Citation Impact

Citing Papers

Oxidative Stress
2017 Standout
Nonshivering thermogenesis and its adequate measurement in metabolic studies
2010
Site-Specific Effects of PECAM-1 on Atherosclerosis in LDL Receptor–Deficient Mice
2008
Distinct fibroblast lineages determine dermal architecture in skin development and repair
2013 StandoutNature
Xanthine Oxidase Inhibition by Febuxostat Attenuates Experimental Atherosclerosis in Mice
2014
Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice
2011
Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E
1999
Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice
2013
Identification of the Interaction Site within Acyl-CoA:Cholesterol Acyltransferase 2 for the Isoform-specific Inhibitor Pyripyropene A
2008 StandoutNobel
The regulation of IL-10 production by immune cells
2010 Standout
Heparin-Protein Interactions
2002 Standout
Skin-specific Deletion of Stearoyl-CoA Desaturase-1 Alters Skin Lipid Composition and Protects Mice from High Fat Diet-induced Obesity
2009
Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice
2011
mTOR Signaling in Growth Control and Disease
2012 Standout
Gene targeting reveals the role of Oc90 as the essential organizer of the otoconial organic matrix
2007
Inflammatory links between obesity and metabolic disease
2011 Standout
Biology of Secretory Phospholipase A2
2008
Brown and beige fat: development, function and therapeutic potential
2013 Standout
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
2006 Standout
Chronic inflammation in the etiology of disease across the life span
2019 Standout
Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor–deficient mice
2003
Absence of ACAT-1 Attenuates Atherosclerosis but Causes Dry Eye and Cutaneous Xanthomatosis in Mice with Congenital Hyperlipidemia
2000
Phospholipase A2s: Developing drug targets for atherosclerosis
2010
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
2011 Standout
The Role of Cholesterol in the Pathogenesis of NASH
2015
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
Effects of 1-H-indole-3-glyoxamide (A-002) on concentration of secretory phospholipase A2 (PLASMA study): a phase II double-blind, randomised, placebo-controlled trial
2009
Macrophage-specific expression of group IIA sPLA2 results in accelerated atherogenesis by increasing oxidative stress
2005
The Science of Stroke: Mechanisms in Search of Treatments
2010 Standout
The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
2018
Atherosclerosis: current pathogenesis and therapeutic options
2011 Standout
Levels of sP-selectin and hs-CRP Decrease with Dietary Intervention with Selenium and Coenzyme Q10 Combined: A Secondary Analysis of a Randomized Clinical Trial
2015 StandoutNobel
Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials
2012
Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
2011
Macrophages in atherosclerosis: a dynamic balance
2013 Standout
Circulating levels of secretory- and lipoprotein-associated phospholipase A2 activities: relation to atherosclerotic plaques and future all-cause mortality
2012
Future Role for Selective Phospholipase A2 Inhibitors in the Prevention of Atherosclerotic Cardiovascular Disease
2009
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
CD36, a Class B Scavenger Receptor, Is Expressed on Microglia in Alzheimer's Disease Brains and Can Mediate Production of Reactive Oxygen Species in Response to β-Amyloid Fibrils
2002
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice
2000
Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis
2016
Noninvasive biomarkers in NAFLD and NASH — current progress and future promise
2018
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Non-alcoholic fatty liver disease
2021 Standout
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Farnesoid X Receptor Deficiency Induces Nonalcoholic Steatohepatitis in Low-Density Lipoprotein Receptor-Knockout Mice Fed a High-Fat Diet
2008
Absence of CD36 protects against atherosclerosis in ApoE knock-out mice with no additional protection provided by absence of scavenger receptor A I/II
2007
Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice
2005
Delayed catabolism of apoB-48 lipoproteins due to decreased heparan sulfate proteoglycan production in diabetic mice
2000
The synergistic inhibition of atherogenesis in apoE−/− mice between pravastatin and the sPLA2 inhibitor varespladib (A-002)
2008
Secretory phospholipase A2 of group IIA: Is it an offensive or a defensive player during atherosclerosis and other inflammatory diseases?
2005
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
Impact of Oxidative Stress on the Heart and Vasculature
2017
Apolipoprotein E and atherosclerosis: insight from animal and human studies
1999
Macrophage Secretory Phospholipase A2 Group X Enhances Anti-inflammatory Responses, Promotes Lipid Accumulation, and Contributes to Aberrant Lung Pathology
2008
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
Doubling Expression of the Low Density Lipoprotein Receptor by Truncation of the 3′-Untranslated Region Sequence Ameliorates Type III Hyperlipoproteinemia in Mice Expressing the Human ApoE2 Isoform
2001
Animal models of nonalcoholic fatty liver disease
2010
Nutritional model of steatohepatitis and metabolic syndrome in the Ossabaw miniature swine #
2009
Animal Models of Atopic Dermatitis
2008
Mast cells in atopic dermatitis
2009
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Reactive oxygen species in cardiovascular disease
2011
What We Talk About When We Talk About Fat
2014 Standout
Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins
2004 Standout
Lipotoxicity in macrophages: evidence from diseases associated with the metabolic syndrome
2009
Oxidation, lipoproteins, and atherosclerosis: which is wrong, the antioxidants or the theory?
2005
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Atherosclerosis
2000 StandoutNature
The Role of Adipose Tissue and Lipotoxicity in the Pathogenesis of Type 2 Diabetes
2010
Kupffer cells in non-alcoholic fatty liver disease: The emerging view
2009
Macrophages in obesity and non-alcoholic fatty liver disease: Crosstalk with metabolism
2019
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
Atherosclerosis
2001 Standout
Macrophage ABHD5 promotes colorectal cancer growth by suppressing spermidine production by SRM
2016
Role of Fat Body Lipogenesis in Protection against the Effects of Caloric Overload in Drosophila
2013
Enhanced extracellular lipid accumulation in acidic environments
2006
Soluble CD36 Ectodomain Binds Negatively Charged Diacylglycerol Ligands and Acts as a Co-Receptor for TLR2
2009 StandoutNobel
Lipid Oxidation and Peroxidation in CNS Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities
2009
Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications
2015
Biochemistry and Physiology of Mammalian Secreted Phospholipases A2
2008
Group V Secretory Phospholipase A 2 Promotes Atherosclerosis
2007
Inflammation and its Resolution as Determinants of Acute Coronary Syndromes
2014
Apolipoprotein E: Far More Than a Lipid Transport Protein
2000
Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor–deficient mice
2003
Scavenger Receptors in Atherosclerosis
2006
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
In Vivo Protective Role of Human Group IIA Phospholipase A2 against Experimental Anthrax
2005
Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves
2009 StandoutNobel
The pan‐caspase inhibitor Emricasan (IDN‐6556) decreases liver injury and fibrosis in a murine model of non‐alcoholic steatohepatitis
2014
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
2017 Standout
Lipoprotein-Associated and Secreted Phospholipases A 2 in Cardiovascular Disease
2010
Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition
2011
ACAT2 Is Localized to Hepatocytes and Is the Major Cholesterol-Esterifying Enzyme in Human Liver
2004 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease
2020 Standout
Interleukin‐10 overexpression in macrophages suppresses atherosclerosis in hyperlipidemic mice
2010
Emerging roles of secreted phospholipase A2 enzymes: Lessons from transgenic and knockout mice
2010
Liver Fibrosis: Mechanistic Concepts and Therapeutic Perspectives
2020
Characterization of the Fetal Blood Transcriptome and Proteome in Maternal Anti‐Fetal Rejection: Evidence of a Distinct and Novel Type of Human Fetal Systemic Inflammatory Response
2013
Mechanisms of Diabetic Complications
2013 Standout
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Reactive Oxygen Species in Metabolic and Inflammatory Signaling
2018 Standout
Preterm labor: One syndrome, many causes
2014 StandoutScience
Antifibrotic Activity of an Inhibitor of Group IIA Secretory Phospholipase A2 in Young Spontaneously Hypertensive Rats
2006
Roles of Vascular Oxidative Stress and Nitric Oxide in the Pathogenesis of Atherosclerosis
2017
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
A longitudinal study of whole body, tissue, and cellular physiology in a mouse model of fibrosing NASH with high fidelity to the human condition
2017
Loss of SR-A and CD36 Activity Reduces Atherosclerotic Lesion Complexity Without Abrogating Foam Cell Formation in Hyperlipidemic Mice
2008
Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives
2011 Standout
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
2006 Standout

Works of Patrick J. van Gorp being referenced

Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention
2016
Intrahepatic cholesterol influences progression, inhibition and reversal of non‐alcoholic steatohepatitis in hyperlipidemic mice
2010
Hyperlipidemia and cutaneous abnormalities in transgenic mice overexpressing human apolipoprotein C1.
1998
Specific immunization strategies against oxidized low-density lipoprotein: A novel way to reduce nonalcoholic steatohepatitis in mice
2012
Internalization of Modified Lipids by CD36 and SR-A Leads to Hepatic Inflammation and Lysosomal Cholesterol Storage in Kupffer Cells
2012
Plasma Cathepsin D Levels: A Novel Tool to Predict Pediatric Hepatic Inflammation
2015
Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis†
2008
Chorioamnionitis Induced Hepatic Inflammation and Disturbed Lipid Metabolism in Fetal Sheep
2010
Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice
1999
Role of Scavenger Receptor A and CD36 in Diet-Induced Nonalcoholic Steatohepatitis in Hyperlipidemic Mice
2010
Xanthine oxidase inhibitor tungsten prevents the development of atherosclerosis in ApoE knockout mice fed a Western-type diet
2006
In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway.
1996
Polymorphisms of the TUB Gene Are Associated with Body Composition and Eating Behavior in Middle-Aged Women
2008
The Cholesterol Derivative 27-Hydroxycholesterol Reduces Steatohepatitis in Mice
2012
Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates
2005
In the Absence of Endogenous Mouse Apolipoprotein E, Apolipoprotein E*2(Arg-158 → Cys) Transgenic Mice Develop More Severe Hyperlipoproteinemia than Apolipoprotein E*3-Leiden Transgenic Mice
1996
Understanding hyperlipidemia and atherosclerosis: lessons from genetically modified apoe and ldlr mice
2005
Identification of TUB as a Novel Candidate Gene Influencing Body Weight in Humans
2006
Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation
2013
Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition
2004
Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis
2011
Bone marrow‐specific caspase‐1/11 deficiency inhibits atherosclerosis development in Ldlr−/− mice
2015
Both Lipolysis and Hepatic Uptake of VLDL Are Impaired in Transgenic Mice Coexpressing Human Apolipoprotein E*3Leiden and Human Apolipoprotein C1
1996
Reprogramming macrophages to an anti‐inflammatory phenotype by helminth antigens reduces murine atherosclerosis
2013
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