Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals
2012 Science
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
2016 Science
Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis
2015
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Balance of MafB and PU.1 specifies alternative macrophage or dendritic cell fate
2004
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Chromatin state dynamics during blood formation
2014 Science
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
2017
ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline
2016
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3
2012
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution
2016
A Robust and Highly Efficient Immune Cell Reprogramming System
2009
deepTools2: a next generation web server for deep-sequencing data analysis
2016 Standout
m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells
2014 Standout
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Function of a Foxp3 cis -Element in Protecting Regulatory T Cell Identity
2014
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
2015 Standout
High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states
2013
Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities
2014
Differential L1 regulation in pluripotent stem cells of humans and apes
2013 Nature
Transcription factors in myeloid development: balancing differentiation with transformation
2007
Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges
2013
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance
2021
A universal RNAi-based logic evaluator that operates in mammalian cells
2007
Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding
2018
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
Direct lineage conversions: unnatural but useful?
2011
Stepwise Reprogramming of B Cells into Macrophages
2004
Molecular basis of ancestral vertebrate electroreception
2017 StandoutNatureNobel
Forcing cells to change lineages
2009 Nature
Global mapping of miRNA-target interactions in cattle (Bos taurus)
2017 StandoutNobel
Short-term memory of danger signals and environmental stimuli in immune cells
2013
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Transcriptional Control of Inflammatory Responses
2014
Modern human changes in regulatory regions implicated in cortical development
2020
HiC-Pro: an optimized and flexible pipeline for Hi-C data processing
2015
The Molecular Architecture of Ribbon Presynaptic Terminals
2009
miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity
2015 StandoutNobel
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Foxp3 Exploits a Pre-Existent Enhancer Landscape for Regulatory T Cell Lineage Specification
2012
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Remodeling of the Enhancer Landscape during Macrophage Activation Is Coupled to Enhancer Transcription
2013
Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions
2011
A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function
2020
MiR-150 Controls B Cell Differentiation by Targeting the Transcription Factor c-Myb
2007
Pioneer transcription factors: establishing competence for gene expression
2011
chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data
2017
Dissecting noncoding and pathogen RNA–protein interactomes
2014
Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors
2018
The Transcriptional Repressor GFI-1 Antagonizes PU.1 Activity through Protein-Protein Interaction
2007
Argonaute CLIP Defines a Deregulated miR-122-Bound Transcriptome that Correlates with Patient Survival in Human Liver Cancer
2017 StandoutNobel
Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development
2013
PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors
2018
Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells
2021 StandoutNobel
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes
2016
Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
2014
Transcription factors: from enhancer binding to developmental control
2012 Standout
Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
2024 StandoutNobel
Myeloid Lineage Commitment from the Hematopoietic Stem Cell
2007
ChIPmentation: fast, robust, low-input ChIP-seq for histones and transcription factors
2015
Bv8 regulates myeloid-cell-dependent tumour angiogenesis
2007 Nature
Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8+ T Cell Exhaustion versus Memory
2012
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Latent Enhancers Activated by Stimulation in Differentiated Cells
2013
Cancer-related inflammation
2008 StandoutNature
Reprogramming of Committed T Cell Progenitors to Macrophages and Dendritic Cells by C/EBPα and PU.1 Transcription Factors
2006
The Kruppel‐like factor KLF4 is a critical regulator of monocyte differentiation
2007
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
2014 Standout
Comprehensive Integration of Single-Cell Data
2019 Standout
Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation
2018
Neutrophil recruitment and function in health and inflammation
2013 Standout
Negotiation of the T Lineage Fate Decision by Transcription-Factor Interplay and Microenvironmental Signals
2007
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription
2017
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Coregulation of Transcription Factor Binding and Nucleosome Occupancy through DNA Features of Mammalian Enhancers
2014
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
The role of chromatin dynamics in immune cell development
2014
Development of Monocytes, Macrophages, and Dendritic Cells
2010 StandoutScience
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B–cell differentiation
2013
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
Regulatory T Cells: Mechanisms of Differentiation and Function
2007 Standout
Disentangling the Many Layers of Eukaryotic Transcriptional Regulation
2012
Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells
2009
PU.1 and C/EBPα/β convert fibroblasts into macrophage-like cells
2008
Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells
2013
GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment
2019
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Spatiotemporal transcriptomic divergence across human and macaque brain development
2018 Science
Targeting Piezo1 unleashes innate immunity against cancer and infectious disease
2020
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Histone H3K27ac separates active from poised enhancers and predicts developmental state
2010 Standout
Nascent-Seq analysis of Drosophila cycling gene expression
2013 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Macrophages: Gatekeepers of Tissue Integrity
2013
Chromatin Contributions to the Regulation of Innate Immunity
2014
Works of Peter Laslo being referenced
TRPC‐like conductance mediates restoration of intracellular Ca 2+ in cochlear outer hair cells in the guinea pig and rat
2006
Multilineage Transcriptional Priming and Determination of Alternate Hematopoietic Cell Fates
2006
A Recurrent Network Involving the Transcription Factors PU.1 and Gfi1 Orchestrates Innate and Adaptive Immune Cell Fates
2009
Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system
2008
Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPα ratio and granulocyte colony-stimulating factor
2003
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
2010 Standout
A Two-Step, PU.1-Dependent Mechanism for Developmentally Regulated Chromatin Remodeling and Transcription of the c-fms Gene
2006