Citation Impact
Citing Papers
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis
2012 StandoutNobel
Ca2+-dependent regulation in neuronal gene expression
1997
Activation of GABAA receptors containing the α4 subunit by GABA and pentobarbital
2004
Multiple Actions of Propofol on αβγ and αβδ GABAA Receptors
2004
Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes
1998
Presenilins are essential for regulating neurotransmitter release
2009 StandoutNatureNobel
β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor Stimulation
2002 StandoutNobel
Active mitochondria surrounding the pancreatic acinar granule region prevent spreading of inositol trisphosphate-evoked local cytosolic Ca2+ signals
1999
Characterization of Elementary Ca2+ Release Signals in NGF-Differentiated PC12 Cells and Hippocampal Neurons
1999
Differential modulation of the phases of a Ca2+ spike by the store Ca2+‐ATPase in human umbilical vein endothelial cells
1998
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
2008 StandoutNature
Propagation of the apoptotic signal by mitochondrial waves
2001
pp60v- Induction of Cyclin D1 Requires Collaborative Interactions between the Extracellular Signal-regulated Kinase, p38, and Jun Kinase Pathways
1999
Identification of an Extracellular Signal-regulated Kinase (ERK) Docking Site in Ribosomal S6 Kinase, a Sequence Critical for Activation by ERK in Vivo
1999
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Oxidation-induced changes in human lens epithelial cells 2. Mitochondria and the generation of reactive oxygen species
2006
Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca2+ release channel
2007 StandoutNobel
Quasi-synaptic calcium signal transmission between endoplasmic reticulum and mitochondria
1999
Prostaglandin E2‐induced sensitization of bradykinin‐evoked responses in rat dorsal root ganglion neurons is mediated by cAMP‐dependent protein kinase A
2000
Release and sequestration of calcium by ryanodine‐sensitive stores in rat hippocampal neurones
1997
Imaging of cAMP Levels and Protein Kinase A Activity Reveals That Retinal Waves Drive Oscillations in Second-Messenger Cascades
2006 StandoutNobel
Loss of Net as Repressor Leads to Constitutive Increased c-fos Transcription in Cervical Cancer Cells
2004 StandoutNobel
Mitochondria Suppress Local Feedback Activation of Inositol 1,4,5-Trisphosphate Receptors by Ca2+
1999
Formation and plasticity of GABAergic synapses: physiological mechanisms and pathophysiological implications
2003
Characterization of the human heart mitochondrial proteome
2003
A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology
2008 Standout
Genetic and Pharmacological Evidence for a Novel, Intermediate Phase of Long-Term Potentiation Suppressed by Calcineurin
1998 StandoutNobel
Stat3 as an Oncogene
1999 Standout
Cyclosporin A-insensitive Permeability Transition in Brain Mitochondria
2003
Calcium-induced calcium release in neurones
1996
Calcium Stores in Hippocampal Synaptic Boutons Mediate Short-Term Plasticity, Store-Operated Ca2+ Entry, and Spontaneous Transmitter Release
2001
Mitochondria: In Sickness and in Health
2012 Standout
Dysregulated IP3Signaling in Cortical Neurons of Knock-In Mice Expressing an Alzheimer's-Linked Mutation inPresenilin1Results in Exaggerated Ca2+Signals and Altered Membrane Excitability
2004
Mitochondria and Endoplasmic Reticulum: The Lethal Interorganelle Cross-Talk
2005
Artemisinins target the SERCA of Plasmodium falciparum
2003 Nature
Mitochondria, Oxidants, and Aging
2005 Standout
Microscopic properties of elementary Ca2+ release sites in non-excitable cells
2000 StandoutNobel
Mitochondria Are Excitable Organelles Capable of Generating and Conveying Electrical and Calcium Signals
1997
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
2011 StandoutNature
Adenosine and sleep–wake regulation
2004
Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors
2005 Standout
Phosphorylation and Functional Inactivation of TSC2 by Erk
2005 Standout
Soluble Interleukin-6 (IL-6) Receptor/IL-6 Fusion Protein Enhances in Vitro Differentiation of Purified Rat Oligodendroglial Lineage Cells
2002
Mitochondria Recycle Ca2+ to the Endoplasmic Reticulum and Prevent the Depletion of Neighboring Endoplasmic Reticulum Regions
2001
Microdomains of Intracellular Ca2+: Molecular Determinants and Functional Consequences
2005
Signaling—2000 and Beyond
2000 Standout
Control of apoptosis by IP3and ryanodine receptor driven calcium signals
2000
Malignant Gliomas in Adults
2008 Standout
α1 and α6 subunits specify distinct desensitization, deactivation and neurosteroid modulation of GABAA receptors containing the δ subunit
2002
Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activationofCREB
1998
Ryanodine receptor‐mediated intracellular calcium release in rat cerebellar Purkinje neurones.
1995
Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses
2004
Detection of a trigger zone of bradykinin-induced fast calcium waves in PC12 neurites
1996
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Calmodulin Controls Synaptic Strength via Presynaptic Activation of Calmodulin Kinase II
2010 StandoutNobel
Autophagy and Aging
2011 Standout
The induction of pain: an integrative review
1999
Involvement of apoptosis and calcium mobilization in tetrahydrobiopterin-induced dopaminergic cell death
2003
Fast confocal imaging of calcium released from stores in dendritic spines
1998
GABAA receptor changes in δ subunit‐deficient mice: Altered expression of α4 and γ2 subunits in the forebrain
2002
Hippocampal mossy fiber activity evokes Ca2+ release in CA3 pyramidal neurons via a metabotropic glutamate receptor pathway
2001
Phosphorylation of RIM1α by PKA Triggers Presynaptic Long-Term Potentiation at Cerebellar Parallel Fiber Synapses
2003 StandoutNobel
Extracellular Regulated Kinases (ERK) 1 and ERK2 Are Authentic Substrates for the Dual-specificity Protein-tyrosine Phosphatase VHR
1999
Altered Expression of the δ Subunit of the GABAAReceptor in a Mouse Model of Temporal Lobe Epilepsy
2004
Calcium Dynamics of Neocortical Ventricular Zone Cells
2000
Neuronal Calcium Signaling
1998 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Mitochondria and calcium: from cell signalling to cell death
2000
Protein Tyrosine Phosphatases in the Human Genome
2004 Standout
The Hallmarks of Aging
2013 Standout
Calcium Signaling
2007 Standout
Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death
1999
Angiotensin II-induced Down-regulation of Inositol Trisphosphate Receptors in WB Rat Liver Epithelial Cells
1997
Calcium stores in neurons and glia
1994
NADPH Oxidase-Dependent Regulation of T-Type Ca2+Channels and Ryanodine Receptors Mediate the Augmented Exocytosis of Catecholamines from Intermittent Hypoxia-Treated Neonatal Rat Chromaffin Cells
2010
Activation and co‐ordination of InsP3‐mediated elementary Ca2+ events during global Ca2+ signals in Xenopus oocytes
1998
The Type III Inositol 1,4,5-Trisphosphate Receptor Preferentially Transmits Apoptotic Ca2+ Signals into Mitochondria
2005
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Hormonally regulated α4β2δ GABAA receptors are a target for alcohol
2002
Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival
2007 Standout
The Stability of the G Protein-coupled Receptor-β-Arrestin Interaction Determines the Mechanism and Functional Consequence of ERK Activation
2003 StandoutNobel
A role for the polysialic acid – neural cell adhesion molecule in PDGF-induced chemotaxis of oligodendrocyte precursor cells
2003
Structural complexity and functional diversity of endoplasmic reticulum Ca2+ stores
2001
Biosynthesis of inositol trisphosphate receptors: selective association with the molecular chaperone calnexin
1999
Ethanol enhances α 4 β 3 δ and α 6 β 3 δ γ-aminobutyric acid type A receptors at low concentrations known to affect humans
2003
Activity-Dependent Calcium Sequestration in Dendrites of Hippocampal Neurons in Brain Slices
1997
Intact Synaptic GABAergic Inhibition and Altered Neurosteroid Modulation of Thalamic Relay Neurons in Mice Lacking δ Subunit
2003
Postsynaptic Calcineurin Activity Downregulates Synaptic Transmission by Weakening Intracellular Ca2+Signaling Mechanisms in Hippocampal CA1 Neurons
1997
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Responding to Hypoxia: Lessons From a Model Cell Line
2002
Ionic Basis for Plateau Potentials in Deep Dorsal Horn Neurons of the Rat Spinal Cord
1999
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
The mitochondrial permeability transition pore and its role in cell death
1999 Standout
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
2003 StandoutScience
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Tools and Tactics for the Optical Detection of Mercuric Ion
2008 Standout
Modulation of cell calcium signals by mitochondria.
1998
Neurosteroids Shift Partial Agonist Activation of GABAAReceptor Channels from Low- to High-Efficacy Gating Patterns
2003
The mammalian central nervous synaptic cleft contains a high density of periodically organized complexes
2005 StandoutNobel
Measurement of Intracellular Calcium
1999
Mitochondrial control of calcium-channel gating: A mechanism for sustained signaling and transcriptional activation in T lymphocytes
2000
Modulation of cell calcium signals by mitochondria
1998
Transient Mitochondrial Depolarizations Reflect Focal Sarcoplasmic Reticular Calcium Release in Single Rat Cardiomyocytes
1998
Mitochondria and Apoptosis
1998 StandoutScience
Responding to Hypoxia: Lessons From a Model Cell Line
2002
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Establishment and plasticity of neuronal polarity
1999
Ryanodine produces a low frequency stimulation‐induced NMDA receptor‐independent long‐term potentiation in the rat dentate gyrus in vitro.
1996
Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by δ subunit-containing GABA A receptors
2003
Enhanced Neurosteroid Potentiation of Ternary GABAAReceptors Containing the δ Subunit
2002
Metabolic Characterization of Tumor Cell-specific Protoporphyrin IX Accumulation After Exposure to 5-Aminolevulinic Acid in Human Colonic Cells¶
2002
The absence of a major Ca 2+ signaling pathway in GABAergic neurons of the hippocampus
1998
IP3Receptors, Mitochondria, and Ca2+Signaling: Implications for Aging
2011
All-or-None Ca2+Release from Intracellular Stores Triggered by Ca2+Influx through Voltage-Gated Ca2+Channels in Rat Sensory Neurons
1997
Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms
1999 StandoutScience
Polysialic acid governs T-cell development by regulating progenitor access to the thymus
2009 StandoutNobel
Regulation of mitochondrial ATP synthesis by calcium: Evidence for a long-term metabolic priming
1999
CREB: A Stimulus-Induced Transcription Factor Activated by A Diverse Array of Extracellular Signals
1999 Standout
Malignant glioma: genetics and biology of a grave matter
2001
Flirting in Little Space: The ER/Mitochondria Ca 2+ Liaison
2004
Neuronal Plasticity: Increasing the Gain in Pain
2000 StandoutScience
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Mitochondria Exert a Negative Feedback on the Propagation of Intracellular Ca2+ Waves in Rat Cortical Astrocytes
1999
Ryanodine Receptor Calcium Release Channels
2002
Stimulation of Elk1 Transcriptional Activity by Mitogen-activated Protein Kinases Is Negatively Regulated by Protein Phosphatase 2B (Calcineurin)
1999
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
2011 StandoutNobel
Works of Peter B. Simpson being referenced
α4β3δ GABAAReceptors Characterized by Fluorescence Resonance Energy Transfer-derived Measurements of Membrane Potential
2001
Chronic Activation of Muscarinic and Metabotropic Glutamate Receptors Down‐Regulates Type I Inositol 1,4,5‐Trisphosphate Receptor Expression in Cerebellar Granule Cells
1994
Mitochondria Support Inositol 1,4,5-Trisphosphate-mediated Ca2+ Waves in Cultured Oligodendrocytes
1996
Neuronal Ca2+ stores: activation and function
1995
Specialized distributions of mitochondria and endoplasmic reticulum proteins define Ca2+ wave amplification sites in cultured astrocytes
1998
High Density Distribution of Endoplasmic Reticulum Proteins and Mitochondria at Specialized Ca2+ Release Sites in Oligodendrocyte Processes
1997
Agonist‐Evoked Ca2+ Mobilization from Stores Expressing Inositol 1,4,5‐Trisphosphate Receptors and Ryanodine Receptors in Cerebellar Granule Neurones
1996
Mitochondrial Ca2+ uptake and release influence metabotropic and ionotropic cytosolic Ca2+ responses in rat oligodendrocyte progenitors
1998
High Throughput Fluorescence Assays for the Measurement of Mitochondrial Activity in Intact Human Neuroblastoma Cells
2001
Involvement of Intracellular Stores in the Ca2+ Responses to N‐Methyl‐D‐Aspartate and Depolarization in Cerebellar Granule Cells
1993
Role of mitochondrial Ca2+ regulation in neuronal and glial cell signalling1Published on the World Wide Web on December 3rd 1997.1
1998
Comparison of Type 2 Inositol 1,4,5‐Trisphosphate Receptor Distribution and Subcellular Ca2+ Release Sites that Support Ca2+ Waves in Cultured Astrocytes
1997
Role of sarcoplasmic/endoplasmic-reticulum Ca2+-ATPases in mediating Ca2+ waves and local Ca2+-release microdomains in cultured glia
1997
Intracellular signals and cytoskeletal elements involved in oligodendrocyte progenitor migration
1999
Characterization of ryanodine receptors in oligodendrocytes, type 2 astrocytes, and O‐2A progenitors
1998
Neurotransmitter- and Growth Factor-Induced cAMP Response Element Binding Protein Phosphorylation in Glial Cell Progenitors: Role of Calcium Ions, Protein Kinase C, and Mitogen-Activated Protein Kinase/Ribosomal S6 Kinase Pathway
1997