Citation Impact
Citing Papers
Functionally specialized junctions between endothelial cells of lymphatic vessels
2007 Standout
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
2001 Standout
The Leukotriene C4 Transporter MRP1 Regulates CCL19 (MIP-3β, ELC)–Dependent Mobilization of Dendritic Cells to Lymph Nodes
2000
Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3
2015
Targeting JAK kinase in solid tumors: emerging opportunities and challenges
2015
Atopic Dermatitis
2008 Standout
Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase
2014
Selectivity of Recombinant Human Leukotriene D4, Leukotriene B4, and Lipoxin A4 Receptors with Aspirin-Triggered 15-epi-LXA4 and Regulation of Vascular and Inflammatory Responses
2001
Δ12-Prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes
2005
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
2005 Standout
Evaluation of Cetirizine in Patients with Allergic Rhinitis and Perennial Asthma
1996
Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework
2014 Standout
Pharmacological Characterization of MK-7246, a Potent and Selective CRTH2 (Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type 2 Cells) Antagonist
2010
LEUKOTRIENES, LEUKOTRIENE RECEPTOR ANTAGONISTS AND LEUKOTRIENE SYNTHESIS INHIBITORS IN ASTHMA: AN UPDATE. PART I: SYNTHESIS, RECEPTORS AND ROLE OF LEUKOTRIENES IN ASTHMA
1999
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Active immunization against cancer with dendritic cells: The near future
2001 StandoutNobel
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
2019 Standout
Long‐term treatment with cetirizine of infants with atopic dermatitis: A multi‐country, double‐blind, randomized, placebo‐controlled trial (the ETAC™trial) over 18 months
2002
International Union of Pharmacology XXXVII. Nomenclature for Leukotriene and Lipoxin Receptors
2003
Dendritic cell migration to lymph nodes: cytokines, chemokines, and lipid mediators
2001
Cetirizine
2004
Cellular inflammatory responses during immediate, developing, and established late-phase allergic cutaneous reactions: Effects of cetirizine
1997
The use of dendritic cells in cancer immunotherapy
2003 StandoutNobel
Novel Docosatrienes and 17S-Resolvins Generated from Docosahexaenoic Acid in Murine Brain, Human Blood, and Glial Cells
2003 Standout
The next generation of PDE4 inhibitors
2001
Variations among non-sedating antihistamines: are there real differences?
1999
Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitors
2016
A double‐blind, single‐dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine‐induced wheal and flare response for 24 h in healthy male subjects
1999
Inflammation and tumor progression: signaling pathways and targeted intervention
2021 Standout
CC Chemokine Receptors and Chronic Inflammation—Therapeutic Opportunities and Pharmacological Challenges
2013
A placebo-controlled, dose-ranging study of montelukast, a cysteinyl leukotriene–receptor antagonist
1998
Allergic Rhinitis and Its Impact on Asthma
2001 Standout
The JAK/STAT signaling pathway: from bench to clinic
2021 Standout
JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects
2017
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
2018 Standout
Cetirizine in patients with seasonal rhinitis and concomitant asthma: prospective, randomized, placebo-controlled trial
1995
Polyketide biosynthesis: a millennium review
2001 Standout
Cetirizine inhibits the in vitro and ex vivo chemotactic response of T lymphocytes and monocytes
1995
Identification, Molecular Cloning, Expression, and Characterization of a Cysteinyl Leukotriene Receptor
1999
Global strategy for asthma management and prevention: GINA executive summary
2007 Standout
Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility
2013 Nature
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
2003 Standout
Ulcerative colitis
2020 Standout
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
1995 Standout
The expanding superfamily of phospholipase A2 enzymes: classification and characterization
2000 Standout
Points of control in inflammation
2002 StandoutNature
The PI3K Pathway in Human Disease
2017 Standout
The comparison of the efficacy and safety of cetirizine, oxatomide, ketotifen, and a placebo for the treatment of childhood perennial allergic rhinitis
2002
Asthma Therapy with Agents Preventing Leukotriene Synthesis or Action
1999
8-Epi-PGF2 alpha, a novel noncyclooxygenase-derived prostaglandin, constricts airways in vitro.
1996
The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I
1995 Standout
The role of the basophil in allergic inflammation
1995
Ultra-Rapid Cardiotoxicity of the Hepatitis C Virus Protease Inhibitor BILN 2061 in the Urokinase-Type Plasminogen Activator Mouse
2007
Upadacitinib in adults with moderate to severe atopic dermatitis: 16-week results from a randomized, placebo-controlled trial
2019
Does the PI3K pathway promote or antagonize regulatory T cell development and function?
2012
Mast cells in the development of adaptive immune responses
2005 Standout
Alternative activation of macrophages
2003 Standout
Mast Cells as Drivers of Disease and Therapeutic Targets
2017
Mast cell and eosinophil surface receptors as targets for anti-allergic therapy
2016
Asthma
2000 Standout
Pharmacological Characterization of Leukotriene Receptors
2000
Effects of LTD 4 on Human Airway Smooth Muscle Cell Proliferation, Matrix Expression, and Contraction In Vitro : Differential Sensitivity to Cysteinyl Leukotriene Receptor Antagonists
1998
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
2017 Standout
Fluorine in medicinal chemistry
2007 Standout
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
2012 Standout
Prostanoid Receptors: Structures, Properties, and Functions
1999 Standout
Discovery and Development of Janus Kinase (JAK) Inhibitors for Inflammatory Diseases
2014
Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene.
1994
Abrocitinib for the treatment of atopic dermatitis
2020
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Coordinative Alignment in the Pores of MOFs for the Structural Determination of N-, S-, and P-Containing Organic Compounds Including Complex Chiral Molecules
2019 StandoutNobel
Cyclooxygenases: Structural, Cellular, and Molecular Biology
2000 Standout
Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations
2015 Standout
Orally active PDE4 inhibitors with therapeutic potential
2004
Plasminogen Activators, Tissue Degradation, and Cancer
1985 Standout
Allergic factors associated with the development of asthma and the influence of cetirizine in a double‐blind, randomised, placebo‐controlled trial: First results of ETA®
1998
Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore
2010 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Inflammation and Cellular Immune Responses in Abdominal Aortic Aneurysms
2006 Standout
Human FcERI-IgG and humanized anti-IgE monoclonal antibody MaE11 block passive sensitization of human and rhesus monkey lung
1994
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors
2013
Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype.
1993
Control of foreign Ag‐specific Ab responses by Treg and Tfr
2020 StandoutNobel
A Matching-Adjusted Indirect Comparison of Upadacitinib Versus Tofacitinib in Adults with Moderate-to-Severe Rheumatoid Arthritis
2020
The Biological Basis for Cardiac Repair After Myocardial Infarction
2016 Standout
Microsomal glutathione S-transferase is the predominant leukotriene C4 binding site in cellular membranes.
1994
Tailoring the volatility and stability of oligopeptides
2017 StandoutNobel
International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes.
1994 Standout
Small Molecules Drive Big Improvements in Immuno‐Oncology Therapies
2017
Microglial M1/M2 polarization and metabolic states
2015 Standout
Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor
2001
Purification and characterization of the biliary plasminogen activator bilokinase.
1983
Prostaglandins and Inflammation
2011 Standout
Towards a small animal model for hepatitis C
2009 StandoutNobel
Synthesis and Structure−Activity Relationships of Carboxylated Chalcones: A Novel Series of CysLT1 (LTD4) Receptor Antagonists
1997
Exposure–Response Analyses of Upadacitinib Efficacy and Safety in Phase II and III Studies to Support Benefit–Risk Assessment in Rheumatoid Arthritis
2019
Rhodium(III)‐Catalyzed Regioselective Direct C‐2 Alkenylation of Indoles Assisted by the Removable N‐(2‐Pyrimidyl) Group
2014
Prostaglandin D2Inhibits Inducible Nitric Oxide Synthase Expression in Rat Vascular Smooth Muscle Cells
1998
Prescribed drugs containing nitrogen heterocycles: an overview
2020 Standout
Janus kinase inhibitors for the treatment of inflammatory bowel diseases: developments from phase I and phase II clinical trials
2018
Works of Peter Norman being referenced
Effect of H1 receptor blockade on the early and late response to cutaneous allergen challenge.
1992
Spleen tyrosine kinase inhibitors: a review of the patent literature 2010 – 2013
2014
Characterisation of the peptido-leukotriene receptor PL2 on the ferret spleen strip
1993
Selective PI3Kδ inhibitors, a review of the patent literature
2011
Evaluation of WO2011134971, chiral 1,6-napthyridine Syk kinase inhibitors
2012
BAY u9773, a novel antagonist of cysteinyl-leukotrienes with activity against two receptor subtypes
1994
DP2receptor antagonists in development
2010
Selective JAK1 inhibitor and selective Tyk2 inhibitor patents
2012
BAY u3405, a potent and selective thromboxane A2 receptor antagonist on airway smooth muscle in vitro
1991
The binding of [3H]leukotriene C4 to guinea-pig lung membranes. The lack of correlation of LTC4 functional activity with binding affinity
1987
Autoradiographic localization of leukotriene C4 and D4 binding sites in guinea-pig lung
1988
Characterisation of receptors mediating the contractile effects of prostanoids in guinea-pig and human airways
1988
The inhibition of [3H]leukotriene D4 binding to guinea-pig lung membranes. The correlation of binding affinity with activity on the guinea-pig ileum
1990
A dual CCR2/CCR5 chemokine antagonist, BMS-813160?
2011
Non-Enzymatic Lysis of Fibrin s by Bile.
1960
PDE4 inhibitors 2001. Patent and literature activity 2000 - September 2001
2002
Leukotriene receptors and their selective antagonists.
1994
A second cysteinyl leukotriene receptor in human lung.
1992
Update on the status of DP2 receptor antagonists; from proof of concept through clinical failures to promising new drugs
2013
PDE4 inhibitors: sustained patenting activity as leading drugs near the market
2000
Selective JAK inhibitors in development for rheumatoid arthritis
2014
A new structural analogue antagonist of peptido-leukotrienes. The discovery of bay x7195
1993
Novel Protease Inhibitors.
2002
Characterisation of leukotriene receptors on rat lung strip
1994