Citation Impact
Citing Papers
A Transient and Low-Populated Protein-Folding Intermediate at Atomic Resolution
2010 Science
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
Navigating the protein fitness landscape with Gaussian processes
2012 StandoutNobel
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
The spatial architecture of protein function and adaptation
2012 Nature
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
NMR Structure Determination for Larger Proteins Using Backbone-Only Data
2010 StandoutScienceNobel
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
Hypoxia-Inducible Factor Linked to Differential Kidney Cancer Risk Seen with Type 2A and Type 2B VHL Mutations
2007 StandoutNobel
Controlling entropy to tune the functions of intrinsically disordered regions
2014
mTOR Signaling in Growth Control and Disease
2012 Standout
The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection
2007 StandoutNobel
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
Probing Slow Chemical Exchange at Carbonyl Sites in Proteins by Chemical Exchange Saturation Transfer NMR Spectroscopy
2013
Dynamics and mechanisms of coupled protein folding and binding reactions
2012
Diversity of P450 enzymes in the biosynthesis of natural products
2012
Protein functional landscapes, dynamics, allostery: a tortuous path towards a universal theoretical framework
2010
Sulfatases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
Fractional 13C enrichment of isolated carbons using [1-13C]- or [2-13C]-glucose facilitates the accurate measurement of dynamics at backbone Cα and side-chain methyl positions in proteins
2007
Forces stabilizing proteins
2014
Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells
2014
Pattern Recognition Receptors and Inflammation
2010 Standout
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Diversification of Catalytic Function in a Synthetic Family of Chimeric Cytochrome P450s
2007 StandoutNobel
DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival
2009
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Sulfotransferases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
A folding-after-binding mechanism describes the recognition between the transactivation domain of c-Myb and the KIX domain of the CREB-binding protein
2012
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Solution structure of a minor and transiently formed state of a T4 lysozyme mutant
2011 StandoutNatureNobel
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
Improved protein structure prediction using potentials from deep learning
2020 StandoutNatureNobel
Mitochondrial metabolism of reactive oxygen species
2005
VHL, the story of a tumour suppressor gene
2014
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
An expanding arsenal of experimental methods yields an explosion of insights into protein folding mechanisms
2009
Allosteric regulation and catalysis emerge via a common route
2008
Phage-display technology – finding a needle in a vast molecular haystack
1999
The sweet and sour of cancer: glycans as novel therapeutic targets
2005
Allostery in Disease and in Drug Discovery
2013
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
Visualizing Side Chains of Invisible Protein Conformers by Solution NMR
2013
Frustration Sculpts the Early Stages of Protein Folding
2015
Conformational Plasticity and Structure/Function Relationships in Cytochromes P450
2010
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
Hierarchical Assembly of Model Cell Surfaces: Synthesis of Mucin Mimetic Polymers and Their Display on Supported Bilayers
2007 StandoutNobel
Allostery within a transcription coactivator is predominantly mediated through dissociation rate constants
2014
Single-Molecule Sensing Using Nanopores in Two-Dimensional Transition Metal Carbide (MXene) Membranes
2019
Sending Signals Dynamically
2009 Science
Heparan Sulfate Biosynthesis
2012
Anatomy of β-Strands at Protein–Protein Interfaces
2014
Studying “Invisible” Excited Protein States in Slow Exchange with a Major State Conformation
2012
Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
2009 StandoutNobel
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)
2014
von Hippel-Lindau Disease
2006 StandoutNobel
Tuning Protein Discrimination Through Altering the Sampling Interface Formed between the Analyte and the OmpG Nanopore
2021
Coupled Folding and Binding of the Disordered Protein PUMA Does Not Require Particular Residual Structure
2014
Redox-Controlled Selective Docking in a [2]Catenane Host
2013 StandoutNobel
Electrostatic origin of the mechanochemical rotary mechanism and the catalytic dwell of F1-ATPase
2011 StandoutNobel
Dramatic Decrease in CEST Measurement Times Using Multi‐Site Excitation
2018
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
Drug Discovery: A Historical Perspective
2000 StandoutScience
Direct observation of kinetic traps associated with structural transformations leading to multiple pathways of S-layer assembly
2012 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Short Linear Motifs: Ubiquitous and Functionally Diverse Protein Interaction Modules Directing Cell Regulation
2014
GLUTATHIONE TRANSFERASES
2004 Standout
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Single-Molecule Studies of Protein Folding
2008
A Chemical Reporter Strategy to Probe Glycoprotein Fucosylation
2006 StandoutNobel
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
An Analysis of the Effects of 1HN−1HN Dipolar Couplings on the Measurement of Amide Bond Vector Orientations in Invisible Protein States by Relaxation Dispersion NMR
2009
Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein
2019 StandoutNobel
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
The world of two-dimensional carbides and nitrides (MXenes)
2021 StandoutScience
Imaging the glycome
2008 StandoutNobel
The von Hippel-Lindau Tumor Suppressor Protein and Clear Cell Renal Carcinoma
2007 StandoutNobel
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
An Improved 15N Relaxation Dispersion Experiment for the Measurement of Millisecond Time-Scale Dynamics in Proteins
2007
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Allosteric Modulation of Substrate Binding within a Tetracationic Molecular Receptor
2015 StandoutNobel
Folding and Binding of an Intrinsically Disordered Protein: Fast, but Not ‘Diffusion-Limited’
2013
Measurement of Proton Chemical Shifts in Invisible States of Slowly Exchanging Protein Systems by Chemical Exchange Saturation Transfer
2012
Voltage-Induced Misfolding of Zinc-Replete ALS Mutant Superoxide Dismutase-1
2015
Single-Molecule Studies of Intrinsically Disordered Proteins
2014
The Protein Folding Problem
2008
Redox Control of the Binding Modes of an Organic Receptor
2015 StandoutNobel
Nonnative Interactions in the FF Domain Folding Pathway from an Atomic Resolution Structure of a Sparsely Populated Intermediate: An NMR Relaxation Dispersion Study
2011 StandoutNobel
Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450
2015 StandoutNobel
Works of Per Jemth being referenced
Reassessing a sparse energetic network within a single protein domain
2008
Investigating the Structural Plasticity of a Cytochrome P450
2009
Biosynthetic Oligosaccharide Libraries for Identification of Protein-binding Heparan Sulfate Motifs
2002
Single molecule unfolding and stretching of protein domains inside a solid-state nanopore by electric field
2013
The Transition State of Coupled Folding and Binding for a Flexible β-Finger
2012
Renal cell carcinoma risk in type 2 von Hippel–Lindau disease correlates with defects in pVHL stability and HIF-1α interactions
2005
An evolutionary approach to the design of glutathione-linked enzymes
1998
The transition state structure for coupled binding and folding of disordered protein domains
2013
Simulation and Experiment Conspire to Reveal Cryptic Intermediates and a Slide from the Nucleation-condensation to Framework Mechanism of Folding
2005
Fast Association and Slow Transitions in the Interaction between Two Intrinsically Disordered Protein Domains
2012
Reduction of thymine hydroperoxide by phospholipid hydroperoxide glutathione peroxidase and glutathione transferases
1997
An Ensemble of Theta Class Glutathione Transferases with Novel Catalytic Properties Generated by Stochastic Recombination of Fragments of Two Mammalian Enzymes
2002
The Structure of the Major Transition State for Folding of an FF Domain from Experiment and Simulation
2005
Processing of Macromolecular Heparin by Heparanase
2003
Helical Propensity in an Intrinsically Disordered Protein Accelerates Ligand Binding
2014
Energetic Pathway Sampling in a Protein Interaction Domain
2013
Sequence-specific Long Range Networks in PSD-95/Discs Large/ZO-1 (PDZ) Domains Tune Their Binding Selectivity
2011
Oligosaccharide Library-based Assessment of Heparan Sulfate 6-O-Sulfotransferase Substrate Specificity
2003
Demonstration of Long-Range Interactions in a PDZ Domain by NMR, Kinetics, and Protein Engineering
2006
The Kinetics of PDZ Domain-Ligand Interactions and Implications for the Binding Mechanism
2005
Demonstration by burst-phase analysis of a robust folding intermediate in the FF domain
2008
Chemical, Thermal, and Electric Field Induced Unfolding of Single Protein Molecules Studied Using Nanopores
2011
The binding mechanisms of intrinsically disordered proteins
2013
Biophysical Characterization of the Complex between Human Papillomavirus E6 Protein and Synapse-associated Protein 97
2010
Probing backbone hydrogen bonding in PDZ/ligand interactions by protein amide-to-ester mutations
2014
An On-pathway Intermediate in the Folding of a PDZ Domain
2007
Side-Chain Interactions Form Late and Cooperatively in the Binding Reaction between Disordered Peptides and PDZ Domains
2011
Conserved nucleation sites reinforce the significance of Phi value analysis in protein‐folding studies
2014
Single-Molecule Studies of Intrinsically Disordered Proteins Using Solid-State Nanopores
2013
A PDZ domain recapitulates a unifying mechanism for protein folding
2006
Phospholipid hydroperoxide glutathione peroxidase activity of human glutathione transferases
1998
Probing the Role of Backbone Hydrogen Bonds in Protein–Peptide Interactions by Amide-to-Ester Mutations
2013
PDZ Domains: Folding and Binding
2007
Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulation
2004
Comparison of successive transition states for folding reveals alternative early folding pathways of two homologous proteins
2008