Citation Impact
Citing Papers
Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins
2008 StandoutNobel
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans
2012 StandoutNobel
Identification of a physiological E2 module for the human anaphase-promoting complex
2009
MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
2007 StandoutScience
Single, context-specific glycans can target misfolded glycoproteins for ER-associated degradation
2005
Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane
2005
Peptides Encoded by Short ORFs Control Development and Define a New Eukaryotic Gene Family
2007
Role of Gab1 in Heart, Placenta, and Skin Development and Growth Factor- and Cytokine-Induced Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Activation
2000
The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein–protein interactions
1996
Degradation of unassembled Vph1p reveals novel aspects of the yeast ER quality control system
2000
The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch
1989 StandoutNatureNobel
Inflammation and metabolic disorders
2006 StandoutNature
The Ubiquitin-Proteasome Pathway Mediates the Regulated Degradation of Mammalian 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase
2000
Voltage-Gated Sodium Channels: Mutations, Channelopathies and Targets
2011
A novel mammalian endoplasmic reticulum ubiquitin ligase homologous to the yeast Hrd1
2003 StandoutNobel
Modular regulatory principles of large non-coding RNAs
2012 StandoutNature
Identification of an Atypical Grb2 Carboxyl-terminal SH3 Domain Binding Site in Gab Docking Proteins Reveals Grb2-dependent and -independent Recruitment of Gab1 to Receptor Tyrosine Kinases
2000
Guidance of Cell Migration by the Drosophila PDGF/VEGF Receptor
2001
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Distinct Machinery Is Required in Saccharomyces cerevisiae for the Endoplasmic Reticulum-associated Degradation of a Multispanning Membrane Protein and a Soluble Luminal Protein
2004
Human HRD1 protects against ER stress‐induced apoptosis through ER‐associated degradation1
2002
Autophagy regulates lipid metabolism
2009 StandoutNature
The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA
1997 StandoutNobel
Daughter of Sevenless Is a Substrate of the Phosphotyrosine Phosphatase Corkscrew and Functions during Sevenless Signaling
1996
Heterochronic Genes Control Cell Cycle Progress and Developmental Competence of C. elegans Vulva Precursor Cells
1996 StandoutNobel
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
2000 StandoutNatureNobel
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
Endoplasmic reticulum-associated protein degradation
2000
Protein Quality Control in the Cytosol and the Endoplasmic Reticulum: Brothers in Arms
2010
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
1993 StandoutNobel
Rho GTPases in cell biology
2002 StandoutNature
Analysis of Temperature-Sensitive Mutants Reveals New Genes Involved in the Courtship Song of Drosophila
1998 StandoutNobel
The antibacterial arm of the Drosophila innate immune response requires an IκB kinase
2001
Peroxisomal protein import and ERAD: variations on a common theme
2010
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Der1p, a protein required for degradation of malfolded soluble proteins of the endoplasmic reticulum: topology and Der1-like proteins
2004
Voltage-gated sodium channel modulation by scorpion α-toxins
2006
Human microcephaly
2004
Two Signals Are Necessary for Cell Proliferation Induced by a Cytokine Receptor gp130: Involvement of STAT3 in Anti-Apoptosis
1996 Standout
A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans
1989 StandoutNobel
A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a
2014
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
The ‘Gab’ in signal transduction
2003
Multiubiquitin Chain Receptors Define a Layer of Substrate Selectivity in the Ubiquitin-Proteasome System
2004
The immune response of Drosophila
2003 StandoutNatureNobel
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Protein dislocation from the ER
2010
Retrograde protein translocation: ERADication of secretory proteins in health and disease
1999
A membrane protein required for dislocation of misfolded proteins from the ER
2004 Nature
Met, metastasis, motility and more
2003 Standout
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
1993 StandoutNobel
Proteolytic and lipolytic responses to starvation
2006
ERAD: the long road to destruction
2005
From Form to Function: Signaling by Protein Tyrosine Phosphatases
1996
ER-associated degradation in protein quality control and cellular regulation
2002
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites
1995 StandoutNobel
Three-dimensional segregation of supramolecular activation clusters in T cells
1998 StandoutNature
A switch from p130Cas/Crk to Gab1/Crk signaling correlates with anchorage independent growth and JNK activation in cells transformed by the Met receptor oncoprotein
2000
The role of sdc-1 in the sex determination and dosage compensation decisions in Caenorhabditis elegans.
1990
Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis
1996 Nature
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
2008 StandoutNature
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Endoplasmic Reticulum Stress Signaling in Disease
2006
Jupiter, a newDrosophila protein associated with microtubules
2006
Membrane Topology of the Yeast Endoplasmic Reticulum-localized Ubiquitin Ligase Doa10 and Comparison with Its Human Ortholog TEB4 (MARCH-VI)
2005
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
2009 StandoutNature
Alternative temporal control systems for hypodermal cell differentiation in Caenorhabditis elegans
1991 StandoutNatureNobel
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
2004 Nature
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
2001 StandoutNatureNobel
Cloning and characterization of a calcium channel alpha 1 subunit from Drosophila melanogaster with similarity to the rat brain type D isoform
1995
PAG-3, a Zn-finger transcription factor, determines neuroblast fate inC. elegans
2002 StandoutNobel
A gp330/megalin-related protein is required in the major epidermis ofCaenorhabditis elegansfor completion of molting
1999
The Gab1 PH Domain Is Required for Localization of Gab1 at Sites of Cell-Cell Contact and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase
1999
Coupling of Gab1 to C-Met, Grb2, and Shp2 Mediates Biological Responses
2000
Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of Caenorhabditis elegans
2018 StandoutNobel
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
1997 StandoutScience
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
The IRS-signalling system: A network of docking proteins that mediate insulin action
1998
Integrin Signaling
1999 StandoutScience
Cholera Toxin Is Exported from Microsomes by the Sec61p Complex
2000
Processing of Human Cytomegalovirus UL37 Mutant Glycoproteins in the Endoplasmic Reticulum Lumen prior to Mitochondrial Importation
2006
TheDrosophila ergK+Channel Polypeptide Is Encoded by the Seizure Locus
1997
The Caenorhabditis elegans EGL-15 Signaling Pathway Implicates a DOS-Like Multisubstrate Adaptor Protein in Fibroblast Growth Factor Signal Transduction
2001
Regulation of Early Events in Integrin Signaling by Protein Tyrosine Phosphatase SHP-2
1999
AAA-ATPase p97/Cdc48p, a Cytosolic Chaperone Required for Endoplasmic Reticulum-Associated Protein Degradation
2002
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Genetic interactions affecting touch sensitivity in Caenorhabditis elegans.
1996 StandoutNobel
PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer
1997 StandoutScience
The Png1–Rad23 complex regulates glycoprotein turnover
2006
Essential Role of Gab1 for Signaling by the C-Met Receptor in Vivo
2000
Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control
2004
Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline
2010 StandoutNobel
The lin-14 locus of Caenorhabditis elegans controls the time of expression of specific postembryonic developmental events.
1987 StandoutNobel
The IRS-signalling system: A network of docking proteins that mediate insulin action
1998
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
The function of the Drosophila fat facets deubiquitinating enzyme in limiting photoreceptor cell number is intimately associated with endocytosis
2000
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
Basic Leucine Zipper Protein Cnc-C Is a Substrate and Transcriptional Regulator of the Drosophila 26S Proteasome
2010
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
2011 StandoutNobel
Protein Translocation Across Biological Membranes
2005 StandoutScienceNobel
Htm1p, a mannosidase‐like protein, is involved in glycoprotein degradation in yeast
2001
Works of Péter Deák being referenced
Cloning and functional analysis of tipE, a novel membrane protein that enhances drosophila para sodium channel function
1995
Use of Modular Substrates Demonstrates Mechanistic Diversity and Reveals Differences in Chaperone Requirement of ERAD
2003
Re‐entering the translocon from the lumenal side of the endoplasmic reticulum. Studies on mutated carboxypeptidase yscY species
1999
DOS, a Novel Pleckstrin Homology Domain–Containing Protein Required for Signal Transduction between Sevenless and Ras1 in Drosophila
1996
Membrane Topology and Function of Der3/Hrd1p as a Ubiquitin-Protein Ligase (E3) Involved in Endoplasmic Reticulum Degradation
2001
The E2-C Vihar Is Required for the Correct Spatiotemporal Proteolysis of Cyclin B and Itself Undergoes Cyclical Degradation
2004
Genetic interactions of Hrd3p and Der3p/Hrd1p with Sec61p suggest a retro-translocation complex mediating protein transport for ER degradation
1999
Molecular characterization of a conserved, guanine nucleotide-dependent ADP-ribosylation factor in Drosophila melanogaster
1993
Orbit, a Novel Microtubule-Associated Protein Essential for Mitosis inDrosophila melanogaster
2000
mini spindles
1999
P-Element Insertion Alleles of Essential Genes on the Third Chromosome of Drosophila melanogaster Correlation of Physical and Cytogenetic Maps in Chromosomal Region 86E-87F
1997
Metaphase Arrest with Centromere Separation in polo Mutants of Drosophila
2001
Deletion of proteasomal subunit S5a/Rpn10/p54 causes lethality, multiple mitotic defects and overexpression of proteasomal genes inDrosophila melanogaster
2003
The isolation and genetic analysis of aCaenorhabditis elegants translocation (szT1) strain bearing an X-chromosome balancer
1985
TheseizureLocus Encodes theDrosophilaHomolog of the HERG Potassium Channel
1997
P-Element Insertion Alleles of Essential Genes on the Third Chromosome of Drosophila melanogaster: Mutations Affecting Embryonic PNS Development
1997