Citation Impact
Citing Papers
Observation of Covalent Intermediates in an Enzyme Mechanism at Atomic Resolution
2001 Science
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
The role of liquid–liquid phase separation in aggregation of the TDP-43 low-complexity domain
2019 Standout
Evolution of a designed retro-aldolase leads to complete active site remodeling
2013 StandoutNobel
PRODRG: a tool for high-throughput crystallography of protein–ligand complexes
2004 Standout
The Structures of Four Macrolide Antibiotics Bound to the Large Ribosomal Subunit
2002 StandoutNobel
Structural Analyses of Covalent Enzyme–Substrate Analog Complexes Reveal Strengths and Limitations of De Novo Enzyme Design
2011 StandoutNobel
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
2007 Standout
Exploration of Alternate Catalytic Mechanisms and Optimization Strategies for Retroaldolase Design
2013 StandoutNobel
The aggregation kinetics of Alzheimer's β‐amyloid peptide is controlled by stochastic nucleation
2005
Computational Enzyme Design
2013 StandoutNobel
Atomic structures of amyloid cross-β spines reveal varied steric zippers
2007 StandoutNature
An exciting but challenging road ahead for computational enzyme design
2010 StandoutNobel
Analysis of the Class I Aldolase Binding Site Architecture Based on the Crystal Structure of 2-Deoxyribose-5-phosphate Aldolase at 0.99 Å Resolution
2004
NMR studies in aqueous solution fail to identify significant conformational differences between the monomeric forms of two Alzheimer peptides with widely different plaque‐competence, Aβ(1–40)ox and Aβ(1–42)ox
2001 StandoutNobel
Protein aggregation and neurodegenerative disease
2004 Standout
Structural and kinetic features of amyloid β-protein fibrillogenesis
1998
Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase
2016 StandoutNobel
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
Neurotoxic protein oligomers — what you see is not always what you get
2005
The Toxicity of the Alzheimer's β-Amyloid Peptide Correlates with a Distinct Fiber Morphology
1997
Regulated Membrane Recruitment of Dynamin-2 Mediated by Sorting Nexin 9
2004
The Amyloid State of Proteins in Human Diseases
2012 Standout
Adenine dinucleotides: a novel class of signalling molecules
1996
From the genome sequence to the proteome and back: Evaluation of E. coli genome annotation with a 2‐D gel‐based proteomics approach
2007
Mutations that Reduce Aggregation of the Alzheimer's Aβ42 Peptide: an Unbiased Search for the Sequence Determinants of Aβ Amyloidogenesis
2002
Alzheimer Aβ neurotoxicity: Promotion by antichymotrypsin, ApoE4; inhibition by Aβ-related peptides
1996
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
2012 Standout
The amyloid state and its association with protein misfolding diseases
2014 Standout
Protein Misfolding, Functional Amyloid, and Human Disease
2006 Standout
Receptors for Purines and Pyrimidines
1998 Standout
A Century of Alzheimer's Disease
2006 StandoutScience
3D structure of Alzheimer's amyloid-β(1–42) fibrils
2005 Standout
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
Selective Enrichment of Azide-Containing Peptides from Complex Mixtures
2009 StandoutNobel
Receptors for Purines and Pyrimidines
2012 Standout
De Novo Computational Design of Retro-Aldol Enzymes
2008 StandoutScienceNobel
Proline-catalyzed asymmetric reactions
2002 StandoutNobel
Self-Assembly of β-Amyloid 42 Is Retarded by Small Molecular Ligands at the Stage of Structural Intermediates
2000 StandoutNobel
Mechanisms of Endocytosis
2009 Standout
Computerbasiertes Enzymdesign
2013 StandoutNobel
Works of Peter Jakob being referenced
Depletion of the high-abundance plasma proteins
2004
A Biotechnological Method Provides Access to Aggregation Competent Monomeric Alzheimer's 1–42 Residue Amyloid Peptide
1995
Diadenosine 5′,5‴-P,P-triphosphate in eukaryotic cells: Identification and quantitation
1983
Crystal Structure of Fructose-1,6-bisphosphate Aldolase from the Human Malaria Parasite Plasmodium falciparum,
1998