Citation Impact

Citing Papers

Indocyanine Green Nanoparticles Useful for Photomedicine
2006
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
Diterpenes from European Euphorbia Species Serving as Prototypes for Natural‐Product‐Based Drug Discovery
2012
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Arresting a Transient Receptor Potential (TRP) Channel
2010 StandoutNobel
The development and characterisation of porphyrin isothiocyanate–monoclonal antibody conjugates for photoimmunotherapy
2005
Involvement of the Acid Sphingomyelinase Pathway in UVA-induced Apoptosis
2001
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Photosensitiser delivery for photodynamic therapy. Part 2: systemic carrier platforms
2008
Intraperitoneal Photodynamic Therapy
2007
Multifunctional Lipid/Quantum Dot Hybrid Nanocontainers for Controlled Targeting of Live Cells
2006 StandoutNobel
Necroptosis and its role in inflammation
2015 StandoutNature
Immunogenic cell death, DAMPs and anticancer therapeutics: An emerging amalgamation
2009
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding
2007
The role of apoptosis in response to photodynamic therapy: what, where, why, and how
2002
Mechanisms involved in the cell cycle and apoptosis of HT-29 cells pre-treated with MK-886 prior to photodynamic therapy with hypericin
2008
Catalytic Three‐Component Ugi Reaction
2008 StandoutNobel
Natural products: An evolving role in future drug discovery
2011 Standout
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
The biology and management of non-small cell lung cancer
2018 StandoutNature
Downregulation of ICAM-1 and VCAM-1 expression in endothelial cells treated by photodynamic therapy
2004
Prognostic and Predictive Value of DAMPs and DAMP-Associated Processes in Cancer
2015
Clinical development and potential of photothermal and photodynamic therapies for cancer
2020 Standout
Transport Of Surface‐Modified Nanoparticles Through Cell Monolayers
2005
Evaluation of Hypericin: Effect of Aggregation on Targeting Biodistribution
2014
Liposomes for photodynamic therapy
2003
WITHDRAWN: Hypericin-based Photodynamic Therapy Induces a Tumor-Specific Immune Response and an Effective DC-based cancer Immunotherapy
2014
Deficiency in Apoptotic Effectors BAX and BAK Reveals an Autophagic Cell Death Pathway Initiated by Photodamage to the Endoplasmic Reticulum
2006
Transcriptional Induction of Mitogen-activated Protein Kinase Phosphatase 1 by Retinoids
2002
siRNA‐mediated Knockdown of the Heme Synthesis and Degradation Pathways: Modulation of Treatment Effect of 5‐Aminolevulinic Acid‐based Photodynamic Therapy in Urothelial Cancer Cell Lines
2009
Megalin-targeting liposomes for placental drug delivery
2020
Molecular effectors of multiple cell death pathways initiated by photodynamic therapy
2007
State of the art in the delivery of photosensitizers for photodynamic therapy
2002
Assessing autophagy in the context of photodynamic therapy
2010
Multimodal immunogenic cancer cell death as a consequence of anticancer cytotoxic treatments
2013
Immunogenic cell death in cancer and infectious disease
2016 Standout
BCL-2 family proteins: changing partners in the dance towards death
2017
Inducers of immunogenic cancer cell death
2013
Effects of Moderate Alcohol Consumption on the Central Nervous System*
1998
Apoptotic cell clearance: basic biology and therapeutic potential
2014
Immune Response Against Angiosarcoma Following Lower Fluence Rate Clinical Photodynamic Therapy
2008
Regulatory pathways in photodynamic therapy induced apoptosis
2004
ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death
2013
EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages
2011
Ectopic Expression of Nonliganded Retinoic Acid Receptor β Abrogates AP-1 Activity by Selective Degradation of c-Jun in Cervical Carcinoma Cells
2004 StandoutNobel
Mechanism of Action of Conventional and Targeted Anticancer Therapies: Reinstating Immunosurveillance
2013
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance
2013
Enhancing the therapeutic responsiveness of photodynamic therapy with the antiangiogenic agents SU5416 and SU6668 in murine nasopharyngeal carcinoma models
2005
Recent advances with liposomes as pharmaceutical carriers
2005 Standout
Rose Bengal Acetate PhotoDynamic Therapy (RBAc-PDT) Induces Exposure and Release of Damage-Associated Molecular Patterns (DAMPs) in Human HeLa Cells
2014
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
Transferrin conjugation does not increase the efficiency of liposomal Foscan during in vitro photodynamic therapy of oesophageal cancer
2012
Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity
2016
Fluorescent Nanorods and Nanospheres for Real‐Time In Vivo Probing of Nanoparticle Shape‐Dependent Tumor Penetration
2011 StandoutNobel
Photodynamic therapy and anti-tumour immunity
2006 Standout
Molecular profiling of angiogenesis in hypericin mediated photodynamic therapy
2008
The immunological consequences of photodynamic treatment of cancer, a literature review
2003
Contribution of RIP3 and MLKL to immunogenic cell death signaling in cancer chemotherapy
2016
Mechanisms in photodynamic therapy: part two—cellular signaling, cell metabolism and modes of cell death
2005
Signaling pathways in cell death and survival after photodynamic therapy
2000
Photodynamic therapy with fullerenes
2007
Self-assembled liposomal nanoparticles in photodynamic therapy
2013
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
The effect of photodynamic therapy on tumor angiogenesis
2009
RPE lipofuscin and its role in retinal pathobiology
2005
A novel chlorin–PEG–folate conjugate with higher water solubility, lower cytotoxicity, better tumor targeting and photodynamic activity
2013
Photodynamic therapy of cancer: An update
2011 Standout
Hypericin-mediated photodynamic therapy in combination with Avastin (bevacizumab) improves tumor response by downregulating angiogenic proteins
2007
Synthesis of estradiol-pheophorbide a conjugates: evidence of nuclear targeting, DNA damage and improved photodynamic activity in human breast cancer and vascular endothelial cells
2006
Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin
2011
Light-sensitive lipid-based nanoparticles for drug delivery: design principles and future considerations for biological applications
2010
Domain-dependent Photodamage to Bcl-2
2003
Mechanisms in photodynamic therapy: part one—photosensitizers, photochemistry and cellular localization
2004 Standout
Ligand-targeted therapeutics in anticancer therapy
2002
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Photodynamic Therapy of Skin Cancers: Sensitizers, Clinical Studies and Future Directives
2000
The potential application of chlorin e6—polyvinylpyrrolidone formulation in photodynamic therapy
2006
Photodynamic therapy in urology: What can we do now and where are we heading?
2012
Mechanisms in photodynamic therapy: Part three—Photosensitizer pharmacokinetics, biodistribution, tumor localization and modes of tumor destruction
2005
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
Development and applications of photo-triggered theranostic agents
2010
Photochemical internalization of tumor-targeted protein toxins
2011
Liposomal nanostructures for photosensitizer delivery
2011
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Preparation of PEG-conjugated fullerene containing Gd3+ ions for photodynamic therapy
2006
Combinatorial Strategies for the Induction of Immunogenic Cell Death
2015
Apoptosis Following Photodynamic Tumor Therapy: Induction, Mechanisms and Detection
2005
Heme oxygenase-1 protects tumor cells against photodynamic therapy-mediated cytotoxicity
2006
Hypericin-loaded nanoparticles for the photodynamic treatment of ovarian cancer
2006
Intracellular target for photosensitization in cancer antiangiogenic photodynamic therapy mediated by polycation liposome
2004
Bioluminescence resonance energy transfer using luciferase-immobilized quantum dots for self-illuminated photodynamic therapy
2012
Can nanotechnology potentiate photodynamic therapy?
2012
The c-Jun N-terminal protein kinase family of mitogen-activated protein kinases (JNK MAPKs)
2001
Nanodrug applications in photodynamic therapy
2010
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Distinct transduction mechanisms of cyclooxygenase 2 gene activation in tumour cells after photodynamic therapy
2005
Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells
2018
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
Photoexpulsion of Surface-Grafted Ruthenium Complexes and Subsequent Release of Cytotoxic Cargos to Cancer Cells from Mesoporous Silica Nanoparticles
2013 StandoutNobel
High hydrostatic pressure induces immunogenic cell death in human tumor cells
2014
Hypocrellin-Loaded Gold Nanocages with High Two-Photon Efficiency for Photothermal/Photodynamic Cancer Therapy in Vitro
2012
Phosphorylation of the hepatitis C virus NS5A protein in vitro and in vivo: properties of the NS5A-associated kinase
1997 StandoutNobel
Endoplasmic Reticulum Stress in Immunity
2014
Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells
2008
Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications
2008 Standout
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Photodynamic Therapy (PDT): PDT Mechanisms
2013
Recent Developments in Isocyanide Based Multicomponent Reactions in Applied Chemistry
2005 Standout
Innate Immune Recognition of Cancer
2015
Nanoparticles in Photodynamic Therapy
2015 Standout
Efficient Initiation of HCV RNA Replication in Cell Culture
2000 StandoutScienceNobel
Ethanol-Induced Apoptotic Neurodegeneration and Fetal Alcohol Syndrome
2000 StandoutScience
The eye lens has an active ubiquitin-protein conjugation system.
1986 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Calreticulin Expression in Human Non–Small Cell Lung Cancers Correlates with Increased Accumulation of Antitumor Immune Cells and Favorable Prognosis
2016
Drug Delivery Systems: Entering the Mainstream
2004 StandoutScience
A Chinese hamster cell cycle mutant arrested at G2 phase has a temperature-sensitive ubiquitin-activating enzyme, E1.
1988 StandoutNobel
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation
2019
An overview on preclinical and clinical experiences with photodynamic therapy for bladder cancer.
2011
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
New photosensitizers for photodynamic therapy
2016 Standout
The Protein Kinase C Agonist PEP005 (Ingenol 3-Angelate) in the Treatment of Human Cancer: A Balance between Efficacy and Toxicity
2010
Tumor necrosis factor stimulates multiple serine/threonine protein kinases in Swiss 3T3 and L929 cells. Implication of casein kinase-2 and extracellular signal-regulated kinases in the tumor necrosis factor signal transduction pathway.
1992
Identification of the Major Phosphorylation Site of the Hepatitis C Virus H Strain NS5A Protein as Serine 2321
1999 StandoutNobel
Photodynamic Therapy with Fullerenes In Vivo : Reality or a Dream?
2011
Emerging Targets in Photopharmacology
2016 StandoutNobel
Reversible Photochemical Control of Singlet Oxygen Generation Using Diarylethene Photochromic Switches
2014 StandoutNobel
Cell Death Pathways in Photodynamic Therapy of Cancer
2011
Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)
2014 Standout
Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease
2010
Dye Sensitizers for Photodynamic Therapy
2013
Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85
1984 StandoutNobel
Ubiquitin-mediated protein degradation.
1988 StandoutNobel
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Celecoxib and NS-398 Enhance Photodynamic Therapy by Increasing In vitro Apoptosis and Decreasing In vivo Inflammatory and Angiogenic Factors
2005
Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing
2013
Photodynamic Therapy in Oncology
2006
Metabolism of ubiquitinated histones.
1981 StandoutNobel
Immunogenic Cell Death in Cancer Therapy
2012 Standout

Works of Peter de Witte being referenced

Photodynamic treatment of basal cell carcinoma and squamous cell carcinoma with hypericin.
1999
A comparative study of the photosensitizing characteristics of some cyanine dyes
2000
Transferrin-Conjugated Liposome Targeting of Photosensitizer AlPcS4 to Rat Bladder Carcinoma Cells
2004
Hypericin in cancer treatment: more light on the way
2002
Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells
2007
Up-regulation of Cyclooxygenase-2 and Apoptosis Resistance by p38 MAPK in Hypericin-mediated Photodynamic Therapy of Human Cancer Cells
2003
The Activation of the c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase Signaling Pathways Protects HeLa Cells from Apoptosis Following Photodynamic Therapy with Hypericin
1999
Apoptotic and anti-apoptotic signaling pathways induced by photodynamic therapy with hypericin
2000
A robust human norovirus replication model in zebrafish larvae
2019
ETHANOL INDUCES HIGHER BEC IN CB1 CANNABINOID RECEPTOR KNOCKOUT MICE WHILE DECREASING ETHANOL PREFERENCE
2004
Induction of heme-oxygenase 1 requires the p38MAPK and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy
2007
Differential cytotoxic effects induced after photosensitization by hypericin
1997
Photosensitized inhibition of growth factor-regulated protein kinases by hypericin
1995
Targeted inhibition of p38α MAPK suppresses tumor-associated endothelial cell migration in response to hypericin-based photodynamic therapy
2005
In vitro transport and uptake of protohypericin and hypericin in the Caco-2 model
1999
Biodistribution of PVP-hypericin and hexaminolevulinate-induced PpIX in normal and orthotopic tumor-bearing rat urinary bladder
2010
Photodynamic therapy with hypericin induces vascular damage and apoptosis in the RIF‐1 mouse tumor model
2001
Evaluation of tumor affinity of mono‐[123I]iodohypericin and mono‐[123I]iodoprotohypericin in a mouse model with a RIF‐1 tumor
2007
Biodistribution of hypericin in orthotopic transitional cell carcinoma bladder tumors: Implication for whole bladder wall photodynamic therapy
2001
Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage
2010
Synergistic effect of photodynamic therapy with hypericin in combination with hyperthermia on loss of clonogenicity of RIF-1 cells
2001
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
2012
Efficacy of antitumoral photodynamic therapy with hypericin: Relationship between biodistribution and photodynamic effects in the RIF-1 mouse tumor model
2001
Enhancing the antitumoral effect of hypericin‐mediated photodynamic therapy by hyperthermia
2002
Inhibition of epidermal growth factor receptor tyrosine kinase activity by hypericin
1993
Photocytotoxic effect of pseudohypericin versus hypericin
1998
Photodynamic therapy efficacy and tissue distribution of hypericin in a mouse P388 lymphoma tumor model
2000
Stability of different formulations and ion pairs of hypericin
2005
Hypericin‐induced photosensitization of HeLa cells leads to apoptosis or necrosis
1998
Phosphorylation of Bcl-2 in G2/M Phase-arrested Cells following Photodynamic Therapy with Hypericin Involves a CDK1-mediated Signal and Delays the Onset of Apoptosis
2002
Hypericin as a Marker for Determination of Tissue Viability After Intratumoral Ethanol Injection in a Murine Liver Tumor Model
2007
Radioiodinated Hypericin: Its Biodistribution, Necrosis Avidity and Therapeutic Efficacy are Influenced by Formulation
2013
A safety study on single intravenous dose of tetrachloro-diphenyl glycoluril [iodogen] dissolved in dimethyl sulphoxide (DMSO)
2013
Photocytotoxicity of hypericin in normoxic and hypoxic conditions
2000
Proceedings of the First International Conference on PEP005
2007
Hypericin‐based fluorescence diagnosis of bladder carcinoma
2002
Targeting of the photocytotoxic compound AlPcS4 to hela cells by transferrin conjugated peg‐liposomes
2002
First preclinical evaluation of mono-[123I]iodohypericin as a necrosis-avid tracer agent
2006
Effect of vehicles and esterification on the penetration and distribution of hypericin in the skin of hairless mice
2007
Sequential Systemic Administrations of Combretastatin A4 Phosphate and Radioiodinated Hypericin Exert Synergistic Targeted Theranostic Effects with Prolonged Survival on SCID Mice Carrying Bifocal Tumor Xenografts
2013
Hypericin as a potential phototherapeutic agent in superficial transitional cell carcinoma of the bladder
2004
The Multifaceted Photocytotoxic Profile of Hypericin
2009
Different Pathways Mediate Cytochrome c Release After Photodynamic Therapy with Hypericin
2001
Epidermal growth factor-mediated targeting of chlorin e6 selectively potentiates its photodynamic activity.
2000
Photocytotoxic action of EGF-PVA-Sn(IV)chlorin e6 and EGF-dextran-Sn(IV)chlorin e6 internalizable conjugates on A431 cells.
1998
Transferrin-mediated targeting of hypericin embedded in sterically stabilized PEG-liposomes
2002
In vivo photodynamic activity of hypericin in transitional cell carcinoma bladder tumors
2001
Rapid stimulation of Ser/Thr protein kinases following treatment of Swiss 3T3 cells with bombesin. Involvement of casein kinase-2 in the signaling pathway of bombesin.
1992
Cellular Photodestruction Induced by Hypericin in AY-27 Rat Bladder Carcinoma Cells
2001
Antivascular Tumor Eradication by Hypericin-mediated Photodynamic Therapy¶
2002
Resistance to anticancer vaccination effect is controlled by a cancer cell-autonomous phenotype that disrupts immunogenic phagocytic removal
2015
Liquid‐phase synthesis of mixture‐based bicyclic β‐lactam libraries
2003
Cytotoxicity and Antiproliferative Effect of Hypericin and Derivatives after Photosensitization
1998
Confluence dependent resistance to photo-activated hypericin in HeLa cells.
1999
Photodynamic activity of hypericin in human urinary bladder carcinoma cells.
2000
The impact of aggregation on the biodistribution of hypericin
2006
Naloxone Reduces Alcohol Intake in a Free-Choice Procedure Even when Both Drinking Bottles Contain Saccharin Sodium or Quinine Substances
1984
Photodynamic therapy with hypericin in a mouse P388 tumor model: vascular effects determine the efficacy
2001
FLUORESCENCE DETECTION OF FLAT BLADDER CARCINOMA IN SITU AFTER INTRAVESICAL INSTILLATION OF HYPERICIN
2000
PERMEATION OF HYPERICIN IN SPHEROIDS COMPOSED OF DIFFERENT GRADE TRANSITIONAL CELL CARCINOMA CELL LINES AND NORMAL HUMAN UROTHELIAL CELLS
2005
Tanshinone IIA Exhibits Anticonvulsant Activity in Zebrafish and Mouse Seizure Models
2013
Potentiation of Photodynamic Therapy with Hypericin by Mitomycin C in the Radiation-induced Fibrosarcoma-1 Mouse Tumor Model ¶
2003
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