Citation Impact
Citing Papers
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
Precise and Heritable Genome Editing in Evolutionarily Diverse Nematodes Using TALENs and CRISPR/Cas9 to Engineer Insertions and Deletions
2013 StandoutNobel
Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors
2009 StandoutScience
RNA-Guided Human Genome Engineering via Cas9
2013 StandoutScience
A Simple Cipher Governs DNA Recognition by TAL Effectors
2009 Science
The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target
2012 Science
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
2012 StandoutScienceNobel
Fungal Small RNAs Suppress Plant Immunity by Hijacking Host RNA Interference Pathways
2013 StandoutScience
A Bacterial Effector Acts as a Plant Transcription Factor and Induces a Cell Size Regulator
2007 Science
Modular recognition of nucleic acids by PUF, TALE and PPRproteins
2012
High-throughput genomic sequencing of cassava bacterial blight strains identifies conserved effectors to target for durable resistance
2012
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Transcription activator‐like effector nucleases (TALENs): A highly efficient and versatile tool for genome editing
2013
Addition of transcription activator‐like effector binding sites to a pathogen strain‐specific rice bacterial blight resistance gene makes it effective against additional strains and against bacterial leaf streak
2012
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription
2011
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
2016 StandoutNature
Broken TALEs: Transcription Activator-like Effectors Populate Partly Folded States
2016
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
2011
A transcription activator-like effector toolbox for genome engineering
2012
Comprehensive analysis of the specificity of transcription activator-like effector nucleases
2014
Characterization of AvrHah1, a novel AvrBs3‐like effector from Xanthomonas gardneri with virulence and avirulence activity
2008
Systematic testing of enzyme perturbation sensitivities via graded dCas9 modulation in Saccharomyces cerevisiae
2017
Classification and evolution of type II CRISPR-Cas systems
2014 StandoutNobel
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
Site Specific Mutation of the Zic2 Locus by Microinjection of TALEN mRNA in Mouse CD1, C3H and C57BL/6J Oocytes
2013
TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
2010
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
2011 Standout
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
How Xanthomonas type III effectors manipulate the host plant
2009
The emerging role of lncRNAs in cancer
2015 Standout
Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains
2012
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
2014 Standout
Enabling functional genomics with genome engineering
2015
Plant pathogenic bacterial type III effectors subdue host responses
2008
Molecular Insights into the Biosynthesis of Guadinomine: A Type III Secretion System Inhibitor
2012 StandoutNobel
Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes
2011
Plant immunity: towards an integrated view of plant–pathogen interactions
2010 Standout
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
2013 Standout
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
Detailed analysis of the DNA recognition motifs of the Xanthomonas type III effectors AvrBs3 and AvrBs3Δrep16
2009
TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction
2012
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Defining the core Arabidopsis thaliana root microbiome
2012 StandoutNature
Massively parallel determination and modeling of endonuclease substrate specificity
2014 StandoutNobel
FLASH assembly of TALENs for high-throughput genome editing
2012
Genome engineering using the CRISPR-Cas9 system
2013 Standout
Development and Applications of CRISPR-Cas9 for Genome Engineering
2014 Standout
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
2013 Standout
Improved Modeling of Side-Chain–Base Interactions and Plasticity in Protein–DNA Interface Design
2012 StandoutNobel
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Computational and Biochemical Analysis of the Xanthomonas Effector AvrBs2 and Its Role in the Modulation of Xanthomonas Type Three Effector Delivery
2011
TAL effectors: finding plant genes for disease and defense
2010
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
2012 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock
2014 StandoutNobel
TALEN or Cas9 – Rapid, Efficient and Specific Choices for Genome Modifications
2013
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
A TALE nuclease architecture for efficient genome editing
2010 Standout
Bacterial elicitation and evasion of plant innate immunity
2006
The plant immune system
2006 StandoutNature
A General Computational Approach for Repeat Protein Design
2014 StandoutNobel
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
2013 StandoutNobel
Genome-editing Technologies for Gene and Cell Therapy
2016
Emerging Concepts in Effector Biology of Plant-Associated Organisms
2009
From Guard to Decoy: A New Model for Perception of Plant Pathogen Effectors
2008
Pivoting the Plant Immune System from Dissection to Deployment
2013 StandoutScience
Extreme stability in de novo-designed repeat arrays is determined by unusually stable short-range interactions
2018 StandoutNobel
Rice xa13 Recessive Resistance to Bacterial Blight Is Defeated by Induction of the Disease Susceptibility Gene Os-11N3
2010
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Ancient class of translocated oomycete effectors targets the host nucleus
2010
TALENs: a widely applicable technology for targeted genome editing
2012
TAL Effectors: Customizable Proteins for DNA Targeting
2011 Science
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
Xanthomonas AvrBs3 Family-Type III Effectors: Discovery and Function
2010
Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors
2012 Science
Os8N3 is a host disease-susceptibility gene for bacterial blight of rice
2006
Rational design of a split-Cas9 enzyme complex
2015 StandoutNobel
Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus
2014 StandoutNobel
megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
2013 StandoutNobel
Engineering Plant Disease Resistance Based on TAL Effectors
2013
Xanthomonas T3S Effector XopN Suppresses PAMP-Triggered Immunity and Interacts with a Tomato Atypical Receptor-Like Kinase and TFT1
2009
De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks
2011
Two- and three-input TALE-based AND logic computation in embryonic stem cells
2013
Use and Abuse of RNAi to Study Mammalian Gene Function
2012 StandoutScienceNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Two type III effector genes of Xanthomonas oryzae pv. oryzae control the induction of the host genes OsTFIIA γ 1 and OsTFX1 during bacterial blight of rice
2007
Targeting DNA Double-Strand Breaks with TAL Effector Nucleases
2010
Works of Patrick Römer being referenced
Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors
2010
Plant Pathogen Recognition Mediated by Promoter Activation of the Pepper Bs3 Resistance Gene
2007 Science
RNA-seq pinpoints a Xanthomonas TAL-effector activated resistance gene in a large-crop genome
2012
Gene-for-gene-mediated recognition of nuclear-targeted AvrBs3-like bacterial effector proteins
2006
Physical delimitation of the pepper Bs3 resistance gene specifying recognition of the AvrBs3 protein from Xanthomonas campestris pv. vesicatoria
2006
Promoter elements of rice susceptibility genes are bound and activated by specific TAL effectors from the bacterial blight pathogen, Xanthomonas oryzae pv. oryzae
2010
Recognition of AvrBs3-Like Proteins Is Mediated by Specific Binding to Promoters of Matching Pepper Bs3 Alleles
2009
A single plant resistance gene promoter engineered to recognize multiple TAL effectors from disparate pathogens
2009