Citation Impact

Citing Papers

Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis
2014 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
2020 StandoutNobel
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN
2024 StandoutNobel
TOR Signaling in Growth and Metabolism
2006 Standout
The ROR nuclear orphan receptor subfamily: Critical regulators of multiple biological processes
2001
Abdominal obesity and metabolic syndrome
2006 StandoutNature
The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome
2016 Standout
Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptors, as a Novel Transcriptional Corepressor Molecule of Activating Protein-1, Nuclear Factor-κB, and Serum Response Factor
2000
mTOR Signaling in Growth Control and Disease
2012 Standout
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
Drug therapy of the metabolic syndrome: minimizing the emerging crisis in polypharmacy
2006
Regulation of Muscle Fiber Type and Running Endurance by PPARδ
2004
The genetics of ageing
2010 StandoutNature
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
2009 Standout
Vitamin D Deficiency
2007 Standout
Gene Model 129 (Gm129) Encodes a Novel Transcriptional Repressor That Modulates Circadian Gene Expression
2014 StandoutNobel
Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study
2017 Standout
Enhanced susceptibility ofstaggerer(RORαsg/sg) mice to lipopolysaccharide-induced lung inflammation
2005
Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists
2012 Nature
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Modulation of Retinoic Acid Receptor-related Orphan Receptor α and γ Activity by 7-Oxygenated Sterol Ligands
2009
Complete mapping of viral escape from neutralizing antibodies
2017
PPARs and the complex journey to obesity
2004
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Missing Pieces in the NF-κB Puzzle
2002 Standout
RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo
2012
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-δ deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy
2004
Mucins in ovarian cancer diagnosis and therapy
2009
X-Ray Structure of the hRORα LBD at 1.63 Å
2002
The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development
2014
High-Fat Diet Disrupts Behavioral and Molecular Circadian Rhythms in Mice
2007
Ligand regulation of retinoic acid receptor-related orphan receptors: implications for development of novel therapeutics
2010
Balanced pan-PPAR activator bezafibrate in combination with statin: comprehensive lipids control and diabetes prevention?
2012
The Benzenesulfoamide T0901317 [N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] Is a Novel Retinoic Acid Receptor-Related Orphan Receptor-α/γ Inverse Agonist
2009
TGF-β inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3
2001
REV-ERB and ROR nuclear receptors as drug targets
2014
Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
2016 Standout
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
2004 Nature
Mucin Granule Intraluminal Organization in Living Mucous/Goblet Cells
2005 StandoutNobel
The Structure and Assembly of Secreted Mucins
1999
AKT/PKB Signaling: Navigating the Network
2017 Standout
Challenges and Promise of a Hepatitis C Virus Vaccine
2019
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
2006 Standout
Glycocalyx Engineering with a Recycling Glycopolymer that Increases Cell Survival In Vivo
2015 StandoutNobel
Retinoic acid-related orphan receptors α and γ: key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivity
2013
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Mucins in cancer: protection and control of the cell surface
2003
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
2011 Standout
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
2008 StandoutNature
FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
2001 StandoutNobel
Differences in vitamin D status between countries in young adults and the elderly
1992
The MUC family: an obituary
2002
Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate
2022
Hierarchical Assembly of Model Cell Surfaces:  Synthesis of Mucin Mimetic Polymers and Their Display on Supported Bilayers
2007 StandoutNobel
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
BIOCHEMISTRY AND GENETICS OF VON WILLEBRAND FACTOR
1998 Standout
Vitamin D Deficiency and Secondary Hyperparathyroidism in the Elderly: Consequences for Bone Loss and Fractures and Therapeutic Implications
2001
Anatomy of β-Strands at Protein–Protein Interfaces
2014
Density Variant Glycan Microarray for Evaluating Cross-Linking of Mucin-like Glycoconjugates by Lectins
2012 StandoutNobel
An Optimized Hepatitis C Virus E2 Glycoprotein Core Adopts a Functional Homodimer That Efficiently Blocks Virus Entry
2016
Retinoid-Related Orphan Receptors (RORs): Critical Roles in Development, Immunity, Circadian Rhythm, and Cellular Metabolism
2009
Physical characterization of the MUC5AC mucin: a highly oligomeric glycoprotein whether isolated from cell culture or in vivo from respiratory mucous secretions
2000
CBP/p300 in cell growth, transformation, and development
2000
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
2002 StandoutNobel
Recombinant Hepatitis C Virus Envelope Glycoprotein Vaccine Elicits Antibodies Targeting Multiple Epitopes on the Envelope Glycoproteins Associated with Broad Cross-Neutralization
2014 StandoutNobel
Vitamin D Deficiency and Secondary Hyperparathyroidism in the Elderly: Consequences for Bone Loss and Fractures and Therapeutic Implications
2001 Standout
Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge
2019
Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression
2000
A Recombinant Hepatitis C Virus Genotype 1a E1/E2 Envelope Glycoprotein Vaccine Elicits Antibodies That Differentially Neutralize Closely Related 2a Strains through Interactions of the N-Terminal Hypervariable Region 1 of E2 with Scavenger Receptor B1
2019 StandoutNobel
Computational Prediction of the Heterodimeric and Higher-Order Structure of gpE1/gpE2 Envelope Glycoproteins Encoded by Hepatitis C Virus
2017 StandoutNobel
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
Chemically tunable mucin chimeras assembled on living cells
2015 StandoutNobel
Isoform-Specific Inhibition of RORα-Mediated Transcriptional Activation by Human FOXP3
2008
Native Folding of a Recombinant gpE1/gpE2 Heterodimer Vaccine Antigen from a Precursor Protein Fused with Fc IgG
2016 StandoutNobel
Role of the E2 Hypervariable Region (HVR1) in the Immunogenicity of a Recombinant Hepatitis C Virus Vaccine
2018 StandoutNobel
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
Interfacing Carbon Nanotubes with Living Cells
2006 StandoutNobel
Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody
2020 StandoutNobel
Noncovalent Cell Surface Engineering: Incorporation of Bioactive Synthetic Glycopolymers into Cellular Membranes
2008 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults--The Evidence Report. National Institutes of Health.
1998 Standout
Modified E2 Glycoprotein of Hepatitis C Virus Enhances Proinflammatory Cytokines and Protective Immune Response
2022 StandoutNobel
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel

Works of Patrick Lau being referenced

Structure-Based Design of Hepatitis C Virus E2 Glycoprotein Improves Serum Binding and Cross-Neutralization
2020
Homozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscle
2011
Identification and validation of the pathways and functions regulated by the orphan nuclear receptor, ROR alpha1, in skeletal muscle
2010
Exogenous expression of a dominant negative ROR 1 vector in muscle cells impairs differentiation: ROR 1 directly interacts with p300 and MyoD
1999
The Carboxyl-terminal Sequence of the Human Secretory Mucin, MUC6
1997
Retinoid-related orphan receptor   regulates several genes that control metabolism in skeletal muscle cells: links to modulation of reactive oxygen species production
2007
Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design
2019
Vitamin D status among patients with fractured neck of femur in Hong Kong
1990
Non-random Escape Pathways from a Broadly Neutralizing Human Monoclonal Antibody Map to a Highly Conserved Region on the Hepatitis C Virus E2 Glycoprotein Encompassing Amino Acids 412–423
2014
The Orphan Nuclear Receptor, RORα, Regulates Gene Expression That Controls Lipid Metabolism
2008
Rev-erbβ Regulates the Expression of Genes Involved in Lipid Absorption in Skeletal Muscle Cells
2004
RORα Regulates the Expression of Genes Involved in Lipid Homeostasis in Skeletal Muscle Cells
2004
Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice
2016
The Peroxisome Proliferator-Activated Receptor β/δ Agonist, GW501516, Regulates the Expression of Genes Involved in Lipid Catabolism and Energy Uncoupling in Skeletal Muscle Cells
2003
Cooperativity in Virus Neutralization by Human Monoclonal Antibodies to Two Adjacent Regions Located at the Amino Terminus of Hepatitis C Virus E2 Glycoprotein
2012
Mapping a Region of Hepatitis C Virus E2 That Is Responsible for Escape from Neutralizing Antibodies and a Core CD81-Binding Region That Does Not Tolerate Neutralization Escape Mutations
2011
Antigenicity and Immunogenicity of Differentially Glycosylated Hepatitis C Virus E2 Envelope Proteins Expressed in Mammalian and Insect Cells
2019
The Nuclear Receptor Corepressor N-CoR Regulates Differentiation: N-CoR Directly Interacts with MyoD
1999
Antibody Response to Hypervariable Region 1 Interferes with Broadly Neutralizing Antibodies to Hepatitis C Virus
2016
Characterization of the Retinoid Orphan-Related Receptor-α Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription
2002
Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design
2016
Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody
2012
Rankless by CCL
2026