Standout Papers
Citation Impact
Citing Papers
Organization of the Influenza Virus Replication Machinery
2012 Science
The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04
2006
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity
2007
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Elucidating Design Principles for Engineering Cell‐Derived Vesicles to Inhibit SARS‐CoV‐2 Infection
2022
gp340 Expressed on Human Genital Epithelia Binds HIV-1 Envelope Protein and Facilitates Viral Transmission
2007 StandoutNobel
Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells
2005
Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic
2009 StandoutNature
Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification
2019 StandoutNobel
An Inhibitory Activity in Human Cells Restricts the Function of an Avian-like Influenza Virus Polymerase
2008 StandoutNobel
Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?
2002
Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
2024 StandoutNobel
Virulence determinants of pandemic influenza viruses
2011
Single mutation at the amino acid position 627 of PB2 that leads to increased virulence of an H5N1 avian influenza virus during adaptation in mice can be compensated by multiple mutations at other sites of PB2
2009
H5N1 virus outbreak in migratory waterfowl
2005 Nature
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
2010 Standout
Charting the Host Adaptation of Influenza Viruses
2010
Characterization of the 1918 influenza virus polymerase genes
2005 Nature
Genetic Compatibility and Virulence of Reassortants Derived from Contemporary Avian H5N1 and Human H3N2 Influenza A Viruses
2008
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia
2006 Standout
Host-range determinants on the PB2 protein of influenza A viruses control the interaction between the viral polymerase and nucleoprotein in human cells
2007
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Vaccine Efficacy in Senescent Mice Challenged with Recombinant SARS-CoV Bearing Epidemic and Zoonotic Spike Variants
2006
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
Identifying Changes in Selective Constraints: Host Shifts in Influenza
2009
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Pattern Recognition Receptors and Inflammation
2010 Standout
A new vision of immunity: homeostasis of the superorganism
2010
The Human/Animal Interface: Emergence and Resurgence of Zoonotic Infectious Diseases
2007
Transcriptomic profiling facilitates classification of response to influenza challenge
2014
Nonresolving Inflammation
2010 Standout
The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus
2014 StandoutNobel
Coronavirus as a possible cause of severe acute respiratory syndrome
2003 Standout
Sex and gender: modifiers of health, disease, and medicine
2020 Standout
The scaling laws of human travel
2006 StandoutNature
Lethal H5N1 influenza viruses escape host anti-viral cytokine responses
2002
Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
2011 StandoutNature
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Syrian hamsters as a model of lung injury with SARS-CoV-2 infection: Pathologic, physiologic, and detailed molecular profiling
2021
Sialic acid-specific lectins: occurrence, specificity and function
2006
Foundations for engineering biology
2005 StandoutNature
PB2 amino acid at position 627 affects replicative efficiency, but not cell tropism, of Hong Kong H5N1 influenza A viruses in mice
2004
Respiratory innate immune proteins differentially modulate the neutrophil respiratory burst response to influenza A virus
2005
Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit
2008
Virus and host interactions critical for filoviral RNA synthesis as therapeutic targets
2018
Virulence May Determine the Necessary Duration and Dosage of Oseltamivir Treatment for Highly Pathogenic A/Vietnam/1203/04 Influenza Virus in Mice
2005
The challenge of emerging and re-emerging infectious diseases
2004 StandoutNature
Influenza Virus Evolution, Host Adaptation, and Pandemic Formation
2010
Chemical Approaches To Perturb, Profile, and Perceive Glycans
2009 StandoutNobel
Strategies for mitigating an influenza pandemic
2006 StandoutNature
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
The Molecular Basis of the Pathogenicity of the Dutch Highly Pathogenic Human Influenza A H7N7 Viruses
2007
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
2020 StandoutNature
Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model
2019
Positive Selection Drives Evolution at the Host–Filovirus Interaction Surface
2016
Overview of therapeutic drug research for COVID-19 in China
2020
Emergence and pandemic potential of swine-origin H1N1 influenza virus
2009 Nature
Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N
2009
Influenza
2018 Nobel
The next influenza pandemic: lessons from Hong Kong
2003
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus
2006 Nature
Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies
2018 StandoutNobel
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
2008 StandoutNature
Interaction of Polymerase Subunit PB2 and NP with Importin α1 Is a Determinant of Host Range of Influenza A Virus
2008
The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1
2009 Nobel
SARS-CoV-2 vaccines in development
2020 StandoutNature
Glycan Microarray Analysis of the Hemagglutinins from Modern and Pandemic Influenza Viruses Reveals Different Receptor Specificities
2005
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
2020 Standout
Reassortment and Mutation of the Avian Influenza Virus Polymerase PA Subunit Overcome Species Barriers
2011 StandoutNobel
Characterization of the Reconstructed 1918 Spanish Influenza Pandemic Virus
2005 Science
A Two-Amino Acid Change in the Hemagglutinin of the 1918 Influenza Virus Abolishes Transmission
2007 Science
Crystal Structure of the Marburg Virus VP35 Oligomerization Domain
2016
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Live Attenuated Influenza Viruses Containing NS1 Truncations as Vaccine Candidates against H5N1 Highly Pathogenic Avian Influenza
2008
Lethal Dissemination of H5N1 Influenza Virus Is Associated with Dysregulation of Inflammation and Lipoxin Signaling in a Mouse Model of Infection
2010
1918 Influenza: the Mother of All Pandemics
2006 Standout
Identification of Cellular Interaction Partners of the Influenza Virus Ribonucleoprotein Complex and Polymerase Complex Using Proteomic-Based Approaches
2006
Sialobiology of Influenza: Molecular Mechanism of Host Range Variation of Influenza Viruses
2005
A Single-Amino-Acid Substitution in a Polymerase Protein of an H5N1 Influenza Virus Is Associated with Systemic Infection and Impaired T-Cell Activation in Mice
2009
Patterns of nucleotide misincorporations during enzymatic amplification and direct large-scale sequencing of ancient DNA
2006 StandoutNobel
Advances in the development of influenza virus vaccines
2015
Evidence for Avian and Human Host Cell Factors That Affect the Activity of Influenza Virus Polymerase
2010
Fc receptors in antibody‐dependent enhancement of viral infections
2015
Global Host Immune Response: Pathogenesis and Transcriptional Profiling of Type A Influenza Viruses Expressing the Hemagglutinin and Neuraminidase Genes from the 1918 Pandemic Virus
2004
Molecular Determinants of Adaptation of Highly Pathogenic Avian Influenza H7N7 Viruses to Efficient Replication in the Human Host
2009
Properties and Dissemination of H5N1 Viruses Isolated during an Influenza Outbreak in Migratory Waterfowl in Western China
2006
Virology. A molecular whodunit.
2001
Global Patterns of Influenza A Virus in Wild Birds
2006 StandoutScience
Innate Defense against Influenza A Virus: Activity of Human Neutrophil Defensins and Interactions of Defensins with Surfactant Protein D
2006
1918 Influenza: the Mother of All Pandemics
2006 Standout
Cytokine Storm
2020 Standout
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
PA Residues in the 2009 H1N1 Pandemic Influenza Virus Enhance Avian Influenza Virus Polymerase Activity in Mammalian Cells
2011
Disease Tolerance as a Defense Strategy
2012 StandoutScience
Emergence of multiple genotypes of H5N1 avian influenza viruses in Hong Kong SAR
2002
Adaptive strategies of the influenza virus polymerase for replication in humans
2009 StandoutNobel
Cross-Species Virus Transmission and the Emergence of New Epidemic Diseases
2008
The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host
2005
Highly Pathogenic H5N1 Influenza Virus Infection in Migratory Birds
2005 Science
A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity
2008
Growth of H5N1 Influenza A Viruses in the Upper Respiratory Tracts of Mice
2007
A Single Amino Acid Substitution in 1918 Influenza Virus Hemagglutinin Changes Receptor Binding Specificity
2005
High Level of Genetic Compatibility between Swine-Origin H1N1 and Highly Pathogenic Avian H5N1 Influenza Viruses
2010
Host Restriction of Avian Influenza Viruses at the Level of the Ribonucleoproteins
2008
Compatibility among Polymerase Subunit Proteins Is a Restricting Factor in Reassortment between Equine H7N7 and Human H3N2 Influenza Viruses
2008
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Are We Ready for Pandemic Influenza?
2003 Science
Meat consumption, health, and the environment
2018 StandoutScience
Imaging the glycome
2008 StandoutNobel
Glycopolymer Nanobiotechnology
2015
The ecology of the microbiome: Networks, competition, and stability
2015 StandoutScience
Adaptive Mutations Resulting in Enhanced Polymerase Activity Contribute to High Virulence of Influenza A Virus in Mice
2009
Reemerging H5N1 Influenza Viruses in Hong Kong in 2002 Are Highly Pathogenic to Ducks
2004
Form Follows Function: Nanoparticle Shape and Its Implications for Nanomedicine
2017
PB2 Residue 158 Is a Pathogenic Determinant of Pandemic H1N1 and H5 Influenza A Viruses in Mice
2010
Avian Influenza A (H5N1) Infection in Humans
2005
Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air
2009
PB2 Protein of a Highly Pathogenic Avian Influenza Virus Strain A/chicken/Yamaguchi/7/2004 (H5N1) Determines Its Replication Potential in Pigs
2008
Microbiota regulates immune defense against respiratory tract influenza A virus infection
2011 Standout
Lethality to Ferrets of H5N1 Influenza Viruses Isolated from Humans and Poultry in 2004
2005
Virulence and Genetic Compatibility of Polymerase Reassortant Viruses Derived from the Pandemic (H1N1) 2009 Influenza Virus and Circulating Influenza A Viruses
2011
Photothermal Nanomaterials: A Powerful Light-to-Heat Converter
2023 Standout
Role of Ran Binding Protein 5 in Nuclear Import and Assembly of the Influenza Virus RNA Polymerase Complex
2006
Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome
2004
N‐Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen‐Presenting Cells through Dectin‐1 and Dectin‐2
2018 StandoutNobel
Host Range Restriction and Pathogenicity in the Context of Influenza Pandemic
2006
THE ORIGINS OF NEW PANDEMIC VIRUSES: The Acquisition of New Host Ranges by Canine Parvovirus and Influenza A Viruses
2005
Works of Peter Halfmann being referenced
The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses
2016
The spatio-temporal distribution dynamics of Ebola virus proteins and RNA in infected cells
2013
Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism
2012
Human Influenza A Viral Genes Responsible for the Restriction of Its Replication in Duck Intestine
2002
An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies
2022
Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus
2007 Nature
Ebolavirus Is Internalized into Host Cells via Macropinocytosis in a Viral Glycoprotein-Dependent Manner
2010
Transmission of SARS-CoV-2 in domestic cats imposes a narrow bottleneck
2021
Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus
2004 Nature
An Ebola whole-virus vaccine is protective in nonhuman primates
2015 Science
Characterization of a Human H5N1 Influenza A Virus Isolated in 2003
2005
DNA Topoisomerase 1 Facilitates the Transcription and Replication of the Ebola Virus Genome
2013
Molecular Basis for High Virulence of Hong Kong H5N1 Influenza A Viruses
2001 Science
Structure of an Antibody in Complex with Its Mucin Domain Linear Epitope That Is Protective against Ebola Virus
2011