimorphism is associated with primary progressive multiple sclerosis
2002
A PD‐1 polymorphism is associated with disease progression in multiple sclerosis
2005
Emerging oral therapies for multiple sclerosis
2007
Cell-mediated immune response of macaques immunized with low doses of simian immunodeficiency virus (SIV)
1996
Monocyte/macrophage differentiation in early multiple sclerosis lesions
1995
Siponimod for patients with relapsing-remitting multiple sclerosis (BOLD): an adaptive, dose-ranging, randomised, phase 2 study
2013
A vasoactive peptide, endothelin-3, is produced by and specifically binds to primary astrocytes
1991
Regulation of human endogenous retrovirus W protein expression by herpes simplex virus type 1: Implications for multiple sclerosis
2006
Quantification of cytokine mRNA expression by RT PCR in samples of previously frozen blood
1997
Impact of the Asp299Gly polymorphism in the toll-like receptor 4 (tlr-4) gene on disease course of multiple sclerosis
2005
Inflammation in multiple sclerosis: the good, the bad, and the complex
2002
Tumor necrosis factor‐α messenger RNA expression in patients with relapsing‐remitting multiple sclerosis is associated with disease activity
1995
Soluble adhesion molecules (sVCAM‐1 and sICAM‐1) in cerebrospinal fluid and serum correlate with MRI activity in multiple sclerosis
1997
Managing the Adverse Effects of Interferon-?? Therapy in Multiple Sclerosis
2000
Synergistic immunomodulatory effects of interferon‐β1b and the phosphodiesterase inhibitor pentoxifylline in patients with relapsing‐remitting multiple sclerosis
1998
Identification of macrophage populations expressing tumor necrosis factor-α mRNA in acute multiple sclerosis
1998
Ultrasound derived imaging and quantification of cell adhesion molecules in experimental autoimmune encephalomyelitis (EAE) by Sensitive Particle Acoustic Quantification (SPAQ)
2005
Semi-quantitative analysis of cytokine gene expression in blood and cerebrospinal fluid cells by reverse transcriptase polymerase chain reaction
1995
Microglial/macrophage expression of interleukin 10 in human glioblastomas
1999
Plasma exchange for severe optic neuritis
2004
Endothelins, peptides with potent vasoactive properties, are produced by human macrophages.
1990
Potent stimulation of monocytic endothelin-1 production by HIV-1 glycoprotein 120.
1993
Induction of nuclear factor-kappa B and the human immunodeficiency virus long terminal repeat by okadaic acid, a specific inhibitor of phosphatases 1 and 2A.
1990
IL-6 and tumor necrosis factor-alpha. Autocrine and paracrine cytokines involved in B cell function.
1991
Activated B lymphocytes from human immunodeficiency virus-infected individuals induce virus expression in infected T cells and a promonocytic cell line, U1.
1991
Circulating forms of ICAM-3 (cICAM-3). Elevated levels in autoimmune diseases and lack of association with cICAM-1.
1995
Recombinant gp120 specifically enhances tumor necrosis factor-alpha production and Ig secretion in B lymphocytes from HIV-infected individuals but not from seronegative donors
1991
Cytokine mRNA levels in mononuclear blood cells from patients with multiple sclerosis
1994
Basic and escalating immunomodulatory treatments in multiple sclerosis: Current therapeutic recommendations
2008
Transforming growth factor-beta suppresses human B lymphocyte Ig production by inhibiting synthesis and the switch from the membrane form to the secreted form of Ig mRNA.
1991