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Citing Papers

Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
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2010 StandoutScience
Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
2004 StandoutScience
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
2011 StandoutScience
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
Small assemblies of unmodified amyloid β-protein are the proximate neurotoxin in Alzheimer’s disease
2004
Therapeutic strategies for Alzheimer's disease
2002
Inflammation and Alzheimer's disease
2000 Standout
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
1996 StandoutNature
Brain matrix metalloproteinase 1 levels are elevated in Alzheimer's disease
2000
Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system
1993
Presenilins are essential for regulating neurotransmitter release
2009 StandoutNatureNobel
The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation
1995 Standout
Some aspects of the neurotransmitter control of anterior pituitary function
1989
Conditional Inactivation of Presenilin 1 Prevents Amyloid Accumulation and Temporarily Rescues Contextual and Spatial Working Memory Impairments in Amyloid Precursor Protein Transgenic Mice
2005
Rat homolog of mouse interleukin-1 receptor accessory protein: cloning, localization and modulation studies
1996
Contrasting effects of pituitary adenylate cyclase activating polypeptide (PACAP) on in vivo and in vitro prolactin and growth hormone release in male rats
1992
Peptide‐ and transmitter‐containing neurons in the mediobasal hypothalamus and their relation to GABAergic systems: Possible roles in control of prolactin and growth hormone secretion
1988
Deciphering the Molecular Basis of Memory Failure in Alzheimer's Disease
2004
Interleukin-1 in adrenal chromaffin cells
1989
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Time Course of the Development of Alzheimer-like Pathology in the Doubly Transgenic PS1+APP Mouse
2002
A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice
2016
Estrogen effects on the tuberoinfundibular dopaminergic system in the female rat brain
1990
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by β-amyloid fibrils
2003
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
Corticotropin-Releasing Factor Modulates the Immune Response to Stress in the Rat*
1991
Nerve Growth Factor in Pituitary Development and Pituitary Tumors
1998
How the Blood Talks to the Brain Parenchyma and the Paraventricular Nucleus of the Hypothalamus During Systemic Inflammatory and Infectious Stimuli
2000
Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model
2002
Intrinsic Pituitary Interleukin-1β Is Induced by Bacterial Lipopolysaccharide**
1990
Possible involvement of vasoactive intestinal polypeptide in the central stimulating action of pituitary adenylate cyclase-activating polypeptide on prolactin secretion in the rat
1995
Monokine production by microglial cell clones
1989
Systematic presence of GABA-immunoreactivity in the tubero-infundibular and tubero-hypophyseal dopaminergic axonal systems: an ultrastructural immunogold study on several mammals
1991
Neuroendocrine regulation of in vivo cytokine production and effects: I. In vivo regulatory networks involving the neuroendocrine system, interleukin-1 and tumor necrosis factor-α
1989
Production of Interleukin-6 by Anterior Pituitary Cells Is Stimulated by Increased Intracellular Adenosine 3′,5′ Monophosphate and Vasoactive Intestinal Peptide*
1990
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
2008 Standout
Network antibodies identify nuclear lamin B as a physiological attachment site for peripherin intermediate filaments
1991 StandoutNobel
Monoclonal antibodies that target pathological assemblies of Aβ
2006
Role of Nitric Oxide in the Neuroendocrine Responses to Cytokinesa
1998
Immune-Neuro-Endocrine Interactions: Facts and Hypotheses
1996
Amyloid β-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin
2008
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
TRANSFORMING GROWTH FACTOR-β1 INHIBITS PROLACTIN SECRETION AND LACTOTROPIC CELL PROLIFERATION IN THE PITUITARY OF OESTROGEN-TREATED FISCHER 344 RATS
1997
Interleukin 1-induced pathophysiology: Induction of cytokines, development of histopathologic changes, and immunopharmacologic intervention
1989
Protein folding and misfolding
2003 StandoutNature
Protein O-Mannosylation in the Murine Brain: Occurrence of Mono-O-Mannosyl Glycans and Identification of New Substrates
2016
Correlation between cognitive deficits and Aβ deposits in transgenic APP+PS1 mice
2001
Effects of Pituitary Adenylate Cyclase‐Activating Polypeptide (PACAP) and Vasoactive Intestinal Polypeptide (VIP) on Prolactin, Luteinizing Hormone and Growth Hormone Secretion in the Ewe
1994
Aβ Immunotherapy Leads to Clearance of Early, but Not Late, Hyperphosphorylated Tau Aggregates via the Proteasome
2004
Glial and neuronal control of brain blood flow
2010 StandoutNature
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Hypothalamic prostaglandin E2 during lipopolysaccharide-induced fever in guinea pigs
1996
The origin and differentiation of microglial cells during development
1998
Peptide‐Based Inhibitors of Amyloid Assembly
2006
Cytokine, Sickness Behavior, and Depression
2009
Interleukin-1β analogues with markedly reduced pyrogenic activity can stimulate secretion of adrenocorticotropic hormone in rats
1990
ACTH response induced by interleukin-1 is mediated by CRF secretion stimulated by hypothalamic PGE
1990
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
1998 StandoutNature
The Immune-Hypothalamic-Pituitary-Adrenal Axis*
1989
Immunoregulatory properties of growth hormone and prolactin
1996
The Obese Strain of Chickens: An Animal Model with Spontaneous Autoimmune Thyroiditis
1989
Biological basis of the behavior of sick animals
1988 Standout
Bioactive peptides in anterior pituitary cells
1994
Type 1 interleukin‐1 receptor in the rat brain: Distribution, regulation, and relationship to sites of IL‐1–induced cellular activation
1995
APP Processing and Synaptic Function
2003
Receptors for interleukin-1 (α and β) in mouse brain: Mapping and neuronal localization in hippocampus
1991
Does my mouse have Alzheimer's disease?
2002
Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory
2003
The metabolic effects of tumor necrosis factor and other cytokines
1991
Origin and physiological roles of inflammation
2008 StandoutNature
Anterior Pituitary Hypoplasia and Dwarfism in Mice Lacking the Dopamine Transporter
1997
Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells
1989 Standout
Distinct and Non-Redundant Roles of Microglia and Myeloid Subsets in Mouse Models of Alzheimer's Disease
2011
Cytokines as modulators of the hypothalamus-pituitary-adrenal axis
1991
Development and Heterogeneity of Prolactin Cells
1995
Pituitary adenylate cyclase-activating polypeptide (PACAP) increases prolactin release and tuberoinfundibular dopaminergic neuronal activity
1994
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Amyloid Reduction by Amyloid-  Vaccination Also Reduces Mouse Tau Pathology and Protects from Neuron Loss in Two Mouse Models of Alzheimer's Disease
2009
Interleukin-1 Immunoreactive Innervation of the Human Hypothalamus
1988 Science
Vaccination with soluble Aβ oligomers generates toxicity‐neutralizing antibodies
2001
Differential activity of interleukin 1α and interleukin 1β in the stimulation of the immune response in vivo
1990
Adrenocorticotropic hormone-releasing activities of interleukins in a homologous invivo system
1989
Intercellular Communication Within the Anterior Pituitary Influencing the Secretion of Hypophysial Hormones*
1992
Aβ-Induced Vascular Oxidative Stress and Attenuation of Functional Hyperemia in Mouse Somatosensory Cortex
2004
Dopamine uptake: A review of progress in the last decade
1990
An Inhibitory Effect of Interleukin-la on Basal Gonadotropin Release in the Ovariectomized Rhesus Monkey: Reversal by a Corticotropin-Releasing Factor Antagonist*
1991
Interleukin-1 Stimulates Interleukin-6 Release from Rat Anterior Pituitary Cellsin Vitro*
1991
Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report
2003 Standout
The inflammatory reflex
2002 StandoutNature
In the Mouse, the Activation of the Hypothalamic Pituitary-Adrenal Axis by a Lipopolysaccharide (Endotoxin) Is Mediated through Interleukin-1*
1989
The molecular neurobiology of depression
2008 StandoutNature
Antibodies against β‐amyloid reduce aβ oligomers, glycogen synthase kinase‐3β activation and τ phosphorylation in vivo and in vitro
2005
Immunomodulators and feeding regulation: A humoral link between the immune and nervous systems
1989
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3
1998 Nature
Molecular Mechanisms of Amyloidosis
2003 Standout
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers
2007
Relationship between antigen-induced immune stimulation and activation of the hypothalamic-pituitary-adrenal axis in the rat.
1993
Genetically engineered mouse models of neurodegenerative diseases
2002
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation
2000 StandoutNobel
Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats.
1989
Identification of soluble interleukin-1 binding protein in cell-free supernatants. Evidence for soluble interleukin-1 receptor.
1990
Prostanoid Receptors: Structures, Properties, and Functions
1999 Standout
Alzheimer's disease-affected brain: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss
2003
Thermal and PGE2 sensitivity of the organum vasculosum lamina terminalis region and preoptic area in rat brain slices.
1992
Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model
2008 StandoutNobel
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Molecular aspects of aging
1985
Alzheimer's disease: a re-examination of the amyloid hypothesis
1998
Expression and regulation of brain metallothionein
1995
Exposure to physical and psychological stressors elevates plasma interleukin 6: relationship to the activation of hypothalamic-pituitary-adrenal axis.
1993
INFLAMMATION AND ALZHEIMERS DISEASE
2000
Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.
1996 StandoutNobel
Lack of Neurodegeneration in Transgenic Mice Overexpressing Mutant Amyloid Precursor Protein Is Associated with Increased Levels of Transthyretin and the Activation of Cell Survival Pathways
2002
Spherical aggregates of β-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3β
2003
Electrical stimulation of afferent vagus nerve induces IL-1β expression in the brain and activates HPA axis
2000
Transforming growth factor-beta 1 messenger RNA and protein expression in the pituitary gland: its action on prolactin secretion and lactotropic growth.
1992
Cachectin alters anterior pituitary hormone release by a direct action in vitro.
1989 StandoutNobel
A functional anatomical analysis of central pathways subserving the effects of interleukin-1 on stress-related neuroendocrine neurons
1994
Pituitary adenylate cyclase-activating polypeptide regulates prolactin promoter activity via a protein kinase A-mediated pathway that is independent of the transcriptional pathway employed by thyrotropin-releasing hormone.
1996
Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1.
1992
Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease
1997 StandoutNobel
Pituitary adenylate cyclase-activating polypeptide stimulates prolactin gene expression in a rat pituitary cell line.
1993
Oxidative Stress, Caloric Restriction, and Aging
1996 StandoutScience
Preparation and use of complementary peptides
1989
Maternal Care, Hippocampal Glucocorticoid Receptors, and Hypothalamic-Pituitary-Adrenal Responses to Stress
1997 StandoutScience
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Effects of GABA receptor agonists on [3H]dopamine release from median eminence and pituitary neurointermediate lobe
1985
Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease
2002
Intracranially administered anti-Abeta antibodies reduce beta-amyloid deposition by mechanisms both independent of and associated with microglial activation.
2003
Toxic Proteins in Neurodegenerative Disease
2002 Science
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
Alzheimer's Disease Is a Synaptic Failure
2002 StandoutScience
Fluorescent Sensors for Zn2+Based on a Fluorescein Platform:  Synthesis, Properties and Intracellular Distribution
2001 StandoutNobel
A central nervous system defect in biosynthesis of corticotropin-releasing hormone is associated with susceptibility to streptococcal cell wall-induced arthritis in Lewis rats.
1989
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Casting Metal Nanowires Within Discrete Self-Assembled Peptide Nanotubes
2003 StandoutScience
The interleukin-1 receptor in Raji human B-lymphoma cells. Molecular characterization and evidence for receptor-mediated activation of gene expression
1989
Potential Role of Microglia in Retinal Blood Vessel Formation
2006
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Endogenous brain IL-1 mediates LPS-induced anorexia and hypothalamic cytokine expression
2000
Transforming growth factor beta 1-like immunoreactivity in the pituitary gland of the rat: effect of estrogen.
1993
Control of Prolactin Release Induced by Suckling
1987
Characterization of in Vitro Dopamine Synthesis in the Median Eminence of Rats with Haloperidol-Induced Hyperprolactinemia and Bromocriptine-Induced Hypoprolactinemia
1986
The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease
2002
Peptidomimetic Regulation of Growth Hormone Secretion
1997
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1999 StandoutNature
The immunobiology of TSE diseases
2001
Interleukin-1 and interleukin-1 antagonism
1991 Standout
Microglial Activation and β-Amyloid Deposit Reduction Caused by a Nitric Oxide-Releasing Nonsteroidal Anti-Inflammatory Drug in Amyloid Precursor Protein Plus Presenilin-1 Transgenic Mice
2002
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
1999
Activation of vagal afferents after intravenous injection of interleukin-1beta: role of endogenous prostaglandins.
1998
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
Possible involvement of prostaglandin E in development of ACTH response in rats induced by human recombinant interleukin‐1.
1989

Works of Paul E. Gottschall being referenced

Number of A β Inoculations in APP+PS1 Transgenic Mice Influences Antibody Titers, Microglial Activation, and Congophilic Plaque Levels
2001
Neuropeptide Regulation of Interleukin-6 Production from the Pituitary: Stimulation by Pituitary Adenylate Cyclase Activating Polypeptide and Calcitonin Gene-Related Peptide*
1991
Intracranial administration of deglycosylated C-terminal-specific anti-Aβ antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice
2006
Increased Production of Matrix Metalloproteinases in Enriched Astrocyte and Mixed Hippocampal Cultures Treated with β‐Amyloid Peptides
1996
INTERLEUKIN-1 STIMULATES ACTH RELEASE BY AN INDIRECT ACTION WHICH REQUIRES ENDOGENOUS CORTICOTROPIN RELEASING FACTOR
1987
Characterization and Distribution of Binding Sites for the Hypothalamic Peptide, Pituitary Adenylate Cyclase-Activating Polypeptide*
1990
Presence of Immunoreactive Vasoactive Intestinal Polypeptide in Anterior Pituitary of Normal Male and Long Term Estrogen-Treated Female Rats: A Light Microscopic Immunohistochemical Study*
1990
Two High Affinity Binding Sites for Pituitary Adenylate Cyclase-Activating Polypeptide Have Different Tissue Distributions*
1991
Lectican proteoglycans, their cleaving metalloproteinases, and plasticity in the central nervous system extracellular microenvironment
2012
Deglycosylated Anti-Amyloid-β Antibodies Eliminate Cognitive Deficits and Reduce Parenchymal Amyloid with Minimal Vascular Consequences in Aged Amyloid Precursor Protein Transgenic Mice
2006
Molecular identification of receptor for pituitary adenylate cyclase activating polypeptide
1990
Increased production of gelatinase B (matrix metalloproteinase‐9) and interleukin‐6 by activated rat microglia in culture
1995
β-amyloid induction of gelatinase B secretion in cultured microglia
1996
Regulation of Matrix Metalloproteinase Expression in Astrocytes, Microglia and Neurons
1996
Adrenocorticotropin Release Induced by Intracerebroventricular Injection of Recombinant Human Interleukin-1 in Rats: Possible Involvement of Prostaglandin*
1988
INTERLEUKIN-1BETAINCREASES PROSTAGLANDIN E2IN RAT ASTROCYTE CULTURES: MODULATORY EFFECT OF NEUROPEPTIDES
1989
Trafficking CD11b-Positive Blood Cells Deliver Therapeutic Genes to the Brain of Amyloid-Depositing Transgenic Mice
2010
Regulation of interleukin-6 (IL-6) secretion in primary cultured rat astrocytes: synergism of interleukin-1 (IL-1) and pituitary adenylate cyclase activating polypeptide (PACAP)
1994
Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
2000 Nature
Identification of a high-affinity receptor for interleukin-1 beta in rat brain
1988
Discordance in the Effects of lnterleukin-1 on Rat Granulosa Cell Differentiation Induced by Follicle-Stimulating Hormone or Activators of Adenylate Cyclase1
1988
Cytochemical characterization of anterior pituitary target cells for the neuropeptide, pituitary adenylate cyclase activating polypeptide (PACAP), using biotinylated ligands
1993
Hypothalamic binding sites for pituitary adenylate cyclase activating polypeptide: characterization and molecular identification 1
1991
Glucocorticoid upregulation of interleukin 1 receptor expression in a glioblastoma cell line
1991
Stimulation of ACTH release by human interleukin-1β, but not by interleukin-1α, in conscious, freely-moving rats
1987
Possible recognition of the GnRH receptor by an antiserum against a peptide encoded by nucleotide sequence complementary to mRNA of a GnRH precursor peptide
1986
Decline of Tuberoinfundibular Dopaminergic Function Resulting from Chronic Hyperprolactinemia in Rats*
1984
Interleukin 1: an inhibitor of luteinizing hormone receptor formation in cultured rat granulosa cells
1988
L-Dopa Restores Amplitude of Growth Hormone Pulses in Old Male Rats to That Observed in Young Male Rats
1982
Growth Hormone Secretory Patterns in Young, Middle-Aged and Old Female Rats
1987
Persistence of Low Hypothalamic Dopaminergic Activity after Removal of Chronic Estrogen Treatment
1986
Damage to Hypothalamic Dopaminergic Neurons Is Associated with Development of Prolactin-Secreting Pituitary Tumors
1982 Science
Evidence for a Permanent Decline in Tuberoinfundibular Dopaminergic Neuronal Function after Chronic Estrogen Treatment Is Terminated in Fischer 344 Rats
1986
Uptake and release of [3H]dopamine by the median eminence: Evidence for presynaptic dopaminergic receptors and for dopaminergic feedback inhibition
1983
Involvement of organum vasculosum of lamina terminalis and preoptic area in interleukin 1 beta-induced ACTH release
1990
Rapid Increase in Plasma IL-6 after Hemorrhage, and Posthemorrhage Reduction of the IL-6 Response to LPS, in Conscious Rats: Interrelation with Plasma Corticosterone Levels
1994
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