Standout Papers
Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Gene Expression Preferentially Regulated by Tamoxifen in Breast Cancer Cells and Correlations with Clinical Outcome
2006
Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation
2002 StandoutNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Estrogen Dendrimer Conjugates that Preferentially Activate Extranuclear, Nongenomic Versus Genomic Pathways of Estrogen Action
2005
Inverse relationship between ER-β and SRC-1 predicts outcome in endocrine-resistant breast cancer
2004
A core gut microbiome in obese and lean twins
2008 StandoutNature
Gene expression profiling predicts clinical outcome of breast cancer
2002 StandoutNature
PACKMOL : A package for building initial configurations for molecular dynamics simulations
2009 Standout
Biological functions and clinical implications of oestrogen receptors alfa and beta in epithelial tissues
2008
Functional characteristics of a novel murine estrogen receptor-beta isoform, estrogen receptor-beta 2
2000
The histone acetylase PCAF is a nuclear receptor coactivator
1998
Loss of BRCA1 leads to an increased sensitivity to Bisphenol A
2010
Membrane Initiated Estrogen Signaling in Breast Cancer1
2006
The Orphan Nuclear Receptor SHP Inhibits Agonist-dependent Transcriptional Activity of Estrogen Receptors ERα and ERβ
1999
Regulated expression of estrogen receptor α and β mRNA in granule cells during development of the rat cerebellum
1999
Selective oestrogen receptor modulators: potential therapeutic applications
1998
Estrogen Receptors: How Do They Signal and What Are Their Targets
2007 Standout
β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
1999 StandoutNature
Retinoic acid receptors: From molecular mechanisms to cancer therapy
2014
Inflammation and metabolic disorders
2006 StandoutNature
Disentangling the molecular mechanisms of action of endogenous and environmental estrogens
2004
Molecular Cloning and Characterization of PELP1, a Novel Human Coregulator of Estrogen Receptor α
2001
Acetylation of nuclear receptors in cellular growth and apoptosis
2004
The Agonist Activity of Tamoxifen Is Inhibited by the Short Heterodimer Partner Orphan Nuclear Receptor in Human Endometrial Cancer Cells
2002
A comparison of transcriptional activation by ERα and ERβ
1999
Therapeutic potential of selective estrogen receptor modulators
1998
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Structural determinants of the BRCA1 : estrogen receptor interaction
2005
Non-monotonic dose–response relationship in steroid hormone receptor-mediated gene expression
2007
Antigen- and Cytokine-Driven Accumulation of Regulatory T Cells in Visceral Adipose Tissue of Lean Mice
2015
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion
2003
Estrogen receptor β
2002
The estrogen receptor family
1999
Oestrogen receptors – an overview
1999
Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma
2009
Estrogen Signaling: A Subtle Balance Between ER and ER
2003
Estrogen receptor α is a major mediator of 17β-estradiol’s atheroprotective effects on lesion size in Apoe–/– mice
2001 StandoutNobel
Potentiation of Human Estrogen Receptor α Transcriptional Activation through Phosphorylation of Serines 104 and 106 by the Cyclin A-CDK2 Complex
1999
IFN-Stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff
2002
The nuclear receptor ligand-binding domain: structure and function
1998
The Phosphoenolpyruvate Carboxykinase Gene Glucocorticoid Response Unit: Identification of the Functional Domains of Accessory Factors HNF3β (Hepatic Nuclear Factor-3β) and HNF4 and the Necessity of Proper Alignment of Their Cognate Binding Sites
1999
Phytoestrogens: a review of the present state of research
2003
The Protective Effects of Estrogen on the Cardiovascular System
1999 Standout
Ligand-Independent Recruitment of SRC-1 to Estrogen Receptor β through Phosphorylation of Activation Function AF-1
1999
Anti-hepatitis C Virus Activity of Tamoxifen Reveals the Functional Association of Estrogen Receptor with Viral RNA Polymerase NS5B
2007
The language of covalent histone modifications
2000 StandoutNature
Plasma membrane estrogen receptors
2009
Vitamin D Deficiency
2007 Standout
A role for oestrogens in the male reproductive system
1997 Nature
Functional Synergy between the Transcription Factor Sp1 and the Estrogen Receptor
1997
Endocrine Disruptors: Can Biological Effects and Environmental Risks Be Predicted?
2002
BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells
2006
Estrogen Receptor (ER) β Modulates ERα-Mediated Transcriptional Activation by Altering the Recruitment of c-Fos and c-Jun to Estrogen-Responsive Promoters
2005
Estrogen Receptors Beta4 and Beta5 Are Full Length Functionally Distinct ERβ Isoforms: Cloning from Human Ovary and Functional Characterization
2005
Transforming p21 Mutants and c-Ets-2 Activate the Cyclin D1 Promoter through Distinguishable Regions
1995
Ligand-, Cell-, and Estrogen Receptor Subtype (α/β)-dependent Activation at GC-rich (Sp1) Promoter Elements
2000
The Partial Agonist Activity of Antagonist-Occupied Steroid Receptors Is Controlled by a Novel Hinge Domain-Binding Coactivator L7/SPA and the Corepressors N-CoR or SMRT
1997
Identification of a new isoform of the human estrogen receptor-alpha (hER-alpha) that is encoded by distinct transcripts and that is able to repress hER-alpha activation function 1
2000
Nonbonding interactions of organic halogens in biological systems: implications for drug discovery and biomolecular design
2010
Role of protein methylation in chromatin remodeling and transcriptional regulation
2001
p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation
1998
Environmental hormones: Multiple pathways for response may lead to multiple disease outcomes
2010
The Complete Primary Structure of Human Estrogen Receptor β (hERβ) and Its Heterodimerization with ER αin Vivoandin Vitro
1998
Structure‐Function Relationships in Estrogen Receptors and the Characterization of Novel Selective Estrogen Receptor Modulators with Unique Pharmacological Profiles
2001
Antiestrogens upregulate estrogen receptor β expression and inhibit adrenocortical H295R cell proliferation
2005
Halogen bonding (X‐bonding): A biological perspective
2012
Estrogen-Induced Retinoic Acid Receptor α1 Gene Expression: Role of Estrogen Receptor-Sp1 Complex
1998
Mechanism of the nuclear receptor molecular switch
2004
Molecular mechanisms of oestrogen and SERMs in endometrial carcinogenesis
2006
What pharmacologists can learn from recent advances in estrogen signalling
2003
Genome-wide analysis of estrogen receptor binding sites
2006
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
Estrogen modulation of adrenoceptor responsiveness in the female rat pineal gland: differential expression of intracellular estrogen receptors
2004
Estrogen receptor and the SERM concept
1999
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
The estrogen receptor gene: Promoter organization and expression
1997
Expression of estrogen receptor-α and β mRNA in the developing and adult mouse striatum
1999
Novel estrogen receptor coregulators and signaling molecules in human diseases
2004
Growth factor receptor cross-talk with estrogen receptor as a mechanism for tamoxifen resistance in breast cancer
2003
Diet rapidly and reproducibly alters the human gut microbiome
2013 StandoutNature
Lessons learnt from structural studies of the oestrogen receptor
2006
The novel estrogen receptor‐β subtype: potential role in the cell‐ and promoter‐specific actions of estrogens and anti‐estrogens
1997
A Transcriptional Coactivator, Steroid Receptor Coactivator-3, Selectively Augments Steroid Receptor Transcriptional Activity
1998
Specific modulation of estrogen receptor mRNA isoforms in rat pituitary throughout the estrous cycle and in response to steroid hormones
1997
Characterization of a Membrane-Associated Estrogen Receptor in a Rat Hypothalamic Cell Line (D12)
2003
A structural biologist's view of the oestrogen receptor
2000
Advanced concepts in estrogen receptor biology and breast cancer endocrine resistance: implicated role of growth factor signaling and estrogen receptor coregulators
2005
Distribution of estrogen receptor beta (ERβ) mRNA in hypothalamus, midbrain and temporal lobe of spayed macaque: continued expression with hormone replacement
2000
Differential Recruitment of Coregulator Proteins Steroid Receptor Coactivator-1 and Silencing Mediator for Retinoid and Thyroid Receptors to the Estrogen Receptor-Estrogen Response Element by β-Estradiol and 4-Hydroxytamoxifen in Human Breast Cancer
2004
Activation of Nuclear Receptors
2003
An obesity-associated gut microbiome with increased capacity for energy harvest
2006 StandoutNature
An Additional Region of Coactivator GRIP1 Required for Interaction with the Hormone-binding Domains of a Subset of Nuclear Receptors
1999
Combinatorial roles of nuclear receptors in inflammation and immunity
2005
Molecular portraits of human breast tumours
2000 StandoutNature
Increased cortical bone mineral content but unchanged trabecular bone mineral density in female ERβ–/– mice
1999
AIB1 Is a Conduit for Kinase-Mediated Growth Factor Signaling to the Estrogen Receptor
2000
Thyroid hormones and the control of cell proliferation or cell differentiation: Paradox or duality?
2009
The Human Microbiome Project
2007 StandoutNature
Estrogen receptors in the human forebrain and the relation to neuropsychiatric disorders
2001
Coronary artery and cultured aortic smooth muscle cells express mRNA for both the classical estrogen receptor and the newly described estrogen receptor beta
1998
Expression of estrogen receptor alpha and beta during mouse embryogenesis
1999
GATA-3 is expressed in association with estrogen receptor in breast cancer
1999
Analysis of Estrogen Receptor Interaction with a Repressor of Estrogen Receptor Activity (REA) and the Regulation of Estrogen Receptor Transcriptional Activity by REA
2000
What We Talk About When We Talk About Fat
2014 Standout
The Estrogen Receptor β Subtype: A Novel Mediator of Estrogen Action in Neuroendocrine Systems
1998
Targets of activated steroid hormone receptors: basal transcription factors and receptor interacting proteins
1998
Human gut microbes associated with obesity
2006 StandoutNature
Production and Actions of Estrogens
2002 Standout
Diversity, stability and resilience of the human gut microbiota
2012 StandoutNature
Hormone-independent Transcriptional Activation and Coactivator Binding by Novel Orphan Nuclear Receptor ERR3
1999
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
2011 StandoutNature
The Multifaceted Mechanisms of Estradiol and Estrogen Receptor Signaling
2001
Halogen bonding in ligand–receptor systems in the framework of classical force fields
2011
Molecular Mechanisms, Physiological Consequences and Pharmacological Implications of Estrogen Receptor Action
2004
Estrogen rapid action via protein complex formation involving ERα and Src
2005
Mechanisms of endocrine resistance and novel therapeutic strategies in breast cancer
2005
Thyroid Hormone Activation of Transcription Is Potentiated by Activators of cAMP-dependent Protein Kinase
1996
Structural Insights into the Mode of Action of a Pure Antiestrogen
2001
Clinical value of the wild-type estrogen receptor β expression in breast cancer
2001
Estrogen Receptor β Is Coexpressed with ERα and PR and Associated with Nodal Status, Grade, and Proliferation Rate in Breast Cancer
2000
Binding Site Detection and Druggability Index from First Principles
2009
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Estrogens and ICI182,780 (Faslodex) Modulate Mitosis and Cell Death in Immature Cerebellar Neurons via Rapid Activation of p44/p42 Mitogen-Activated Protein Kinase
2003
A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3
2001 StandoutNobel
Enhanced Epidermal Growth Factor Receptor Signaling in MCF7 Breast Cancer Cells after Long-Term Culture in the Presence of the Pure Antiestrogen ICI 182,780 (Faslodex)*
2001
Conjugated Equine Estrogens Alone, but Not in Combination With Medroxyprogesterone Acetate, Inhibit Aortic Connective Tissue Remodeling After Plasma Lipid Lowering in Female Monkeys
1998
Role of Halogen Bonds in Thyroid Hormone Receptor Selectivity: Pharmacophore-Based 3D-QSSR Studies
2009
Tamoxifen-Bound Estrogen Receptor (ER) Strongly Interacts with the Nuclear Matrix Protein HET/SAF-B, a Novel Inhibitor of ER-Mediated Transactivation
2000
The Transcriptional Integrator CREB-Binding Protein Mediates Positive Cross Talk between Nuclear Hormone Receptors and the Hematopoietic bZip Protein p45/NF-E2
1997
Effects of Estrogen on the Vascular Injury Response in Estrogen Receptor α,β (Double) Knockout Mice
2001
Tissue Tregs
2016
Preliminary experience with pure antiestrogens.
2001
Estrogen Receptor β Inhibits Human Breast Cancer Cell Proliferation and Tumor Formation by Causing a G2 Cell Cycle Arrest
2004
RIP-140 Interacts with Multiple Nuclear Receptors by Means of Two Distinct Sites
1996
Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription
2000 StandoutNobel
EID3 is a novel EID family member and an inhibitor of CBP-dependent co-activation
2005
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Coactivator and Corepressor Regulation of the Agonist/Antagonist Activity of the Mixed Antiestrogen, 4-Hydroxytamoxifen
1997
Hormone-Dependent Coactivator Binding to a Hydrophobic Cleft on Nuclear Receptors
1998 Science
Orphan Nuclear Receptors: From Gene to Function*
1999
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
2000 StandoutNobel
The SMRT Corepressor Is Regulated by a MEK-1 Kinase Pathway: Inhibition of Corepressor Function Is Associated with SMRT Phosphorylation and Nuclear Export
2000
Peptide Antagonists of the Human Estrogen Receptor
1999 Science
Quantitative Analysis of Estrogen Receptor Proteins in Rat Mammary Gland*
2001
The NEDD8 Pathway Is Required for Proteasome-Mediated Degradation of Human Estrogen Receptor (ER)-α and Essential for the Antiproliferative Activity of ICI 182,780 in ERα-Positive Breast Cancer Cells
2003
Invited Review: Cell localization, physiology, and nongenomic actions of estrogen receptors
2001
Ligand-dependent Cross-talk between Steroid and Thyroid Hormone Receptors
1996
Halogen Bonding inside a Molecular Container
2012
Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.
1995
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
2002 StandoutScienceNobel
Selective Estrogen Receptor Modulators
2004
Nuclear Receptor-Binding Sites of Coactivators Glucocorticoid Receptor Interacting Protein 1 (GRIP1) and Steroid Receptor Coactivator 1 (SRC-1): Multiple Motifs with Different Binding Specificities
1998
Identification of a Functional Imperfect Estrogen-Responsive Element in the 5‘-Promoter Region of the Human Cathepsin D Gene
1997
Age-related changes in human oestrogen receptor α function and levels in osteoblasts
1998
Crystallographic comparison of the estrogen and progesterone receptor’s ligand binding domains
1998
Basic Guide to the Mechanisms of Antiestrogen Action
1998
A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP
2002
Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?
1999 Standout
Generation and reproductive phenotypes of mice lacking estrogen receptor β
1998 StandoutNobel
Nuclear hormone receptors: ligand-activated regulators of transcription and diverse cell responses
1996
Development of an ER Action Indicator Mouse for the Study of Estrogens, Selective ER Modulators (SERMs), and Xenobiotics
2001
Estrogen Receptor-α Is Developmentally Regulated during Osteoblast Differentiation and Contributes to Selective Responsiveness of Gene Expression
1998
Expression and Localization of Estrogen Receptor-β in Murine and Human Bone
1999
LIGAND CONTROL OF COREGULATOR RECRUITMENT TO NUCLEAR RECEPTORS
2004
Physiological and Molecular Basis of Thyroid Hormone Action
2001 Standout
CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription.
1996
Cell Cycle Progression Stimulated by Tamoxifen-Bound Estrogen Receptor-α and Promoter-Specific Effects in Breast Cancer Cells Deficient in N-CoR and SMRT
2005
Mechanisms of Estrogen Action
2001 Standout
A Negative Coregulator for the Human ER
2002
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Plasma Membrane Estrogen Receptors Exist and Functions as Dimers
2004
Structural Basis for an Unexpected Mode of SERM-Mediated ER Antagonism
2005
A role for estrogen receptor β in the regulation of growth of the ventral prostate
2001
Integrin Signaling
1999 StandoutScience
The Molecular Pharmacology of SERMs
1999
Estrogen receptor (ER) β, a modulator of ERα in the uterus
2000
BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor
2001
Molecular Determinants of the Estrogen Receptor-Coactivator Interface
1999
The quinone reductase gene: A unique estrogen receptor-regulated gene that is activated by antiestrogens
1997
Thyroid Hormone Regulation of Metabolism
2014 Standout
Coregulator Function: A Key to Understanding Tissue Specificity of Selective Receptor Modulators
2004
Molecular Determinants for the Tissue Specificity of SERMs
2002 Science
Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
2012 Standout
AF-2 Activity and Recruitment of Steroid Receptor Coactivator 1 to the Estrogen Receptor Depend on a Lysine Residue Conserved in Nuclear Receptors
1997
Minireview: Extranuclear Steroid Receptors: Roles in Modulation of Cell Functions
2010
Nuclear Receptor Coregulators: Cellular and Molecular Biology*
1999 Standout
Three Functional Classes of Transcriptional Activation Domains
1996
Functional Analysis of a Novel Estrogen Receptor-β Isoform
1999
GRIP1, a Transcriptional Coactivator for the AF-2 Transactivation Domain of Steroid, Thyroid, Retinoid, and Vitamin D Receptors
1997
Estrogen Receptor β Activates the Human Retinoic Acid Receptorα -1 Promoter in Response to Tamoxifen and Other Estrogen Receptor Antagonists, but Not in Response to Estrogen
1999
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Recruitment of Histone Deacetylase 4 to the N-Terminal Region of Estrogen Receptor α
2005
Estrogen receptor-dependent regulation of sensory neuron survival in developing dorsal root ganglion
1999
Translating the Histone Code
2001 StandoutScience
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Transcriptional Activation of Insulin-Like Growth Factor-Binding Protein-4 by 17β-Estradiol in MCF-7 Cells: Role of Estrogen Receptor-Sp1 Complexes*
1999
Estrogen Receptor β: An Overview and Update
2008
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Rapid screening of environmental chemicals for estrogen receptor binding capacity.
1998
The Orphan Nuclear Receptor SHP Utilizes Conserved LXXLL-Related Motifs for Interactions with Ligand-Activated Estrogen Receptors
2000
A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle
2010 StandoutNobel
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
The Halogen Bond
2016 Standout
A PCR Analysis of ERα and ERβ mRNA Abundance in Rats and the Effect of Ovariectomy
1999
Biochemical and Structural Evaluation of Highly Selective 2-Arylbenzoxazole-Based Transthyretin Amyloidogenesis Inhibitors
2007
Estrogen Receptor Subtype-Selective Ligands: Asymmetric Synthesis and Biological Evaluation of cis- and trans-5,11-Dialkyl- 5,6,11,12-tetrahydrochrysenes
1999
Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation.
1996
Cell Membrane and Nuclear Estrogen Receptors (ERs) Originate from a Single Transcript: Studies of ERα and ERβ Expressed in Chinese Hamster Ovary Cells
1999
Identification of Estrogen Receptor β2, A Functional Variant of Estrogen Receptor β Expressed in Normal Rat Tissues
1998
Serine/Threonine Protein Kinase Stk Is Required for Virulence, Stress Response, and Penicillin Tolerance in Streptococcus pyogenes
2011
Estrogen-Induced c-fos Protooncogene Expression in MCF-7 Human Breast Cancer Cells: Role of Estrogen Receptor Sp1 Complex Formation*
1998
Thyroid Hormone Receptor Can Modulate Retinoic Acid-Mediated Axis Formation in Frog Embryogenesis
1993
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
Noncalcemic Actions of Vitamin D Receptor Ligands
2005
Estradiol Modulates bcl-2 in Cerebral Ischemia: A Potential Role for Estrogen Receptors
1999
Cross-Talk between Bone Morphogenic Proteins and Estrogen Receptor Signaling
2002
Identification of Tamoxifen-Induced Coregulator Interaction Surfaces within the Ligand-Binding Domain of Estrogen Receptors
2004
Transcriptional Activation of c-fos Protooncogene by 17β-Estradiol: Mechanism of Aryl Hydrocarbon Receptor-Mediated Inhibition
1999
Estrogenic responses in estrogen receptor-α deficient mice reveal a distinct estrogen signaling pathway
1997
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Regulation of Transcription by a Protein Methyltransferase
1999 Science
Estrogen inhibits the vascular injury response in estrogen receptor β-deficient female mice
1999 StandoutNobel
Genomic Targets of Nuclear Estrogen Receptors
2004
Works of Paul Webb being referenced
Distinct signatures of diversifying selection revealed by genome analysis of respiratory tract and invasive bacterial populations
2011
Structural Rearrangements in the Thyroid Hormone Receptor Hinge Domain and Their Putative Role in the Receptor Function
2006
Oestrogen Receptor Function at Classical and Alternative Response Elements
2000
Selective modulation of thyroid hormone receptor action
2001
Estrogen receptor pathways to AP-1
2000
Role of direct interaction in BRCA1 inhibition of estrogen receptor activity
2001
The genomic organisation, sequence and functional analysis of the 5′flanking region of the chicken estrogen receptor gene
1994
Anti-obesity, anti-diabetic, and lipid lowering effects of the thyroid receptor β subtype selective agonist KB-141
2008
Structural Insight into the Mode of Action of a Direct Inhibitor of Coregulator Binding to the Thyroid Hormone Receptor
2007
Thyroid Hormone Response Element Organization Dictates the Composition of Active Receptor
2007
Potentiation of Estrogen Receptor Activation Function 1 (AF-1) by Src/JNK through a Serine 118-Independent Pathway
2001
ERβ Binds N-CoR in the Presence of Estrogens via an LXXLL-like Motif in the N-CoR C-terminus
2003
Selective activation of thyroid hormone signaling pathways by GC-1: a new approach to controlling cholesterol and body weight
2004
An Antiestrogen-responsive Estrogen Receptor-α Mutant (D351Y) Shows Weak AF-2 Activity in the Presence of Tamoxifen
2000
Class II Major Histocompatibility Complex Plays an Essential Role in Obesity-Induced Adipose Inflammation
2013
Discovery of Small Molecule Inhibitors of the Interaction of the Thyroid Hormone Receptor with Transcriptional Coregulators
2005
Structure-Based Design and Synthesis of a Thyroid Hormone Receptor (TR) Antagonist
2002
A conserved lysine in the estrogen receptor DNA binding domain regulates ligand activation profiles at AP-1 sites, possibly by controlling interactions with a modulating repressor
2004
Thyroid hormone mimetics: potential applications in atherosclerosis, obesity and type 2 diabetes
2009
MOLECULAR AND STRUCTURAL BIOLOGY OF THYROID HORMONE RECEPTORS
1998
Differential SERM Effects on Corepressor Binding Dictate ERα Activity in Vivo
2003
Design of thyroid hormone receptor antagonists from first principles
2002
Thyroxine-Thyroid Hormone Receptor Interactions
2004
The Nuclear Receptor Corepressor (N-CoR) Contains Three Isoleucine Motifs (I/LXXII) That Serve as Receptor Interaction Domains (IDs)
2000
Opposing Action of Estrogen Receptors α and β on Cyclin D1 Gene Expression
2002
Estrogen Receptor Activation Function 1 Works by Binding p160 Coactivator Proteins
1998
Transcriptional Activities of Estrogen and Glucocorticoid Receptors Are Functionally Integrated at the AP-1 Response Element*
1997
Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice
2005
Conformational adaptation of nuclear receptor ligand binding domains to agonists: Potential for novel approaches to ligand design
2005
The limits of the cellular capacity to mediate an estrogen response.
1992
Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens.
1995
Novel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based Design
2005
Molecular Dynamics Simulations of Ligand Dissociation from Thyroid Hormone Receptors: Evidence of the Likeliest Escape Pathway and Its Implications for the Design of Novel Ligands
2005
Identification of a Structural Determinant Necessary for the Localization and Function of Estrogen Receptor α at the Plasma Membrane
2003
The Estrogen Receptor Enhances AP-1 Activity by Two Distinct Mechanisms with Different Requirements for Receptor Transactivation Functions
1999
Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens
1995
p300 Modulates the BRCA1 inhibition of estrogen receptor activity.
2002
Positive and negative modulation of Jun action by thyroid hormone receptor at a unique AP1 site.
1993
The Estrogen Receptor Enhances AP-1 Activity by Two Distinct Mechanisms with Different Requirements for Receptor Transactivation Functions
1999
Quantification of Ligand-Regulated Nuclear Receptor Corepressor and Coactivator Binding, Key Interactions Determining Ligand Potency and Efficacy for the Thyroid Hormone Receptor
2008
Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways
2013
Multiple Signal Input and Output Domains of the 160-Kilodalton Nuclear Receptor Coactivator Proteins
1999
Adaptation to overeating in lean and overweight men and women.
1983
Transcriptional Activators Differ in Their Responses to Overexpression of TATA-Box-Binding Protein
1995
Estrogen Receptor Activation Function 1 Works by Binding p160 Coactivator Proteins
1998
Differential Ligand Activation of Estrogen Receptors ERα and ERβ at AP1 Sites
1997 StandoutScience
A surface on the androgen receptor that allosterically regulates coactivator binding
2007
Eukaryotic regulatory elements lurking in plasmid DNA: the activator protein-1 site in pUC.
1994
Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor
2003
Thyroid hormone receptor and lipid regulation.
2010