Citation Impact
Citing Papers
Yeast telomerase RNA: A flexible scaffold for protein subunits
2004 Nobel
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals
2021 StandoutNobel
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
2007 StandoutNobel
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Nonredundant roles for Stat5a/b in directly regulating Foxp3
2007
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Long noncoding RNAs in cancer: mechanisms of action and technological advancements
2016
Hallmarks of Cancer: The Next Generation
2011 Standout
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Functional characterization of the TERRA transcriptome at damaged telomeres
2014
Mechanisms in Eukaryotic Mismatch Repair
2006 StandoutNobel
RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells
2014
Promoter elements in the transcriptional activation of the human stromelysin-1 gene by the inflammatory cytokine, interleukin 1
1994
The DNA-damage response in human biology and disease
2009 StandoutNature
‘Green revolution’ genes encode mutant gibberellin response modulators
1999 StandoutNature
Control of somatic tissue differentiation by the long non-coding RNA TINCR
2012 StandoutNature
Inflammation and cancer
2002 StandoutNature
The Genetic Signatures of Noncoding RNAs
2009
TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres
2009
Protection of Epithelial Barrier Function by the Crohn's Disease Associated Gene Protein Tyrosine Phosphatase N2
2009
RPA regulates telomerase action by providing Est1p access to chromosome ends
2003
Molecular biology of the Ets family of transcription factors
2003
Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis
2007 StandoutNobel
Modular regulatory principles of large non-coding RNAs
2012 StandoutNature
Regulatory R-loops as facilitators of gene expression and genome stability
2020
Long Noncoding RNAs: Emerging Stars in Gene Regulation, Epigenetics and Human Disease
2014
An Indirect Effect of Stat5a in IL-2–Induced Proliferation: A Critical Role for Stat5a in IL-2–Mediated IL-2 Receptor α Chain Induction
1997
A new mathematical model for relative quantification in real-time RT-PCR
2001 Standout
Bottom-up de novo design of functional proteins with complex structural features
2021
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Telomeres and telomerase in cancer
2009
Indecent Exposure
2004
A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?
2011 Standout
Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells
2009
Opportunities and challenges in design and optimization of protein function
2024
Crystal Structure of a Tyrosine Phosphorylated STAT-1 Dimer Bound to DNA
1998
Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence
2013
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Activation of the MHC Class II Transactivator CIITA by Interferon-γ Requires Cooperative Interaction between Stat1 and USF-1
1998
A Brief History of De Novo Protein Design: Minimal, Rational, and Computational
2021
Interleukin-2 (IL-2)-mediated Induction of the IL-2 Receptor α Chain Gene
1997
Functional links between telomeres and proteins of the DNA-damage response
2004
Human Exonuclease I Is Required for 5′ and 3′ Mismatch Repair
2002 StandoutNobel
The Role of Long Noncoding RNAs in Central Nervous System and Neurodegenerative Diseases
2018
Beginning to Understand the End of the Chromosome
2004 Nobel
Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity
2005 StandoutNobel
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1
1998
Dissociation Time from DNA Determines Transcriptional Function in a STAT1 Linker Mutant
2002
Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita
2011
Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice
2002
Determination of enriched histone modifications in non-genic portions of the human genome
2009
Programmable RNA recognition and cleavage by CRISPR/Cas9
2014 StandoutNatureNobel
Physiological assembly and activity of human telomerase complexes
2007
Functional Association of Nmi with Stat5 and Stat1 in IL-2- and IFN γ-Mediated Signaling
1999
TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin
2018
Molecular Mechanisms of Long Noncoding RNAs
2011 Standout
Cdk1-Dependent Phosphorylation of Cdc13 Coordinates Telomere Elongation during Cell-Cycle Progression
2009 StandoutNobel
Phase transitions in the assembly of multivalent signalling proteins
2012 StandoutNature
Programmable synthetic receptors: the next-generation of cell and gene therapies
2024
The biogenesis and regulation of telomerase holoenzymes
2006
Distinct Activities of Exonuclease 1 and Flap Endonuclease 1 at Telomeric G4 DNA
2010
The major genetic risk factor for severe COVID-19 is inherited from Neanderthals
2020 StandoutNatureNobel
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
The hallmarks of cancer
2012 Standout
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Nuclear Bodies: Random Aggregates of Sticky Proteins or Crucibles of Macromolecular Assembly?
2009
Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of RNA-Chromatin Interactions
2011
The Hallmarks of Aging
2013 Standout
Telomeres and disease: Enter TERRA
2012
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
2019 Standout
Long noncoding RNAs: Novel insights into hepatocelluar carcinoma
2013
Computational design of novel protein–protein interactions – An overview on methodological approaches and applications
2022
Molecular basis of sun-induced premature skin ageing and retinoid antagonism
1996 StandoutNature
Modulation of telomere terminal structure by telomerase components in Candida albicans
2006
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
2010 StandoutNature
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA
2011 Nature
The Human RNA Surveillance Factor UPF1 Is Required for S Phase Progression and Genome Stability
2006
Novel roles for A‐type lamins in telomere biology and the DNA damage response pathway
2009
Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System
2015 StandoutNobel
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Both integrated and differential regulation of components of the IL-2/IL-2 receptor system
2006
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
STATs: transcriptional control and biological impact
2002 Standout
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
De novo protein design by inversion of the AlphaFold structure prediction network
2023
A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein
2004 StandoutNobel
TERRA: Long Noncoding RNA at Eukaryotic Telomeres
2010
Telomerase core components protect Candida telomeres from aberrant overhang accumulation
2007 StandoutNobel
Regulation of Telomerase by Telomeric Proteins
2004
Long Noncoding RNA and Cancer: A New Paradigm
2017 Standout
The Molecular Interactions That Stabilize RNA Tertiary Structure: RNA Motifs, Patterns, and Networks
2011
Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes
2019
JAKS AND STATS: Biological Implications
1998 Standout
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
The Structure and Function of Telomerase Reverse Transcriptase
2006
PARTICLE, a Triplex-Forming Long ncRNA, Regulates Locus-Specific Methylation in Response to Low-Dose Irradiation
2015
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2007 StandoutScience
The Eukaryotic Genome as an RNA Machine
2008 Science
Influence of Constitution and Charge on Radical Pairing Interactions in Tris-radical Tricationic Complexes
2016 StandoutNobel
Elf-1 and Stat5 Bind to a Critical Element in a New Enhancer of the Human Interleukin-2 Receptor α Gene
1996
How Shelterin Protects Mammalian Telomeres
2008 Standout
Role of the Stat4 N Domain in Receptor Proximal Tyrosine Phosphorylation
2000
An IL-2 response element in the human IL-2 receptor alpha chain promoter is a composite element that binds Stat5, Elf-1, HMG-I(Y) and a GATA family protein.
1996
Quantitative or semi-quantitative PCR: reality versus myth.
1992
Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA
2014
The Significance of Tetramerization in Promoter Recruitment by Stat5
1999
Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses
2012 StandoutNobel
Works of Patrick Reichenbach being referenced
Telomeric Repeat–Containing RNA and RNA Surveillance Factors at Mammalian Chromosome Ends
2007 Science
Mouse Interleukin-2 Receptor α Gene Expression
1995
Interaction of STAT5 Dimers on Two Low Affinity Binding Sites Mediates Interleukin 2 (IL-2) Stimulation of IL-2 Receptor α Gene Transcription
1997
1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2)
2016
Human CD8+ T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells
2001
The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase
2010
Author Correction: A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy
2020
A Human Homolog of Yeast Est1 Associates with Telomerase and Uncaps Chromosome Ends When Overexpressed
2003
A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy
2020
Protein–RNA and protein–protein interactions mediate association of human EST1A/SMG6 with telomerase
2007
Human Telomerase RNA Accumulation in Cajal Bodies Facilitates Telomerase Recruitment to Telomeres and Telomere Elongation
2007
Molecular Dissection of Telomeric Repeat-Containing RNA Biogenesis Unveils the Presence of Distinct and Multiple Regulatory Pathways
2010
Activity and interleukin 1 responsiveness of SV40 enhancer motifs in a rodent immature T cell line.
1990
A PCR-based assay for reporter gene expression.
1992
DNA Binding Specificity of Different STAT Proteins
2001
Characterization of a New Tissue-Specific Transcription Factor Binding to the Simian Virus 40 Enhancer TC-II (NF-κB) Element
1992
TIN2-Tethered TPP1 Recruits Human Telomerase to Telomeres In Vivo
2010
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action
2007
Elf-1 Contributes to the Function of the Complex Interleukin (IL)-2–responsive Enhancer in the Mouse IL-2 Receptor α Gene
1997