Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
2013 StandoutScience
Recognition of a Ubiquitous Self Antigen by Prostate Cancer-Infiltrating CD8 + T Lymphocytes
2008 StandoutScienceNobel
Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation
2002 StandoutNobel
Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression
1997 Nature
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth
1998 Nature
The WRPW Motif of the Hairy-Related Basic Helix-Loop-Helix Repressor Proteins Acts as a 4-Amino-Acid Transcription Repression and Protein-Protein Interaction Domain
1996
FoxOs Enforce a Progression Checkpoint to Constrain mTORC1-Activated Renal Tumorigenesis
2010 StandoutNobel
Induction of Mxi1-SRα by FOXO3a Contributes to Repression of Myc-Dependent Gene Expression
2007
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival
2005
Structure of the Histone Acetyltransferase Hat1
1998 StandoutNobel
A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression
1997 Nature
Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A
1997
The human papillomavirus E7 protein as a transforming and transactivating factor
1993
Papillomaviruses Causing Cancer: Evasion From Host-Cell Control in Early Events in Carcinogenesis
2000 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Differential Effects of Nuclear Receptor Corepressor (N-CoR) Expression Levels on Retinoic Acid Receptor-Mediated Repression Support the Existence of Dynamically Regulated Corepressor Complexes
1997
Papillomavirus infections — a major cause of human cancers
1996 StandoutNobel
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F
1992
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
The Novel ATM-Related Protein TRRAP Is an Essential Cofactor for the c-Myc and E2F Oncoproteins
1998
The price of repression
1995
TCR Antigen–Induced Cell Death Occurs from a Late G1 Phase Cell Cycle Check Point
1998
The language of covalent histone modifications
2000 StandoutNature
Sin3: a flexible regulator of global gene expression and genome stability
2004
Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins.
1994
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
Repression by Ume6 Involves Recruitment of a Complex Containing Sin3 Corepressor and Rpd3 Histone Deacetylase to Target Promoters
1997
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
SAP30, a Component of the mSin3 Corepressor Complex Involved in N-CoR-Mediated Repression by Specific Transcription Factors
1998
Transcriptional Repression by RING Finger Protein TIF1 That Interacts with the KRAB Repressor Domain of KOX1
1996
Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change
1995 StandoutNobel
The Essential Cofactor TRRAP Recruits the Histone Acetyltransferase hGCN5 to c-Myc
2000
A transcriptional co-repressor that interacts with nuclear hormone receptors
1995 StandoutNature
E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
2002
A Role for Mammalian Sin3 in Permanent Gene Silencing
2008 StandoutNobel
Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor
1995 StandoutNature
Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation
1999
Expression ofmyc-family,myc-interacting, andmyc-target genes during preimplantation mouse development
1997
A pancreatic islet-specific microRNA regulates insulin secretion
2004 StandoutNature
HIF and c-Myc: Sibling Rivals for Control of Cancer Cell Metabolism and Proliferation
2007
E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation
1996 StandoutNobel
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex
1997
Silencing of microRNAs in vivo with ‘antagomirs’
2005 StandoutNature
Histone acetylation in chromatin structure and transcription
1997 StandoutNature
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes
1999
Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression
1997
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53
1998
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase
1997
Cellular transformation by papilomavirus oncorproteins
1993
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development.
1995
Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development.
1994
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
Differential Specificity for Binding of Retinoblastoma Binding Protein 2 to RB, pl07, and TATA-Binding Protein
1994
Association of the human papillomavirus type 16 E7 protein with the S-phase-specific E2F-cyclin A complex.
1993
Functional importance of complex formation between the retinoblastoma tumor suppressor family and adenovirus E1A proteins as determined by mutational analysis of E1A conserved region 2
1994
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
Unique forms of human and mouse nuclear receptor corepressor SMRT
1999
Association of the Human Papillomavirus Type 16 E7 Protein with the S-Phase-Specific E2F-Cyclin A Complex
1993
Long-term genome stability and minimal genotypic and phenotypic alterations in HPV16 E7-, but not E6-, immortalized human uroepithelial cells.
1994
A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites.
1995 StandoutNobel
The coregulator exchange in transcriptional functions of nuclear receptors
2000 Standout
Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7.
1994
Cancer Cell Cycles
1996 StandoutScience
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product.
1993 StandoutNobel
p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein.
1994
SEROTONIN IMMUNOREACTIVITY IN CARCINOID TUMOURS DEMONSTRATED BY A MONOCLONAL ANTIBODY
1982 StandoutNobel
Reversible repression of papillomavirus oncogene expression in cervical carcinoma cells: consequences for the phenotype and E6-p53 and E7-pRB interactions
1994
Simian virus 40 large T antigen associates with cyclin A and p33cdk2
1993 StandoutNobel
The human papillomavirus E7 oncoprotein and the cellular transcription factor E2F bind to separate sites on the retinoblastoma tumor suppressor protein
1993
Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53.
1994
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
A Novel Rb- and p300-Binding Protein Inhibits Transactivation by MyoD
2000
Characterization of a human RPD3 ortholog, HDAC3
1998
Loss of HCF-1–Chromatin Association Precedes Temperature-Induced Growth Arrest of tsBN67 Cells
2001
ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION
1998
The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E.
1993
Sequential activation of cyclin E and cyclin A gene expression by human papillomavirus type 16 E7 through sequences necessary for transformation
1995
Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.
1995
Identification of Mammalian Sds3 as an Integral Component of the Sin3/Histone Deacetylase Corepressor Complex
2002
Sequence analysis of mouse vomeronasal receptor gene clusters reveals common promoter motifs and a history of recent expansion
2001 StandoutNobel
The human papillomavirus type 16 E7 protein complements adenovirus type 5 E1A amino-terminus-dependent transactivation of adenovirus type 5 early genes and increases ATF and Oct-1 DNA binding activity
1996
Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A
1998
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Notch Signaling: Cell Fate Control and Signal Integration in Development
1999 StandoutScience
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.
1994 Standout
Carcinoid-islet cell tumors of the duodenum
1971
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factors.
1996
Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes.
1993
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3
1996
Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein.
1994
Shared role of the pRB-related p130 and p107 proteins in limb development.
1996
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.
1993
RBP1 Recruits Both Histone Deacetylase-Dependent and -Independent Repression Activities to Retinoblastoma Family Proteins
1999 StandoutNobel
RB and hbrm cooperate to repress the activation functions of E2F1
1997
Identification of distinct roles for separate E1A domains in disruption of E2F complexes.
1993
Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes
1998
Comparison of the properties of the E6 and E7 genes of low- and high-risk cutaneous papillomaviruses reveals strongly transforming and high Rb-binding activity for the E7 protein of the low-risk human papillomavirus type 1
1994
Works of Peter Guida being referenced
Mouse Sin3A interacts with and can functionally substitute for the amino-terminal repression of the Myc antagonist Mxi1.
1996
An amino-terminal domain of Mxi1 mediates anti-myc oncogenic activity and interacts with a homolog of the Yeast Transcriptional Repressor SIN3
1995
Zollinger-ellison syndrome with interesting variations
1966
Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins
1992
Adenovirus E1A makes two distinct contacts with the retinoblastoma protein
1992