Citation Impact
Citing Papers
The human disease network
2007 Standout
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
A phytol-enriched diet induces changes in fatty acid metabolism in mice both via PPARα-dependent and -independent pathways
2005
Thiazolidinediones
2004 Standout
(d)-β-Hydroxybutyrate Inhibits Adipocyte Lipolysis via the Nicotinic Acid Receptor PUMA-G
2005
15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
1995 Standout
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
1998 StandoutNature
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
1990 StandoutNature
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
2002 StandoutNature
Ligand-induced Peroxisome Proliferator-activated Receptor α Conformational Change
1997
The metabolic syndrome
2010 Standout
The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation
1996
Characteristics and roles of the volume-sensitive outwardly rectifying (VSOR) anion channel in the central nervous system
2014
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Trans Fatty Acids and Cardiovascular Disease
2006 Standout
Regulation of ketogenesis and the renaissance of carnitine palmitoyltransferase
1989
Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline
2016 Standout
Functional genomics: the search for novel neurotransmitters and neuropeptides
1998
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis
2000 Standout
Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.
1994
Mechanically Activated Ion Channels
2015 StandoutNobel
Altered Constitutive Expression of Fatty Acid-metabolizing Enzymes in Mice Lacking the Peroxisome Proliferator-activated Receptor α (PPARα)
1998
Mitochondrial Carnitine Palmitoyltransferase I Isoform Switching in the Developing Rat Heart
1995
The metabolic syndrome
2005 Standout
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Farnesylation of Pex19p is not essential for peroxisome biogenesis in yeast and mammalian cells
2006
Central nervous system control of food intake
2000 StandoutNature
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Dynamics and functions of lipid droplets
2018 Standout
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
2016 Standout
Stem Cell-derived Neural Stem/Progenitor Cell Supporting Factor Is an Autocrine/Paracrine Survival Factor for Adult Neural Stem/Progenitor Cells
2003 StandoutNobel
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
2004 StandoutNature
Fibrate induction of the adrenoleukodystrophy‐related gene (ABCD2)
2001
Inhibition of Carnitine Palmitoyltransferase I Augments Sphingolipid Synthesis and Palmitate-induced Apoptosis
1997 StandoutNobel
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Liver-specific disruption of PPARγ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes
2003
A 48-hour Lipid Infusion in the Rat Time-Dependently Inhibits Glucose-Induced Insulin Secretion and B Cell Oxidation Through a Process Likely Coupled to Fatty Acid Oxidation*
1990
Peroxisome biogenesis: from yeast to man
1998
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
2009
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Roles of PPARs in health and disease
2000 StandoutNature
Diet, fatty acids, and regulation of genes important for heart disease
2004
Intensive Insulin Therapy in the Medical ICU
2006 Standout
Human disorders of cortical development: from past to present
2006
Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients
2005
Peroxisomal protein PEX 13 functions in selective autophagy
2016
Accumulation of triacylglycerol in cultured rat hepatocytes is increased by ethanol and by insulin and dexamethasone
1983
Biosynthesis of the Caenorhabditis elegans dauer pheromone
2009 StandoutNobel
A Role for Sphingolipids in Producing the Common Features of Type 2 Diabetes, Metabolic Syndrome X, and Cushing’s Syndrome
2005
Orphan Nuclear Receptors: From Gene to Function*
1999
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
The Enzymes, Regulation, and Genetics of Bile Acid Synthesis
2003 Standout
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships.
1994
Malonyl-CoA binding site and the overt carnitine palmitoyltransferase activity reside on the opposite sides of the outer mitochondrial membrane.
1987
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum
2010 StandoutNobel
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS: A Nuclear Receptor Signaling Pathway in Lipid Physiology
1996
Inhibition of hepatic fatty acid oxidation at carnitine palmitoyltransferase I by the peroxisome proliferator 2-hydroxy-3-propyl-4-[6-(tetrazol-5-yl) hexyloxy]acetophenone
1988
Peroxisome biogenesis disorders: Biological, clinical and pathophysiological perspectives
2013
Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels
1999
Pleiotropic Actions of Peroxisome Proliferator–Activated Receptors in Lipid Metabolism and Atherosclerosis
2002
Inverse Relationship Between Cytotoxicity of Free Fatty Acids in Pancreatic Islet Cells and Cellular Triglyceride Accumulation
2001
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ
1997 Standout
PEROXISOMAL β-OXIDATION AND PEROXISOME PROLIFERATOR –ACTIVATED RECEPTOR α: An Adaptive Metabolic System
2001
Distribution of nociceptin/orphanin FQ precursor protein and receptor in brain and spinal cord: A study using in situ hybridization and X-gal histochemistry in receptor-deficient mice
2000
Peroxisome Biogenesis Disorders
2003
Liver-specific disruption of PPARγ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes
2003
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ
1997 Standout
Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression.
1996
The gut microbiota as an environmental factor that regulates fat storage
2004 Standout
Malonyl-CoA-sensitive and -insensitive carnitine palmitoyltransferase activities of microsomes are due to different proteins
1994
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.
1990 Standout
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*
1999 Standout
Rat heart expresses two forms of mitochondrial carnitine palmitoyltransferase I. The minor component is identical to the liver enzyme.
1994
Targeted Disruption of the α Isoform of the Peroxisome Proliferator-Activated Receptor Gene in Mice Results in Abolishment of the Pleiotropic Effects of Peroxisome Proliferators
1995
Fatty acid oxidation affects food intake by altering hepatic energy status
1999
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
NFATc3 and NFATc4 Are Required for Cardiac Development and Mitochondrial Function
2003
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1999 StandoutNature
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
Triglyceride accumulation protects against fatty acid-induced lipotoxicity
2003 Standout
Development and initial evaluation of a novel method for assessing tissue-specific plasma free fatty acid utilization in vivo using (R)-2-bromopalmitate tracer
1999
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Works of Peter Declercq being referenced
The peroxisome proliferator activated receptor regulates malic enzyme gene expression.
1994
Docosahexaenoic Acid Deficit Is Not a Major Pathogenic Factor in Peroxisome-Deficient Mice
2000
Mitochondrial Alterations Caused by Defective Peroxisomal Biogenesis in a Mouse Model for Zellweger Syndrome (PEX5 Knockout Mouse)
2001
D,L-3-hydroxybutyrate treatment of multiple acyl-CoA dehydrogenase deficiency (MADD)
2003
A mouse model for Zellweger syndrome
1997
Isoprenoid biosynthesis is not compromised in a Zellweger syndrome mouse model
2001
Do sphingoid bases interact with the peroxisome proliferator activated receptor α (PPAR-α)?
2000
Antagonism of COUP-TF and PPARα-RXRα on the Activation of the Malic Enzyme Gene Promoter: Modulation by 9-cis-RA
1995
Absence of peroxisomes in mouse hepatocytes causes mitochondrial and ER abnormalities†
2005
Inactivation of the Peroxisomal Multifunctional Protein-2 in Mice Impedes the Degradation of Not Only 2-Methyl-branched Fatty Acids and Bile Acid Intermediates but Also of Very Long Chain Fatty Acids
2000
DNA Binding Preferences of PPARα/RXRα Heterodimers
1997
Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse
2001
Swelling-activated efflux of taurine and other organic osmolytes in endothelial cells
1997
Characterization of the mitochondrial carnitine palmitoyltransferase enzyme system. I. Use of inhibitors.
1987
Reduced Cortisol Metabolism During Critical Illness
2014
Interaction of malonyl-CoA and 2-tetradecylglycidyl-CoA with mitochondrial carnitine palmitoyltransferase I.
1985
Role of glycerol 3-phosphate and glycerophosphate acyltransferase in the nutritional control of hepatic triacylglycerol synthesis
1982
Glycerol‐3‐phosphate content and triacylglycerol synthesis in isolated hepatocytes from fed and starved rats
1981