Standout Papers
Citation Impact
Citing Papers
Prospective identification of tumorigenic breast cancer cells
2003 Standout
Identification of the haematopoietic stem cell niche and control of the niche size
2003 StandoutNature
The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor
2004
Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment
2002
Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk?
2004
Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
1996 StandoutNature
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Loss of γ-Secretase Function Impairs Endocytosis of Lipoprotein Particles and Membrane Cholesterol Homeostasis
2008
Thrombopoietin/MPL Signaling Regulates Hematopoietic Stem Cell Quiescence and Interaction with the Osteoblastic Niche
2007
Osteoblastic cells regulate the haematopoietic stem cell niche
2003 StandoutNature
Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation
1997
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
FcR γ chain deletion results in pleiotrophic effector cell defects
1994
Cells on chips
2006 StandoutNature
Molecular Events Mediating T Cell Activation
1990
Human autoimmune lymphoproliferative syndrome, a defect in the apoptosis-inducing Fas receptor: A lesson from the mouse model
1998
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
2001 StandoutNobel
Tyrosine Phosphorylation of the β-Amyloid Precursor Protein Cytoplasmic Tail Promotes Interaction with Shc
2002
The CD2 antigen associates with the T-cell antigen receptor CD3 antigen complex on the surface of human T lymphocytes
1989 Nature
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Calcium dyshomeostasis and intracellular signalling in alzheimer's disease
2002
Assessment of telomere length and factors that contribute to its stability
2003
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Hepatitis C virus–specific T-cell reactivity during interferon and ribavirin treatment in chronic hepatitis C
2000
TWEAK, a New Secreted Ligand in the Tumor Necrosis Factor Family That Weakly Induces Apoptosis
1997
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
1999 StandoutNature
A role for Wnt signalling in self-renewal of haematopoietic stem cells
2003 StandoutNature
Ultra-high-throughput screening based on cell-surface display and fluorescence-activated cell sorting for the identification of novel biocatalysts
2004
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
2009 StandoutNatureNobel
The ikaros gene is required for the development of all lymphoid lineages
1994
Human Natural Killer Cells: Origin, Clonality, Specificity, and Receptors
1993
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
1995 StandoutNature
Identification of a Fetal Hematopoietic Precursor with B Cell, T Cell, and Macrophage Potential
1998
γ-Secretase-mediated proteolysis in cell-surface-receptor signalling
2002
Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function
2000
Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory
2003
Role of Lymphocyte Adhesion Receptors in Transient Interactions and Cell Locomotion
1991
Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
2009 StandoutNature
The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
1994
Learning and Memory Deficits in Notch Mutant Mice
2003 StandoutNobel
Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis
1995 Nature
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
2000 StandoutNature
Development of peripheral lymphoid organs and natural killer cells depends on the helix–loop–helix inhibitor Id2
1999 Nature
The Hallmarks of Aging
2013 Standout
Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role
2008
Effect of prolonged freezing of semen on exosome recovery and biologic activity
2017
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Sorting through the Cell Biology of Alzheimer's Disease: Intracellular Pathways to Pathogenesis
2006
Processing of β-Amyloid Precursor-like Protein-1 and -2 by γ-Secretase Regulates Transcription
2002
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
The gastrointestinal tract stem cell niche
2006
Intestinal macrophages and response to microbial encroachment
2010
An Integral Membrane Green Fluorescent Protein Marker, Us9-GFP, Is Quantitatively Retained in Cells during Propidium Iodide-Based Cell Cycle Analysis by Flow Cytometry
1999
YOPRO-1 permits cytofluorometric analysis of programmed cell death (apoptosis) without interfering with cell viability
1995
The β‐Amyloid Precursor Protein (APP) and Alzheimer's Disease: Does the Tail Wag the Dog?
2002
Angiogenesis as a therapeutic target
2005 StandoutNature
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein
1995 StandoutNatureNobel
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Hematopoietic Stem Cell Quiescence Maintained by p21 cip1/waf1
2000 Science
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
The JNK Pathway Regulates the In Vivo Deletion of Immature CD4+CD8+ Thymocytes
1998
Marker-specific sorting of rare cells using dielectrophoresis
2005
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
A role for E2F1 in the induction of ARF, p53, and apoptosis during thymic negative selection.
1999
Intrinsic Human Immunodeficiency Virus Type 1 Resistance of Hematopoietic Stem Cells Despite Coreceptor Expression
1999
Cutting Edge: Lymphocyte Inhibitor of TRAIL (TNF-Related Apoptosis-Inducing Ligand): A New Receptor Protecting Lymphocytes from the Death Ligand TRAIL
1998
Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell
1996 StandoutScience
CTLA4 mediates antigen-specific apoptosis of human T cells.
1995
DNA Synthesis and Neuronal Apoptosis Caused by Familial Alzheimer Disease Mutants of the Amyloid Precursor Protein Are Mediated by the p21 Activated Kinase PAK3
2003
Quantum Dot-Based Multiplexed Fluorescence Resonance Energy Transfer
2005 StandoutNobel
The vitronectin receptor serves as an accessory molecule for the activation of a subset of gamma/delta T cells.
1991
Cellular Interactions in Thymocyte Development
1996
Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3
1997
Death Receptors: Signaling and Modulation
1998 StandoutScience
Multilineage gene expression precedes commitment in the hemopoietic system.
1997
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
Tissue Engineering--Current Challenges and Expanding Opportunities
2002 StandoutScience
CD1d-Restricted and TCR-Mediated Activation of V α 14 NKT Cells by Glycosylceramides
1997 StandoutScience
C‐terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase‐3β expression
2003
Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections.
1994 StandoutNobel
Persistence of human multilineage, self-renewing lymphohematopoietic stem cells in chimeric sheep
1993
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Natural killer cell receptors specific for major histocompatibility complex class I molecules.
1995
PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine
2001 StandoutNobel
Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin
1998
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Essential requirement of an invariant V alpha 14 T cell antigen receptor expression in the development of natural killer T cells.
1996
LARD: A new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing
1997
A Cell Culture Model for T Lymphocyte Clonal Anergy
1990 StandoutScience
Abnormal Development of Intestinal Intraepithelial Lymphocytes and Peripheral Natural Killer Cells in Mice Lacking the IL-2 Receptor β Chain
1997
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
2000 StandoutNature
Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): a new receptor protecting lymphocytes from the death ligand TRAIL.
1998
Diverse CD81 Proteins Support Hepatitis C Virus Infection
2006 StandoutNobel
Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals
2003
Enhancement of Antitumor Immunity by CTLA-4 Blockade
1996 StandoutScienceNobel
Incubation of murine bone marrow cells in hypoxia ensures the maintenance of marrow‐repopulating ability together with the expansion of committed progenitors
2000
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Phenotypic and Functional Changes Induced at the Clonal Level in Hematopoietic Stem Cells After 5-Fluorouracil Treatment
1997
Exosomes: Mechanisms of Uptake
2015
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
TRANSCRIPTIONAL REGULATION OF T LYMPHOCYTE DEVELOPMENT AND FUNCTION
1999
Works of Peter Lopez being referenced
A simple fluorescence method for surface antigen phenotyping of lymphocytes undergoing DNA fragmentation
1992
Commercial high speed machines open new opportunities in high throughput flow cytometry (HTFC)
2000
Jun NH2-terminal Kinase (JNK) Interacting Protein 1 (JIP1) Binds the Cytoplasmic Domain of the Alzheimer's β-Amyloid Precursor Protein (APP)
2002
Fluorescence-activated cell sorting of transfected cells
1997 StandoutNobel
Autosomal Recessive Hypercholesterolemia Protein Interacts with and Regulates the Cell Surface Level of Alzheimer's Amyloid β Precursor Protein
2003
A population of early fetal thymocytes expressing FcγRIIIII contains precursors of T lymphocytes and natural killer cells
1992
Inhibition of immune functions by antiviral drugs.
1991
Fas Modulation of Apoptosis during Negative Selection of Thymocytes
1996
Functional Isolation and Characterization of Human Hematopoietic Stem Cells
1995 Science
Recombinant Extracellular Domains of Tetraspanin Proteins Are Potent Inhibitors of the Infection of Macrophages by Human Immunodeficiency Virus Type 1
2006
The γ-secretase-generated intracellular domain of β-amyloid precursor protein binds Numb and inhibits Notch signaling
2002
Interdependence of CD3-Ti and CD2 activation pathways in human T lymphocytes.
1988
Mechanisms of Gastrointestinal CD4+T-Cell Depletion during Acuteand Early Human Immunodeficiency Virus Type 1 Infection
2006