Citation Impact
Citing Papers
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
2013 StandoutScience
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Small-Molecule Inhibitors of Phosphatidylinositol 3-Kinase/Akt Signaling Inhibit Wnt/β-Catenin Pathway Cross-Talk and Suppress Medulloblastoma Growth
2009
TOR Signaling in Growth and Metabolism
2006 Standout
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Oxygen Levels in Normal and Previously Irradiated Human Skin as Assessed by EF5 Binding
2006
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation
1999 StandoutNatureNobel
The WHO Classification of Tumors of the Nervous System
2002 Standout
Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer
2013 Standout
Integrins in cancer: biological implications and therapeutic opportunities
2009 Standout
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Advances in Radiation Therapy for Brain Tumors
2007
Cancer Metastasis: Building a Framework
2006 Standout
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
FASTKD2 Nonsense Mutation in an Infantile Mitochondrial Encephalomyopathy Associated with Cytochrome C Oxidase Deficiency
2008
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Potentiation of neuroblastoma metastasis by loss of caspase-8
2006 Nature
The Hedgehog's tale: developing strategies for targeting cancer
2011
Mitochondrial Encephalopathy, Lactic Acidosis, and Strokelike Episodes
2008
Facets and determinants of quality of life in patients with recurrent high grade glioma
2005
Clk post-transcriptional control denoises circadian transcription both temporally and spatially
2015 StandoutNobel
High incidence of secondary brain tumours after radiotherapy and antimetabolites
1999
Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors
2005 Standout
Mathematical Model of the Drosophila Circadian Clock: Loop Regulation and Transcriptional Integration
2009
Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell Carcinoma
2007 Standout
Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma
2014 Standout
Insulin-like Growth Factor 1 Induces Hypoxia-inducible Factor 1-mediated Vascular Endothelial Growth Factor Expression, Which is Dependent on MAP Kinase and Phosphatidylinositol 3-Kinase Signaling in Colon Cancer Cells
2002 StandoutNobel
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
Death Receptor Recruitment of Endogenous Caspase-10 and Apoptosis Initiation in the Absence of Caspase-8
2001
Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme
2005
Integrins as “functional hubs” in the regulation of pathological angiogenesis
2009
Advances in the treatment of neurofibromatosis-associated tumours
2013
Gene directed enzyme/prodrug therapy of cancer: Historical appraisal and future prospectives
2001
Neural Stem Cells and the Origin of Gliomas
2005
Hypoxia in cancer: significance and impact on clinical outcome
2007 Standout
Variable Retinal and Neurologic Manifestations in Patients Harboring the Mitochondrial DNA 8993 Mutation
1993
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Malignant Gliomas in Adults
2008 Standout
Clinical features of melas and mitochondrial DNA mutations
1995
Axonal Transection in the Lesions of Multiple Sclerosis
1998 Standout
Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
2012 Standout
Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model
2004
Glioma Stem Cells: A Midterm Exam
2008
Sibling rivalry in the E2F family
2002
Radiation Dose–Volume Effects in the Heart
2010
Rho and Rac Take Center Stage
2004 Standout
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
A mutation in the tRNALeu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies
1990 StandoutNature
Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes
2003 Standout
Systemic vascular smooth muscle cell impairment in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
1995
Signal Pathways Involved in Activation of p70S6K and Phosphorylation of 4E-BP1 following Exposure of Multiple Myeloma Tumor Cells to Interleukin-6
2002
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
mTOR-targeted therapy of cancer with rapamycin derivatives
2005
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido
2011 StandoutNobel
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Identification of human brain tumour initiating cells
2004 StandoutNature
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
2009 Standout
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy maps to chromosome 19q12
1993
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Reversible decreases in N‐acetylaspartate after acute brain injury
1995
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
2007 StandoutNature
Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia
1996 StandoutNature
Inhibition of IGF-I receptor in anchorage-independence attenuates GSK-3β constitutive phosphorylation and compromises growth and survival of medulloblastoma cell lines
2006
TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin
2011 StandoutNobel
Detection and Characterization of Tumor Hypoxia Using pO 2 Histography
2007
Human Bone Marrow–Derived Mesenchymal Stem Cells in the Treatment of Gliomas
2005
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Autosomal dominant syndrome with strokelike episodes and leukoencephalopathy.
1991
Biology of the p21-Activated Kinases
2003
Retroviral transfer of human cytochrome P450 genes for oxazaphosphorine-based cancer gene therapy.
1998
Phase II Study of Imatinib in Patients With Recurrent Gliomas of Various Histologies: A European Organisation for Research and Treatment of Cancer Brain Tumor Group Study
2008
The Organocatalytic Approach to Enantiopure 2H‐ and 3H‐Pyrroles: Inhibitors of the Hedgehog Signaling Pathway
2016 StandoutNobel
Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence
2003 Standout
Biology of Gastrointestinal Stromal Tumors
2004 Standout
Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation.
2001
Apoptosis Associated with Deregulated E2F Activity Is Dependent on E2F1 and Atm/Nbs1/Chk2
2004
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
A randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt) to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors.
1999
Mitochondrial Diseases in Man and Mouse
1999 StandoutScience
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Drug Delivery Systems: Entering the Mainstream
2004 StandoutScience
Phase III Randomized, Intergroup Trial Assessing Imatinib Mesylate At Two Dose Levels in Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing the Kit Receptor Tyrosine Kinase: S0033
2008
Safety and Pharmacokinetics of Escalated Doses of Weekly Intravenous Infusion of CCI-779, a Novel mTOR Inhibitor, in Patients With Cancer
2004
Inhibitors of the mammalian target of rapamycin
2005
Handicapping the Race to Develop Inhibitors of the Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin Pathway
2006
Autosomal dominant leukoencephalopathy and subcortical ischemic stroke. A clinicopathological study.
1993
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
The type I insulin-like growth factor receptor pathway: a key player in cancer therapeutic resistance
2008
Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics
1999 StandoutScience
Cancerous stem cells can arise from pediatric brain tumors
2003 Standout
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
A Phase I and Pharmacokinetic Study of Temsirolimus (CCI-779) Administered Intravenously Daily for 5 Days Every 2 Weeks to Patients with Advanced Cancer
2006
Works of Peter C. Phillips∥ being referenced
Phase I trial of imatinib in children with newly diagnosed brainstem and recurrent malignant gliomas: A Pediatric Brain Tumor Consortium report1
2007
Treatment of children with newly diagnosed brain stem gliomas with intravenous recombinant β-interferon and hyperfractionated radiation therapy: A Childrens Cancer Group phase I/II study
1996
Surgery with or without radiation therapy in the management of craniopharyngiomas in children and young adults
2004
p53 gene mutations in pediatric brain tumors
1995
Loss of caspase-8 mRNA expression is common in childhood primitive neuroectodermal brain tumour/medulloblastoma
2002
Acute neurotoxicity after intrathecal cytosine arabinoside in two adolescents with acute lymphoblastic leukemia of B-cell type
1993
Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression
2000
Carboplatin and vincristine chemotherapy for children with newly diagnosed progressive low-grade gliomas
1997
Outcome for children with supratentorial primitive neuroectodermal tumors treated with surgery, radiation, and chemotherapy
2000
Brainstem tumors in patients with neurofibromatosis type 1
1995
Treatment of Advanced CNS Malignancies with the Recombinant Adenovirus H5.010RSVTK: A Phase I Trial. University of Pennsylvania Medical Center, Philadelphia
1996
Treatment of Recurrent or Progressive Malignant Glioma with a Recombinant Adenovirus Expressing Human Interferon-Beta (H5.010CMV hIFN -β): A Phase I Trial
2001
Phase I Clinical Trial of Cilengitide in Children With Refractory Brain Tumors: Pediatric Brain Tumor Consortium Study PBTC-012
2008
Late cognitive and radiographic changes related to radiotherapy
2002
Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes: A distinctive clinical syndrome
1984
Autocrine secreted insulin-like growth factor-I stimulates MAP kinase-dependent mitogenic effects in human primitive neuroectodermal tumor/medulloblastoma.
2000
A phase I pharmacokinetic trial of sonic hedgehog (SHH) antagonist GDC-0449 in pediatric patients with recurrent or refractory medulloblastoma: A Pediatric Brain Tumor Consortium study (PBTC 25).
2010
A role for Pak protein kinases in Schwann cell transformation
1998
Antisense treatment of IGF-IR induces apoptosis and enhances chemosensitivity in central nervous system atypical teratoid/rhabdoid tumours cells
2007
Antitumor activity of the rapamycin analog CCI-779 in human primitive neuroectodermal tumor/medulloblastoma models as single agent and in combination chemotherapy.
2001
p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin.
1999
Comparative Measurements of Hypoxia in Human Brain Tumors Using Needle Electrodes and EF5 Binding
2004
Midline Supratentorial Tumors
1992
Loss of caspase-8 protein expression correlates with unfavorable survival outcome in childhood medulloblastoma.
2003