Citation Impact
Citing Papers
Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei
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2009
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CARNITINE PALMITOYL TRANSFERASE‐I INHIBITION IS NOT ASSOCIATED WITH CARDIAC HYPERTROPHY IN RATS FED A HIGH‐FAT DIET
2006
Oxidative stress in prostate cancer
2009
Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist
1999 Standout
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2011
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2003
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1999
A realistic clinical perspective of tamoxifen and endometrial carcinogenesis
1996
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2005
Gene Regulatory Mechanisms Governing Energy Metabolism during Cardiac Hypertrophic Growth
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The Failing Heart — An Engine Out of Fuel
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1990 Standout
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Iron Regulatory Proteins Secure Mitochondrial Iron Sufficiency and Function
2010
Marine pharmacology in 2003–2004: Anti-tumour and cytotoxic compounds
2006
Porphyrias
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Soft-Tissue Sarcomas in Adults
2005 Standout
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2009
Structurally Mapping Endogenous Heme in the CcmCDE Membrane Complex for Cytochrome c Biogenesis
2018 StandoutNobel
Omega-3 Polyunsaturated Fatty Acids and Cardiovascular Diseases
2009 Standout
Long-term tamoxifen citrate use and potential ocular toxicity
1998
Effects of Raloxifene on Bone Mineral Density, Serum Cholesterol Concentrations, and Uterine Endometrium in Postmenopausal Women
1997 Standout
Physicochemical drug properties associated within vivotoxicological outcomes: a review
2009
How to improve R&D productivity: the pharmaceutical industry's grand challenge
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1998
Two to Tango: Regulation of Mammalian Iron Metabolism
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Novel Roles for MLH3 Deficiency and TLE6-Like Amplification in DNA Mismatch Repair-Deficient Gastrointestinal Tumorigenesis and Progression
2008 StandoutNobel
The application of discovery toxicology and pathology towards the design of safer pharmaceutical lead candidates
2007
Myocardial Substrate Metabolism in the Normal and Failing Heart
2005 Standout
Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
1998 Standout
HRG1 Is Essential for Heme Transport from the Phagolysosome of Macrophages during Erythrophagocytosis
2013
Toremifene: An evaluation of its safety profile
2005
Plant Polyphenols as Dietary Antioxidants in Human Health and Disease
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Trabectedin in pre-treated patients with advanced or metastatic soft tissue sarcoma: a phase II study evaluating co-treatment with dexamethasone
2010
Metabolomics: beyond biomarkers and towards mechanisms
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PPARγ signaling and metabolism: the good, the bad and the future
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Selective estrogen receptor modulators (SERMs): Mechanisms of anticarcinogenesis and drug resistance
2005
Comparing the function of the corticospinal system in different species: Organizational differences for motor specialization?
2005
The antioxidant and pro-oxidant activities of green tea polyphenols: A role in cancer prevention
2010 Standout
Flavonoids: an overview
2016 Standout
Toxicology for the twenty-first century
2009 StandoutNature
Hepatic peroxisome proliferation in rodents and its significance for humans
1993
The Use of Partial Fatty Acid Oxidation Inhibitors for Metabolic Therapy of Angina Pectoris and Heart Failure
2002
Chemoprevention of Mammary Carcinogenesis in the Rat: Combined Use of Raloxifene and 9-cis-Retinoic Acid
1996
The malonyl CoA axis as a potential target for treating ischaemic heart disease
2008
Oxidative Stress: Harms and Benefits for Human Health
2017 Standout
Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial
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Removal of cytostatic drugs from aquatic environment: A review
2013 Standout
ET-743: A Novel Agent with Activity in Soft Tissue Sarcomas
2005
Estrogen Receptors as Therapeutic Targets in Breast Cancer
2008
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
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Evaluation of Possible Carcinogenic Risk to Humans Based on Liver Tumors in Rodent Assays
2010
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
2015 Standout
Copper Active Sites in Biology
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Liver disease in erythropoietic protoporphyria: insights and implications for management
2007
Chemicals from lignin: an interplay of lignocellulose fractionation, depolymerisation, and upgrading
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Fatty Acid Utilization in the Hypertrophied and Failing Heart: Molecular Regulatory Mechanisms
1999
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
Preclinical and clinical results with the natural marine product ET-743
2003
Trabectedin (Et-743): Evaluation of Its Use In Advanced Soft-Tissue Sarcoma
2007
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
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Basic Guide to the Mechanisms of Antiestrogen Action
1998
TISSUES 2.0: an integrative web resource on mammalian tissue expression
2018
Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?
1999 Standout
The occurrence of tricin and its derivatives in plants
2016
Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator
2003 Standout
Descending Pathways in Motor Control
2008 Standout
Future of ToxicologyMechanisms of Toxicity and Drug Safety: Where Do We Go from Here?
2006
Hypoxia-Inducible Factor 1 and Cardiovascular Disease
2013 StandoutNobel
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes
2002 Standout
Rice - not just a staple food: A comprehensive review on its phytochemicals and therapeutic potential
2020
Trace determination of tamoxifen and 5-fluorouracil in hospital and urban wastewaters
2006
Distinct Properties and Advantages of a Novel Peroxisome Proliferator-Activated Protein γ Selective Modulator
2003
Analysis of Flavonoid Metabolites in Buckwheat Leaves Using UPLC-ESI-MS/MS
2019
Detection of Metabolic Alterations in Non-tumor Gastrointestinal Tissue of the ApcMin/+ Mouse by 1H MAS NMR Spectroscopy
2009
Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
2012 Standout
The PPARs: From Orphan Receptors to Drug Discovery
2000 Standout
The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest
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STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
2018 Standout
Metabolic reprogramming and cancer progression
2020 StandoutScience
Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia
2004
Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis
2013
Delayed Adverse Effects of Neonatal Exposure to Diethylstilbestrol and Their Dose Dependency in Female Rats
2011
Molecular Mechanisms of Myocardial Remodeling
1999 Standout
A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program
1997
Rationale and Application of Fatty Acid Oxidation Inhibitors in Treatment of Diabetes Mellitus
1992
Water-resistant porous coordination polymers for gas separation
2016 StandoutNobel
Works of Peter Greaves being referenced
Fra-1 controls motility of bladder cancer cells via transcriptional upregulation of the receptor tyrosine kinase AXL
2011
First dose of potential new medicines to humans: how animals help
2004
Metabolic profiling of transgenic adenocarcinoma of mouse prostate (TRAMP) Tissue by 1H‐NMR analysis: evidence for unusual phospholipid metabolism
2008
Uroporphyria and hepatic carcinogenesis induced by polychlorinated biphenyls–iron interaction: Absence in the Cyp1a2(−/−) knockout mouse
2005
Comparison of four modulators of drug metabolism as protectants against the hepatotoxicity of the novel antitumor drug yondelis (ET-743) in the female rat and in hepatocytes in vitro
2004
Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy
2015
Hepatic Gene Expression in Protoporphyic Fech Mice Is Associated with Cholestatic Injury but Not a Marked Depletion of the Heme Regulatory Pool
2005
Comparisons of the effects of tamoxifen, toremifene and raloxifene on enzyme induction and gene expression in the ovariectomised rat uterus
2001
Growth-inhibitory and cell cycle-arresting properties of the rice bran constituent tricin in human-derived breast cancer cells in vitro and in nude mice in vivo
2004
Androgen manipulation alters oxidative DNA adduct levels in androgen-sensitive prostate cancer cells grown in vitro and in vivo
2007
Determination of 8‐oxo‐2′‐deoxyguanosine and creatinine in murine and human urine by liquid chromatography/tandem mass spectrometry: application to chemoprevention studies
2008
Dietary agent indole‐3‐carbinol protects female rats against the hepatotoxicity of the antitumor drug ET‐743 (trabectidin) without compromising efficacy in a rat mammary carcinoma
2004
Preliminary safety evaluation of the putative cancer chemopreventive agent tricin, a naturally occurring flavone
2005
Adenomyosis—A Result of Disordered Stromal Differentiation
2001
Hepatobiliary damage and changes in hepatic gene expression caused by the antitumor drug ecteinascidin-743 (ET-743) in the female rat.
2002
Cardiac Hypertrophy in the Dog and Rat Induced by Oxfenicine, an Agent Which Modifies Muscle Metabolism
1984
Breast Cancer Prevention by Green Tea Catechins and Black Tea Theaflavins in the C3(1) SV40 T,t Antigen Transgenic Mouse Model Is Accompanied by Increased Apoptosis and a Decrease in Oxidative DNA Adducts
2007
Neonatal tamoxifen treatment of mice leads to adenomyosis but not uterine cancer
2005
Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats.
1993
Altered Patterns of Mucin Secretion in Gastric Hyperplasia in Mice
1984
The rice bran constituent tricin potently inhibits cyclooxygenase enzymes and interferes with intestinal carcinogenesis in ApcMin mice
2005
Complete protection by high-dose dexamethasone against the hepatotoxicity of the novel antitumor drug yondelis (ET-743) in the rat.
2003
Hepatic Foci of Cellular and Enzymatic Alteration and Nodules in Rats Treated With Clofibrate or Diethylnitrosamine Followed by Phenobarbital: Their Rate of Onset and Their Reversibility
1986
Preclinical Colorectal Cancer Chemopreventive Efficacy and p53-Modulating Activity of 3′,4′,5′-Trimethoxyflavonol, a Quercetin Analogue
2010
Coronary hyperemia and cardiac hypertrophy following inhibition of fatty acid oxidation. Evidence of a regulatory role for cytosolic phosphorylation potential.
1985