Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Differential Antigen Processing by Dendritic Cell Subsets in Vivo
2007 StandoutScienceNobel
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
Chloroquine enhances human CD8 + T cell responses against soluble antigens in vivo
2005
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
FLT3 Ligand Enhances the Cancer Therapeutic Potency of Naked RNA Vaccines
2011
Autophagy promotes MHC class II presentation of peptides from intracellular source proteins
2005
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Recognition of a Ubiquitous Self Antigen by Prostate Cancer-Infiltrating CD8 + T Lymphocytes
2008 StandoutScienceNobel
Long-Lasting Complete Responses in Patients with Metastatic Melanoma after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes and an Attenuated IL2 Regimen
2016
Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells
2005 StandoutNobel
Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
2019 StandoutScienceNobel
The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
2009 StandoutNobel
Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose
2016
Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action
2019 StandoutNobel
Nucleoside-modified mRNA vaccination partially overcomes maternal antibody inhibition of de novo immune responses in mice
2020 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Mucins in cancer: function, prognosis and therapy
2009
Self-adjuvanted mRNA vaccination in advanced prostate cancer patients: a first-in-man phase I/IIa study
2015
Coronaviren als Ursache respiratorischer Infektionen
2019
mRNA-based dendritic cell vaccines
2014
Autophagy in innate and adaptive immunity
2005
mRNA Cancer Vaccines—Messages that Prevail
2017
Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
2003
Intradermal Electroporation of Naked Replicon RNA Elicits Strong Immune Responses
2012
Antigen-Loading Compartments for Major Histocompatibility Complex Class II Molecules Continuously Receive Input from Autophagosomes
2006
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Complete molecular remissions induced by patient-specific vaccination plus granulocyte–monocyte colony-stimulating factor against lymphoma
1999
Infection of dendritic cells by murine cytomegalovirus induces functional paralysis
2001
DC-based cancer vaccines
2007
Autophagy and antiviral immunity
2008
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Analysis of the T cell response to tumor and viral peptide antigens by an IFNγ-ELISPOT assay
1997
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Host tissue determinants of tumour immunity
2019
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Active immunization against cancer with dendritic cells: The near future
2001 StandoutNobel
Dendritic cells transfected with interleukin-12 and tumor-associated antigen messenger RNA induce high avidity cytotoxic T cells
2006
Mucin-1 is expressed on dendritic cells, both in vitro and in vivo
2004
Enhancement of T‐cell‐mediated anti‐tumour immunity via the ectopically expressed glucocorticoid‐induced tumour necrosis factor receptor‐related receptor ligand (GITRL) on tumours
2008 StandoutNobel
Yeasts encoding tumour antigens in cancer immunotherapy
2005
Regulatory T Cells
2000 StandoutNobel
Results of the First Phase I/II Clinical Vaccination Trial With Direct Injection of mRNA
2008
Uptake of synthetic naked RNA by skin-resident dendritic cells via macropinocytosis allows antigen expression and induction of T-cell responses in mice
2016
Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin
2012 StandoutNobel
RNA: The new revolution in nucleic acid vaccines
2013
The Human T Cell Response to Melanoma Antigens
2006
Autophagy in innate and adaptive immunity against intracellular pathogens
2006
Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals
2015
Simultaneous ex vivo quantification of antigen-specific CD4+ and CD8+ T cell responses using in vitro transcribed RNA
2007
Tumor vaccination using messenger RNA: prospects of a future therapy
2011
Effective induction of anti-melanoma immunity following genetic vaccination with synthetic mRNA coding for the fusion protein EGFP.TRP2
2005
mRNA
2013
Human Cytomegalovirus Binding to DC-SIGN Is Required for Dendritic Cell Infection and Target Cell trans-Infection
2002
Unveiling the roles of autophagy in innate and adaptive immunity
2007
Autophagy in Innate Immunity against Intracellular Bacteria
2006
Type I IFN Counteracts the Induction of Antigen-Specific Immune Responses by Lipid-Based Delivery of mRNA Vaccines
2012
Optimized dendritic cell-based immunotherapy for melanoma: the TriMix-formula
2014
Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma
2009
Innate and Adaptive Immunity through Autophagy
2007
Dendritic cells and tumor immunity
2001
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells
2016
Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems
2017
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Genetically programmed chiral organoborane synthesis
2017 StandoutNatureNobel
Phase I/II trial of a dendritic cell vaccine transfected with DNA encoding melan A and gp100 for patients with metastatic melanoma
2011
The ReNAissanCe of mRNA-based cancer therapy
2014
Mechanisms of Exogenous Antigen Presentation by MHC Class I Molecules in Vitro and in Vivo: Implications for Generating CD8+ T Cell Responses to Infectious Agents, Tumors, Transplants, and Vaccines
1999
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Cancer vaccines: between the idea and the reality
2003
Co‐inhibitory roles for glucocorticoid‐induced TNF receptor in CD1d‐dependent natural killer T cells
2008
Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation
2011
mRNA transcript therapy
2014 StandoutNobel
Autophagy as an immune defense mechanism
2006
Introduction of functional chimeric E/L-selectin by RNA electroporation to target dendritic cells from blood to lymph nodes
2007
Developing mRNA-vaccine technologies
2012
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
Targeting Immunosupportive Cancer Therapies: Accentuate the Positive, Eliminate the Negative
2007 StandoutNobel
Vascular normalization in Rgs5-deficient tumours promotes immune destruction
2008 Nature
The Mechanistic Links Between Proteasome Activity, Aging and Agerelated Diseases
2014
Electroporation-enhanced delivery of nucleic acid vaccines
2014
Lipid-based mRNA vaccine delivery systems
2014
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
2006
Cancer-related inflammation
2008 StandoutNature
Combined immune checkpoint blockade (anti-PD-1/anti-CTLA-4): Evaluation and management of adverse drug reactions
2017
Cancer immunotherapy with mRNA‐transfected dendritic cells
2004
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
RNA-based vaccines
2012
T-cell responses of vaccinated cancer patients
2003
mRNA Cancer Vaccines
2016
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Antitumor Vaccination with Synthetic mRNA: Strategies for In Vitro and In Vivo Preclinical Studies
2012
Dendritic cells as a tool to induce anergic and regulatory T cells
2001
In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells
2010
Boron Chemicals in Diagnosis and Therapeutics
2013
Dendritic Cell Vaccines for Cancer Immunotherapy
1999
Epstein-Barr virus inhibits the development of dendritic cells by promoting apoptosis of their monocyte precursors in the presence of granulocyte macrophage–colony-stimulating factor and interleukin-4
2002
Presentation of Exogenous Antigens on Major Histocompatibility Complex (MHC) Class I and MHC Class II Molecules Is Differentially Regulated during Dendritic Cell Maturation
2003
Differential presentation of the same MHC class I epitopes by fibroblasts and dendritic cells.
1998
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Stimulation of the Glucocorticoid-Induced TNF Receptor Family-Related Receptor on CD8 T Cells Induces Protective and High-Avidity T Cell Responses to Tumor-Specific Antigens
2010 StandoutNobel
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
Differential Presentation of the Same MHC Class I Epitopes by Fibroblasts and Dendritic Cells
1998
Human Tumor Antigens and Cancer Immunotherapy
2015
Nonviral delivery of self-amplifying RNA vaccines
2012
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
MACROPHAGE RECEPTORS AND IMMUNE RECOGNITION
2005
A development that may evolve into a revolution in medicine: mRNA as the basis for novel, nucleotide-based vaccines and drugs
2013
IFN-γ enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation
2004
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Dendritic Cells Genetically Modified with an Adenovirus Vector Encoding the cDNA for a Model Antigen Induce Protective and Therapeutic Antitumor Immunity
1997
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
Induction of Interleukin 10–Producing, Nonproliferating Cd4+ T Cells with Regulatory Properties by Repetitive Stimulation with Allogeneic Immature Human Dendritic Cells
2000
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Cutting Edge: Intravenous Soluble Antigen Is Presented to CD4 T Cells by CD8− Dendritic Cells, but Cross-Presented to CD8 T Cells by CD8+ Dendritic Cells
2001
Induction of Antitumor Immunity with Dendritic Cells Transduced with Adenovirus Vector-Encoding Endogenous Tumor-Associated Antigens
1999
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
RNA-Based Vaccines in Cancer Immunotherapy
2015
Vaccination against Chlamydial Genital Tract Infection after Immunization with Dendritic Cells Pulsed Ex Vivo with Nonviable Chlamydiae
1998
Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy
2016
Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells
2007
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Immunobiology of Dendritic Cells
2000 Standout
HUMAN T CELL RESPONSES AGAINST MELANOMA
2005
Mature Dendritic Cells Infected with Canarypox Virus Elicit Strong Anti-Human Immunodeficiency Virus CD8+and CD4+T-Cell Responses from Chronically Infected Individuals
2001 StandoutNobel
Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells
2006
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Expansion of Melanoma-specific Cytolytic CD8+ T Cell Precursors in Patients with Metastatic Melanoma Vaccinated with CD34+ Progenitor-derived Dendritic Cells
2004
CD8 T Cell-Intrinsic GITR Is Required for T Cell Clonal Expansion and Mouse Survival following Severe Influenza Infection
2010 StandoutNobel
Human cytomegalovirus inhibits maturation and impairs function of monocyte-derived dendritic cells
2002
From the RNA world to the clinic
2016 Science
Autoreactivity, dynamic tuning and selectivity
2001
Cd8+ but Not Cd8− Dendritic Cells Cross-Prime Cytotoxic T Cells in Vivo
2000
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Antibody to Langerin/CD207 localizes large numbers of CD8α + dendritic cells to the marginal zone of mouse spleen
2009 StandoutNobel
Induction of Epstein-Barr Virus-Specific Cytotoxic T-Lymphocyte Responses Using Dendritic Cells Pulsed With EBNA-3A Peptides or UV-Inactivated, Recombinant EBNA-3A Vaccinia Virus
1999 StandoutNobel
Messenger RNA-based vaccines
2004
TNF/TNFR FAMILY MEMBERS IN COSTIMULATION OF T CELL RESPONSES
2004
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Induction of HIV-1 gag specific immune responses by cationic micelles mediated delivery of gag mRNA
2015
Induction of Epstein-Barr Virus-Specific Cytotoxic T-Lymphocyte Responses Using Dendritic Cells Pulsed With EBNA-3A Peptides or UV-Inactivated, Recombinant EBNA-3A Vaccinia Virus
1999 StandoutNobel
Works of Peter Brossart being referenced
Her-2/neu-derived peptides are tumor-associated antigens expressed by human renal cell and colon carcinoma lines and are recognized by in vitro induced specific cytotoxic T lymphocytes.
1998
Intradermal Vaccinations With RNA Coding for TAA Generate CD8+ and CD4+ Immune Responses and Induce Clinical Benefit in Vaccinated Patients
2010
Transfection of Dendritic Cells with RNA Induces CD4- and CD8-Mediated T Cell Immunity Against Breast Carcinomas and Reveals the Immunodominance of Presented T Cell Epitopes
2003
Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells
2000
Proteasome inhibitors: antitumor effects and beyond
2006
Cotransfection of dendritic cells with RNA coding for HER-2/neu and 4-1BBL increases the induction of tumor antigen specific cytotoxic T lymphocytes
2005
Long-term survival correlates with immunological responses in renal cell carcinoma patients treated with mRNA-based immunotherapy
2015
Addition of dacarbazine or cisplatin to interferon-??/interleukin-2 in metastatic melanoma
1995
Restriction of T cell receptor Vβ repertoire in melanoma metastasis responding to immunotherapy
1995
Delivery of tumor-derived RNA for the induction of cytotoxic T-lymphocytes
2003
Transfection of Dendritic Cells with in Vitro-Transcribed CMV RNA Induces Polyclonal CD8+- and CD4+-Mediated CMV-Specific T Cell Responses
2005
Development of Hemolytic Anemia in a Nivolumab-Treated Patient with Refractory Metastatic Squamous Cell Skin Cancer and Chronic Lymphatic Leukemia
2016
A phase I/II study of bortezomib and capecitabine in patients with metastatic breast cancer previously treated with taxanes and/or anthracyclines
2008
Dendritic cells transfected with tumor RNA for the induction of antitumor CTL in colorectal cancer
2003
Survivin is a shared tumor-associated antigen expressed in a broad variety of malignancies and recognized by specific cytotoxic T cells
2003
Effects of Imatinib on Normal Hematopoiesis and Immune Activation
2005
Processing and presentation of HLA class I and II epitopes by dendritic cells after transfection with in vitro–transcribed MUC1 RNA
2004
Immune regulatory loops determine productive interactions within human T lymphocyte–dendritic cell clusters
1999
Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL.
1997
Fatal outcome of human coronavirus NL63 infection despite successful viral elimination by IFN‐alpha in a patient with newly diagnosed ALL
2016
Induction of myeloma-specific cytotoxic T cells using dendritic cells transfected with tumor-derived RNA
2003
Cancer immunoediting by GITR (glucocorticoid‐induced TNF‐related protein) ligand in humans: NK cell/tumor cell interactions
2007
CD63 tetraspanin slows down cell migration and translocates to the endosomal-lysosomal-MIICs route after extracellular stimuli in human immature dendritic cells
2004
Vaccinations with RNA coding for tumor associated antigens in advanced RCC patients—A phase I/II study
2008
Monocyte-derived dendritic cells are permissive to the complete replicative cycle of human cytomegalovirus
2000
Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells
2000
Presentation of exogenous protein antigens on major histocompatibility complex class I molecules by dendritic cells: pathway of presentation and regulation by cytokines.
1997
Induction of chronic lymphocytic leukemia (CLL)–specific CD4- and CD8-mediated T-cell responses using RNA-transfected dendritic cells
2003
Identification of HLA-A2–Restricted T-Cell Epitopes Derived From the MUC1 Tumor Antigen for Broadly Applicable Vaccine Therapies
1999
MHC class I presentation of exogenous protein antigens by dendritic cells
1997
T-cell receptor beta variable region diversity in melanoma metastases after interleukin 2-based immunotherapy.
1996
RNA Vaccines in Cancer Treatment
2010
Presentation of Exogenous Protein Antigens on Major Histocompatability Complex Class I Molecules by Dendritic Cells: Pathway of Presentation and Regulation by Cytokines
1997
Expression of MUC-1 Epitopes on Normal Bone Marrow: Implications for the Detection of Micrometastatic Tumor Cells
1999
Neutralization of tumor-derived soluble Glucocorticoid-Induced TNFR-Related Protein ligand increases NK cell anti-tumor reactivity
2008
Identification and Characterization of T-Cell Epitopes Deduced from RGS5, a Novel Broadly Expressed Tumor Antigen
2007
Tumor necrosis factor alpha and CD40 ligand antagonize the inhibitory effects of interleukin 10 on T-cell stimulatory capacity of dendritic cells.
2000
Presentation of Exogenous Protein Antigens on Major Histocompatability Complex Class I Molecules by Dendritic Cells: Pathway of Presentation and Regulation by Cytokines
1997
The epithelial tumor antigen MUC1 is expressed in hematological malignancies and is recognized by MUC1-specific cytotoxic T-lymphocytes.
2001
Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL.
1997