Standout Papers
Citation Impact
Citing Papers
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
2008 Standout
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
EglN2 associates with the NRF 1‐ PGC 1α complex and controls mitochondrial function in breast cancer
2015 StandoutNobel
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR
2014
Hallmarks of Cancer: The Next Generation
2011 Standout
Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice
2010
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Hypoxia-regulated target genes implicated in tumor metastasis
2012
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
Why do cancers have high aerobic glycolysis?
2004 Standout
Bone marrow-derived mesenchymal stem cells and the tumor microenvironment
2010
EGFR Antagonists in Cancer Treatment
2008 Standout
Molecular networks implicated in speech-related disorders: FOXP2 regulates the SRPX2/uPAR complex
2010
HIF-1α, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
2005 StandoutNobel
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
2008 StandoutNature
Hepatocellular carcinoma
2018 Standout
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Targeting hypoxia cell signaling for cancer therapy
2007
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c
2016 StandoutNobel
EMT and Dissemination Precede Pancreatic Tumor Formation
2012 Standout
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
Involvement of endothelial progenitor cells in tumor vascularization
2010
Focused 2012 Update of the Canadian Cardiovascular Society Atrial Fibrillation Guidelines: Recommendations for Stroke Prevention and Rate/Rhythm Control
2012
Survival and apoptosis: a dysregulated balance in liver cancer
2007
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
2006 StandoutNobel
Scleroderma
2009 Standout
Prolyl Hydroxylase PHD3 Enhances the Hypoxic Survival and G1 to S Transition of Carcinoma Cells
2011
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Expression of Snail in Pancreatic Cancer Promotes Metastasis and Chemoresistance
2007
Regulation of Hypoxia-Inducible Factor-1α, Vascular Endothelial Growth Factor, and Angiogenesis by an Insulin-Like Growth Factor-I Receptor Autocrine Loop in Human Pancreatic Cancer
2003 StandoutNobel
Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1
2012 StandoutNobel
Molecular prognostic markers in pancreatic cancer: A systematic review
2005
The semaphorins: versatile regulators of tumour progression and tumour angiogenesis
2008
Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids
2011
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Analysis and Separation of Residues Important for the Chemoattractant and Antimicrobial Activities of β-Defensin 3
2008 StandoutNobel
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
2013 StandoutNobel
Functional significance of vascular endothelial growth factor receptors on gastrointestinal cancer cells
2007
Elusive Identities and Overlapping Phenotypes of Proangiogenic Myeloid Cells in Tumors
2010
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α
2009 StandoutNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Hypoxia-inducible Factor-1 Deficiency Results in Dysregulated Erythropoiesis Signaling and Iron Homeostasis in Mouse Development
2006 StandoutNobel
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Hypoxia Promotes Tumor Growth in Linking Angiogenesis to Immune Escape
2012
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Vascular endothelial growth factor receptor‐1 promotes migration and invasion in pancreatic carcinoma cell lines
2005
Angiogenesis as a therapeutic target
2005 StandoutNature
Tumor Angiogenesis
2008 Standout
Liver transplantation for hepatocellular carcinoma: outcomes and novel surgical approaches
2017
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
Autocrine Motility Factor Signaling Enhances Pancreatic Cancer Metastasis
2004
TGF‐β signaling and the fibrotic response
2004 Standout
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Secretome Analysis of Multiple Pancreatic Cancer Cell Lines Reveals Perturbations of Key Functional Networks
2010
FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
2011 Standout
Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice
2008
Selective Killing of Hypoxia-Inducible Factor-1–Active Cells Improves Survival in a Mouse Model of Invasive and Metastatic Pancreatic Cancer
2009 StandoutNobel
Akt Stimulates Aerobic Glycolysis in Cancer Cells
2004
Genes and pathways downstream of telomerase in melanoma metastasis
2006 StandoutNobel
Human β‐defensin 4: a novel inducible peptide with a specific salt‐sensitive spectrum of antimicrobial activity
2001
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin
2020
Role of Hypoxia-Inducible Factors in Breast Cancer Metastasis
2013 StandoutNobel
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
PHD3-mediated prolyl hydroxylation of nonmuscle actin impairs polymerization and cell motility
2014 StandoutNobel
IFN-α–Induced Apoptosis in Hepatocellular Carcinoma Involves Promyelocytic Leukemia Protein and TRAIL Independently of p53
2009
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation
2014 Standout
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Distinct breast cancer stem/progenitor cell populations require either HIF1α or loss of PHD3 to expand under hypoxic conditions
2015
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Metastatic pancreatic cancer: Is gemcitabine still the best standard treatment? (Review)
2010
Works of Peter Büchler being referenced
Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt
2004
Primary human hepatocytes – a valuable tool for investigation of apoptosis and hepatitis B virus infection
2003
PHD3 regulates differentiation, tumour growth and angiogenesis in pancreatic cancer
2010
VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma
2008
Therapy for pancreatic cancer with a recombinant humanized anti-HER2 antibody (herceptin)
2001
Real-Time Quantitative PCR of Telomerase mRNA Is Useful for the Differentiation of Benign and Malignant Pancreatic Disorders
2001
Connective Tissue Growth Factor is Involved in Pancreatic Repair and Tissue Remodeling in Human and Rat Acute Necrotizing Pancreatitis
2002
Transcriptional Regulation of Urokinase-type Plasminogen Activator Receptor by Hypoxia-Inducible Factor 1 Is Crucial for Invasion of Pancreatic and Liver Cancer
2009
Invasion and metastasis in pancreatic cancer.
2003
Patients With Non–[18F]Fludeoxyglucose-Avid Advanced Hepatocellular Carcinoma on Clinical Staging May Achieve Long-Term Recurrence-Free Survival After Liver Transplantation
2011
Structural and functional analysis of the BMP-4 promoter in early embryos of Xenopus laevis
1998
Antiangiogenic activity of genistein in pancreatic carcinoma cells is mediated by the inhibition of hypoxia‐inducible factor‐1 and the down‐regulation of VEGF gene expression
2003
Association of axon guidance factor Semaphorin 3A with poor outcome in pancreatic cancer
2007
Origin and Development of the Precursor Lesions in Experimental Pancreatic Cancer in Rats
2003
Hypoxia-Inducible Factor 1 Regulates Vascular Endothelial Growth Factor Expression in Human Pancreatic Cancer
2003 StandoutNobel
Acute Liver Failure Associated With Dronedarone
2011
VEGF-RII Influences the Prognosis of Pancreatic Cancer
2002