Citation Impact
Citing Papers
Mutational Analysis of the Tyrosine Phosphatome in Colorectal Cancers
2004 Science
Loss of Fhit is frequent in stage I non-small cell lung cancer and in the lungs of chronic smokers.
1999
Precise localization of theFHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affectFHIT transcription in tumor cell lines
1997
Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression.
1999
Loss of FHIT function in lung cancer and preinvasive bronchial lesions.
1998
Mutation analysis of hypoxia-inducible factors HIF1A and HIF2A in renal cell carcinoma.
2009 StandoutNobel
Genome-wide screening of copy number alterations and LOH events in renal cell carcinomas and integration with gene expression profile
2008
Common fragile sites
2003
ATR Regulates Fragile Site Stability
2002
Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome
2003 StandoutNature
The von Hippel–Lindau Tumor Suppressor Gene
2001 StandoutNobel
The neural control of micturition
2008 Standout
Characterization of the Human TESTIN Gene Localized in the FRA7G Region at 7q31.2
2000
Molecular basis of the VHL hereditary cancer syndrome
2002 StandoutNobel
Major role for a 3p21 region and lack of involvement of the t(3;8) breakpoint region in the development of renal cell carcinoma suggested by loss of heterozygosity analysis
1996
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Renal-Cell Carcinoma
1996 Standout
Novel Vertebrate Genes and Putative Regulatory Elements Identified at Kidney Disease and NR2E1/fierce Loci
2002 StandoutNobel
ATM and related protein kinases: safeguarding genome integrity
2003 Standout
Associative Versus Dissociative Mechanisms of Phosphate Monoester Hydrolysis: On the Interpretation of Activation Entropies
2008 StandoutNobel
The FHIT Gene, Spanning the Chromosome 3p14.2 Fragile Site and Renal Carcinoma–Associated t(3;8) Breakpoint, Is Abnormal in Digestive Tract Cancers
1996 Standout
Regulation of the G2/M transition by p53
2001 Standout
Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
2005 Standout
The pVHL-associated SCF ubiquitin ligase complex: Molecular genetic analysis of elongin B and C, Rbx1 and HIF-1α in renal cell carcinoma
2001 StandoutNobel
Nickel carcinogenesis
2003 Standout
HIF hydroxylation and the mammalian oxygen-sensing pathway
2003 StandoutNobel
Protein Expression and Functional Analysis of the FHIT Gene in Human Tumor Cells
1998
The FHIT Gene at 3p14.2 Is Abnormal in Lung Cancer
1996
Epstein–Barr virus: 40 years on
2004 Standout
A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function
2008 Standout
INTRAVESICAL CAPSAICIN AND RESINIFERATOXIN THERAPY: SPICING UP THE WAYS TO TREAT THE OVERACTIVE BLADDER
1999
Fragile and unstable chromosomes in cancer: causes and consequences
2001
Nucleoside triphosphate-binding proteins: different scaffolds to achieve phosphoryl transfer
1999
Loss of expression of theDRR 1 gene at chromosomal segment 3p21.1 in renal cell carcinoma
2000
Tobacco Smoke Carcinogens and Lung Cancer
1999 Standout
Electrostatic Basis for Bioenergetics
2004 StandoutNobel
New cancer targets emerging from studies of the Von Hippel‐Lindau tumor suppressor protein
2010 StandoutNobel
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
2005 StandoutNature
A census of human cancer genes
2004 Standout
Transient Receptor Potential Cation Channels in Disease
2007 Standout
Are Mixed Explicit/Implicit Solvation Models Reliable for Studying Phosphate Hydrolysis? A Comparative Study of Continuum, Explicit and Mixed Solvation Models
2009 StandoutNobel
Genetic and epigenetic changes in nasopharyngeal carcinoma
2002
Sexual function in spinal cord lesioned men
2001
Why nature really chose phosphate
2013 StandoutNobel
MUTATION OF THEVHL GENE IS ASSOCIATED EXCLUSIVELY WITH THE DEVELOPMENT OF NON-PAPILLARY RENAL CELL CARCINOMAS
1996
Loss of heterozygosity on chromosome arm 3p in nasopharyngeal carcinoma
1996
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
Alterations on chromosome 3 in endemic and nonendemic nasopharyngeal carcinoma
2000
Targeting Recovery: Priorities of the Spinal Cord-Injured Population
2004 Standout
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
Inactivation of the von Hippel–Lindau ( VHL ) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: Evidence for a VHL ‐independent pathway in clear cell renal tumourigenesis
1998
MCG10, a Novel p53 Target Gene That Encodes a KH Domain RNA-Binding Protein, Is Capable of Inducing Apoptosis and Cell Cycle Arrest in G2-M
2000
The Enigmatic Epidemiology of Nasopharyngeal Carcinoma
2006 Standout
On the Mechanism of Hydrolysis of Phosphate Monoesters Dianions in Solutions and Proteins
2006 StandoutNobel
HIF hydroxylation and the mammalian oxygen-sensing pathway
2003 StandoutNobel
Dineopentyl Phosphate Hydrolysis: Evidence for Stepwise Water Attack
2008 StandoutNobel
Transcriptional control of human p53-regulated genes
2008 Standout
THE ROLE OF THE FHIT/FRA3B LOCUS IN CANCER
1998
High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints.
2000 Standout
Addressing Open Questions about Phosphate Hydrolysis Pathways by Careful Free Energy Mapping
2012 StandoutNobel
Progress in Ab Initio QM/MM Free-Energy Simulations of Electrostatic Energies in Proteins: Accelerated QM/MM Studies of pKa, Redox Reactions and Solvation Free Energies
2008 StandoutNobel
The Vanilloid Receptor: A Molecular Gateway to the Pain Pathway
2001 StandoutNobel
Replacement of Fhit in cancer cells suppresses tumorigenicity
1997
Quantifying the Mechanism of Phosphate Monoester Hydrolysis in Aqueous Solution by Evaluating the Relevant Ab Initio QM/MM Free-Energy Surfaces
2013 StandoutNobel
Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their Significance in Germ Cell Movement in the Seminiferous Epithelium during Spermatogenesis
2004 Standout
Genetic, biochemical, and crystallographic characterization of Fhit–substrate complexes as the active signaling form of Fhit
1998
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
2004 Standout
Molecular pathogenesis of the von Hippel-Lindau hereditary cancer syndrome: implications for oxygen sensing.
2001 StandoutNobel
On the Interpretation of the Observed Linear Free Energy Relationship in Phosphate Hydrolysis: A Thorough Computational Study of Phosphate Diester Hydrolysis in Solution
2008 StandoutNobel
Role ofVHLGene Mutation in Human Cancer
2004 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Sequence conservation at human and mouse orthologous common fragile regions, FRA3B / FHIT and Fra14A2 / Fhit
2001
The epithelial–mesenchymal transition: new insights in signaling, development, and disease
2006 Standout
Intravesical Instillation of Capsaicin in Urology: A Review of the Literature
1999
Works of Peter McCue being referenced
Structure and expression of the human FHIT gene in normal and tumor cells.
1997
Common regions of deletion in chromosome regions 3p12 and 3p14.2 in primary clear cell renal carcinomas.
1994
Loss of heterozygosity at the familial RCC t(3;8) locus in most clear cell renal carcinomas.
1995
Quantitative Testicular Biopsy in Spinal Cord Injured Men: Comparison to Fertile Controls
1991
EFFECT OF INTRAVESICAL CAPSAICIN AND VEHICLE ON BLADDER INTEGRITY IN CONTROL AND SPINAL CORD INJURED RATS
1998