Citation Impact
Citing Papers
Mechanism of IFN-γ-induced Endocytosis of Tight Junction Proteins: Myosin II-dependent Vacuolarization of the Apical Plasma Membrane
2005
Transient Ablation of Regulatory T cells Improves Antitumor Immunity in Colitis-Associated Colon Cancer
2014 StandoutNobel
Tricellulin Forms a Barrier to Macromolecules in Tricellular Tight Junctions without Affecting Ion Permeability
2009
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)
2013 StandoutNobel
Tralokinumab for moderate-to-severe UC: a randomised, double-blind, placebo-controlled, phase IIa study
2014
AMP-activated Protein Kinase Mediates the Interferon-γ-induced Decrease in Intestinal Epithelial Barrier Function
2009
HIV-1 gp120 Induces TLR2- and TLR4-Mediated Innate Immune Activation in Human Female Genital Epithelium
2013
Experimental Models of Inflammatory Bowel Diseases
2015
Modification of Tight Junction Structure and Permeability by Nutritional Means
2009
Cytokines in inflammatory bowel disease
2014 Standout
Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in coeliac disease
2011
Lack of association of MYO9B genetic variants with coeliac disease in a British cohort
2006
Occludin Phosphorylation and Ubiquitination Regulate Tight Junction Trafficking and Vascular Endothelial Growth Factor-induced Permeability
2009
Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease
2011
IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn’s disease
2008
Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis
2013 Standout
Epithelial Myosin Light Chain Kinase Activation Induces Mucosal Interleukin-13 Expression to Alter Tight Junction Ion Selectivity
2010
Necroptosis and its role in inflammation
2015 StandoutNature
The Blood–Brain Barrier
2015 Standout
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
Ulcerative Colitis
2011 Standout
Tumor Necrosis Factor-induced Long Myosin Light Chain Kinase Transcription Is Regulated by Differentiation-dependent Signaling Events
2006
Suppression of inflammation in ulcerative colitis by interferon-β-1a is accompanied by inhibition of IL-13 production
2010
The role of IL-13 and NK T cells in experimental and human ulcerative colitis
2008
Conceptual barriers to understanding physical barriers
2015
Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells
2010 StandoutNobel
Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease
2015
Periluminal Distribution of HIV-Binding Target Cells and Gp340 in the Oral, Cervical and Sigmoid/Rectal Mucosae: A Mapping Study
2015 StandoutNobel
Interferon-γ Regulates Intestinal Epithelial Homeostasis through Converging β-Catenin Signaling Pathways
2010
R5 HIV‐1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR5
2013
Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4
2017 StandoutNobel
Interleukin-13 Activates Distinct Cellular Pathways Leading to Ductular Reaction, Steatosis, and Fibrosis
2016
Inflammatory bowel disease: clinical aspects and established and evolving therapies
2007 Standout
Crohn's disease
2012 Standout
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
2009 Standout
The role of molecular remodeling in differential regulation of tight junction permeability
2014
Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis
2008
Role of peroxisome proliferator-activated receptor-α in ileum tight junction alteration in mouse model of restraint stress
2009
Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease
2006
Differential Phosphorylation of Occludin and Tricellulin by CK2 and CK1
2009
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
2006 Standout
IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation
2016
Inflammatory bowel disease: cause and immunobiology
2007 Standout
Differential regulation of interleukin 17 and interferon production in inflammatory bowel disease
2009
Inflammatory Bowel Disease
2009 Standout
TNFα up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling
2009
New therapies for inflammatory bowel disease: from the bench to the bedside
2011
The role of transcription-independent damage signals in the initiation of epithelial wound healing
2013
Metagenomic biomarker discovery and explanation
2011 Standout
Roles of Rho/ROCK and MLCK in TNF‐α‐induced changes in endothelial morphology and permeability
2007
Asthma
2017 Standout
LIGHT Signals Directly to Intestinal Epithelia to Cause Barrier Dysfunction via Cytoskeletal and Endocytic Mechanisms
2007
Diabetic Retinopathy
2012 Standout
Microbial Influences in Inflammatory Bowel Diseases
2008
Ulcerative colitis
2012 Standout
Crohn's disease
2016 Standout
Autophagy in the Pathogenesis of Disease
2008 Standout
Ankylosing spondylitis
2007 Standout
The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation
2010
Probiotic Escherichia coli Nissle 1917 Inhibits Leaky Gut by Enhancing Mucosal Integrity
2007
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease
2006
Blocking IL-25 signalling protects against gut inflammation in a type-2 model of colitis by suppressing nuocyte and NKT derived IL-13
2012
Targeting immune cell circuits and trafficking in inflammatory bowel disease
2019
Intestinal mucosal barrier function in health and disease
2009 Standout
Regulation of intestinal epithelial permeability by tight junctions
2012 Standout
TLR2-Induced Calpain Cleavage of Epithelial Junctional Proteins Facilitates Leukocyte Transmigration
2009
Intestinal Permeability Defects: Is It Time to Treat?
2013
Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation
2008
TNFR2 Activates MLCK-Dependent Tight Junction Dysregulation to Cause Apoptosis-Mediated Barrier Loss and Experimental Colitis
2013
A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion
2008
Disrupted Barrier Function through Epithelial Cell Apoptosis
2006
Claudin-3 acts as a sealing component of the tight junction for ions of either charge and uncharged solutes
2010
Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma
2014 Standout
Ulcerative colitis
2016 Standout
The intestinal epithelial barrier: a therapeutic target?
2016 Standout
Casein kinase Iε associates with and phosphorylates the tight junction protein occludin
2006
Tricellulin forms homomeric and heteromeric tight junctional complexes
2010
Asthma phenotypes: the evolution from clinical to molecular approaches
2012 Standout
TH9 cells that express the transcription factor PU.1 drive T cell–mediated colitis via IL-9 receptor signaling in intestinal epithelial cells
2014
Mend Your Fences
2017
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
2007 StandoutNatureNobel
Barrier Effects of Nutritional Factors
2009
Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders
2013 Standout
Transforming Growth Factor-β, a Whey Protein Component, Strengthens the Intestinal Barrier by Upregulating Claudin-4 in HT-29/B6 Cells1,2
2011
IFN-γ-Induced TNFR2 Expression Is Required for TNF-Dependent Intestinal Epithelial Barrier Dysfunction
2006
IL-13Rα2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice
2007
Negative Regulation of Hypoxic Responses via Induced Reptin Methylation
2010 StandoutNobel
Ulcerative colitis
2020 Standout
A microbial symbiosis factor prevents intestinal inflammatory disease
2008 StandoutNature
Epithelial transport and barrier function in occludin-deficient mice
2005
Role of claudins in tumorigenesis
2005
Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Protective and pathogenic functions of macrophage subsets
2011 Standout
Hormone Therapy Increases Risk of Ulcerative Colitis but not Crohn's Disease
2012
XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease
2008 Standout
PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques
2012
Tricellulin is regulated via interleukin-13-receptor α2, affects macromolecule uptake, and is decreased in ulcerative colitis
2017
Exploring the full spectrum of macrophage activation
2008 Standout
The Link between the Appendix and Ulcerative Colitis: Clinical Relevance and Potential Immunological Mechanisms
2015
Proinflammatory Cytokines in the Pathogenesis of Inflammatory Bowel Diseases
2011
Interleukin-6 (IL-6) Regulates Claudin-2 Expression and Tight Junction Permeability in Intestinal Epithelium
2011
Proinflammatory cytokines tumor necrosis factor-α and interferon-γ alter tight junction structure and function in the rat parotid gland Par-C10 cell line
2008
Quercetin Enhances Epithelial Barrier Function and Increases Claudin-4 Expression in Caco-2 Cells3
2008
Epithelial apoptosis is a prominent feature of the epithelial barrier disturbance in intestinal inflammation: effect of pro-inflammatory interleukin-13 on epithelial cell function
2008
Molecular Basis of Epithelial Barrier Regulation
2006
Infliximab for Induction and Maintenance Therapy for Ulcerative Colitis
2005 Standout
Tight Junction Pore and Leak Pathways: A Dynamic Duo
2011
Role of cytokines in inflammatory bowel disease
2008
The Th17 Pathway and Inflammatory Diseases of the Intestines, Lungs, and Skin
2011
Advances in skin grafting and treatment of cutaneous wounds
2014 StandoutScience
HIV infection and the gastrointestinal tract
2005
The histidine triad protein Hint1 interacts with Pontin and Reptin and inhibits TCF–β-catenin-mediated transcription
2005
Claudin-2-dependent paracellular channels are dynamically gated
2015
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
2008 Standout
Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function
2011
Immunopathology of schistosomiasis
2006
Splicing Diversity of the Human OCLN Gene and Its Biological Significance for Hepatitis C Virus Entry
2010 StandoutNobel
Proinflammatory Cytokines Disrupt Epithelial Barrier Function by Apoptosis-Independent Mechanisms
2003
JAK inhibition using tofacitinib for inflammatory bowel disease treatment: a hub for multiple inflammatory cytokines
2015
Decline in intestinal mucosal IL-10 expression and decreased intestinal barrier function in a mouse model of total parenteral nutrition
2007
Absence of a role for interleukin‐13 in inflammatory bowel disease
2013
Epithelial Barriers in Homeostasis and Disease
2010
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
IL-1β Causes an Increase in Intestinal Epithelial Tight Junction Permeability
2007
Cell Death and Inflammatory Bowel Diseases: Apoptosis, Necrosis, and Autophagy in the Intestinal Epithelium
2014
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure
2006
Interferon-γ Inhibits T84 Epithelial Cell Migration by Redirecting Transcytosis of β1 Integrin from the Migrating Leading Edge
2005
Works of Peter Florian being referenced
Supernatants of HIV-infected immune cells affect the barrier function of human HT-29/B6 intestinal epithelial cells
2002
Claudins in the tight junctions of stria vascularis marginal cells
2003
Gene expression of the tight junction protein occludin includes differential splicing and alternative promoter usage
2002
Single‐cell epithelial defects close rapidly by an actinomyosin purse string mechanism with functional tight junctions
2002
Contribution of claudin-5 to barrier properties in tight junctions of epithelial cells
2005
Restitution of single-cell defects in the mouse colon epithelium differs from that of cultured cells
2006
Interleukin-13 Is the Key Effector Th2 Cytokine in Ulcerative Colitis That Affects Epithelial Tight Junctions, Apoptosis, and Cell Restitution
2005
Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure
2005
The specific fates of tight junction proteins in apoptotic epithelial cells
2004
Interleukin-13 Is the Key Effector Th2 Cytokine in Ulcerative Colitis That Affects Epithelial Tight Junctions, Apoptosis, and Cell Restitution
2005
Cytokine-dependent transcriptional down-regulation of epithelial sodium channel in ulcerative colitis
2004