Citation Impact
Citing Papers
Molecular analysis of complex human cell populations: mutational spectra of MNNG and ICR-191
1990
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
1992 StandoutNobel
When Checkpoints Fail
1997 StandoutNobel
Degradation of 3-Hydroxy-3-methylglutaryl-CoA Reductase in Endoplasmic Reticulum Membranes Is Accelerated as a Result of Increased Susceptibility to Proteolysis
1996 StandoutNobel
Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome
1995 StandoutNobel
Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair
1993 StandoutNobel
Where transcription meets repair
1994 StandoutNobel
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
1992
soluble form of CD4 (T4) protein inhibits AIDS virus infection
1988 StandoutNatureNobel
Amplified DNA sequences in Y1 mouse adrenal tumor cells: association with double minutes and localization to a homogeneously staining chromosomal region.
1982
Induction of Gene Amplification by Arsenic
1988 Science
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.
1993 StandoutNobel
Transient involvement of signal recognition particle and its receptor in the microsomal membrane prior to protein translocation
1983 StandoutNobel
Single-Copy and Amplified CAD Genes in Syrian Hamster Chromosomes Localized by a Highly Sensitive Method for In Situ Hybridization
1982
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neuOncogene
1987 StandoutScience
Carcinogen-mediated methotrexate resistance and dihydrofolate reductase amplification in Chinese hamster cells.
1986
A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration.
1991
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
2000 StandoutNobel
Structure of amplified normal and variant dihydrofolate reductase genes in mouse sarcoma S180 cells.
1982
The organization and amplification of two chromosomal domains containing drosophila chorion genes
1981
THE MOLECULAR GENETICS OF CELLULAR ONCOGENES
1984
Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage
1984 StandoutScienceNobel
Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA
1983 StandoutNobel
Isolation of the proto-oncogene c-myb from D. melanogaster
1985 StandoutNobel
Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma.
1984 StandoutNobel
Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus.
1989
A structure for amplified DNA
1983 StandoutNobel
Gene amplification and gene correction in somatic cells
1982 StandoutNobel
Activation of the c-myc gene by translocation: a model for translational control.
1983 StandoutNobel
Nucleotide sequence of the human N-myc gene.
1986 StandoutNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes
1981 StandoutNobel
Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences.
1983
Size heterogeneity in the 3′ end of dihydrofolate reductase messenger RNAs in mouse cells
1980
Transposition and amplification of oncogene-related sequences in human neuroblastomas
1983
Phorbol ester dramatically increases incidence of methotrexate-resistant mouse cells: Possible mechanisms and relevance to tumor promotion
1981
A subset of herpes simplex virus replication genes induces DNA amplification within the host cell genome
1989 StandoutNobel
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells
1983 StandoutNatureNobel
A novel ras-related gene family
1985 StandoutNobel
Identification of nuclear proteins encoded by viral and cellular myc oncogenes
1983 StandoutNatureNobel
Molecular cloning of 3-hydroxy-3-methylglutaryl coenzyme a reductase and evidence for regulation of its mRNA.
1982 StandoutNobel
Double minutes in human tumor cells
1982
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour
1983 StandoutNatureNobel
Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc
1984 StandoutNatureNobel
Cyclic AMP regulation of lactate dehydrogenase. Isoproterenol and N6,O2-dibutyryl cyclic amp increase the rate of transcription and change the stability of lactate dehydrogenase a subunit messenger RNA in rat C6 glioma cells.
1983
Unstable amplification of an altered dihydrofolate reductase gene associated with double-minute chromosomes
1981
Regulated expression of human growth hormone genes in mouse cells
1982 StandoutNobel
Transcription factor Sp1 recognizes a DNA sequence in the mouse dihydrofolate reductase promoter
1986 Nature
Amplification and enhanced expression of the c-myc oncogene in mouse SEWA tumour cells
1985 StandoutNatureNobel
In vitro translation of hypoxanthine/guanine phosphoribosyltransferase mRNA: characterization of a mouse neuroblastoma cell line that has elevated levels of hypoxanthine/guanine phosphoribosyltransferase protein.
1981
Murine dihydrofolate reductase transcripts through the cell cycle.
1986
Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma.
1984 StandoutNobel
Blastoderm-differential and blastoderm-specific genes of Drosophila melanogaster
1985
Methotrexate resistance and gene amplification. Mechanisms and implications
1986
DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall
1985
A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA
1985 StandoutNobel
Activation of a translocated c-myc gene: role of structural alterations in the upstream region.
1984 StandoutNobel
Gene amplification in cultured animal cells
1984
cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure.
1989 StandoutNobel
Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin.
1984
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.
1983 StandoutNobel
A Drosophila Minute gene encodes a ribosomal protein
1985 StandoutNatureNobel
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Herpes simplex virus virion host shutoff function
1988
Gene amplification in cultured cells.
1988
Increased rate of base substitution in a hamster mutator strain obtained during serial selection for gene amplification.
1990
A cellular gene encodes scrapie PrP 27-30 protein
1985 StandoutNobel
Gene amplification in a leukemic patient treated with methotrexate.
1984
Cytologic evidence for gene amplification in methotrexate-resistant cells obtained from a patient with ovarian adenocarcinoma.
1984
Phospholipid is required for the processing of presecretory proteins by detergent-solubilized canine pancreatic signal peptidase.
1981
Cloning of DNA from double minutes of Y1 mouse adrenocortical tumor cells: Evidence for gene amplification
1981
The adeno-associated virus rep gene suppresses herpes simplex virus-induced DNA amplification
1990 StandoutNobel
Oncogene Amplification in Tumor Cells
1986
DNA amplification of adeno-associated virus as a response to cellular genotoxic stress.
1988
Single-copy and amplified CAD genes in Syrian hamster chromosomes localized by a highly sensitive method for in situ hybridization.
1982
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
1986 StandoutNobel
Murine Dihydrofolate Reductase Transcripts Through the Cell Cycle
1986
Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells.
1993
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Expression of N-myc in teratocarcinoma stem cells and mouse embryos
1985 StandoutNatureNobel
Unstable Methotrexate Resistance in Human Small-Cell Carcinoma Associated with Double Minute Chromosomes
1983
Targeted mutation of the Hprt gene in mouse embryonic stem cells.
1988 StandoutNobel
The protein encoded by the human proto-oncogene c-myc.
1984 StandoutNobel
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSα/hMutSβ ratio and reduces the efficiency of base–base mismatch repair
1997 StandoutNobel
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture
1985 StandoutNatureNobel
Cockayne syndrome group B protein enhances elongation by RNA polymerase II
1997 StandoutNobel
Works of Peter C. Brown being referenced
Coordinated modulation of albumin synthesis and mRNA levels in cultured hepatoma cells by hydrocortisone and cyclic AMP analogs.
1979
Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea.
1983
UV Radiation Facilitates Methotrexate Resistance and Amplification of the Dihydrofolate Reductase Gene in Cultured 3T6 Mouse Cells
1984
Relationship of Amplified Dihydrofolate Reductase Genes to Double Minute Chromosomes in Unstably Resistant Mouse Fibroblast Cell Lines
1981
UV radiation facilitates methotrexate resistance and amplification of the dihydrofolate reductase gene in cultured 3T6 mouse cells.
1984
Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea
1983
Mouse albumin mRNA in liver and a hepatoma cell line
1979
Chromosomal and Extrachromosomal Localization of Amplified Dihydrofolate Reductase Genes in Cultured Mammalian Cells
1981
Relationship of amplified dihydrofolate reductase genes to double minute chromosomes in unstably resistant mouse fibroblast cell lines.
1981
Mouse albumin mRNA in liver and a hepatoma cell line. Preparation of complementary DNA from purified mRNA and quantitation by nucleic acid hybridization.
1979
Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes.
1979
Mechanisms of 3-hydroxy-3-methylglutaryl coenzyme A reductase overaccumulation in three compactin-resistant cell lines.
1985
Loss and stabilization of amplified dihydrofolate reductase genes in mouse sarcoma S-180 cell lines.
1981