Citation Impact
Citing Papers
Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry
2008 Science
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
Polo-Like Kinase Cdc5 Controls the Local Activation of Rho1 to Promote Cytokinesis
2006 Science
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
The PITSLRE/CDK11 p58 protein kinase promotes centrosome maturation and bipolar spindle formation
2006
Linkage Map ofEscherichia coliK-12, Edition 10: The Traditional Map
1998
Whole-genome resequencing reveals loci under selection during chicken domestication
2010 StandoutNature
Towards the computational design of protein post-translational regulation
2015
Evolution of a designed retro-aldolase leads to complete active site remodeling
2013 StandoutNobel
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Specificity in Signal Transduction
2004
Getting in and out of mitosis with Polo-like kinase-1
2005
The Tuberous Sclerosis Complex
2006 Standout
How enzymes adapt: lessons from directed evolution
2001 StandoutNobel
Synthesis of neurotensin(8–13)–phosphopeptide heterodimers via click chemistry
2010
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Random-priming in vitro recombination: An effective tool for directed evolution
1998 StandoutNobel
Three-dimensional cluster analysis identifies interfaces and functional residue clusters in proteins11Edited by J. Thornton
2001
ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules
2016 Standout
Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner
2005
Protein Dynamics in a Family of Laboratory Evolved Thermophilic Enzymes
2003 StandoutNobel
Polo on the Rise—from Mitotic Entry to Cytokinesis with Plk1
2008
Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS
2000 StandoutNature
Targeting protein–protein interactions for cancer therapy
2005
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
When Less Is More: Gene Loss as an Engine of Evolutionary Change
1999
Emerging cancer therapeutic opportunities by inhibiting mitotic kinases
2008
Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase
2010 StandoutNobel
The yeast chromatin remodeler Rsc1-RSC complex is required for transcriptional activation of autophagy-related genes and inhibition of the TORC1 pathway in response to nitrogen starvation
2015 StandoutNobel
Targeting cancer with small molecule kinase inhibitors
2008 Standout
Molecular evolution by staggered extension process (StEP) in vitro recombination
1998 StandoutNobel
Directed evolution of enzyme catalysts
1997 StandoutNobel
Directed evolution of industrial enzymes
1999 StandoutNobel
Gout
2016 Standout
The Small-Molecule Inhibitor BI 2536 Reveals Novel Insights into Mitotic Roles of Polo-like Kinase 1
2007
The road less traveled: modulating signal transduction enzymes by inhibiting their protein–protein interactions
2009
Dynamic interactions of proteins in complex networks: a more structured view
2009
Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase
2016 StandoutNobel
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
Tyrosine Nitration Impairs Mammalian Aldolase A Activity
2004
Chk2 Oligomerization Studied by Phosphopeptide Ligation
2008 StandoutNobel
Non-ATP competitive protein kinase inhibitors as anti-tumor therapeutics
2009
Polo-like kinases and the orchestration of cell division
2004
The COG database: a tool for genome-scale analysis of protein functions and evolution
2000 Standout
VISA Is an Adapter Protein Required for Virus-Triggered IFN-β Signaling
2005 Standout
Structural and functional analysis of aldolase B mutants related to hereditary fructose intolerance
2002
Plx1 is required for chromosomal DNA replication under stressful conditions
2008
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Phosphorylation of Chs2p regulates interaction with COPII
2013 StandoutNobel
Paul Ehrlich's magic bullet concept: 100 years of progress
2008 Standout
Targeting DNA topoisomerase II in cancer chemotherapy
2009 Standout
Hypermutagenic PCR Involving All Four Transitions and a Sizeable Proportion of Transversions
1996
Molecular aspects of fructose metabolism and metabolic disease
2021
Human DNA Damage Checkpoint Protein hRAD9 Is a 3′ to 5′ Exonuclease
2000 StandoutNobel
Targeting polo-like kinase 1 for cancer therapy
2006
Inhibition of Polo-like Kinase 1 by Blocking Polo-Box Domain-Dependent Protein-Protein Interactions
2008
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
Uric Acid: A Danger Signal From the RNA World That May Have a Role in the Epidemic of Obesity, Metabolic Syndrome, and Cardiorenal Disease: Evolutionary Considerations
2011
Inflammation in obesity, diabetes, and related disorders
2022 Standout
The Yeast Tor Signaling Pathway Is Involved in G2/M Transition via Polo-Kinase
2008 StandoutNobel
The spindle-assembly checkpoint in space and time
2007 Standout
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Polo-Like Kinase 1 Is Essential for Early Embryonic Development and Tumor Suppression
2008
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Functions of the gene products of Escherichia coli
1993
Tryptophan Phosphorescence Study of Enzyme Flexibility and Unfolding in Laboratory-Evolved Thermostable Esterases
2000 StandoutNobel
Independent modulation of the kinase and polo-box activities of Cdc5 protein unravels unique roles in the maintenance of genome stability
2011
The RSC chromatin-remodeling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the Cdc14 phosphatase
2010
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Directed evolution of a thermostable esterase
1998 StandoutNobel
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
Self-assembly–based posttranslational protein oscillators
2020 StandoutNobel
Comparative conservation analysis of the human mitotic phosphoproteome
2008
The Complete Genome Sequence of Escherichia coli K-12
1997 StandoutScience
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
A Genomic Perspective on Protein Families
1997 StandoutScience
Enzyme engineering reaches the boiling point
1998 StandoutNobel
Tor Directly Controls the Atg1 Kinase Complex To Regulate Autophagy
2009 StandoutNobel
Works of Peter Rellos being referenced
Two promoters control the aroH gene of Escherichia coli
1991
Polymerase Chain Reaction-Based Random Mutagenesis: Production and Characterization of Thermostable Mutants of Zymomonas mobilis Alcohol Dehydrogenase-2
1994
Expression, Purification, and Characterization of Natural Mutants of Human Aldolase B
2000
Thermostable Variants ofZymomonas mobilisAlcohol Dehydrogenase Obtained Using PCR-Mediated Random Mutagenesis
1998
The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain
2003
Alteration of substrate specificity by a naturally-occurring aldolase B mutation (Ala337→Val) in fructose intolerance
1999
Hereditary fructose intolerance.
1998