Paul Schaefer

Integrated Array-Comparative Genomic Hybridization and Expression Array Profiles Identify Clinically Relevant Molecular Subtypes of Glioblastoma

Combined Modality Treatment of Resectable and Borderline Resectable Pancreas Cancer: Expert Consensus Statement

TOR Signaling in Growth and Metabolism

Adjuvant Chemoradiation for Pancreatic Adenocarcinoma: The Johns Hopkins Hospital—Mayo Clinic Collaborative Study

WGCNA: an R package for weighted correlation network analysis

Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Effect of Maintenance Therapy With Varenicline on Smoking Cessation<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>

Human Equilibrative Nucleoside Transporter 1 Levels Predict Response to Gemcitabine in Patients With Pancreatic Cancer

Elements of cancer immunity and the cancer–immune set point

Pancreatic cancer

IDH1andIDH2Mutations in Gliomas

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

Randomized Comparison of a Nicotine Inhaler and Bupropion for Smoking Cessation and Relapse Prevention

AKT/PKB Signaling: Navigating Downstream

Preoperative/Neoadjuvant Therapy in Pancreatic Cancer: A Systematic Review and Meta-analysis of Response and Resection Percentages

Adjuvant Chemotherapy With Gemcitabine and Long-term Outcomes Among Patients With Resected Pancreatic Cancer

The biology and management of non-small cell lung cancer

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

Reduced Expression of PTEN Protein and Its Prognostic Implications in Invasive Ductal Carcinoma of the Breast

Advanced pancreatic carcinoma: current treatment and future challenges

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Chemotherapy for advanced gastric cancer

Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer

Prevention of VTE in Nonsurgical Patients

Factors influencing survival in high-grade gliomas

Results and patterns of failure in patients treated with adjuvant combined chemoradiation therapy for resected pancreatic adenocarcinoma

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

Multicenter phase II trial of adjuvant therapy for resected pancreatic cancer using cisplatin, 5-fluorouracil, and interferon-alfa-2b–based chemoradiation: ACOSOG Trial Z05031

Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma

Nicotine replacement therapy for smoking cessation

Targeting the phosphoinositide 3-kinase pathway in cancer

Pancreatic Adenocarcinoma

Docetaxel plus Prednisone or Mitoxantrone plus Prednisone for Advanced Prostate Cancer

Mechanisms of Disease: genetic predictors of response to treatment in brain tumors

Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme

Recent advances in the molecular genetics of primary gliomas

Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer

Targeted Molecular Therapy of GBM

Malignant Gliomas in Adults

Prevention of Venous Thromboembolism

Immunohistochemical Detection of EGFRvIII in High Malignancy Grade Astrocytomas and Evaluation of Prognostic Significance

A Model to Select Chemotherapy Regimens for Phase III Trials for Extensive-Stage Small-Cell Lung Cancer

Results of combined‐modality therapy for limited‐stage small cell lung carcinoma in the elderly

Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Adjuvant Chemoradiation Therapy for Adenocarcinoma of the Distal Pancreas

Prevention of Venous Thromboembolism

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

Pancreatic Cancer

Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

A Randomized Placebo-Controlled Clinical Trial of 5 Smoking Cessation Pharmacotherapies

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

Capecitabine and Oxaliplatin for Advanced Esophagogastric Cancer

The PI3K Pathway in Human Disease

Low Total Lymphocyte Count Is Associated with Poor Survival in Patients with Resected Pancreatic Adenocarcinoma Receiving a GM-CSF Secreting Pancreatic Tumor Vaccine

Effects of a Palliative Care Intervention on Clinical Outcomes in Patients With Advanced Cancer

Phase III trial comparing intensive induction chemoradiotherapy (60 Gy, infusional 5-FU and intermittent cisplatin) followed by maintenance gemcitabine with gemcitabine alone for locally advanced unresectable pancreatic cancer. Definitive results of the 2000–01 FFCD/SFRO study

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

The course of neurocognitive functioning in high-grade glioma patients1

Brain Tumors

Fluorouracil-based Chemoradiation with Either Gemcitabine or Fluorouracil Chemotherapy after Resection of Pancreatic Adenocarcinoma: 5-Year Analysis of the U.S. Intergroup/RTOG 9704 Phase III Trial

Pancreatic cancer

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis

Gene expression microarray analysis reveals YKL-40 to be a potential serum marker for malignant character in human glioma.

A Lethally Irradiated Allogeneic Granulocyte-Macrophage Colony Stimulating Factor-Secreting Tumor Vaccine for Pancreatic Adenocarcinoma

Selection pressures of TP53 mutation and microenvironmental location influence epidermal growth factor receptor gene amplification in human glioblastomas.

Nicotine replacement therapy for smoking cessation

Pten signaling in gliomas

Chemotherapy in Advanced Gastric Cancer: A Systematic Review and Meta-Analysis Based on Aggregate Data

FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

Postresection CA 19-9 Predicts Overall Survival in Patients With Pancreatic Cancer Treated With Adjuvant Chemoradiation: A Prospective Validation by RTOG 9704

Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target

Where do we stand in the treatment of relapsed acute lymphoblastic leukemia?

Many-legged maneuverability: dynamics of turning in hexapods

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

Matrix Metalloproteinases As Novel Biomarker s and Potential Therapeutic Targets in Human Cancer

The Biology and Clinical Relevance of the PTEN Tumor Suppressor Pathway

Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine.

Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.

Phase I/II Trial of Erlotinib and Temozolomide With Radiation Therapy in the Treatment of Newly Diagnosed Glioblastoma Multiforme: North Central Cancer Treatment Group Study N0177

Induction of CD8⁺T-Cell Responses Against Novel Glioma–Associated Antigen Peptides and Clinical Activity by Vaccinations With α-Type 1 Polarized Dendritic Cells and Polyinosinic-Polycytidylic Acid Stabilized by Lysine and Carboxymethylcellulose in Patients With Recurrent Malignant Glioma

Randomized Comparison of a Nicotine Inhaler and Bupropion for Smoking Cessation and Relapse Prevention

Genetic and signaling pathway alterations in glioblastoma relevance to novel targeted therapies

Multistage nanoparticle delivery system for deep penetration into tumor tissue

Neurons Containing NADPH-Diaphorase Are Selectively Resistant to Quinolinate Toxicity

Translational Therapeutic Opportunities in Ductal Adenocarcinoma of the Pancreas

BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline

T cell exclusion, immune privilege, and the tumor microenvironment

Genetic Pathways to Glioblastoma

Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration

Prognostic Effect of Epidermal Growth Factor Receptor and EGFRvIII in Glioblastoma Multiforme Patients

Clinical Benefit and Quality of Life in Patients With Advanced Pancreatic Cancer Receiving Gemcitabine Plus Capecitabine Versus Gemcitabine Alone: A Randomized Multicenter Phase III Clinical Trial—SAKK 44/00–CECOG/PAN.1.3.001

Serum IgE, Tumor Epidermal Growth Factor Receptor Expression, and Inherited Polymorphisms Associated with Glioma Survival

Neurobehavioral Status and Health-Related Quality of Life in Newly Diagnosed High-Grade Glioma Patients

Quality of Life Supersedes the Classic Prognosticators for Long-Term Survival in Locally Advanced Non–Small-Cell Lung Cancer: An Analysis of RTOG 9801

How Animals Move: An Integrative View

Correlation of O⁶-Methylguanine Methyltransferase (MGMT) Promoter Methylation With Clinical Outcomes in Glioblastoma and Clinical Strategies to Modulate MGMT Activity

Phase II Trial of Temsirolimus (CCI-779) in Recurrent Glioblastoma Multiforme: A North Central Cancer Treatment Group Study

Where do we stand in the treatment of relapsed acute lymphoblastic leukemia?

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

YKL-40 Expression is Associated with Poorer Response to Radiation and Shorter Overall Survival in Glioblastoma

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

Effects of radiation and chemotherapy on cognitive function in patients with high-grade glioma.

Randomized double-blind placebo-controlled trial of cisplatin and etoposide plus megestrol acetate/placebo in extensive-stage small-cell lung cancer: a North Central Cancer Treatment Group study.

Fluorouracil vs Gemcitabine Chemotherapy Before and After Fluorouracil-Based Chemoradiation Following Resection of Pancreatic Adenocarcinoma

PTEN Mutation, EGFR Amplification, and Outcome in Patients With Anaplastic Astrocytoma and Glioblastoma Multiforme

Phase III trial comparing chemotherapy plus once-daily or twice-daily radiotherapy in Stage III non-small-cell lung cancer 1 1This study was conducted as a collaborative trial of the North Central Cancer Treatment Group and Mayo Clinic. Additional participating institutions included Cedar Rapids Oncology Project CCOP, Cedar Rapids, IA; Meritcare Hospital CCOP, Fargo, ND; Sioux Community Cancer Consortium, Sioux Falls, SD; Geisinger Clinical Oncology Program, Danville, PA (Suresh Nair, M.D.); Rapid City Regional Oncology Group, Rapid City, SD (Larry P. Ebbert, M.D.), Saskatchewan Cancer Centre, Saskatoon, Saskatchewan, Canada; Allan Blair Cancer Centre, Regina, Saskatchewan, Canada (Maria Tria Tirona, M.D.); Scottsdale CCOP, Scottsdale, AZ (Tom R. Fitch, M.D.); Carle Cancer Center CCOP, Urbana, IL (Kendrith M. Rowland, M.D.); Medcenter One Health Systems, Bismarck, ND (Ferdinand Addo, M.D.); Altru Health Systems, Grand Forks, ND (Daniel J. Walsh, M.D.); Siouxland Hematology-Oncology Associates, Sioux City, IA (John C. Michalak, M.D.); and CentreCare Clinic, St. Cloud, MN (Harold E. Windschitl, M.D.).

Long-term results of a phase III trial comparing once-daily radiotherapy with twice-daily radiotherapy in limited-stage small-cell lung cancer

Clinicopathologic study of 85 similarly treated patients with anaplastic astrocytic tumors

Low-Molecular-Weight Heparin in Patients With Advanced Cancer: A Phase 3 Clinical Trial

Mortality associated with daily bolus 5‐fluorouracil/leucovorin administered in combination with either irinotecan or oxaliplatin

A patient-level meta-analytic investigation of the prognostic significance of baseline quality of life (QOL) for overall survival (OS) among 3,704 patients participating in 24 North Central Cancer Treatment Group (NCCTG) and Mayo Clinic Cancer Center (MC) oncology clinical trials

Motion analysis of escape movements evoked by tactile stimulation in the cockroach Periplaneta americana

Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia

Nicotine Patch Therapy Based on Smoking Rate Followed by Bupropion for Prevention of Relapse to Smoking

Quinolinic acid evokes [3H]acetylcholine release in striatal slices: Mediation by NMDA-type excitatory amino acid receptors

Gemcitabine, Cisplatin, and Radiotherapy for Patients With Locally Advanced Pancreatic Adenocarcinoma: Results of the North Central Cancer Treatment Group Phase II Study N9942