Citation Impact

Citing Papers

Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae
2005
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
Batf3 Deficiency Reveals a Critical Role for CD8α + Dendritic Cells in Cytotoxic T Cell Immunity
2008 StandoutScience
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
Differential expression of matrix metalloproteinases and their tissue inhibitors in colon mucosa of patients with inflammatory bowel disease
2000
Cytokines and direct cell contact in synovitis: relevance to therapeutic intervention.
1999
Cell-cell interactions in synovitis. Interactions between T lymphocytes and synovial cells.
2000
Tuberculosis Associated with Infliximab, a Tumor Necrosis Factor α–Neutralizing Agent
2001 Standout
The Co‐Receptor Function of Murine CD41
1989
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
The many roles of CD40 in cell-mediated inflammatory responses
1996
Help for cytotoxic-T-cell responses is mediated by CD40 signalling
1998 StandoutNature
Rheumatoid arthritis
2016 Standout
THE NATURAL HISTORY AND PATHOGENESIS OF HIV INFECTION
1992
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks
2015
The level of CD8 expression can determine the outcome of thymic selection
1992 StandoutNobel
Efficacy of B-Cell–Targeted Therapy with Rituximab in Patients with Rheumatoid Arthritis
2004 Standout
Identity between the novel integrin β7 subunit and an antigen found highly expressed on intraepithelial lymphocytes in the small intestine
1991
Molecular Events Mediating T Cell Activation
1990
The Pathogenesis of Rheumatoid Arthritis
2011 Standout
Differential Activity of IL-12 and IL-23 in Mucosal and Systemic Innate Immune Pathology
2006
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Cytokine Pathways and Joint Inflammation in Rheumatoid Arthritis
2001 Standout
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
Transforming growth factor-β induces development of the TH17 lineage
2006 StandoutNature
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
1993 StandoutNature
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Interleukin-17 and Type 17 Helper T Cells
2009 Standout
Graves' Ophthalmopathy
2010 Standout
Identification of a CD4 binding site on the β2 domain of HLA-DR molecules
1992 Nature
Signal transduction by lymphocyte antigen receptors
1994 Standout
Alveolar macrophages: plasticity in a tissue-specific context
2014
The processing and presentation of mycobacterial antigens by human monocytes
1988
VLA Proteins in the Integrin Family: Structures, Functions, and Their Role on Leukocytes
1990
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
1994 StandoutNature
Adhesion receptors of the immune system
1990 StandoutNature
Crystal structure of an HIV-binding recombinant fragment of human CD4
1990 StandoutNatureNobel
Inhibition of the production and effects of interleukins‐1 and tumor necrosis factor α in rheumatoid arthritis
1995
Vβ-Specific Stimulation of Human T Cells by Staphylococcal Toxins
1989 Science
Atherosclerosis — An Inflammatory Disease
1999 Standout
Pro-and Anti-inflammatory Cytokines in Rheumatoid Arthritis
1997
Therapeutic strategies for rheumatoid arthritis
2003
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
Fatal Pulmonary Hypertension Associated with Short-Term Use of Fenfluramine and Phentermine
1997
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
1994 Standout
Development of anti-TNF therapy for rheumatoid arthritis
2002
The pivotal role of interleukin-1 in the clinical manifestations of rheumatoid arthritis
2003
Acute-Phase Proteins and Other Systemic Responses to Inflammation
1999 Standout
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
2014 Standout
Development and Selection of T Cells: Facts and Puzzles
1995
Imbalance between interstitial collagenase and tissue inhibitor of metalloproteinases 1 in synoviocytes and fibroblasts upon direct contact with stimulated T lymphocytes: Involvement of membrane-associated cytokines
1998
Lymphoproliferation in CTLA-4–Deficient Mice Is Mediated by Costimulation-Dependent Activation of CD4 + T Cells
1997 StandoutNobel
VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site
1990 Standout
DC-SIGN (CD209) Mediates Dengue Virus Infection of Human Dendritic Cells
2003 StandoutNobel
Sequestration From Immune CD4 + T Cells of Mycobacteria Growing in Human Macrophages
1993 StandoutScienceNobel
The Staphylococcal Enterotoxins and Their Relatives
1990 StandoutScience
PD-1 Inhibits Antiviral Immunity at the Effector Phase in the Liver
2003 StandoutNobel
Molecular characteristics of recombinant human CD4 as deduced from polymorphic crystals.
1990 StandoutNobel
The efficiency of acute infection of CD4+ T cells is markedly enhanced in the setting of antigen-specific immune activation.
1996 StandoutNobel
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
Facilitation of β Selection and Modification of Positive Selection in the Thymus of Pd-1–Deficient Mice
2000 StandoutNobel
ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS
1996 Standout
Dendritic Cells Initiate Immune Control of Epstein-Barr Virus Transformation of B Lymphocytes In Vitro
2003 StandoutNobel
Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site.
1990
Selective anergy of V beta 8+ T cells in human immunodeficiency virus-infected individuals.
1994 StandoutNobel
The MHC-Binding and gp120-Binding Functions of CD4 Are Separable
1989 Science
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
2006 Standout
The role of CD4 in T-cell activation: accessory molecule or co-receptor?
1989
Infection of Human Macrophages and Dendritic Cells with Mycobacterium tuberculosis Induces a Differential Cytokine Gene Expression That Modulates T Cell Response
2001
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
DC-SIGN Is the Major Mycobacterium tuberculosis Receptor on Human Dendritic Cells
2002
An Epstein-Barr virus-associated superantigen.
1996
Inhibition of lymphocyte mediated cytotoxicity by perforin antisense oligonucleotides.
1990
A Major Lung CD103 (αE)-β7 Integrin-Positive Epithelial Dendritic Cell Population Expressing Langerin and Tight Junction Proteins
2006
Selective expansion of T cells expressing T-cell receptor variable regions V beta 2 and V beta 8 in Kawasaki disease.
1992
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
A Cell Culture Model for T Lymphocyte Clonal Anergy
1990 StandoutScience
Regulation of Matrix Metalloproteinase Expression in Human Vascular Smooth Muscle Cells by T Lymphocytes
1997
Differential T Cell Function and Fate in Lymph Node and Nonlymphoid Tissues
2002
Structural analysis of the human immunodeficiency virus-binding domain of CD4. Epitope mapping with site-directed mutants and anti-idiotypes.
1989
Thymus and Autoimmunity: Production of CD25+CD4+ Naturally Anergic and Suppressive T Cells as a Key Function of the Thymus in Maintaining Immunologic Self-Tolerance
1999 StandoutNobel
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel

Works of Patrick Isler being referenced

ANTIGEN‐INDEPENDENT ACTIVATION OF T CELLS MEDIATED BY A NOVEL CELL SURFACE HETERODIMER (TPL35‐145)
1988
A positive signal is transduced via surface CD4 molecules
1989
Stimulation and proliferation of CD4+ peripheral blood T lymphocytes induced by an anti‐CD4 monoclonal antibody
1988
Alveolar Macrophages in Sarcoidosis Coexpress High Levels of CD86 (B7.2), CD40, and CD30L
1997
Human Lung Dendritic Cells Have an Immature Phenotype with Efficient Mannose Receptors
1999
Interleukin-12 Production by Human Alveolar Macrophages Is Controlled by the Autocrine Production of Interleukin-10
1999
Expression on human thymocytes of the idiotypic structures (Ti) from two leukemia T cell lines Jurkat and HPB‐ALL
1986
Direct contact between T lymphocytes and monocytes is a major pathway for induction of metalloproteinase expression.
1994
Cell surface glycoproteins expressed on activated human T cells induce production of interleukin-1 beta by monocytic cells: a possible role of CD69.
1993
Differential regulation of tumor necrosing factor-alpha (TNF-alpha) and interleukin-10 (IL-10) secretion by protein kinase and phosphatase inhibitors in human alveolar macrophages.
1999
Contact-dependent stimulation of monocytic cells and neutrophils by stimulated human T-cell clones.
1995
A novel 90‐kDa polypeptide (Tp90) possibly involved in an antigen‐independent pathway of T cell activation
1987
Phorbol 12‐myristate 13‐acetate induces surface expression of T3 on human immature T cell lines with and without concomitant expression of the T cell antigen receptor complex
1987
[Metastatic carcinoid of the small intestine with severe valvular defects especially in the right part of the heart and with pulmonary stenosis; a peculiar symptom complex].
1953
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