Citation Impact
Citing Papers
Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia
2006 StandoutScience
Astrocytes: biology and pathology
2009 Standout
Recent advances in the application of solution NMR spectroscopy to multi-span integral membrane proteins
2009
Glutamate receptor ion channels
2005 Standout
Astrocytes in amyotrophic lateral sclerosis: direct effects on motor neuron survival
2009
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
Atropisomeric quinazolin-4-one derivatives are potent noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists
2001
Environmental and health effects of the herbicide glyphosate
2017 Standout
Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
2008
Molecular dissection of reactive astrogliosis and glial scar formation
2009 Standout
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Ido expression by dendritic cells: tolerance and tryptophan catabolism
2004 Standout
Minocycline delays disease onset and mortality in a transgenic model of ALS
2002
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Exploring biology with small organic molecules
2004 Nature
Pathobiology of ischaemic stroke: an integrated view
1999 Standout
Design, synthesis and evaluation of N-(substituted benzothiazol-2-yl)amides as anticonvulsant and neuroprotective
2012
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
Privileged scaffolds for library design and drug discovery
2010 Standout
Amyotrophic lateral sclerosis
2011 Standout
Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes
1993
Redox catalysis in organic electrosynthesis: basic principles and recent developments
2014 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
2005 StandoutNature
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Role of Detergents in Conformational Exchange of a G Protein-coupled Receptor
2012 StandoutNobel
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Structure-based drug screening for G-protein-coupled receptors
2012 StandoutNobel
Endogenous kynurenines as targets for drug discovery and development
2002
Competitive AMPA receptor antagonists
2006
Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study
2012 StandoutNobel
Dose-ranging study of riluzole in amyotrophic lateral sclerosis
1996 Standout
A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins
2012 StandoutNobel
High-throughput drug discovery: What can we expect from HTS?
2005
Design, synthesis and anticonvulsant evaluation of N-(benzo[d]thiazol-2-ylcarbamoyl)-2-methyl-4-oxoquinazoline-3(4H)-carbothioamide derivatives: A hybrid pharmacophore approach
2013
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
2017 StandoutNobel
Natural products in drug discovery
2008 Standout
Determining membrane protein structures: still a challenge!
2007
Controlled Microwave Heating in Modern Organic Synthesis
2004 Standout
Structural Model of the N-Methyl-D-aspartate Receptor Glycine Site Probed by Site-directed Chemical Coupling
2003
Lost in translation: Treatment trials in the SOD1 mouse and in human ALS
2007
A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry
2014 Standout
Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins
2010 StandoutNobel
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Minocycline: far beyond an antibiotic
2013 Standout
Tandem Facial Amphiphiles for Membrane Protein Stabilization
2010 StandoutNobel
Chemical and electrocatalytic cascade cyclization of Guareschi imides: ‘one-pot’ simple and efficient way to the 2,4-dioxo-3-azabicyclo[3.1.0]hexane scaffold
2013
Ethenesulfonyl Fluoride (ESF): An On-Water Procedure for the Kilogram-Scale Preparation
2016 StandoutNobel
Microwave-Assisted Synthesis in Water as Solvent
2007 Standout
ZK200775: A phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma
1998
The Glutamate Receptor Ion Channels
1999 Standout
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
Increasing cannabinoid levels by pharmacological and genetic manipulation delays disease progression in SOD1 mice
2006
Ischemic Cell Death in Brain Neurons
1999 Standout
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity
2007
A Phage-Assisted Continuous Selection Approach for Deep Mutational Scanning of Protein–Protein Interactions
2019
Assessing Atropisomer Axial Chirality in Drug Discovery and Development
2011 Standout
Excitotoxicity and Amyotrophic Lateral Sclerosis
2005
Evaluation and Biological Properties of Reactive Ligands for the Mapping of the Glycine Site on theN-Methyl-d -aspartate (NMDA) Receptor
1999
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Scalability of Microwave-Assisted Organic Synthesis. From Single-Mode to Multimode Parallel Batch Reactors
2003
AMPA receptors as a molecular target in epilepsy therapy
2013
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Synthesis and Structure−Activity Relationships of 1,2,3,4-Tetrahydroquinoline-2,3,4-trione 3-Oximes: Novel and Highly Potent Antagonists for NMDA Receptor Glycine Site
1996
Analogs of 3-Hydroxy-1H-1-benzazepine-2,5-dione: Structure−Activity Relationship atN-Methyl-d -aspartate Receptor Glycine Sites
1996
Works of Patrick Jimonet being referenced
RPR 119990, a Novel α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Antagonist: Synthesis, Pharmacological Properties, and Activity in an Animal Model of Amyotrophic Lateral Sclerosis
2001
Neuroprotective effects of RPR 104632, a novel antagonist at the glycine site of the NMDA receptor, in vitro
1996
Spiro-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one derivatives are mixed AMPA and NMDA glycine-site antagonists active in vivo
1999
Synthesis, anticonvulsant and neuroprotective activities of RP 66055, a riluzole derivative
1994
4,10-Dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives
2000
8-Methylureido-10-amino-10-methyl-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-ones: Highly In vivo Potent and Selective AMPA Receptor Antagonists
2000
Bioisosteres of 9-Carboxymethyl-4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent In Vivo AMPA antagonists with longer durations of action
2001
9-Carboxymethyl-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one-2-carbocylic Acid (RPR117824): Selective Anticonvulsive and Neuroprotective AMPA Antagonist
2002
8-Methylureido-4,5-dihydro-4-oxo-10H-imidazo[1,2-a]indeno-[1,2-e]pyrazines: highly potent in vivo AMPA antagonists
2000
Synthesis of anticonvulsive AMPA antagonists
2001
Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-8- and -9-carboxylic (acetic) acid AMPA antagonists
2000
RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis.
2001
Synthesis and sar of 2h-1,2,4-benzothiadiazine-1,1-dioxide-3- carboxylic acid derivatives as novel potent glycine antagonists of the nmda receptor-channel complex
1994
Strategies for designing GPCR-focused libraries and screening sets.
2004
A Rapid Filtration Assay for the Glycine Binding Site on the NMDA Receptor in Rat Cortical Membranes using [3H]Dichlorokynurenic Acid
1992
New Modalities, Technologies, and Partnerships in Probe and Lead Generation: Enabling a Mode-of-Action Centric Paradigm
2018
Indeno[1,2-b]pyrazin-2,3-diones: A New Class of Antagonists at the Glycine Site of the NMDA Receptor with Potent in Vivo Activity
2000
Synthesis and pharmacological properties of 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, a new competitive AMPA/KA receptor antagonist
1999