Citation Impact
Citing Papers
Computational protein design enables a novel one-carbon assimilation pathway
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Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
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Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
2002
Chromatin remodeling and transcription
1997
Eukaryotic Transcription: An Interlaced Network of Transcription Factors and Chromatin-Modifying Machines
1998
Structure of the Histone Acetyltransferase Hat1
1998 StandoutNobel
Expression of the SV40 promoter in fission yeast: Identification and characterization of an AP-1-like factor
1988 StandoutNobel
Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complexes, are also required for transcriptional function in vivo
1998
Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A
1997
p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase
1995 StandoutNobel
Dephosphorylation and activation of Xenopusp34cdc2 protein kinase during the cell cycle
1989 StandoutNatureNobel
Histone acetylation and transcriptional regulatory mechanisms
1998 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Acetyl-coenzyme A synthetase (AMP forming)
2004
Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+
1988 StandoutNatureNobel
Role of histone tails in nucleosome remodeling by Drosophila NURF
1997
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function invivo
1997
RSC, an Essential, Abundant Chromatin-Remodeling Complex
1996 StandoutNobel
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation
1996
The acetyltransferase activity of CBP stimulates transcription
1998
Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication
1990 StandoutNobel
The language of covalent histone modifications
2000 StandoutNature
Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase
1998
Sin3: a flexible regulator of global gene expression and genome stability
2004
Virus Infection Leads to Localized Hyperacetylation of Histones H3 and H4 at the IFN-β Promoter
1999
The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product
1990 StandoutNobel
When Checkpoints Fail
1997 StandoutNobel
Involvement of p34cdc2 in establishing the dependency of S phase on mitosis
1991 StandoutNatureNobel
Natural Cyclopeptaibiotics and Related Cyclic Tetrapeptides: Structural Diversity and Future Prospects
2008
Size control of cell division
1987
The TAFII250 Subunit of TFIID Has Histone Acetyltransferase Activity
1996
Regulation of p34cdc2 protein kinase during mitosis
1989 StandoutNobel
Histone deacetylation in epigenetics: An attractive target for anticancer therapy
2005
Telomeres Do D-Loop–T-Loop
1999 StandoutNobel
Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein
1988 StandoutNatureNobel
Histone deacetylases and cancer: causes and therapies
2001 Standout
Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase
1990 StandoutNatureNobel
The C. elegans genome sequencing project: a beginning
1992 StandoutNatureNobel
Translation of cyclin mRNA is necessary for extracts of activated Xenopus eggs to enter mitosis
1989 StandoutNobel
Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+
1988 StandoutNobel
Deoxyribonucleoside triphosphate levels: A critical factor in the maintenance of genetic stability
1994
Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.
1997
The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos
1992 StandoutNobel
twine, a cdc25 homolog that functions in the male and female germline of drosophila
1992 StandoutNobel
Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes
1999
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
Regulation of mitosis by cyclic accumulation of p80cdc25 mitotic inducer in fission yeast
1990 StandoutNatureNobel
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis
1989 StandoutNatureNobel
Dynamics of histone acetylation in vivo. A function for acetylation turnover?
2002
Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation
1996
Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins
1999
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex
1994 StandoutNobel
Stimulation of c‐MYC transcriptional activity and acetylation by recruitment of the cofactor CBP
2003
cdc25+ functions as an inducer in the mitotic control of fission yeast
1986 StandoutNobel
Nuclear ADP-Ribosylation Reactions in Mammalian Cells: Where Are We Today and Where Are We Going?
2006
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis
1987 StandoutNobel
The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation
1986 StandoutNobel
Molecular Approaches to Discover Marine Natural Product Anticancer Leads – An Update from a Drug Discovery Group Collaboration
2003
How to Improve the Success Rate of Mouse Cloning Technology
2010
HAT1 and HAT2 Proteins Are Components of a Yeast Nuclear Histone Acetyltransferase Enzyme Specific for Free Histone H4
1998
Class I Histone Deacetylase-Selective Novel Synthetic Inhibitors Potently Inhibit Human Tumor Proliferation
2004
Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog
1987 StandoutNobel
Complementation of the Mitotic Activator, p80 cdc25 , by a Human Protein-tyrosine Phosphatase
1990 StandoutScienceNobel
Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
2021 StandoutNobel
Control of cell-cycle timing in early embryos of Caenorhabditis elegans
1985
Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase
1997 StandoutNobel
Subtype Selective Substrates for Histone Deacetylases
2004
Altered cell-division rates after laser-induced cell fusion in nematode embryos
1984
The role of cyclin B in meiosis I.
1989
Histone Deacetylase Inhibitors: From Bench to Clinic
2008
ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION
1998
Histone Deacetylase Inhibitors
2003
Translating the Histone Code
2001 StandoutScience
Cell Cycle Regulation in Yeast
1986 StandoutNobel
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Sequence analysis of mouse vomeronasal receptor gene clusters reveals common promoter motifs and a history of recent expansion
2001 StandoutNobel
Purification of MPF from starfish: Identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation
1989 StandoutNobel
Syntheses of Thailandepsin B Pseudo‐Natural Products: Access to New Highly Potent HDAC Inhibitors via Late‐Stage Modification
2020
Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro.
1996
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
Disruption of Higher-Order Folding by Core Histone Acetylation Dramatically Enhances Transcription of Nucleosomal Arrays by RNA Polymerase III
1998
NMR structure of the calreticulin P-domain
2001 StandoutNobel
The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation.
1996
Efficient Transcriptional Silencing in Saccharomyces cerevisiae Requires a Heterochromatin Histone Acetylation Pattern
1996
CLINICAL DEVELOPMENT OF HISTONE DEACETYLASE INHIBITORS AS ANTICANCER AGENTS
2004
Works of Peter Loidl being referenced
Purification and characterization of the cytoplasmic histone acetyltransferase B of maize embryos
1996
Histone deacetylases in replicative senescence: evidence for a senescence‐specific form of HDAC‐2
2001
Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity
1997
Histone acetylation: facts and questions
1994
A comparative study of histone deacetylases of plant, fungal and vertebrate cells
1996
Enzymes involved in the dynamic equilibrium of core histone acetylation of Physarum polycephalum
1992
Substrate and sequential site specificity of cytoplasmic histone acetyltransferases of maize and rat liver
1998
A non-isotopic assay for histone deacetylase activity
1999
Histone deacetylase
1993
Histone acetylation: plants and fungi as model systems for the investigation of histone deacetylases
2001
Subcellular Location of Enzymes Involved in Core Histone Acetylation
1994
Specificity of Zea mays histone deacetylase is regulated by phosphorylation.
1992
Histone acetylation in Zea mays.I. Activities of histone acetyltransferases and histone deacetylases.
1991
Histone acetylation in Zea mays. II. Biological significance of post-translational histone acetylation during embryo germination.
1991
Amide Analogues of Trichostatin A as Inhibitors of Histone Deacetylase and Inducers of Terminal Cell Differentiation
1999
Binding Mode Analysis of 3-(4-Benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: A New Synthetic Histone Deacetylase Inhibitor Inducing Histone Hyperacetylation, Growth Inhibition, and Terminal Cell Differentiation
2002
Discovery of (Aryloxopropenyl)pyrrolyl Hydroxyamides as Selective Inhibitors of Class IIa Histone Deacetylase Homologue HD1-A
2003
Different Types of Maize Histone Deacetylases Are Distinguished by a Highly Complex Substrate and Site Specificity
1999
Analogues of trichosтatin a and trapoxin B as histone deacetylase inhibitors
1997
Acceleration of mitosis induced by mitotic stimulators of Physarum polycephalum
1982
Action of 5′‐fluorodeoxyuridine on synchronous nuclear division and thymidylate synthetase activity of Physarum polycephalum
1982
Cell cycle-dependent ADP-ribosylation of the nuclear matrix.
1991
Inhibition of maize histone deacetylases by HC toxin, the host-selective toxin of Cochliobolus carbonum.
1995
Identification of Maize Histone Deacetylase HD2 as an Acidic Nucleolar Phosphoprotein
1997 Science
Cell-cycle-dependent effects of sodium-n-butyrate in Physarum polycephalum
1982
Biochemical Methods for Analysis of Histone Deacetylases
1998
Control of mitotic synchrony in Physarum polycephalum. Phase shifting by fusion of heterophasic plasmodia contradicts a limit cycle oscillator model.
1982
Purification and Characterization of a High Molecular Weight Histone Deacetylase Complex (HD2) of Maize Embryos
1996
3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 2. Effect of Pyrrole-C2 and/or -C4 Substitutions on Biological Activity
2004
Structure−Activity Relationships on Phenylalanine-Containing Inhibitors of Histone Deacetylase: In Vitro Enzyme Inhibition, Induction of Differentiation, and Inhibition of Proliferation in Friend Leukemic Cells
2002
RPD3-Type Histone Deacetylases in Maize Embryos,
2000
3-(4-Aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a New Class of Synthetic Histone Deacetylase Inhibitors
2001
Histone acetylation: facts and questions
1994
3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 3. Discovery of Novel Lead Compounds through Structure-Based Drug Design and Docking Studies,
2004
First non-radioactive assay for in vitro screening of histone deacetylase inhibitors.
2000
3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 1. Design, Synthesis, Biological Evaluation, and Binding Mode Studies Performed through Three Different Docking Procedures
2003